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Protein

Zinc finger protein 32

Gene

Znf32

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

May be involved in transcriptional regulation.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri76 – 98C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri104 – 126C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri132 – 154C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri160 – 182C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri188 – 210C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri216 – 238C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri244 – 265C2H2-type 7; degeneratePROSITE-ProRule annotationAdd BLAST22

GO - Molecular functioni

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Zinc finger protein 32
Alternative name(s):
Zinc finger protein 637
Gene namesi
Name:Znf32
Synonyms:Zfp637
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 6

Organism-specific databases

MGIiMGI:2448537 Zfp637

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000473621 – 272Zinc finger protein 32Add BLAST272

Proteomic databases

PaxDbiQ80V23
PRIDEiQ80V23

PTM databases

iPTMnetiQ80V23
PhosphoSitePlusiQ80V23

Expressioni

Gene expression databases

BgeeiENSMUSG00000059689 Expressed in 259 organ(s), highest expression level in pes
CleanExiMM_ZFP637
ExpressionAtlasiQ80V23 baseline and differential
GenevisibleiQ80V23 MM

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000108482

Structurei

3D structure databases

ProteinModelPortaliQ80V23
SMRiQ80V23
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri76 – 98C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri104 – 126C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri132 – 154C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri160 – 182C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri188 – 210C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri216 – 238C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri244 – 265C2H2-type 7; degeneratePROSITE-ProRule annotationAdd BLAST22

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

eggNOGiKOG1721 Eukaryota
COG5048 LUCA
GeneTreeiENSGT00900000141051
HOGENOMiHOG000234617
HOVERGENiHBG018163
InParanoidiQ80V23
OMAiDVMTEAH
OrthoDBiEOG091G02KC
PhylomeDBiQ80V23
TreeFamiTF337055

Family and domain databases

InterProiView protein in InterPro
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
PfamiView protein in Pfam
PF00096 zf-C2H2, 6 hits
SMARTiView protein in SMART
SM00355 ZnF_C2H2, 7 hits
SUPFAMiSSF57667 SSF57667, 4 hits
PROSITEiView protein in PROSITE
PS00028 ZINC_FINGER_C2H2_1, 6 hits
PS50157 ZINC_FINGER_C2H2_2, 7 hits

Sequences (2+)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 3 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q80V23-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MFGFPTATLL DCHGRYAQNV AFFNVMTEAH KYDPSEATGS SSWDFQSSFR
60 70 80 90 100
REKLEQKSPE SKALQEDSPG VRQKVYDCQE CGKSFRQKGS LTLHERIHTG
110 120 130 140 150
QKPFECTQCG KSFRAKGNLV THQRIHTGEK PYQCKECGKS FSQRGSLAVH
160 170 180 190 200
ERLHTGQKPY ECAICQRSFR NQSNLAVHRR VHSGEKPYRC DQCGKAFSQK
210 220 230 240 250
GSLIVHIRVH TGLKPYACSH CRKSFHTRGN CLLHGKVHTG ETPYLCGQCG
260 270
KSFTQRGSLA VHQRSCSQRL TL
Length:272
Mass (Da):30,773
Last modified:June 1, 2003 - v1
Checksum:iF28BD2DF43BF418E
GO
Isoform 2 (identifier: Q80V23-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     23-24: FN → FTYWCILHDFPLVLPD

Note: No experimental confirmation available.
Show »
Length:286
Mass (Da):32,473
Checksum:i77D9CF44564409F0
GO

Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
D3Z0E5D3Z0E5_MOUSE
Zinc finger protein 637
Zfp637
202Annotation score:
D3YYX3D3YYX3_MOUSE
Zinc finger protein 637
Zfp637
153Annotation score:
D3Z3T2D3Z3T2_MOUSE
Zinc finger protein 637
Zfp637
33Annotation score:

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_01695423 – 24FN → FTYWCILHDFPLVLPD in isoform 2. 1 Publication2

