UniProtKB - Q80UV9 (TAF1_MOUSE)
Transcription initiation factor TFIID subunit 1
Taf1
Functioni
Catalytic activityi
Cofactori
Activity regulationi
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
DNA bindingi | 1216 – 1294 | HMG boxBy similarityAdd BLAST | 79 |
GO - Molecular functioni
- ATP binding Source: UniProtKB-KW
- DNA binding Source: MGI
- DNA-binding transcription factor inhibitor activity Source: MGI
- histone acetyltransferase activity Source: UniProtKB
- kinase activity Source: MGI
- lysine-acetylated histone binding Source: MGI
- nuclear hormone receptor binding Source: MGI
- p53 binding Source: MGI
- promoter-specific chromatin binding Source: MGI
- protein heterodimerization activity Source: MGI
- protein kinase activity Source: MGI
- protein serine/threonine kinase activity Source: MGI
- protein serine kinase activity Source: UniProtKB-EC
- protein threonine kinase activity Source: UniProtKB-EC
- RNA polymerase I general transcription initiation factor activity Source: MGI
- RNA polymerase II core promoter sequence-specific DNA binding Source: MGI
- RNA polymerase II general transcription initiation factor activity Source: MGI
- RNA polymerase II-specific DNA-binding transcription factor binding Source: MGI
- TBP-class protein binding Source: MGI
- transcription factor binding Source: MGI
- ubiquitin conjugating enzyme activity Source: MGI
GO - Biological processi
- cell cycle Source: UniProtKB-KW
- cellular response to ATP Source: MGI
- cellular response to DNA damage stimulus Source: MGI
- cellular response to UV Source: MGI
- histone acetylation Source: UniProtKB
- midbrain development Source: MGI
- negative regulation of DNA-binding transcription factor activity Source: MGI
- negative regulation of gene expression Source: MGI
- negative regulation of protein autoubiquitination Source: MGI
- negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding Source: MGI
- negative regulation of transcription by RNA polymerase II Source: MGI
- negative regulation of ubiquitin-dependent protein catabolic process Source: MGI
- peptidyl-serine phosphorylation Source: MGI
- peptidyl-threonine phosphorylation Source: MGI
- positive regulation of androgen receptor activity Source: MGI
- positive regulation of proteasomal ubiquitin-dependent protein catabolic process Source: MGI
- positive regulation of protein binding Source: MGI
- protein autophosphorylation Source: MGI
- protein phosphorylation Source: MGI
- protein polyubiquitination Source: MGI
- protein stabilization Source: MGI
- RNA polymerase II preinitiation complex assembly Source: GO_Central
- transcription by RNA polymerase II Source: MGI
- transcription factor catabolic process Source: MGI
- transcription initiation from RNA polymerase II promoter Source: MGI
- transcription initiation from RNA polymerase I promoter Source: MGI
- ubiquitin-dependent protein catabolic process Source: MGI
Keywordsi
Molecular function | Acyltransferase, DNA-binding, Kinase, Serine/threonine-protein kinase, Transferase |
Biological process | Cell cycle, Transcription, Transcription regulation |
Ligand | ATP-binding, Nucleotide-binding |
Enzyme and pathway databases
Reactomei | R-MMU-674695, RNA Polymerase II Pre-transcription Events R-MMU-6804756, Regulation of TP53 Activity through Phosphorylation R-MMU-73776, RNA Polymerase II Promoter Escape R-MMU-73779, RNA Polymerase II Transcription Pre-Initiation And Promoter Opening R-MMU-75953, RNA Polymerase II Transcription Initiation R-MMU-76042, RNA Polymerase II Transcription Initiation And Promoter Clearance |
