UniProtKB - Q80VD1 (FA98B_MOUSE)
Protein
Protein FAM98B
Gene
Fam98b
Organism
Mus musculus (Mouse)
Status
Functioni
Positively stimulates PRMT1-induced protein arginine dimethylated arginine methylation.By similarity
GO - Molecular functioni
- identical protein binding Source: UniProtKB
- protein methyltransferase activity Source: UniProtKB
GO - Biological processi
- positive regulation of cell population proliferation Source: UniProtKB
- positive regulation of gene expression Source: UniProtKB
- protein methylation Source: UniProtKB
Names & Taxonomyi
Protein namesi | Recommended name: Protein FAM98B |
Gene namesi | Name:Fam98b |
Organismi | Mus musculus (Mouse) |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Proteomesi |
|
Organism-specific databases
MGIi | MGI:1915465, Fam98b |
Subcellular locationi
Nucleus
- nucleoplasm Source: MGI
- nucleus Source: UniProtKB
Other locations
- cytoplasm Source: UniProtKB
- intracellular membrane-bounded organelle Source: MGI
- tRNA-splicing ligase complex Source: UniProtKB
Keywords - Cellular componenti
Cytoplasm, NucleusPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000187189 | 1 – 429 | Protein FAM98BAdd BLAST | 429 |
Proteomic databases
EPDi | Q80VD1 |
jPOSTi | Q80VD1 |
MaxQBi | Q80VD1 |
PaxDbi | Q80VD1 |
PeptideAtlasi | Q80VD1 |
PRIDEi | Q80VD1 |
PTM databases
iPTMneti | Q80VD1 |
PhosphoSitePlusi | Q80VD1 |
Expressioni
Gene expression databases
Bgeei | ENSMUSG00000027349, Expressed in pes and 254 other tissues |
Genevisiblei | Q80VD1, MM |
Interactioni
Subunit structurei
Homodimer.
Component of a tRNA-splicing ligase complex.
Interacts with FAM98A.
By similarityGO - Molecular functioni
- identical protein binding Source: UniProtKB
Protein-protein interaction databases
BioGRIDi | 212735, 10 interactors |
IntActi | Q80VD1, 3 interactors |
MINTi | Q80VD1 |
STRINGi | 10090.ENSMUSP00000028825 |
Miscellaneous databases
RNActi | Q80VD1, protein |
Family & Domainsi
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 317 – 320 | Poly-Pro | 4 | |
Compositional biasi | 331 – 425 | Gly-richAdd BLAST | 95 |
Sequence similaritiesi
Belongs to the FAM98 family.Curated
Phylogenomic databases
eggNOGi | KOG3973, Eukaryota |
GeneTreei | ENSGT00440000037341 |
HOGENOMi | CLU_038408_1_0_1 |
InParanoidi | Q80VD1 |
OMAi | NDQQWIS |
OrthoDBi | 800008at2759 |
PhylomeDBi | Q80VD1 |
TreeFami | TF320308 |
Family and domain databases
InterProi | View protein in InterPro IPR018797, FAM98 |
PANTHERi | PTHR31353, PTHR31353, 1 hit |
Pfami | View protein in Pfam PF10239, DUF2465, 1 hit |
i Sequence
Sequence statusi: Complete.
Q80VD1-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MRGPELGPET SMEGDVLDTL EALGYKGPLL EEQALSKAAE GGLSSPEFSE
60 70 80 90 100
LCIWLGSQIK SLCNLEESIT SAGRDDLESF QLEISGFLKE MACPYSVLVS
110 120 130 140 150
GDIKERLTKK DDCLKLLLFL STELQALQIL QKKKHKNSQL DKNSEICQEV
160 170 180 190 200
QAVCDALGVP KSDTSDIPLL LSQVESKVKD ILCRVQKNHV GKPLLKVDLS
210 220 230 240 250
SEQAEKLERI NDALSCEYEC RRRMLMKRLD VTVQSFGWSD RAKAKTDNIA
260 270 280 290 300
RIYQPKRYAL SPKTTVTLAH LLAAREDLSK IIRTSSGISR EKTACAINKV
310 320 330 340 350
LMGRVPDRGG RPNEIEPPPP EMPPWQKRQE GGGRGGWGGG GGGRGGGGGG
360 370 380 390 400
RGGWGGGGGW GGGGGSGGGW GGSGGGGGGR GGFQGRGDYG GRGDYGGRGG
410 420
YGGRGGYGGR GYGDPYGGGG GGGGGYRRY
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL928959 Genomic DNA No translation available. BC048087 mRNA Translation: AAH48087.1 AK019190 mRNA Translation: BAB31594.1 AK019253 mRNA Translation: BAB31629.1 |
CCDSi | CCDS16571.1 |
RefSeqi | NP_080896.2, NM_026620.3 |
Genome annotation databases
Ensembli | ENSMUST00000028825; ENSMUSP00000028825; ENSMUSG00000027349 |
GeneIDi | 68215 |
KEGGi | mmu:68215 |
UCSCi | uc008lrk.1, mouse |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL928959 Genomic DNA No translation available. BC048087 mRNA Translation: AAH48087.1 AK019190 mRNA Translation: BAB31594.1 AK019253 mRNA Translation: BAB31629.1 |
CCDSi | CCDS16571.1 |
RefSeqi | NP_080896.2, NM_026620.3 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
BioGRIDi | 212735, 10 interactors |
IntActi | Q80VD1, 3 interactors |
MINTi | Q80VD1 |
STRINGi | 10090.ENSMUSP00000028825 |
PTM databases
iPTMneti | Q80VD1 |
PhosphoSitePlusi | Q80VD1 |
Proteomic databases
EPDi | Q80VD1 |
jPOSTi | Q80VD1 |
MaxQBi | Q80VD1 |
PaxDbi | Q80VD1 |
PeptideAtlasi | Q80VD1 |
PRIDEi | Q80VD1 |
Protocols and materials databases
Antibodypediai | 2032, 101 antibodies |
Genome annotation databases
Ensembli | ENSMUST00000028825; ENSMUSP00000028825; ENSMUSG00000027349 |
GeneIDi | 68215 |
KEGGi | mmu:68215 |
UCSCi | uc008lrk.1, mouse |
Organism-specific databases
CTDi | 283742 |
MGIi | MGI:1915465, Fam98b |
Phylogenomic databases
eggNOGi | KOG3973, Eukaryota |
GeneTreei | ENSGT00440000037341 |
HOGENOMi | CLU_038408_1_0_1 |
InParanoidi | Q80VD1 |
OMAi | NDQQWIS |
OrthoDBi | 800008at2759 |
PhylomeDBi | Q80VD1 |
TreeFami | TF320308 |
Miscellaneous databases
BioGRID-ORCSi | 68215, 1 hit in 17 CRISPR screens |
PROi | PR:Q80VD1 |
RNActi | Q80VD1, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSMUSG00000027349, Expressed in pes and 254 other tissues |
Genevisiblei | Q80VD1, MM |
Family and domain databases
InterProi | View protein in InterPro IPR018797, FAM98 |
PANTHERi | PTHR31353, PTHR31353, 1 hit |
Pfami | View protein in Pfam PF10239, DUF2465, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | FA98B_MOUSE | |
Accessioni | Q80VD1Primary (citable) accession number: Q80VD1 Secondary accession number(s): A2ATZ4, Q9CS28, Q9CS37 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | December 6, 2005 |
Last sequence update: | June 1, 2003 | |
Last modified: | December 2, 2020 | |
This is version 114 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- MGD cross-references
Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot - SIMILARITY comments
Index of protein domains and families