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UniProtKB - Q80VQ1 (LRRC1_MOUSE)

Entry version 143 (29 Sep 2021)
Sequence version 2 (19 Jul 2004)
Previous versions | rss
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Protein

Leucine-rich repeat-containing protein 1

Gene

Lrrc1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...Reactomei		R-MMU-9696270, RND2 GTPase cycle

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Leucine-rich repeat-containing protein 1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Lrrc1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 9

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...MGIi		MGI:2442313, Lrrc1

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSMUSG00000032352

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cytoplasm, Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000844901 – 524Leucine-rich repeat-containing protein 1Add BLAST524

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei480PhosphothreonineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		Q80VQ1

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q80VQ1

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q80VQ1

PeptideAtlas

More...PeptideAtlasi		Q80VQ1

PRoteomics IDEntifications database

More...PRIDEi		Q80VQ1

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		292365 [Q80VQ1-1]
292366 [Q80VQ1-2]
292367 [Q80VQ1-3]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q80VQ1

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q80VQ1

SwissPalm database of S-palmitoylation events

More...SwissPalmi		Q80VQ1

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSMUSG00000032352, Expressed in spermatid and 258 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q80VQ1, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q80VQ1, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with DLG1. May form a complex with DLG1 and ERBIN, where interaction between LRRC1 and ERBIN is indirect (By similarity).

By similarity

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		229517, 1 interactor

Protein interaction database and analysis system

More...IntActi		Q80VQ1, 1 interactor

STRING: functional protein association networks

More...STRINGi		10090.ENSMUSP00000109048

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q80VQ1, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q80VQ1

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati11 – 34LRR 1Add BLAST24
Repeati35 – 58LRR 2Add BLAST24
Repeati60 – 81LRR 3Add BLAST22
Repeati83 – 105LRR 4Add BLAST23
Repeati107 – 126LRR 5Add BLAST20
Repeati127 – 149LRR 6Add BLAST23
Repeati150 – 172LRR 7Add BLAST23
Repeati173 – 196LRR 8Add BLAST24
Repeati198 – 218LRR 9Add BLAST21
Repeati219 – 242LRR 10Add BLAST24
Repeati244 – 264LRR 11Add BLAST21
Repeati265 – 288LRR 12Add BLAST24
Repeati290 – 310LRR 13Add BLAST21
Repeati311 – 334LRR 14Add BLAST24
Repeati336 – 356LRR 15Add BLAST21
Repeati357 – 380LRR 16Add BLAST24
Repeati382 – 405LRR 17Add BLAST24

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni464 – 485DisorderedSequence analysisAdd BLAST22

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili456 – 512Sequence analysisAdd BLAST57

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi470 – 485Basic and acidic residuesSequence analysisAdd BLAST16

Keywords - Domaini

Coiled coil, Leucine-rich repeat, Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG0619, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00940000154025

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_000288_18_23_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q80VQ1

Identification of Orthologs from Complete Genome Data

More...OMAi		VHLKDLW

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q80VQ1

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		3.80.10.10, 3 hits

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR001611, Leu-rich_rpt
IPR003591, Leu-rich_rpt_typical-subtyp
IPR032675, LRR_dom_sf

Pfam protein domain database

More...Pfami		View protein in Pfam
PF13855, LRR_8, 3 hits

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00369, LRR_TYP, 12 hits

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS51450, LRR, 15 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q80VQ1-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MFHCIPLWRC NRHVEAIDKR HCSLVYVPEE IYRYARSLEE LLLDANQLRE 
        60         70         80         90        100
LPEQFFQLVK LRKLGLSDNE IQRLPPEIAN FMQLVELDVS RNDIPEIPES 
       110        120        130        140        150
IAFCKALQVA DFSGNPLTRL PESFPELQNL TCLSVNDISL QSLPENIGNL 
       160        170        180        190        200
YNLASLELRE NLLTYLPDSL TQLRRLEELD LGNNEIYNLP ESIGALLHLK 
       210        220        230        240        250
DLWLDGNQLS ELPQEIGNLK NLLCLDVSEN RLERLPEEIS GLTSLTYLVI 
       260        270        280        290        300
SQNLLETIPE GIGKLKKLSI LKLDQNRLTQ LPEAIGDCEN LTELVLTENR 
       310        320        330        340        350
LLTLPKSIGK LKKLSNLNAD RNKLVSLPKE IGGCCSLTMF CIRDNRLTRL 
       360        370        380        390        400
PAEVSQAVEL HVLDVAGNRL HHLPLSLTTL KLKALWLSDN QSQPLLTFQT 
       410        420        430        440        450
DIDRATGEKI LTCVLLPQMP SEPICQESLP RCGALESLVT DMSEEAWNDR 
       460        470        480        490        500
SVHRVSAIRF LEDEKDEDEN ETRTLQRRAT PHPGELKNMK KTVENLRNDM 
       510        520 
NAAKGLDSNK NEVNHAAERV TTSV
Length:524
Mass (Da):59,412
Last modified:July 19, 2004 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i546AA6726A1109D8
GO
Isoform 2 (identifier: Q80VQ1-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-81: Missing.