Names & Taxonomyi
Protein namesi | Recommended name: Transcription initiation factor TFIID subunit 1 (EC:2.3.1.48By similarity, EC:2.7.11.1)Alternative name(s): Cell cycle gene 1 protein TBP-associated factor 250 kDa Short name: p250 Transcription initiation factor TFIID 250 kDa subunit Short name: TAF(II)250 Short name: TAFII-250 Short name: TAFII250 |
Gene namesi | Name:Taf1 Synonyms:Ccg1 |
Organismi | Mus musculus (Mouse) |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Proteomesi |
|
Organism-specific databases
MGIi | MGI:1336878, Taf1 |
Subcellular locationi
Nucleus
- Nucleus By similarity
Nucleus
- MLL1 complex Source: UniProtKB
- nuclear chromatin Source: MGI
- nucleoplasm Source: MGI
- nucleus Source: MGI
- pronucleus Source: MGI
- transcription factor TFIID complex Source: UniProtKB
Other locations
- transcription regulator complex Source: MGI
Keywords - Cellular componenti
NucleusPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000278524 | 1 – 1891 | Transcription initiation factor TFIID subunit 1Add BLAST | 1891 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 328 | Phosphoserine; by autocatalysisBy similarity | 1 | |
Modified residuei | 565 | N6-acetyllysineCombined sources | 1 | |
Cross-linki | 570 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity | ||
Cross-linki | 583 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity | ||
Modified residuei | 1690 | PhosphoserineCombined sources | 1 | |
Modified residuei | 1693 | PhosphoserineCombined sources | 1 | |
Modified residuei | 1799 | PhosphoserineCombined sources | 1 | |
Modified residuei | 1802 | PhosphoserineCombined sources | 1 | |
Modified residuei | 1820 | PhosphoserineCombined sources | 1 | |
Modified residuei | 1847 | PhosphoserineBy similarity | 1 |
Post-translational modificationi
Keywords - PTMi
Acetylation, Isopeptide bond, Phosphoprotein, Ubl conjugationProteomic databases
PaxDbi | Q80UV9 |
PeptideAtlasi | Q80UV9 |
PRIDEi | Q80UV9 |
PTM databases
iPTMneti | Q80UV9 |
PhosphoSitePlusi | Q80UV9 |
Expressioni
Gene expression databases
Bgeei | ENSMUSG00000031314, Expressed in manus and 266 other tissues |
ExpressionAtlasi | Q80UV9, baseline and differential |
Genevisiblei | Q80UV9, MM |
Interactioni
Subunit structurei
TAF1 is the largest component of transcription factor TFIID that is composed of TBP and a variety of TBP-associated factors (PubMed:10438527). TAF1, when part of the TFIID complex, interacts with C-terminus of TP53.
Part of a TFIID-containing RNA polymerase II pre-initiation complex that is composed of TBP and at least GTF2A1, GTF2A2, GTF2E1, GTF2E2, GTF2F1, GTF2H2, GTF2H3, GTF2H4, GTF2H5, GTF2B, TCEA1, ERCC2, ERCC3, TAF1, TAF2, TAF3, TAF4, TAF5, TAF6, TAF7, TAF8, TAF9, TAF10, TAF11, TAF12 and TAF13.
Interacts with TAF7; the interaction is direct.
Component of some MLL1/MLL complex, at least composed of the core components KMT2A/MLL1, ASH2L, HCFC1/HCF1, WDR5 and RBBP5, as well as the facultative components BAP18, CHD8, E2F6, HSP70, INO80C, KANSL1, LAS1L, MAX, MCRS1, MGA, KAT8/MOF, PELP1, PHF20, PRP31, RING2, RUVB1/TIP49A, RUVB2/TIP49B, SENP3, TAF1, TAF4, TAF6, TAF7, TAF9 and TEX10. RB1 interacts with the N-terminal domain of TAF1.
Interacts with ASF1A and ASF1B.
Interacts (via bromo domains) with acetylated lysine residues on the N-terminus of histone H1.4, H2A, H2B, H3 and H4 (in vitro) (By similarity).
