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Protein

CAAX prenyl protease 1 homolog

Gene

Zmpste24

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Proteolytically removes the C-terminal three residues of farnesylated proteins. Acts on lamin A/C.1 Publication

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

  • The peptide bond hydrolyzed can be designated -C-|-A-A-X in which C is an S-isoprenylated cysteine residue, A is usually aliphatic and X is the C-terminal residue of the substrate protein, and may be any of several amino acids. EC:3.4.24.84

<p>This subsection of the ‘Function’ section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

Zn2+By similarityNote: Binds 1 zinc ion per subunit.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Function’ section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the ‘Description’ field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi335Zinc; catalyticBy similarity1
<p>This subsection of the ‘Function’ section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei336By similarity1
Metal bindingi339Zinc; catalyticBy similarity1
Metal bindingi415Zinc; catalyticBy similarity1
Active sitei419Proton donorBy similarity1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • double-stranded DNA binding Source: MGI
  • endopeptidase activity Source: MGI
  • metal ion binding Source: UniProtKB-KW
  • metalloendopeptidase activity Source: MGI

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionHydrolase, Metalloprotease, Protease
LigandMetal-binding, Zinc

Enzyme and pathway databases

BRENDA Comprehensive Enzyme Information System

More...
BRENDAi
3.4.24.84 3474

Protein family/group databases

MEROPS protease database

More...
MEROPSi
M48.003

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
CAAX prenyl protease 1 homolog (EC:3.4.24.84)
Alternative name(s):
Farnesylated proteins-converting enzyme 1
Short name:
FACE-1
Prenyl protein-specific endoprotease 1
Zinc metalloproteinase Ste24 homolog
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Zmpste24
Synonyms:Face1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 4

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1890508 Zmpste24

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 18LumenalSequence analysisAdd BLAST18
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei19 – 39HelicalSequence analysisAdd BLAST21
Topological domaini40 – 81NuclearSequence analysisAdd BLAST42
Transmembranei82 – 102HelicalSequence analysisAdd BLAST21
Topological domaini103 – 123LumenalSequence analysisAdd BLAST21
Transmembranei124 – 144HelicalSequence analysisAdd BLAST21
Topological domaini145 – 170NuclearSequence analysisAdd BLAST26
Transmembranei171 – 191HelicalSequence analysisAdd BLAST21
Topological domaini192 – 195LumenalSequence analysis4
Transmembranei196 – 216HelicalSequence analysisAdd BLAST21
Topological domaini217 – 347NuclearSequence analysisAdd BLAST131
Transmembranei348 – 368HelicalSequence analysisAdd BLAST21
Topological domaini369 – 382LumenalSequence analysisAdd BLAST14
Transmembranei383 – 405HelicalSequence analysisAdd BLAST23
Topological domaini406 – 475NuclearSequence analysisAdd BLAST70

Keywords - Cellular componenti

Endoplasmic reticulum, Membrane, Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Chemistry databases

ChEMBL database of bioactive drug-like small molecules

More...
ChEMBLi
CHEMBL1075286

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001388451 – 475CAAX prenyl protease 1 homologAdd BLAST475

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q80W54

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q80W54

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q80W54

PRoteomics IDEntifications database

More...
PRIDEi
Q80W54

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q80W54

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q80W54

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
Q80W54

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000043207 Expressed in 274 organ(s), highest expression level in cleaving embryo

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q80W54 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q80W54 MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

Protein interaction database and analysis system

More...
IntActi
Q80W54, 2 interactors

Molecular INTeraction database

More...
MINTi
Q80W54

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000053900

Chemistry databases

BindingDB database of measured binding affinities

More...
BindingDBi
Q80W54

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
Q80W54

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q80W54

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides general information on the biological role of a domain. The term ‘domain’ is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

The metalloprotease domain is constituted by the two C-terminal nuclear regions.By similarity

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the peptidase M48A family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2719 Eukaryota
COG0501 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000002053

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000257874

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG051541

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q80W54

KEGG Orthology (KO)

More...
KOi
K06013

Identification of Orthologs from Complete Genome Data

More...
OMAi
RFEYQAD

Database of Orthologous Groups

More...
OrthoDBi
EOG091G074G

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q80W54

TreeFam database of animal gene trees

More...
TreeFami
TF105972

Family and domain databases

Conserved Domains Database

More...
CDDi
cd07343 M48A_Zmpste24p_like, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR027057 CAXX_Prtase_1
IPR001915 Peptidase_M48
IPR032456 Peptidase_M48_N

