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UniProtKB - Q80V23 (ZNF32_MOUSE)
Protein
Zinc finger protein 32
Gene
Znf32
Organism
Mus musculus (Mouse)
Status
Functioni
May be involved in transcriptional regulation.
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Zinc fingeri | 76 – 98 | C2H2-type 1PROSITE-ProRule annotationAdd BLAST | 23 | |
Zinc fingeri | 104 – 126 | C2H2-type 2PROSITE-ProRule annotationAdd BLAST | 23 | |
Zinc fingeri | 132 – 154 | C2H2-type 3PROSITE-ProRule annotationAdd BLAST | 23 | |
Zinc fingeri | 160 – 182 | C2H2-type 4PROSITE-ProRule annotationAdd BLAST | 23 | |
Zinc fingeri | 188 – 210 | C2H2-type 5PROSITE-ProRule annotationAdd BLAST | 23 | |
Zinc fingeri | 216 – 238 | C2H2-type 6PROSITE-ProRule annotationAdd BLAST | 23 | |
Zinc fingeri | 244 – 265 | C2H2-type 7; degeneratePROSITE-ProRule annotationAdd BLAST | 22 |
GO - Molecular functioni
- DNA-binding transcription factor activity, RNA polymerase II-specific Source: GO_Central
- metal ion binding Source: UniProtKB-KW
- RNA polymerase II cis-regulatory region sequence-specific DNA binding Source: GO_Central
- sequence-specific double-stranded DNA binding Source: MGI
GO - Biological processi
- regulation of transcription by RNA polymerase II Source: GO_Central
Keywordsi
Ligand | Metal-binding, Zinc |
Names & Taxonomyi
Protein namesi | Recommended name: Zinc finger protein 32Alternative name(s): Zinc finger protein 637 |
Gene namesi | Name:Znf32 Synonyms:Zfp637 |
Organismi | Mus musculus (Mouse) |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Proteomesi |
|
Organism-specific databases
MGIi | MGI:2448537, Zfp637 |
VEuPathDBi | HostDB:ENSMUSG00000059689 |
Subcellular locationi
Nucleus
- Nucleus Curated
Nucleus
- nucleus Source: UniProtKB-SubCell
Keywords - Cellular componenti
NucleusPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000047362 | 1 – 272 | Zinc finger protein 32Add BLAST | 272 |
Proteomic databases
MaxQBi | Q80V23 |
PaxDbi | Q80V23 |
PRIDEi | Q80V23 |
ProteomicsDBi | 275303 [Q80V23-1] 275304 [Q80V23-2] |
PTM databases
iPTMneti | Q80V23 |
PhosphoSitePlusi | Q80V23 |
Expressioni
Gene expression databases
Bgeei | ENSMUSG00000059689, Expressed in limb and 284 other tissues |
ExpressionAtlasi | Q80V23, baseline and differential |
Genevisiblei | Q80V23, MM |
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 50 – 69 | DisorderedSequence analysisAdd BLAST | 20 |
Sequence similaritiesi
Belongs to the krueppel C2H2-type zinc-finger protein family.Curated
Zinc finger
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Zinc fingeri | 76 – 98 | C2H2-type 1PROSITE-ProRule annotationAdd BLAST | 23 | |
Zinc fingeri | 104 – 126 | C2H2-type 2PROSITE-ProRule annotationAdd BLAST | 23 | |
Zinc fingeri | 132 – 154 | C2H2-type 3PROSITE-ProRule annotationAdd BLAST | 23 | |
Zinc fingeri | 160 – 182 | C2H2-type 4PROSITE-ProRule annotationAdd BLAST | 23 | |
Zinc fingeri | 188 – 210 | C2H2-type 5PROSITE-ProRule annotationAdd BLAST | 23 | |
Zinc fingeri | 216 – 238 | C2H2-type 6PROSITE-ProRule annotationAdd BLAST | 23 | |
Zinc fingeri | 244 – 265 | C2H2-type 7; degeneratePROSITE-ProRule annotationAdd BLAST | 22 |
Keywords - Domaini
Repeat, Zinc-fingerPhylogenomic databases
eggNOGi | KOG1721, Eukaryota |
GeneTreei | ENSGT00940000153582 |
HOGENOMi | CLU_002678_18_0_1 |
InParanoidi | Q80V23 |
OMAi | NCVLHGK |
OrthoDBi | 1318335at2759 |
PhylomeDBi | Q80V23 |
TreeFami | TF337055 |
Family and domain databases
InterProi | View protein in InterPro IPR036236, Znf_C2H2_sf IPR013087, Znf_C2H2_type |
Pfami | View protein in Pfam PF00096, zf-C2H2, 6 hits |
SMARTi | View protein in SMART SM00355, ZnF_C2H2, 7 hits |
SUPFAMi | SSF57667, SSF57667, 4 hits |
PROSITEi | View protein in PROSITE PS00028, ZINC_FINGER_C2H2_1, 6 hits PS50157, ZINC_FINGER_C2H2_2, 7 hits |
s (2+)i Sequence
Sequence statusi: Complete.
