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Entry version 143 (12 Aug 2020)
Sequence version 1 (01 Jun 2003)
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Protein

Sperm-associated antigen 1

Gene

Spag1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May play a role in the cytoplasmic assembly of the ciliary dynein arms (By similarity). May play a role in fertilization. Binds GTP and has GTPase activity (By similarity).By similarity

Miscellaneous

Antibodies against SPAG1 interfere with fertilization.By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi756 – 763GTPSequence analysis8

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionHydrolase
Biological processFertilization
LigandGTP-binding, Nucleotide-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Sperm-associated antigen 1
Alternative name(s):
Infertility-related sperm protein Spag-1
TPR-containing protein involved in spermatogenesis
Short name:
TPIS
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Spag1
Synonyms:Tpis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 15

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1349387, Spag1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001063251 – 901Sperm-associated antigen 1Add BLAST901

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei351PhosphoserineCombined sources1
Modified residuei359PhosphoserineCombined sources1
Modified residuei703PhosphoserineBy similarity1
Modified residuei739PhosphoserineCombined sources1
Modified residuei740PhosphoserineCombined sources1
Modified residuei766PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q80ZX8

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q80ZX8

PeptideAtlas

More...
PeptideAtlasi
Q80ZX8

PRoteomics IDEntifications database

More...
PRIDEi
Q80ZX8

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q80ZX8

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q80ZX8

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Detected in cerebellum, tongue, esophagus, forestomach, sperm and testis.1 Publication

<p>This subsection of the 'Expression' section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified 'at the protein level'.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

Expression is very low in embryonic epidermis at 13.5 dpc and increases from 14.5 dpc to 16.5 dpc. In young mice expression increases in the testis of 2 to 6 weeks old animals, and then remains stable.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000037617, Expressed in embryo and 213 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q80ZX8, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q80ZX8, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
205078, 4 interactors

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000047335

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q80ZX8, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q80ZX8

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati213 – 246TPR 1Add BLAST34
Repeati247 – 279TPR 2Add BLAST33
Repeati280 – 313TPR 3Add BLAST34
Repeati430 – 464TPR 4Add BLAST35
Repeati472 – 505TPR 5Add BLAST34
Repeati507 – 539TPR 6Add BLAST33
Repeati606 – 639TPR 7Add BLAST34
Repeati640 – 673TPR 8Add BLAST34

Keywords - Domaini

Repeat, TPR repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1124, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000154697

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_008405_1_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q80ZX8

KEGG Orthology (KO)

More...
KOi
K19870

Identification of Orthologs from Complete Genome Data

More...
OMAi
QYRKAYV

Database of Orthologous Groups

More...
OrthoDBi
1070087at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q80ZX8

TreeFam database of animal gene trees

More...
TreeFami
TF106251

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.25.40.10, 3 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR025986, RPAP3-like_C
IPR013026, TPR-contain_dom
IPR011990, TPR-like_helical_dom_sf
IPR001440, TPR_1
IPR019734, TPR_repeat

