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UniProtKB - Q80ZU0 (ARL5A_MOUSE)
Protein
ADP-ribosylation factor-like protein 5A
Gene
Arl5a
Organism
Mus musculus (Mouse)
Status
Functioni
Lacks ADP-ribosylation enhancing activity.
By similaritySites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Binding sitei | 159 | GTP; via amide nitrogenBy similarity | 1 |
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Nucleotide bindingi | 23 – 30 | GTPBy similarity | 8 | |
Nucleotide bindingi | 66 – 70 | GTPBy similarity | 5 | |
Nucleotide bindingi | 125 – 128 | GTPBy similarity | 4 |
GO - Molecular functioni
- GTPase activity Source: InterPro
- GTP binding Source: GO_Central
GO - Biological processi
- intracellular protein transport Source: GO_Central
- protein localization to Golgi membrane Source: MGI
- vesicle-mediated transport Source: GO_Central
Keywordsi
Ligand | GTP-binding, Nucleotide-binding |
Names & Taxonomyi
Protein namesi | Recommended name: ADP-ribosylation factor-like protein 5A |
Gene namesi | Name:Arl5a Synonyms:Arl5 |
Organismi | Mus musculus (Mouse) |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Proteomesi |
|
Organism-specific databases
MGIi | MGI:1922673, Arl5a |
VEuPathDBi | HostDB:ENSMUSG00000036093 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Initiator methioninei | RemovedSequence analysis | |||
ChainiPRO_0000207468 | 2 – 179 | ADP-ribosylation factor-like protein 5AAdd BLAST | 178 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Lipidationi | 2 | N-myristoyl glycineSequence analysis | 1 |
Keywords - PTMi
Lipoprotein, MyristateProteomic databases
MaxQBi | Q80ZU0 |
PaxDbi | Q80ZU0 |
PRIDEi | Q80ZU0 |
ProteomicsDBi | 283223 |
PTM databases
PhosphoSitePlusi | Q80ZU0 |
Expressioni
Gene expression databases
Bgeei | ENSMUSG00000036093, Expressed in optic fissure and 326 other tissues |
ExpressionAtlasi | Q80ZU0, baseline and differential |
Genevisiblei | Q80ZU0, MM |
Interactioni
Protein-protein interaction databases
STRINGi | 10090.ENSMUSP00000041756 |
Miscellaneous databases
RNActi | Q80ZU0, protein |
Family & Domainsi
Sequence similaritiesi
Phylogenomic databases
eggNOGi | KOG0070, Eukaryota |
GeneTreei | ENSGT00940000154714 |
HOGENOMi | CLU_040729_9_1_1 |
InParanoidi | Q80ZU0 |
OMAi | IWRLFSH |
OrthoDBi | 1417432at2759 |
PhylomeDBi | Q80ZU0 |
TreeFami | TF105465 |
Family and domain databases
Gene3Di | 3.40.50.300, 1 hit |
InterProi | View protein in InterPro IPR027417, P-loop_NTPase IPR005225, Small_GTP-bd_dom IPR024156, Small_GTPase_ARF IPR006689, Small_GTPase_ARF/SAR |
PANTHERi | PTHR11711, PTHR11711, 1 hit |
Pfami | View protein in Pfam PF00025, Arf, 1 hit |
PRINTSi | PR00328, SAR1GTPBP |
SMARTi | View protein in SMART SM00178, SAR, 1 hit |
SUPFAMi | SSF52540, SSF52540, 1 hit |
TIGRFAMsi | TIGR00231, small_GTP, 1 hit |
PROSITEi | View protein in PROSITE PS51417, ARF, 1 hit |
i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
Q80ZU0-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MGILFTRIWR LFNHQEHKVI IVGLDNAGKT TILYQFSMNE VVHTSPTIGS
60 70 80 90 100
NVEEIVVNNT RFLMWDIGGQ ESLRPSWNTY YTNTEFVIVV VDSTDRERIS
110 120 130 140 150
VTREELYKML AHEDLRKAGL LIFANKQDVK ECMTVAEISQ FLKLTSIKDH
160 170
QWHIQACCAL TGEGLCQGLE WMMSRLKIR
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC048170 mRNA Translation: AAH48170.1 |
CCDSi | CCDS16033.1 |
RefSeqi | NP_892039.1, NM_182994.2 |
Genome annotation databases
Ensembli | ENSMUST00000036541; ENSMUSP00000041756; ENSMUSG00000036093 |
GeneIDi | 75423 |
KEGGi | mmu:75423 |
UCSCi | uc008jqy.1, mouse |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC048170 mRNA Translation: AAH48170.1 |
CCDSi | CCDS16033.1 |
RefSeqi | NP_892039.1, NM_182994.2 |
3D structure databases
AlphaFoldDBi | Q80ZU0 |
SMRi | Q80ZU0 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 10090.ENSMUSP00000041756 |
PTM databases
PhosphoSitePlusi | Q80ZU0 |
Proteomic databases
MaxQBi | Q80ZU0 |
PaxDbi | Q80ZU0 |
PRIDEi | Q80ZU0 |
ProteomicsDBi | 283223 |
Protocols and materials databases
Antibodypediai | 33675, 66 antibodies from 16 providers |
DNASUi | 75423 |
Genome annotation databases
Ensembli | ENSMUST00000036541; ENSMUSP00000041756; ENSMUSG00000036093 |
GeneIDi | 75423 |
KEGGi | mmu:75423 |
UCSCi | uc008jqy.1, mouse |
Organism-specific databases
CTDi | 26225 |
MGIi | MGI:1922673, Arl5a |
VEuPathDBi | HostDB:ENSMUSG00000036093 |
Phylogenomic databases
eggNOGi | KOG0070, Eukaryota |
GeneTreei | ENSGT00940000154714 |
HOGENOMi | CLU_040729_9_1_1 |
InParanoidi | Q80ZU0 |
OMAi | IWRLFSH |
OrthoDBi | 1417432at2759 |
PhylomeDBi | Q80ZU0 |
TreeFami | TF105465 |
Miscellaneous databases
BioGRID-ORCSi | 75423, 1 hit in 70 CRISPR screens |
ChiTaRSi | Arl5a, mouse |
PROi | PR:Q80ZU0 |
RNActi | Q80ZU0, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSMUSG00000036093, Expressed in optic fissure and 326 other tissues |
ExpressionAtlasi | Q80ZU0, baseline and differential |
Genevisiblei | Q80ZU0, MM |
Family and domain databases
Gene3Di | 3.40.50.300, 1 hit |
InterProi | View protein in InterPro IPR027417, P-loop_NTPase IPR005225, Small_GTP-bd_dom IPR024156, Small_GTPase_ARF IPR006689, Small_GTPase_ARF/SAR |
PANTHERi | PTHR11711, PTHR11711, 1 hit |
Pfami | View protein in Pfam PF00025, Arf, 1 hit |
PRINTSi | PR00328, SAR1GTPBP |
SMARTi | View protein in SMART SM00178, SAR, 1 hit |
SUPFAMi | SSF52540, SSF52540, 1 hit |
TIGRFAMsi | TIGR00231, small_GTP, 1 hit |
PROSITEi | View protein in PROSITE PS51417, ARF, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | ARL5A_MOUSE | |
Accessioni | Q80ZU0Primary (citable) accession number: Q80ZU0 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | May 10, 2004 |
Last sequence update: | June 1, 2003 | |
Last modified: | May 25, 2022 | |
This is version 133 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- MGD cross-references
Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot - SIMILARITY comments
Index of protein domains and families