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1 to 25 of 47  Show
  1. 1
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Category: Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is mapped to 1 other entry.

  2. 2
    "Defective prelamin A processing and muscular and adipocyte alterations in Zmpste24 metalloproteinase deficient mice."
    Pendas A.M., Zhou Z., Cadinanos J., Freije J.M.P., Wang J., Hultenby K., Astudillo A., Wernerson A., Rodriguez F., Triggvason K., Lopez-Otin C.
    Nat. Genet. 31:94-99(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA], FUNCTION IN LAMIN A/C PROCESSING.
    Category: Function, PTM / Processing, Sequences.
    Strain: C57BL/6J.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is mapped to 1 other entry.

  3. 3
    "The transcriptional landscape of the mammalian genome."
    Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
    Hayashizaki Y.
    Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Category: Sequences.
    Strain: C57BL/6J.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 10610 and mapped to 42946 other entries.

  4. 4
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Category: Sequences.
    Tissue: Heart, Kidney, Liver, Lung, Pancreas and Spleen.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 25319 other entries.

  5. 5
    "Zmpste24 deficiency in mice causes spontaneous bone fractures, muscle weakness, and a prelamin A processing defect."
    Bergo M.O., Gavino B., Ross J., Schmidt W.K., Hong C., Kendall L.V., Mohr A., Meta M., Genant H., Jiang Y., Wisner E.R., Van Bruggen N., Carano R.A., Michaelis S., Griffey S.M., Young S.G.
    Proc. Natl. Acad. Sci. U.S.A. 99:13049-13054(2002) [PubMed] [Europe PMC] [Abstract]
    Category: Pathology & Biotech.
    Annotation: Zmpste24 has a role in processing of prelamin A and lack of Zmpste24 results in a brittle bone phenotypeImported.
    Source: GeneRIF:230709, MGI:1890508.

    This publication is mapped to 15 other entries.

  6. 6
    "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
    Okazaki Y., Furuno M., Kasukawa T., Adachi J., Bono H., Kondo S., Nikaido I., Osato N., Saito R., Suzuki H., Yamanaka I., Kiyosawa H., Yagi K., Tomaru Y., Hasegawa Y., Nogami A., Schonbach C., Gojobori T.
    Hayashizaki Y.
    Nature 420:563-573(2002) [PubMed] [Europe PMC] [Abstract]
    Category: Sequences.
    Source: MGI:1890508.

    This publication is cited by 17016 and mapped to 40246 other entries.

  7. 7
    "Gene expression in mouse oocytes and preimplantation embryos: use of suppression subtractive hybridization to identify oocyte- and embryo-specific genes."
    Zeng F., Schultz R.M.
    Biol. Reprod. 68:31-39(2003) [PubMed] [Europe PMC] [Abstract]
    Category: Sequences.
    Source: MGI:1890508.

    This publication is mapped to 25 other entries.

  8. 8
    "BayGenomics: a resource of insertional mutations in mouse embryonic stem cells."
    Stryke D., Kawamoto M., Huang C.C., Johns S.J., King L.A., Harper C.A., Meng E.C., Lee R.E., Yee A., L'Italien L., Chuang P.T., Young S.G., Skarnes W.C., Babbitt P.C., Ferrin T.E.
    Nucleic Acids Res. 31:278-281(2003) [PubMed] [Europe PMC] [Abstract]
    Category: Sequences.
    Source: MGI:1890508.

    This publication is mapped to 18278 other entries.

  9. 9
    "Heterozygosity for Lmna deficiency eliminates the progeria-like phenotypes in Zmpste24-deficient mice."
    Fong L.G., Ng J.K., Meta M., Cote N., Yang S.H., Stewart C.L., Sullivan T., Burghardt A., Majumdar S., Reue K., Bergo M.O., Young S.G.
    Proc. Natl. Acad. Sci. U.S.A. 101:18111-18116(2004) [PubMed] [Europe PMC] [Abstract]
    Category: Pathology & Biotech.
    Annotation: the progeria-like phenotypes caused by the lack of Zmpste24 in knockout mice is eliminated by heterozygosity for LmnaImported.
    Source: GeneRIF:230709, MGI:1890508.

    This publication is mapped to 6 other entries.

  10. 10
    Category: Function, Pathology & Biotech.
    Annotation: Lack of functional Zmpste24 a metalloproteinase responsible for the maturation of prelamin A also results in progeroid phenotypes in miceImported.
    Source: GeneRIF:230709, MGI:1890508.

