UniProtKB - Q80V23 (ZNF32_MOUSE)

BLAST

>sp|Q80V23|ZNF32_MOUSE Zinc finger protein 32 OS=Mus musculus OX=10090 GN=Znf32 PE=2 SV=1
MFGFPTATLLDCHGRYAQNVAFFNVMTEAHKYDPSEATGSSSWDFQSSFRREKLEQKSPE
SKALQEDSPGVRQKVYDCQECGKSFRQKGSLTLHERIHTGQKPFECTQCGKSFRAKGNLV
THQRIHTGEKPYQCKECGKSFSQRGSLAVHERLHTGQKPYECAICQRSFRNQSNLAVHRR
VHSGEKPYRCDQCGKAFSQKGSLIVHIRVHTGLKPYACSHCRKSFHTRGNCLLHGKVHTG
ETPYLCGQCGKSFTQRGSLAVHQRSCSQRLTL

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History
Entry version 115 (10 Oct 2018)
Sequence version 1 (01 Jun 2003)
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Protein

Zinc finger protein 32

Gene

Znf32

Organism

Mus musculus (Mouse)

Status

Reviewed-Annotation score: -Experimental evidence at transcript levelⁱ

Functionⁱ

May be involved in transcriptional regulation.

Regions

Feature key	Position(s)	DescriptionActions	Length
Zinc fingerⁱ	76 – 98	C2H2-type 1PROSITE-ProRule annotationAdd BLAST	23
Zinc fingerⁱ	104 – 126	C2H2-type 2PROSITE-ProRule annotationAdd BLAST	23
Zinc fingerⁱ	132 – 154	C2H2-type 3PROSITE-ProRule annotationAdd BLAST	23
Zinc fingerⁱ	160 – 182	C2H2-type 4PROSITE-ProRule annotationAdd BLAST	23
Zinc fingerⁱ	188 – 210	C2H2-type 5PROSITE-ProRule annotationAdd BLAST	23
Zinc fingerⁱ	216 – 238	C2H2-type 6PROSITE-ProRule annotationAdd BLAST	23
Zinc fingerⁱ	244 – 265	C2H2-type 7; degeneratePROSITE-ProRule annotationAdd BLAST	22

GO - Molecular functionⁱ

metal ion binding Source: UniProtKB-KW
nucleic acid binding Source: InterPro

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Ligand	Metal-binding, Zinc

Ligand

Metal-binding, Zinc

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Zinc finger protein 32 Alternative name(s): Zinc finger protein 637
Gene namesⁱ	Name:Znf32 Synonyms:Zfp637
Organismⁱ	Mus musculus (Mouse)
Taxonomic identifierⁱ	10090 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus
Proteomesⁱ	UP000000589 Componentⁱ: Chromosome 6

Organism-specific databases

MGIⁱ	MGI:2448537 Zfp637

Keywords - Cellular componentⁱ

Nucleus

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000047362	1 – 272	Zinc finger protein 32Add BLAST		272

Proteomic databases

PaxDbⁱ	Q80V23
PRIDEⁱ	Q80V23

PTM databases

iPTMnetⁱ	Q80V23
PhosphoSitePlusⁱ	Q80V23

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSMUSG00000059689 Expressed in 259 organ(s), highest expression level in pes
CleanExⁱ	MM_ZFP637
ExpressionAtlasⁱ	Q80V23 baseline and differential
Genevisibleⁱ	Q80V23 MM

Interactionⁱ

Protein-protein interaction databases

STRINGⁱ	10090.ENSMUSP00000108482

STRINGⁱ

10090.ENSMUSP00000108482

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	Q80V23
SMRⁱ	Q80V23
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Sequence similaritiesⁱ