Show »
Length:443
Mass (Da):49,664
Checksum:iAB413EB34B04EF01
GO
Isoform 3 (identifier: Q80VQ1-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     331-349: IGGCCSLTMFCIRDNRLTR → EHISGKVCRLFYHKAATAI
     350-524: Missing.

Show »
Length:349
Mass (Da):39,788
Checksum:iE2C0177B26A57554
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
G3X9W3G3X9W3_MOUSE
Leucine-rich repeat-containing prot...
Lrrc1
479Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
V9GX13V9GX13_MOUSE
Leucine-rich repeat-containing prot...
Lrrc1
63Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAH46591 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti115N → D in BAC38586 (PubMed:16141072).Curated1
Sequence conflicti369R → K in BAC34508 (PubMed:16141072).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0109141 – 81Missing in isoform 2. 1 PublicationAdd BLAST81
Alternative sequenceiVSP_010915331 – 349IGGCC…NRLTR → EHISGKVCRLFYHKAATAI in isoform 3. 1 PublicationAdd BLAST19
Alternative sequenceiVSP_010916350 – 524Missing in isoform 3. 1 PublicationAdd BLAST175

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AK051043 mRNA Translation: BAC34508.1
AK082721 mRNA Translation: BAC38586.1
AK147075 mRNA Translation: BAE27656.1
BC046591 mRNA Translation: AAH46591.1 Different initiation.
BC087542 mRNA Translation: AAH87542.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS72282.1 [Q80VQ1-1]

NCBI Reference Sequences

More...RefSeqi		NP_001139520.1, NM_001146048.1 [Q80VQ1-1]
NP_766116.3, NM_172528.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENSMUST00000183734; ENSMUSP00000138912; ENSMUSG00000032352 [Q80VQ1-3]
ENSMUST00000183873; ENSMUSP00000139226; ENSMUSG00000032352 [Q80VQ1-1]

Database of genes from NCBI RefSeq genomes

More...GeneIDi		214345

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		mmu:214345

UCSC genome browser

More...UCSCi		uc009qtk.2, mouse [Q80VQ1-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK051043 mRNA Translation: BAC34508.1
AK082721 mRNA Translation: BAC38586.1
AK147075 mRNA Translation: BAE27656.1
BC046591 mRNA Translation: AAH46591.1 Different initiation.
BC087542 mRNA Translation: AAH87542.1
CCDSiCCDS72282.1 [Q80VQ1-1]
RefSeqiNP_001139520.1, NM_001146048.1 [Q80VQ1-1]
NP_766116.3, NM_172528.3

3D structure databases

SMRiQ80VQ1
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi229517, 1 interactor
IntActiQ80VQ1, 1 interactor
STRINGi10090.ENSMUSP00000109048

PTM databases

iPTMnetiQ80VQ1
PhosphoSitePlusiQ80VQ1
SwissPalmiQ80VQ1

Proteomic databases

EPDiQ80VQ1
jPOSTiQ80VQ1
PaxDbiQ80VQ1
PeptideAtlasiQ80VQ1
PRIDEiQ80VQ1
ProteomicsDBi292365 [Q80VQ1-1]
292366 [Q80VQ1-2]
292367 [Q80VQ1-3]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		17278, 93 antibodies

The DNASU plasmid repository

More...DNASUi		214345

Genome annotation databases

EnsembliENSMUST00000183734; ENSMUSP00000138912; ENSMUSG00000032352 [Q80VQ1-3]
ENSMUST00000183873; ENSMUSP00000139226; ENSMUSG00000032352 [Q80VQ1-1]
GeneIDi214345
KEGGimmu:214345
UCSCiuc009qtk.2, mouse [Q80VQ1-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		55227
MGIiMGI:2442313, Lrrc1
VEuPathDBiHostDB:ENSMUSG00000032352

Phylogenomic databases

eggNOGiKOG0619, Eukaryota
GeneTreeiENSGT00940000154025
HOGENOMiCLU_000288_18_23_1
InParanoidiQ80VQ1
OMAiVHLKDLW
PhylomeDBiQ80VQ1

Enzyme and pathway databases

ReactomeiR-MMU-9696270, RND2 GTPase cycle

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		214345, 0 hits in 61 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		Lrrc1, mouse

Protein Ontology

More...PROi		PR:Q80VQ1
RNActiQ80VQ1, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSMUSG00000032352, Expressed in spermatid and 258 other tissues
ExpressionAtlasiQ80VQ1, baseline and differential
GenevisibleiQ80VQ1, MM

Family and domain databases

Gene3Di3.80.10.10, 3 hits
InterProiView protein in InterPro
IPR001611, Leu-rich_rpt
IPR003591, Leu-rich_rpt_typical-subtyp
IPR032675, LRR_dom_sf
PfamiView protein in Pfam
PF13855, LRR_8, 3 hits
SMARTiView protein in SMART
SM00369, LRR_TYP, 12 hits
PROSITEiView protein in PROSITE
PS51450, LRR, 15 hits

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiLRRC1_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q80VQ1
Secondary accession number(s): Q3UI50, Q8BKR1, Q8BUS9
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 19, 2004
Last sequence update: July 19, 2004
Last modified: September 29, 2021
This is version 143 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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