This entry describes 2 produced by isoformsialternative splicing. AlignAdd to basketThis entry has 2 described isoforms and 3 potential isoforms that are computationally mapped.Show allAlign All
Isoform 1 (identifier: Q80V23-1) [UniParc]FASTAAdd to basket
This isoform has been chosen as the sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. canonicali
10 20 30 40 50
MFGFPTATLL DCHGRYAQNV AFFNVMTEAH KYDPSEATGS SSWDFQSSFR
60 70 80 90 100
REKLEQKSPE SKALQEDSPG VRQKVYDCQE CGKSFRQKGS LTLHERIHTG
110 120 130 140 150
QKPFECTQCG KSFRAKGNLV THQRIHTGEK PYQCKECGKS FSQRGSLAVH
160 170 180 190 200
ERLHTGQKPY ECAICQRSFR NQSNLAVHRR VHSGEKPYRC DQCGKAFSQK
210 220 230 240 250
GSLIVHIRVH TGLKPYACSH CRKSFHTRGN CLLHGKVHTG ETPYLCGQCG
260 270
KSFTQRGSLA VHQRSCSQRL TL
Computationally mapped potential isoform sequencesi
There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketD3YYX3 | D3YYX3_MOUSE | Zinc finger protein 637 | Zfp637 | 153 | Annotation score: | ||
D3Z0E5 | D3Z0E5_MOUSE | Zinc finger protein 637 | Zfp637 | 202 | Annotation score: | ||
D3Z3T2 | D3Z3T2_MOUSE | Zinc finger protein 637 | Zfp637 | 33 | Annotation score: |
Alternative sequence
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Alternative sequenceiVSP_016954 | 23 – 24 | FN → FTYWCILHDFPLVLPD in isoform 2. 1 Publication | 2 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK146789 mRNA Translation: BAE27433.1 BC048843 mRNA Translation: AAH48843.1 |
CCDSi | CCDS39607.1 [Q80V23-1] CCDS85139.1 [Q80V23-2] |
RefSeqi | NP_001333576.1, NM_001346647.1 [Q80V23-2] NP_001333577.1, NM_001346648.1 [Q80V23-2] NP_001333578.1, NM_001346649.1 [Q80V23-1] NP_001333579.1, NM_001346650.1 [Q80V23-1] NP_001333580.1, NM_001346651.1 NP_001333581.1, NM_001346652.1 NP_001333582.1, NM_001346653.1 NP_808352.1, NM_177684.3 [Q80V23-1] XP_006506080.1, XM_006506017.3 [Q80V23-2] |
Genome annotation databases
Ensembli | ENSMUST00000112860; ENSMUSP00000108481; ENSMUSG00000059689 [Q80V23-2] ENSMUST00000112861; ENSMUSP00000108482; ENSMUSG00000059689 [Q80V23-1] ENSMUST00000164472; ENSMUSP00000130144; ENSMUSG00000059689 [Q80V23-1] ENSMUST00000223041; ENSMUSP00000152569; ENSMUSG00000059689 [Q80V23-2] |
GeneIDi | 232337 |
KEGGi | mmu:232337 |
UCSCi | uc009dky.1, mouse [Q80V23-1] uc009dkz.1, mouse [Q80V23-2] |
Keywords - Coding sequence diversityi
Alternative splicingSimilar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK146789 mRNA Translation: BAE27433.1 BC048843 mRNA Translation: AAH48843.1 |
CCDSi | CCDS39607.1 [Q80V23-1] CCDS85139.1 [Q80V23-2] |