Belongs to the krueppel C2H2-type zinc-finger protein family.Curated

Zinc finger

Feature key	Position(s)	DescriptionActions	Length
Zinc fingerⁱ	76 – 98	C2H2-type 1PROSITE-ProRule annotationAdd BLAST	23
Zinc fingerⁱ	104 – 126	C2H2-type 2PROSITE-ProRule annotationAdd BLAST	23
Zinc fingerⁱ	132 – 154	C2H2-type 3PROSITE-ProRule annotationAdd BLAST	23
Zinc fingerⁱ	160 – 182	C2H2-type 4PROSITE-ProRule annotationAdd BLAST	23
Zinc fingerⁱ	188 – 210	C2H2-type 5PROSITE-ProRule annotationAdd BLAST	23
Zinc fingerⁱ	216 – 238	C2H2-type 6PROSITE-ProRule annotationAdd BLAST	23
Zinc fingerⁱ	244 – 265	C2H2-type 7; degeneratePROSITE-ProRule annotationAdd BLAST	22

Keywords - Domainⁱ

Repeat, Zinc-finger

Phylogenomic databases

eggNOGⁱ	KOG1721 Eukaryota COG5048 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00900000141051
HOGENOMⁱ	HOG000234617
HOVERGENⁱ	HBG018163
InParanoidⁱ	Q80V23
OMAⁱ	DVMTEAH
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G02KC
PhylomeDBⁱ	Q80V23
TreeFamⁱ	TF337055

Family and domain databases

InterProⁱ	View protein in InterPro IPR036236 Znf_C2H2_sf IPR013087 Znf_C2H2_type
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00096 zf-C2H2, 6 hits
SMARTⁱ	View protein in SMART SM00355 ZnF_C2H2, 7 hits
SUPFAMⁱ	SSF57667 SSF57667, 4 hits
PROSITEⁱ	View protein in PROSITE PS00028 ZINC_FINGER_C2H2_1, 6 hits PS50157 ZINC_FINGER_C2H2_2, 7 hits

Sequences (2+)ⁱ

Sequence statusⁱ: Complete.

This entry describes 2 isoformsⁱ produced by alternative splicing. Align Add to basket

This entry has 2 described isoforms and 3 potential isoforms that are computationally mapped.Show all Align All

Isoform 1 (identifier: Q80V23-1) [UniParc]FASTA Add to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MFGFPTATLL DCHGRYAQNV AFFNVMTEAH KYDPSEATGS SSWDFQSSFR 
        60         70         80         90        100
REKLEQKSPE SKALQEDSPG VRQKVYDCQE CGKSFRQKGS LTLHERIHTG 
       110        120        130        140        150
QKPFECTQCG KSFRAKGNLV THQRIHTGEK PYQCKECGKS FSQRGSLAVH 
       160        170        180        190        200
ERLHTGQKPY ECAICQRSFR NQSNLAVHRR VHSGEKPYRC DQCGKAFSQK 
       210        220        230        240        250
GSLIVHIRVH TGLKPYACSH CRKSFHTRGN CLLHGKVHTG ETPYLCGQCG 
       260        270 
KSFTQRGSLA VHQRSCSQRL TL

Length:272

Mass (Da):30,773

Last modified:June 1, 2003 - v1

Checksum:ⁱF28BD2DF43BF418E

Isoform 2 (identifier: Q80V23-2) [UniParc]FASTA Add to basket

The sequence of this isoform differs from the canonical sequence as follows:
23-24: FN → FTYWCILHDFPLVLPD

« Hide

        10         20         30         40         50
MFGFPTATLL DCHGRYAQNV AFFTYWCILH DFPLVLPDVM TEAHKYDPSE 
        60         70         80         90        100
ATGSSSWDFQ SSFRREKLEQ KSPESKALQE DSPGVRQKVY DCQECGKSFR 
       110        120        130        140        150
QKGSLTLHER IHTGQKPFEC TQCGKSFRAK GNLVTHQRIH TGEKPYQCKE 
       160        170        180        190        200
CGKSFSQRGS LAVHERLHTG QKPYECAICQ RSFRNQSNLA VHRRVHSGEK 
       210        220        230        240        250
PYRCDQCGKA FSQKGSLIVH IRVHTGLKPY ACSHCRKSFH TRGNCLLHGK 
       260        270        280 
VHTGETPYLC GQCGKSFTQR GSLAVHQRSC SQRLTL

Note: No experimental confirmation available.