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF13877, RPAP3_C, 1 hit
PF00515, TPR_1, 2 hits
PF13181, TPR_8, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00028, TPR, 8 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48452, SSF48452, 3 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50005, TPR, 6 hits
PS50293, TPR_REGION, 4 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform 1 (identifier: Q80ZX8-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MTAKAKDCPS LWGFGTTKTF KIPIEHLDFK YIENCSDVKH LEKILYVLRS
60 70 80 90 100
GEEGYYPELT EFCEKCLTNL APKSRALRKD KPAETASSFS AEEWEKIDSD
110 120 130 140 150
LKSWVSEIKR EENTCHFHDP ENHPGVEDPL PPVRGSTCCP HSGKETYSKS
160 170 180 190 200
KTAKKRIPRD YAEWDKFDVE KECSKIDEDY KEKTVINNKA HLSKIETKIE
210 220 230 240 250
TAGLTEKEKS FLANREKGKG NEAFYSGDYE EAVMYYTRSL SALPTAIAYN
260 270 280 290 300
NRAQAEIKLQ RWSSALEDCE KALELDPGNV KALLRRATTY KHQNKLQEAV
310 320 330 340 350
DDLRKVLQVE PDNDLAKKTL SEVERDLKNS EPVSELQTKG KRMVIEEVEN
360 370 380 390 400
SGDEGGKGSA DEREDGGSDE AAMGNIQKKL MVRRSEGGRR SRRGRTPGPR
410 420 430 440 450
AEQQGGLRET ATASTGDSHY PEEPRAADNP SGLKRRGNEL FRGGQFAEAA
460 470 480 490 500
AQYSVAIAQL EPTGSANADE LSILYSNRAA CYLKEGNCRD CIQDCNRALE
510 520 530 540 550
LHPFSVKPLL RRAMAYETLE QYRNAYVDYK TVLQIDCGIQ LASDSANRIA
560 570 580 590 600
RILTELDGSK WRERLPPIPA VPTSEPLRVW LPAAETPDQD PCPNNCMPSI
610 620 630 640 650
TDEKMFQALK EEGNQLVKDK NYKDAISKYN ECLKINSKAC AIYTNRALCY
660 670 680 690 700
LKLGQFEEAK LDCEQALQID GENVKASHRL ALAQKGLENC RESGVDPSQV
710 720 730 740 750
LLSPDSSEAA RHLDTKNDTA PPSKGRERRR IQVQEVDGSS DEEPERPAEA
760 770 780 790 800
SATSAPARDG VEDGGSAEPA EKLDVSKPTN AYEFGQVLST ISARKDEEAC
810 820 830 840 850
AHLLAITAPK DLPLLLSNKL EGDTFLLLIQ SLKSHLVAKD PSLVYEHLLY
860 870 880 890 900
LSKAERFKTM LTLINKGQKE QMAQLFDGLS DTQSDGLTAE DVQALRRQYE

L
Length:901
Mass (Da):100,670
Last modified:June 1, 2003 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iC8D14100AD00D69F
GO
Isoform 2 (identifier: Q80ZX8-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-372: Missing.

Show »
Length:529
Mass (Da):58,511
Checksum:i8230355A0D615C8C
GO
Isoform 3 (identifier: Q80ZX8-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-233: Missing.

Show »
Length:668
Mass (Da):73,972
Checksum:i0BD1BC0558F357F8
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A2I3BPL5A0A2I3BPL5_MOUSE
Sperm-associated antigen 1
Spag1
77Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAC27944 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti115C → R in AAF06160 (PubMed:10527845).Curated1
Sequence conflicti364E → A in AAF06160 (PubMed:10527845).Curated1
Sequence conflicti419H → Y in AAF06160 (PubMed:10527845).Curated1
Sequence conflicti419H → Y in AAF06161 (PubMed:10527845).Curated1
Sequence conflicti664E → D in AAF06160 (PubMed:10527845).Curated1
Sequence conflicti664E → D in AAF06161 (PubMed:10527845).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0126841 – 372Missing in isoform 2. 1 PublicationAdd BLAST372
Alternative sequenceiVSP_0126851 – 233Missing in isoform 3. 1 PublicationAdd BLAST233

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF181252 mRNA Translation: AAF06160.1
AF181253 mRNA Translation: AAF06161.1
AK032601 mRNA Translation: BAC27944.1 Different initiation.
BC046313 mRNA Translation: AAH46313.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS37061.1 [Q80ZX8-1]