RefSeqi | NP_001333576.1, NM_001346647.1 [Q80V23-2] NP_001333577.1, NM_001346648.1 [Q80V23-2] NP_001333578.1, NM_001346649.1 [Q80V23-1] NP_001333579.1, NM_001346650.1 [Q80V23-1] NP_001333580.1, NM_001346651.1 NP_001333581.1, NM_001346652.1 NP_001333582.1, NM_001346653.1 NP_808352.1, NM_177684.3 [Q80V23-1] XP_006506080.1, XM_006506017.3 [Q80V23-2] |
3D structure databases
SMRi | Q80V23 |
ModBasei | Search... |
PTM databases
iPTMneti | Q80V23 |
PhosphoSitePlusi | Q80V23 |
Proteomic databases
MaxQBi | Q80V23 |
PaxDbi | Q80V23 |
PRIDEi | Q80V23 |
ProteomicsDBi | 275303 [Q80V23-1] 275304 [Q80V23-2] |
Protocols and materials databases
Antibodypediai | 26938, 64 antibodies from 13 providers |
DNASUi | 232337 |
Genome annotation databases
Ensembli | ENSMUST00000112860; ENSMUSP00000108481; ENSMUSG00000059689 [Q80V23-2] ENSMUST00000112861; ENSMUSP00000108482; ENSMUSG00000059689 [Q80V23-1] ENSMUST00000164472; ENSMUSP00000130144; ENSMUSG00000059689 [Q80V23-1] ENSMUST00000223041; ENSMUSP00000152569; ENSMUSG00000059689 [Q80V23-2] |
GeneIDi | 232337 |
KEGGi | mmu:232337 |
UCSCi | uc009dky.1, mouse [Q80V23-1] uc009dkz.1, mouse [Q80V23-2] |
Organism-specific databases
CTDi | 232337 |
MGIi | MGI:2448537, Zfp637 |
VEuPathDBi | HostDB:ENSMUSG00000059689 |
Phylogenomic databases
eggNOGi | KOG1721, Eukaryota |
GeneTreei | ENSGT00940000153582 |
HOGENOMi | CLU_002678_18_0_1 |
InParanoidi | Q80V23 |
OMAi | NCVLHGK |
OrthoDBi | 1318335at2759 |
PhylomeDBi | Q80V23 |
TreeFami | TF337055 |
Miscellaneous databases
BioGRID-ORCSi | 232337, 0 hits in 63 CRISPR screens |
ChiTaRSi | Zfp637, mouse |
PROi | PR:Q80V23 |
RNActi | Q80V23, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSMUSG00000059689, Expressed in limb and 284 other tissues |
ExpressionAtlasi | Q80V23, baseline and differential |
Genevisiblei | Q80V23, MM |
Family and domain databases
InterProi | View protein in InterPro IPR036236, Znf_C2H2_sf IPR013087, Znf_C2H2_type |
Pfami | View protein in Pfam PF00096, zf-C2H2, 6 hits |
SMARTi | View protein in SMART SM00355, ZnF_C2H2, 7 hits |
SUPFAMi | SSF57667, SSF57667, 4 hits |
PROSITEi | View protein in PROSITE PS00028, ZINC_FINGER_C2H2_1, 6 hits PS50157, ZINC_FINGER_C2H2_2, 7 hits |
MobiDBi | Search... |
Entry informationi
Entry namei | ZNF32_MOUSE | |
Accessioni | Q80V23Primary (citable) accession number: Q80V23 Secondary accession number(s): Q3UIS3 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | January 10, 2006 |
Last sequence update: | June 1, 2003 | |
Last modified: | February 23, 2022 | |
This is version 134 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- MGD cross-references
Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot - SIMILARITY comments
Index of protein domains and families