    This publication is mapped to 6 other entries.

  11. 11
    "Accelerated ageing in mice deficient in Zmpste24 protease is linked to p53 signalling activation."
    Varela I., Cadinanos J., Pendas A.M., Gutierrez-Fernandez A., Folgueras A.R., Sanchez L.M., Zhou Z., Rodriguez F.J., Stewart C.L., Vega J.A., Tryggvason K., Freije J.M., Lopez-Otin C.
    Nature 437:564-568(2005) [PubMed] [Europe PMC] [Abstract]
    Category: Function, Pathology & Biotech.
    Annotation: Zmpste24 deficiency elicits a stress signalling pathway that is evidenced by a marked upregulation of p53 target genes and accompanied by a senescence phenotype at the cellular level and accelerated ageing at the organismal levelImported.
    Source: GeneRIF:230709, MGI:1890508.

    This publication is mapped to 25 other entries.

  12. 12
    "A protein farnesyltransferase inhibitor ameliorates disease in a mouse model of progeria."
    Fong L.G., Frost D., Meta M., Qiao X., Yang S.H., Coffinier C., Young S.G.
    Science 311:1621-1623(2006) [PubMed] [Europe PMC] [Abstract]
    Category: Function, Pathology & Biotech.
    Source: MGI:1890508.

    This publication is mapped to 2 other entries.

  13. 13
    "Prelamin A and lamin A appear to be dispensable in the nuclear lamina."
    Fong L.G., Ng J.K., Lammerding J., Vickers T.A., Meta M., Cote N., Gavino B., Qiao X., Chang S.Y., Young S.R., Yang S.H., Stewart C.L., Lee R.T., Bennett C.F., Bergo M.O., Young S.G.
    J. Clin. Invest. 116:743-752(2006) [PubMed] [Europe PMC] [Abstract]
    Source: MGI:1890508.

    This publication is mapped to 5 other entries.

  14. 14
    "Global survey of organ and organelle protein expression in mouse: combined proteomic and transcriptomic profiling."
    Kislinger T., Cox B., Kannan A., Chung C., Hu P., Ignatchenko A., Scott M.S., Gramolini A.O., Morris Q., Hallett M.T., Rossant J., Hughes T.R., Frey B., Emili A.
    Cell 125:173-186(2006) [PubMed] [Europe PMC] [Abstract]
    Category: Interaction.
    Source: IntAct:Q80W54.

    This publication is mapped to 4104 other entries.

  15. 15
    "HIV protease inhibitors block the zinc metalloproteinase ZMPSTE24 and lead to an accumulation of prelamin A in cells."
    Coffinier C., Hudon S.E., Farber E.A., Chang S.Y., Hrycyna C.A., Young S.G., Fong L.G.
    Proc. Natl. Acad. Sci. U.S.A. 104:13432-13437(2007) [PubMed] [Europe PMC] [Abstract]
    Category: Function, PTM / Processing.
    Source: MGI:1890508.

    This publication is mapped to 2 other entries.

  16. 16
    "A potent HIV protease inhibitor, darunavir, does not inhibit ZMPSTE24 or lead to an accumulation of farnesyl-prelamin A in cells."
    Coffinier C., Hudon S.E., Lee R., Farber E.A., Nobumori C., Miner J.H., Andres D.A., Spielmann H.P., Hrycyna C.A., Fong L.G., Young S.G.
    J. Biol. Chem. 283:9797-9804(2008) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: darunavir does not inhibit the biochemical activity of ZMPSTE24 nor does it lead to an accumulation of farnesyl-prelamin A in cells.Imported.
    Source: GeneRIF:230709.

    This publication is mapped to 3 other entries.

  17. 17
    "Premature aging in mice activates a systemic metabolic response involving autophagy induction."
    Marino G., Ugalde A.P., Salvador-Montoliu N., Varela I., Quiros P.M., Cadinanos J., van der Pluijm I., Freije J.M., Lopez-Otin C.
    Hum. Mol. Genet. 17:2196-2211(2008) [PubMed] [Europe PMC] [Abstract]
    Category: Function, Pathology & Biotech.
    Annotation: Zmpste24-null mice show accelerated aging and exhibit an extensive basal activation of autophagy.Imported.
    Source: GeneRIF:230709, MGI:1890508.

