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Entry version 130 (16 Oct 2019)
Sequence version 1 (01 Jun 2003)
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Protein

Protein LYRIC

Gene

Mtdh

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Downregulates SLC1A2/EAAT2 promoter activity when expressed ectopically. Activates the nuclear factor kappa-B (NF-kappa-B) transcription factor. Promotes anchorage-independent growth of immortalized melanocytes and astrocytes which is a key component in tumor cell expansion. Promotes lung metastasis and also has an effect on bone and brain metastasis, possibly by enhancing the seeding of tumor cells to the target organ endothelium. Induces chemoresistance (By similarity).By similarity

Caution

Was originally thought to be a type II membrane protein but this is inconsistent with the results of multiple phosphorylation studies because this topology would locate the phosphorylation sites in the lumen or extracellularly rather than in the cytoplasm.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein LYRIC
Alternative name(s):
3D3/LYRIC
Lysine-rich CEACAM1 co-isolated protein
Metadherin
Metastasis adhesion protein
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Mtdh
Synonyms:Lyric
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 15

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1914404 Mtdh

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 48LumenalSequence analysisAdd BLAST48
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei49 – 69HelicalSequence analysisAdd BLAST21
Topological domaini70 – 579CytoplasmicSequence analysisAdd BLAST510

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cell junction, Cytoplasm, Endoplasmic reticulum, Membrane, Nucleus, Tight junction

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000845341 – 579Protein LYRICAdd BLAST579

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei179PhosphoserineBy similarity1
Modified residuei215PhosphoserineBy similarity1
Modified residuei250PhosphoserineBy similarity1
Modified residuei263N6-acetyllysineCombined sources1
Modified residuei297PhosphoserineCombined sources1
Modified residuei303PhosphoserineBy similarity1
Modified residuei308PhosphoserineBy similarity1
Modified residuei341PhosphoserineBy similarity1
Modified residuei366PhosphoserineBy similarity1
Modified residuei412PhosphoserineBy similarity1
Modified residuei423PhosphoserineBy similarity1
Modified residuei454PhosphoserineBy similarity1
Modified residuei475PhosphoserineBy similarity1
Modified residuei491PhosphoserineBy similarity1
Modified residuei493PhosphoserineBy similarity1
Modified residuei565PhosphoserineCombined sources1

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

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EPDi
Q80WJ7

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q80WJ7

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q80WJ7

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q80WJ7

PeptideAtlas

More...
PeptideAtlasi
Q80WJ7

PRoteomics IDEntifications database

More...
PRIDEi
Q80WJ7

Consortium for Top Down Proteomics

More...
TopDownProteomicsi
Q80WJ7

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q80WJ7

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q80WJ7

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
Q80WJ7

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

In the mammary gland, expressed at the apical surface of epithelial cells lining ducts, as well as in the mammary fat pad. Not detected in the spleen, kidney, lung, or skin; minute amounts seen in the liver. Expressed in Purkinje neurons in the early postnatal and adult cerebellum. Overexpressed in mammary tumors (at protein level).1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000022255 Expressed in 286 organ(s), highest expression level in ear

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q80WJ7 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q80WJ7 MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with BCCIP, CREBBP/CBP and RELA/p65.

By similarity

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

WithEntry#Exp.IntActNotes
Snd1Q78PY74EBI-774530,EBI-529864

GO - Molecular functioni

Protein-protein interaction databases

Protein interaction database and analysis system

More...
IntActi
Q80WJ7, 8 interactors

Molecular INTeraction database

More...
MINTi
Q80WJ7

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000022865

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q80WJ7

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 71Activation of NF-kappa-BBy similarityAdd BLAST71
Regioni72 – 168Interaction with BCCIPBy similarityAdd BLAST97
Regioni100 – 204Interaction with RELABy similarityAdd BLAST105
Regioni378 – 440Lung-homing for mammary tumorsAdd BLAST63

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi59 – 67Poly-Leu9
Compositional biasi438 – 448Poly-LysAdd BLAST11
Compositional biasi570 – 574Poly-Lys5

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

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eggNOGi
ENOG410IIV9 Eukaryota
ENOG410YF4D LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000154181

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q80WJ7

Identification of Orthologs from Complete Genome Data

More...
OMAi
NYEEPPV

Database of Orthologous Groups

More...
OrthoDBi
1432988at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q80WJ7

TreeFam database of animal gene trees

More...
TreeFami
TF331350

Family and domain databases

Integrated resource of protein families, domains and functional sites

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InterProi
View protein in InterPro
IPR031402 LYRIC

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF15686 LYRIC, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 6 potential isoforms that are computationally mapped.Show allAlign All