By similarityBinary interactionsi
Isoform 1 [Q80UV9-1]
With | #Exp. | IntAct |
---|---|---|
TAF7 [Q15545] from Homo sapiens. | 2 | EBI-15563115,EBI-1560194 |
GO - Molecular functioni
- lysine-acetylated histone binding Source: MGI
- nuclear hormone receptor binding Source: MGI
- p53 binding Source: MGI
- protein heterodimerization activity Source: MGI
- RNA polymerase II-specific DNA-binding transcription factor binding Source: MGI
- TBP-class protein binding Source: MGI
- transcription factor binding Source: MGI
Protein-protein interaction databases
BioGRIDi | 234808, 13 interactors |
ComplexPortali | CPX-932, General transcription factor complex TFIID CPX-959, General transcription factor complex TFIID, Taf4b variant |
CORUMi | Q80UV9 |
DIPi | DIP-61093N |
IntActi | Q80UV9, 1 interactor |
STRINGi | 10090.ENSMUSP00000098895 |
Miscellaneous databases
RNActi | Q80UV9, protein |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 1 – 435 | Protein kinase 1Add BLAST | 435 | |
Domaini | 1418 – 1488 | Bromo 1PROSITE-ProRule annotationAdd BLAST | 71 | |
Domaini | 1446 – 1891 | Protein kinase 2Add BLAST | 446 | |
Domaini | 1541 – 1611 | Bromo 2PROSITE-ProRule annotationAdd BLAST | 71 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 538 – 997 | Histone acetyltransferase (HAT)By similarityAdd BLAST | 460 | |
Regioni | 1363 – 1650 | Interaction with ASF1A and ASF1BBy similarityAdd BLAST | 288 |
Motif
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Motifi | 1372 – 1379 | Nuclear localization signalSequence analysis | 8 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 157 – 165 | Poly-Pro | 9 | |
Compositional biasi | 204 – 211 | Poly-Ser | 8 | |
Compositional biasi | 1848 – 1855 | Poly-Glu | 8 |
Domaini
Sequence similaritiesi
Keywords - Domaini
Bromodomain, RepeatPhylogenomic databases
eggNOGi | KOG0008, Eukaryota |
GeneTreei | ENSGT00940000155242 |
InParanoidi | Q80UV9 |
OMAi | KACPLYT |
OrthoDBi | 103411at2759 |
Family and domain databases
Gene3Di | 1.10.1100.10, 1 hit 1.20.920.10, 2 hits |
InterProi | View protein in InterPro IPR001487, Bromodomain IPR036427, Bromodomain-like_sf IPR018359, Bromodomain_CS IPR040240, TAF1 IPR011177, TAF1_animal IPR009067, TAF_II_230-bd IPR036741, TAFII-230_TBP-bd_sf IPR022591, TFIID_sub1_DUF3591 IPR041670, Znf-CCHC_6 |
PANTHERi | PTHR13900, PTHR13900, 1 hit |
Pfami | View protein in Pfam PF00439, Bromodomain, 2 hits PF12157, DUF3591, 1 hit PF09247, TBP-binding, 1 hit PF15288, zf-CCHC_6, 1 hit |
PIRSFi | PIRSF003047, TAF1_animal, 1 hit |
PRINTSi | PR00503, BROMODOMAIN |
SMARTi | View protein in SMART SM00297, BROMO, 2 hits |
SUPFAMi | SSF47055, SSF47055, 1 hit SSF47370, SSF47370, 2 hits |
PROSITEi | View protein in PROSITE PS00633, BROMODOMAIN_1, 2 hits PS50014, BROMODOMAIN_2, 2 hits |
s (3+)i Sequence
Sequence statusi: Complete.