Show »

Length:286

Mass (Da):32,473

Checksum:ⁱ77D9CF44564409F0

Computationally mapped potential isoform sequencesⁱ

There are 3 potential isoforms mapped to this entry.BLAST Align Show all Add to basket

Entry	Entry name	Protein names	Gene names	Length	Annotation

D3Z0E5	D3Z0E5_MOUSE	Zinc finger protein 637 Zinc finger protein 637	Zfp637	202	Annotation score:
D3YYX3	D3YYX3_MOUSE	Zinc finger protein 637 Zinc finger protein 637	Zfp637	153	Annotation score:
D3Z3T2	D3Z3T2_MOUSE	Zinc finger protein 637 Zinc finger protein 637	Zfp637	33	Annotation score:

Alternative sequence

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Alternative sequenceⁱVSP_016954	23 – 24	FN → FTYWCILHDFPLVLPD in isoform 2. 1 Publication		2

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AK146789 mRNA Translation: BAE27433.1 BC048843 mRNA Translation: AAH48843.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS39607.1 [Q80V23-1] CCDS85139.1 [Q80V23-2]
NCBI Reference Sequences More...RefSeqⁱ	NP_001333576.1, NM_001346647.1 [Q80V23-2] NP_001333577.1, NM_001346648.1 [Q80V23-2] NP_001333578.1, NM_001346649.1 [Q80V23-1] NP_001333579.1, NM_001346650.1 [Q80V23-1] NP_001333580.1, NM_001346651.1 NP_001333581.1, NM_001346652.1 NP_001333582.1, NM_001346653.1 NP_808352.1, NM_177684.3 [Q80V23-1] XP_006506080.1, XM_006506017.3 [Q80V23-2]
UniGeneⁱ	Mm.290847

Genome annotation databases

Ensemblⁱ	ENSMUST00000112860; ENSMUSP00000108481; ENSMUSG00000059689 [Q80V23-2] ENSMUST00000112861; ENSMUSP00000108482; ENSMUSG00000059689 [Q80V23-1] ENSMUST00000164472; ENSMUSP00000130144; ENSMUSG00000059689 [Q80V23-1] ENSMUST00000223041; ENSMUSP00000152569; ENSMUSG00000059689 [Q80V23-2]
GeneIDⁱ	232337
KEGGⁱ	mmu:232337
UCSC genome browser More...UCSCⁱ	uc009dky.1 mouse [Q80V23-1] uc009dkz.1 mouse [Q80V23-2]

Keywords - Coding sequence diversityⁱ

Alternative splicing

Similar proteinsⁱ

100% Identity
90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length	Source
Q80V23	Zinc finger protein 637 (Fragment)		MOUSE		153	UniRef100_Q80V23
Q80V23-2	Zfp637 protein		MOUSE		247	UniRef100_Q05CR8
Zinc finger protein 637 (Fragment)		MOUSE		202

Protein	Similar proteins		Species	Score	Length	Source
Q80V23	Zinc finger protein 32	)	HUMAN		273	UniRef90_P17041
Zinc finger protein 32		MACMU		273
Zinc finger protein 32		CALJA		273
ZNF32 isoform 1		PANTR		273
Uncharacterized protein		RHIBE		273
+112
Q80V23-2	Uncharacterized protein		SHEEP		273	UniRef90_W5NYD9
Uncharacterized protein		FELCA		287
Uncharacterized protein		PIG		287
zinc finger protein 32 isoform X4		LEPWE		248
zinc finger protein 32 isoform X1		Florida manatee		287
+48

Protein	Similar proteins		Species	Score	Length	Source
Q80V23	Zinc finger protein 32	)	HUMAN		273	UniRef50_P17041
Zinc finger protein 32		MACMU		273
Zinc finger protein 32		CALJA		273
ZNF32 isoform 1		PANTR		273
Uncharacterized protein		RHIBE		273
+132
Q80V23-2	Uncharacterized protein		SHEEP		273	UniRef50_W5NYD9
Uncharacterized protein		LOXAF		287
zinc finger protein 32 isoform X1		Florida manatee		287
Uncharacterized protein		FELCA		287
Uncharacterized protein		PIG		287
+50