    This publication is mapped to 31 other entries.

  18. 18
    "Combined treatment with statins and aminobisphosphonates extends longevity in a mouse model of human premature aging."
    Varela I., Pereira S., Ugalde A.P., Navarro C.L., Suarez M.F., Cau P., Cadinanos J., Osorio F.G., Foray N., Cobo J., de Carlos F., Levy N., Freije J.M., Lopez-Otin C.
    Nat. Med. 14:767-772(2008) [PubMed] [Europe PMC] [Abstract]
    Category: Function, Pathology & Biotech.
    Source: MGI:1890508.

    This publication is mapped to 2 other entries.

  19. 19
    "Genetic studies on the functional relevance of the protein prenyltransferases in skin keratinocytes."
    Lee R., Chang S.Y., Trinh H., Tu Y., White A.C., Davies B.S., Bergo M.O., Fong L.G., Lowry W.E., Young S.G.
    Hum. Mol. Genet. 19:1603-1617(2010) [PubMed] [Europe PMC] [Abstract]
    Category: Function, Pathology & Biotech.
    Source: MGI:1890508.

    This publication is mapped to 72 other entries.

  20. 20
    "Targeting the protein prenyltransferases efficiently reduces tumor development in mice with K-RAS-induced lung cancer."
    Liu M., Sjogren A.K., Karlsson C., Ibrahim M.X., Andersson K.M., Olofsson F.J., Wahlstrom A.M., Dalin M., Yu H., Chen Z., Yang S.H., Young S.G., Bergo M.O.
    Proc. Natl. Acad. Sci. U.S.A. 107:6471-6476(2010) [PubMed] [Europe PMC] [Abstract]
    Category: Function, Pathology & Biotech.
    Source: MGI:1890508.

    This publication is mapped to 19 other entries.

  21. 21
    "An accumulation of non-farnesylated prelamin A causes cardiomyopathy but not progeria."
    Davies B.S., Barnes R.H., Tu Y., Ren S., Andres D.A., Spielmann H.P., Lammerding J., Wang Y., Young S.G., Fong L.G.
    Hum. Mol. Genet. 19:2682-2694(2010) [PubMed] [Europe PMC] [Abstract]
    Category: Function, Pathology & Biotech.
    Source: MGI:1890508.

    This publication is mapped to 6 other entries.

  22. 22
    "Direct synthesis of lamin A, bypassing prelamin a processing, causes misshapen nuclei in fibroblasts but no detectable pathology in mice."
    Coffinier C., Jung H.J., Li Z., Nobumori C., Yun U.J., Farber E.A., Davies B.S., Weinstein M.M., Yang S.H., Lammerding J., Farahani J.N., Bentolila L.A., Fong L.G., Young S.G.
    J. Biol. Chem. 285:20818-20826(2010) [PubMed] [Europe PMC] [Abstract]
    Category: Subcellular Location.
    Source: MGI:1890508.

    This publication is mapped to 6 other entries.

  23. 23
    "Insulin-like growth factor 1 treatment extends longevity in a mouse model of human premature aging by restoring somatotroph axis function."
    Marino G., Ugalde A.P., Fernandez A.F., Osorio F.G., Fueyo A., Freije J.M., Lopez-Otin C.
    Proc. Natl. Acad. Sci. U.S.A. 107:16268-16273(2010) [PubMed] [Europe PMC] [Abstract]
    Category: Function, Pathology & Biotech.
    Source: MGI:1890508.

    This publication is mapped to 2 other entries.

  24. 24
    "Nuclear envelope alterations generate an aging-like epigenetic pattern in mice deficient in Zmpste24 metalloprotease."
    Osorio F.G., Varela I., Lara E., Puente X.S., Espada J., Santoro R., Freije J.M., Fraga M.F., Lopez-Otin C.
    Aging Cell 9:947-957(2010) [PubMed] [Europe PMC] [Abstract]
    Category: Function, Pathology & Biotech.
    Annotation: Nuclear envelope alterations generate an aging-like epigenetic pattern in mice deficient in Zmpste24 metalloproteaseImported.
    Source: GeneRIF:230709, MGI:1890508.

    This publication is mapped to 2 other entries.

  25. 25
    Category: Expression.
    Source: MGI:1890508.

    This publication is mapped to 49360 other entries.

1 to 25 of 47  Show
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