The PANTHER Classification System

More...
PANTHERi
PTHR10120 PTHR10120, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01435 Peptidase_M48, 1 hit
PF16491 Peptidase_M48_N, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q80W54-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGMWASVDAM WDFPAEKRIF GAVLLFSWTV YLWETFLAQR QRRIYKTTTR
60 70 80 90 100
VPAELEQIMD SDTFEKSRLY QLDKSTFSFW SGLYSEVEGT FILLFGGIPY
110 120 130 140 150
LWRLSGQFCS SAGFGPEYEI IQSLVFLLLA TLFSALTGLP WSLYNTFVIE
160 170 180 190 200
EKHGFNHQTL EFFMKDAIKK FIVTQCILLP VSALLLYIIK IGGDYFFIYA
210 220 230 240 250
WLFTLVVSLV LVTIYADYIA PLFDKFTPLP EGKLKQEIEV MAKSIDFPLT
260 270 280 290 300
KVYVVEGSKR SSHSNAYFYG FFKNKRIVLF DTLLEEYSVP NKDNQEESGM
310 320 330 340 350
EARNEGEGDS EEVKAKVKNK KQGCKNEEVL AVLGHELGHW KLGHTVKNII
360 370 380 390 400
ISQMNSFLCF FLFAVLIGRR ELFAAFGFYD SQPTLIGLLI IFQFIFSPYN
410 420 430 440 450
EVLSFCLTVL SRRFEFQADA FAKKLGKAKD LYSALIKLNK DNLGFPVSDW
460 470
LFSTWHYSHP PLLERLQALK NAKQD
Length:475
Mass (Da):54,735
Last modified:September 13, 2005 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i509B82D757FC7A4B
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
I7HIP5I7HIP5_MOUSE
CAAX prenyl protease 1 homolog
Zmpste24
146Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti53A → S in CAD31792 (PubMed:11923874).Curated1
Sequence conflicti153H → Q in AAK38172 (PubMed:11399759).Curated1
Sequence conflicti157H → Q in AAK38172 (PubMed:11399759).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AY029194 mRNA Translation: AAK38172.1
AJ487544 mRNA Translation: CAD31792.1
AK083566 mRNA Translation: BAC38953.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS18600.1

NCBI Reference Sequences

More...
RefSeqi
NP_766288.1, NM_172700.2

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Mm.34399

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000058754; ENSMUSP00000053900; ENSMUSG00000043207

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
230709

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:230709

UCSC genome browser

More...
UCSCi
uc008uny.1 mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY029194 mRNA Translation: AAK38172.1
AJ487544 mRNA Translation: CAD31792.1
AK083566 mRNA Translation: BAC38953.1
CCDSiCCDS18600.1
RefSeqiNP_766288.1, NM_172700.2
UniGeneiMm.34399

3D structure databases

ProteinModelPortaliQ80W54
SMRiQ80W54
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ80W54, 2 interactors
MINTiQ80W54
STRINGi10090.ENSMUSP00000053900

Chemistry databases

BindingDBiQ80W54
ChEMBLiCHEMBL1075286

Protein family/group databases

MEROPSiM48.003

PTM databases

iPTMnetiQ80W54
PhosphoSitePlusiQ80W54
SwissPalmiQ80W54

Proteomic databases

EPDiQ80W54
MaxQBiQ80W54
PaxDbiQ80W54
PRIDEiQ80W54

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000058754; ENSMUSP00000053900; ENSMUSG00000043207
GeneIDi230709
KEGGimmu:230709
UCSCiuc008uny.1 mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
10269
MGIiMGI:1890508 Zmpste24

Phylogenomic databases

eggNOGiKOG2719 Eukaryota
COG0501 LUCA
GeneTreeiENSGT00390000002053
HOGENOMiHOG000257874
HOVERGENiHBG051541
InParanoidiQ80W54
KOiK06013
OMAiRFEYQAD
OrthoDBiEOG091G074G
PhylomeDBiQ80W54
TreeFamiTF105972

Enzyme and pathway databases

BRENDAi3.4.24.84 3474

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q80W54

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000043207 Expressed in 274 organ(s), highest expression level in cleaving embryo
ExpressionAtlasiQ80W54 baseline and differential
GenevisibleiQ80W54 MM

Family and domain databases

CDDicd07343 M48A_Zmpste24p_like, 1 hit
InterProiView protein in InterPro
IPR027057 CAXX_Prtase_1
IPR001915 Peptidase_M48
IPR032456 Peptidase_M48_N
PANTHERiPTHR10120 PTHR10120, 1 hit
PfamiView protein in Pfam
PF01435 Peptidase_M48, 1 hit
PF16491 Peptidase_M48_N, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiFACE1_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q80W54
Secondary accession number(s): Q8BJK4, Q8K569
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 13, 2005
Last sequence update: September 13, 2005
Last modified: December 5, 2018
This is version 116 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Peptidase families
    Classification of peptidase families and list of entries
  3. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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