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AK146789 mRNA Translation: BAE27433.1 BC048843 mRNA Translation: AAH48843.1
CCDSⁱ	CCDS39607.1 [Q80V23-1] CCDS85139.1 [Q80V23-2]
RefSeqⁱ	NP_001333576.1, NM_001346647.1 [Q80V23-2] NP_001333577.1, NM_001346648.1 [Q80V23-2] NP_001333578.1, NM_001346649.1 [Q80V23-1] NP_001333579.1, NM_001346650.1 [Q80V23-1] NP_001333580.1, NM_001346651.1 NP_001333581.1, NM_001346652.1 NP_001333582.1, NM_001346653.1 NP_808352.1, NM_177684.3 [Q80V23-1] XP_006506080.1, XM_006506017.3 [Q80V23-2]
UniGeneⁱ	Mm.290847

3D structure databases

ProteinModelPortalⁱ	Q80V23
SMRⁱ	Q80V23
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

STRINGⁱ	10090.ENSMUSP00000108482

STRINGⁱ

10090.ENSMUSP00000108482

PTM databases

iPTMnetⁱ	Q80V23
PhosphoSitePlusⁱ	Q80V23

Proteomic databases

PaxDbⁱ	Q80V23
PRIDEⁱ	Q80V23

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENSMUST00000112860; ENSMUSP00000108481; ENSMUSG00000059689 [Q80V23-2] ENSMUST00000112861; ENSMUSP00000108482; ENSMUSG00000059689 [Q80V23-1] ENSMUST00000164472; ENSMUSP00000130144; ENSMUSG00000059689 [Q80V23-1] ENSMUST00000223041; ENSMUSP00000152569; ENSMUSG00000059689 [Q80V23-2]
GeneIDⁱ	232337
KEGGⁱ	mmu:232337
UCSCⁱ	uc009dky.1 mouse [Q80V23-1] uc009dkz.1 mouse [Q80V23-2]

Organism-specific databases

CTDⁱ	232337
MGIⁱ	MGI:2448537 Zfp637

Phylogenomic databases

eggNOGⁱ	KOG1721 Eukaryota COG5048 LUCA
GeneTreeⁱ	ENSGT00900000141051
HOGENOMⁱ	HOG000234617
HOVERGENⁱ	HBG018163
InParanoidⁱ	Q80V23
OMAⁱ	DVMTEAH
OrthoDBⁱ	EOG091G02KC
PhylomeDBⁱ	Q80V23
TreeFamⁱ	TF337055

Miscellaneous databases

Protein Ontology More...PROⁱ	PR:Q80V23
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSMUSG00000059689 Expressed in 259 organ(s), highest expression level in pes
CleanExⁱ	MM_ZFP637
ExpressionAtlasⁱ	Q80V23 baseline and differential
Genevisibleⁱ	Q80V23 MM

Family and domain databases

InterProⁱ	View protein in InterPro IPR036236 Znf_C2H2_sf IPR013087 Znf_C2H2_type
Pfamⁱ	View protein in Pfam PF00096 zf-C2H2, 6 hits
SMARTⁱ	View protein in SMART SM00355 ZnF_C2H2, 7 hits
SUPFAMⁱ	SSF57667 SSF57667, 4 hits
PROSITEⁱ	View protein in PROSITE PS00028 ZINC_FINGER_C2H2_1, 6 hits PS50157 ZINC_FINGER_C2H2_2, 7 hits
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	ZNF32_MOUSE
Accessionⁱ	Q80V23Primary (citable) accession number: Q80V23 Secondary accession number(s): Q3UIS3
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	January 10, 2006
	Last sequence update:	June 1, 2003
	Last modified:	October 10, 2018
	This is version 115 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

Documents

SIMILARITY comments
Index of protein domains and families
MGD cross-references
Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - Q80V23 (ZNF32_MOUSE)

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Zinc finger protein 32

Znf32

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Regions

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Nucleus

Nucleus

Keywords - Cellular componenti

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Zinc finger

Keywords - Domaini

Phylogenomic databases

Family and domain databases

Alternative sequence

Sequence databases

Genome annotation databases

Keywords - Coding sequence diversityi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Documents

UniProt is an ELIXIR core data resource

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Functionⁱ

GO - Molecular functionⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Keywords - Cellular componentⁱ

PTM / Processingⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Keywords - Domainⁱ

Keywords - Coding sequence diversityⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