Protein sequence database of the Protein Information Resource

More...
PIRi
JC7111

NCBI Reference Sequences

More...
RefSeqi
NP_036161.2, NM_012031.3 [Q80ZX8-1]
XP_006520138.1, XM_006520075.2
XP_006520139.1, XM_006520076.3 [Q80ZX8-1]
XP_006520141.1, XM_006520078.3 [Q80ZX8-3]
XP_006520142.1, XM_006520079.3
XP_017172125.1, XM_017316636.1 [Q80ZX8-1]
XP_017172126.1, XM_017316637.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000047348; ENSMUSP00000047335; ENSMUSG00000037617 [Q80ZX8-1]
ENSMUST00000171205; ENSMUSP00000132233; ENSMUSG00000037617 [Q80ZX8-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
26942

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:26942

UCSC genome browser

More...
UCSCi
uc007vmn.1, mouse [Q80ZX8-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF181252 mRNA Translation: AAF06160.1
AF181253 mRNA Translation: AAF06161.1
AK032601 mRNA Translation: BAC27944.1 Different initiation.
BC046313 mRNA Translation: AAH46313.1
CCDSiCCDS37061.1 [Q80ZX8-1]
PIRiJC7111
RefSeqiNP_036161.2, NM_012031.3 [Q80ZX8-1]
XP_006520138.1, XM_006520075.2
XP_006520139.1, XM_006520076.3 [Q80ZX8-1]
XP_006520141.1, XM_006520078.3 [Q80ZX8-3]
XP_006520142.1, XM_006520079.3
XP_017172125.1, XM_017316636.1 [Q80ZX8-1]
XP_017172126.1, XM_017316637.1

3D structure databases

SMRiQ80ZX8
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi205078, 4 interactors
STRINGi10090.ENSMUSP00000047335

PTM databases

iPTMnetiQ80ZX8
PhosphoSitePlusiQ80ZX8

Proteomic databases

EPDiQ80ZX8
PaxDbiQ80ZX8
PeptideAtlasiQ80ZX8
PRIDEiQ80ZX8

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
26172, 163 antibodies

Genome annotation databases

EnsembliENSMUST00000047348; ENSMUSP00000047335; ENSMUSG00000037617 [Q80ZX8-1]
ENSMUST00000171205; ENSMUSP00000132233; ENSMUSG00000037617 [Q80ZX8-1]
GeneIDi26942
KEGGimmu:26942
UCSCiuc007vmn.1, mouse [Q80ZX8-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
6674
MGIiMGI:1349387, Spag1

Phylogenomic databases

eggNOGiKOG1124, Eukaryota
GeneTreeiENSGT00940000154697
HOGENOMiCLU_008405_1_0_1
InParanoidiQ80ZX8
KOiK19870
OMAiQYRKAYV
OrthoDBi1070087at2759
PhylomeDBiQ80ZX8
TreeFamiTF106251

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
26942, 3 hits in 18 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Spag1, mouse

Protein Ontology

More...
PROi
PR:Q80ZX8
RNActiQ80ZX8, protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000037617, Expressed in embryo and 213 other tissues
ExpressionAtlasiQ80ZX8, baseline and differential
GenevisibleiQ80ZX8, MM

Family and domain databases

Gene3Di1.25.40.10, 3 hits
InterProiView protein in InterPro
IPR025986, RPAP3-like_C
IPR013026, TPR-contain_dom
IPR011990, TPR-like_helical_dom_sf
IPR001440, TPR_1
IPR019734, TPR_repeat
PfamiView protein in Pfam
PF13877, RPAP3_C, 1 hit
PF00515, TPR_1, 2 hits
PF13181, TPR_8, 1 hit
SMARTiView protein in SMART
SM00028, TPR, 8 hits
SUPFAMiSSF48452, SSF48452, 3 hits
PROSITEiView protein in PROSITE
PS50005, TPR, 6 hits
PS50293, TPR_REGION, 4 hits

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSPAG1_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q80ZX8
Secondary accession number(s): Q8CCK7, Q9QZJ3, Q9QZJ4
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 2005
Last sequence update: June 1, 2003
Last modified: August 12, 2020
This is version 143 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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