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK146789 mRNA Translation: BAE27433.1
BC048843 mRNA Translation: AAH48843.1
CCDSiCCDS39607.1 [Q80V23-1]
CCDS85139.1 [Q80V23-2]
RefSeqiNP_001333576.1, NM_001346647.1 [Q80V23-2]
NP_001333577.1, NM_001346648.1 [Q80V23-2]
NP_001333578.1, NM_001346649.1 [Q80V23-1]
NP_001333579.1, NM_001346650.1 [Q80V23-1]
NP_001333580.1, NM_001346651.1
NP_001333581.1, NM_001346652.1
NP_001333582.1, NM_001346653.1
NP_808352.1, NM_177684.3 [Q80V23-1]
XP_006506080.1, XM_006506017.3 [Q80V23-2]
UniGeneiMm.290847

Genome annotation databases

EnsembliENSMUST00000112860; ENSMUSP00000108481; ENSMUSG00000059689 [Q80V23-2]
ENSMUST00000112861; ENSMUSP00000108482; ENSMUSG00000059689 [Q80V23-1]
ENSMUST00000164472; ENSMUSP00000130144; ENSMUSG00000059689 [Q80V23-1]
ENSMUST00000223041; ENSMUSP00000152569; ENSMUSG00000059689 [Q80V23-2]
GeneIDi232337
KEGGimmu:232337
UCSCiuc009dky.1 mouse [Q80V23-1]
uc009dkz.1 mouse [Q80V23-2]

Keywords - Coding sequence diversityi

Alternative splicing

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK146789 mRNA Translation: BAE27433.1
BC048843 mRNA Translation: AAH48843.1
CCDSiCCDS39607.1 [Q80V23-1]
CCDS85139.1 [Q80V23-2]
RefSeqiNP_001333576.1, NM_001346647.1 [Q80V23-2]
NP_001333577.1, NM_001346648.1 [Q80V23-2]
NP_001333578.1, NM_001346649.1 [Q80V23-1]
NP_001333579.1, NM_001346650.1 [Q80V23-1]
NP_001333580.1, NM_001346651.1
NP_001333581.1, NM_001346652.1
NP_001333582.1, NM_001346653.1
NP_808352.1, NM_177684.3 [Q80V23-1]
XP_006506080.1, XM_006506017.3 [Q80V23-2]
UniGeneiMm.290847

3D structure databases

ProteinModelPortaliQ80V23
SMRiQ80V23
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000108482

PTM databases

iPTMnetiQ80V23
PhosphoSitePlusiQ80V23

Proteomic databases

PaxDbiQ80V23
PRIDEiQ80V23

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000112860; ENSMUSP00000108481; ENSMUSG00000059689 [Q80V23-2]
ENSMUST00000112861; ENSMUSP00000108482; ENSMUSG00000059689 [Q80V23-1]
ENSMUST00000164472; ENSMUSP00000130144; ENSMUSG00000059689 [Q80V23-1]
ENSMUST00000223041; ENSMUSP00000152569; ENSMUSG00000059689 [Q80V23-2]
GeneIDi232337
KEGGimmu:232337
UCSCiuc009dky.1 mouse [Q80V23-1]
uc009dkz.1 mouse [Q80V23-2]

Organism-specific databases

CTDi232337
MGIiMGI:2448537 Zfp637

Phylogenomic databases

eggNOGiKOG1721 Eukaryota
COG5048 LUCA
GeneTreeiENSGT00900000141051
HOGENOMiHOG000234617
HOVERGENiHBG018163
InParanoidiQ80V23
OMAiDVMTEAH
OrthoDBiEOG091G02KC
PhylomeDBiQ80V23
TreeFamiTF337055

Miscellaneous databases

PROiPR:Q80V23
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000059689 Expressed in 259 organ(s), highest expression level in pes
CleanExiMM_ZFP637
ExpressionAtlasiQ80V23 baseline and differential
GenevisibleiQ80V23 MM

Family and domain databases

InterProiView protein in InterPro
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
PfamiView protein in Pfam
PF00096 zf-C2H2, 6 hits
SMARTiView protein in SMART
SM00355 ZnF_C2H2, 7 hits
SUPFAMiSSF57667 SSF57667, 4 hits
PROSITEiView protein in PROSITE
PS00028 ZINC_FINGER_C2H2_1, 6 hits
PS50157 ZINC_FINGER_C2H2_2, 7 hits
ProtoNetiSearch...

Entry informationi

Entry nameiZNF32_MOUSE
AccessioniPrimary (citable) accession number: Q80V23
Secondary accession number(s): Q3UIS3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 10, 2006
Last sequence update: June 1, 2003
Last modified: October 10, 2018
This is version 115 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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