Q80WJ7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAARSWQDEL AQQAEEGSAR LRELLSVGLG FLRTELGLDL GLEPKRYPGW
60 70 80 90 100
VILVGTGALG LLLLFLLGYG WAAACAGARK KRRSPPRKRE EAAPPTPAPD
110 120 130 140 150
DLAQLKNLRS EEQKKKNRKK LPEKPKPNGR TVEVPEDEVV RNPRSITAKQ
160 170 180 190 200
APETDKKNEK SKKNKKKSKS DAKAVQNSSR HDGKEVDEGA WETKISHREK
210 220 230 240 250
RQQRKRDKVL TDSGSLDSTI PGIENIITVT TEQLTTASFP VGSKKNKGDS
260 270 280 290 300
HLNVQVSNFK SGKGDSTLQV SSRLNENLTV NGGGWSEKSV KLSSQLSEEK
310 320 330 340 350
WNSVPPASAG KRKTEPSAWT QDTGDTNANG KDWGRNWSDR SIFSGIGSTA
360 370 380 390 400
EPVSQSTTSD YQWDVSRNQP YIDDEWSGLN GLSSADPSSD WNAPAEEWGN
410 420 430 440 450
WVDEDRASLL KSQEPISNDQ KVSDDDKEKG EGALPTGKSK KKKKKKKKQG
460 470 480 490 500
EDNSHTQDTE DLEKDTREEL PVNTSKARPK QEKACSLKTM STSDPAEVLI
510 520 530 540 550
KNSQPVKTLP PAISAEPSIT LSKGDSDNSS SQVPPMLQDT DKPKSNAKQN
560 570
SVPPSQTKSE TNWESPKQIK KKKKARRET
Length:579
Mass (Da):63,846
Last modified:June 1, 2003 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iE47E98303F588126
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
E9PUX0E9PUX0_MOUSE
Protein LYRIC
Mtdh
164Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F6ZSG0F6ZSG0_MOUSE
Protein LYRIC
Mtdh
356Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F6QHD1F6QHD1_MOUSE
Protein LYRIC
Mtdh
393Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F6ZQL0F6ZQL0_MOUSE
Protein LYRIC
Mtdh
220Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F6QFT1F6QFT1_MOUSE
Protein LYRIC
Mtdh
382Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A2I3BRF4A0A2I3BRF4_MOUSE
Protein LYRIC
Mtdh
91Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti190A → I in BAB27854 (PubMed:16141072).Curated1
Sequence conflicti264G → R in BAE30709 (PubMed:16141072).Curated1
Sequence conflicti271S → T in BAC26673 (PubMed:16141072).Curated1
Sequence conflicti296L → F in BAE30709 (PubMed:16141072).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

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DDBJi
Links Updated
AY553638 mRNA Translation: AAS68097.1
AF501309 mRNA Translation: AAP30790.1
AK011808 mRNA Translation: BAB27854.1
AK029915 mRNA Translation: BAC26673.1
AK035302 mRNA Translation: BAC29022.1
AK151269 mRNA Translation: BAE30256.1
AK151810 mRNA Translation: BAE30709.1
BC023115 mRNA Translation: AAH23115.1
BC036994 mRNA Translation: AAH36994.1
BC138858 mRNA Translation: AAI38859.1
BC138859 mRNA Translation: AAI38860.1

The Consensus CDS (CCDS) project

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CCDSi
CCDS27415.1

NCBI Reference Sequences

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RefSeqi
NP_080278.3, NM_026002.4

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000022865; ENSMUSP00000022865; ENSMUSG00000022255

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
67154

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:67154

UCSC genome browser

More...
UCSCi
uc007vlh.1 mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY553638 mRNA Translation: AAS68097.1
AF501309 mRNA Translation: AAP30790.1
AK011808 mRNA Translation: BAB27854.1
AK029915 mRNA Translation: BAC26673.1
AK035302 mRNA Translation: BAC29022.1
AK151269 mRNA Translation: BAE30256.1
AK151810 mRNA Translation: BAE30709.1
BC023115 mRNA Translation: AAH23115.1
BC036994 mRNA Translation: AAH36994.1
BC138858 mRNA Translation: AAI38859.1
BC138859 mRNA Translation: AAI38860.1
CCDSiCCDS27415.1
RefSeqiNP_080278.3, NM_026002.4

3D structure databases

SMRiQ80WJ7
ModBaseiSearch...

Protein-protein interaction databases

IntActiQ80WJ7, 8 interactors
MINTiQ80WJ7
STRINGi10090.ENSMUSP00000022865

PTM databases

iPTMnetiQ80WJ7
PhosphoSitePlusiQ80WJ7
SwissPalmiQ80WJ7

Proteomic databases

EPDiQ80WJ7
jPOSTiQ80WJ7
MaxQBiQ80WJ7
PaxDbiQ80WJ7
PeptideAtlasiQ80WJ7
PRIDEiQ80WJ7
TopDownProteomicsiQ80WJ7

Genome annotation databases

EnsembliENSMUST00000022865; ENSMUSP00000022865; ENSMUSG00000022255
GeneIDi67154
KEGGimmu:67154
UCSCiuc007vlh.1 mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
92140
MGIiMGI:1914404 Mtdh

Phylogenomic databases

eggNOGiENOG410IIV9 Eukaryota
ENOG410YF4D LUCA
GeneTreeiENSGT00940000154181
InParanoidiQ80WJ7
OMAiNYEEPPV
OrthoDBi1432988at2759
PhylomeDBiQ80WJ7
TreeFamiTF331350

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
Mtdh mouse

Protein Ontology

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PROi
PR:Q80WJ7

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000022255 Expressed in 286 organ(s), highest expression level in ear
ExpressionAtlasiQ80WJ7 baseline and differential
GenevisibleiQ80WJ7 MM

Family and domain databases

InterProiView protein in InterPro
IPR031402 LYRIC
PfamiView protein in Pfam
PF15686 LYRIC, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiLYRIC_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q80WJ7
Secondary accession number(s): B2RSG8
, Q05CM0, Q3U9F8, Q3UAQ8, Q8BN67, Q8CBT9, Q8CDL0, Q8CGI7, Q9D052
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 21, 2004
Last sequence update: June 1, 2003
Last modified: October 16, 2019
This is version 130 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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