This entry describes 3 produced by isoformsialternative splicing. AlignAdd to basketThis entry has 3 described isoforms and 3 potential isoforms that are computationally mapped.Show allAlign All
This isoform has been chosen as the sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. canonicali
10 20 30 40 50
MGPGWAGLLQ DKGGGSPSVV MSDTDSDEES AGGGPFSLTG FLFGNINGAG
60 70 80 90 100
QLEGESVLDD ECKKHLAGLG ALGLGSLITE LTANEELSGS DGALVNDEGW
110 120 130 140 150
IRSREDAVDY SDINEVAEDE SRRYQQTMGS LQPLCHTDYD EDDYDADCED
160 170 180 190 200
IDCKLMPPPP PPPGPLKKEK DQDDITGVSE DGEGIILPSI IAPSSLASEK
210 220 230 240 250
VDFSSSSDSE SEMGPQDAAQ SESKDGQLTL PLAGIMQHDA TKLLPSVTEL
260 270 280 290 300
FPEFRPGKVL RFLRLFGPGK NVPSVWRSAR RKRKKKHREL IQEGQVQEEE
310 320 330 340 350
CSVELEVNQK SLWNYDYAPP PLPDQCLSDD EITMMAPVES KFSQSTGDTD
360 370 380 390 400
KVMDTKPRVA EWRYGPARLW YDMLGVPEDG SGFDYGFKMK KTEHESTIKC
410 420 430 440 450
NIMKKLRKLE ENSGVDLLAD ENFLMVTQLH WEDDIIWDGE DVKHKGTKPQ
460 470 480 490 500
RASLAGWLPS SMTRNAMAYN VQQGFTATLD DDKPWYSIFP IDNEDLVYGR
510 520 530 540 550
WEDNIIWDAQ NMPRILEPPV LTLDPNDENL ILEIPDEKEE ATSNSPSKEN
560 570 580 590 600
KKESSLKKSR ILLGKTGVIK EEPQQNMSQP EVKDPWNLSN DEYYYPKQQG
610 620 630 640 650
LRGTFGGNII QHSIPAVELR QPFFPTHMGP IKLRQFHRPP LKKYSFGALS
660 670 680 690 700
QPGPHSVQPL LKHIKKKAKM REQERQASGG GEMFFMRTPQ DLTGKDGDLI
710 720 730 740 750
LAEYSEENGP LMMQVGMATK IKNYYKRKPG KDPGAPDCKY GETVYCHTSP
760 770 780 790 800
FLGSLHPGQL LQAFENNLFR APIYLHKMPE SDFLIIRTRQ GYFIRELVDI
810 820 830 840 850
FVVGQQCPLF EVPGPNSKRA NTHIRDFLQV FIYRLFWKSK DRPRRIRMED
860 870 880 890 900
IKKAFPSHSE SSIRKRLKLC ADFKRTGMDS NWWVLKSDFR LPTEEEIRAM
910 920 930 940 950
VSPEQCCAYY SMIAAEQRLK DAGYGEKSFF APEEENEEDF QMKIDDEVRT
960 970 980 990 1000
APWNTTRAFI AAMKGKCLLE VTGVADPTGC GEGFSYVKIP NKPTQQKDDK
1010 1020 1030 1040 1050
EPQPVKKTVT GTDADLRRLS LKNAKQLLRK FGVPEEEIKK LSRWEVIDVV
1060 1070 1080 1090 1100
RTMSTEQARS GEGPMSKFAR GSRFSVAEHQ ERYKEECQRI FDLQNKVLSS
1110 1120 1130 1140 1150
TEVLSTDTDS SSAEDSDFEE MGKNIENMLQ NKKTSSQLSR EREEQERKEL
1160 1170 1180 1190 1200
QRMLLAAGSA AAGNNHRDDD TASVTSLNSS ATGRCLKIYR TFRDEEGKEY
1210 1220 1230 1240 1250
VRCETVRKAT VIDAYVRIRT TKDEEFIRKF ALFDEQHREE MRKERRRIQE
1260 1270 1280 1290 1300
QLRRLKRNQE KEKLKGPPEK KPKKMKERPD LKLKCGACGA IGHMRTNKFC
1310 1320 1330 1340 1350
PLYYQTNAPP SNPVAMTEEQ EEELEKTVIH NDNEELIKVE GTKIVLGKQL
1360 1370 1380 1390 1400
IESADEVRRK SLVLKFPKQQ LPPKKKRRVG TTVHCDYLNR PHKSIHRRRT
1410 1420 1430 1440 1450
DPMVTLSSIL ESIINDMRDL PNTYPFHTPV NAKVVKDYYK IITRPMDLQT
1460 1470 1480 1490 1500
LRENVRKRLY PSREEFREHL ELIVKNSATY NGPKHSLTQI SQSMLDLCDE
1510 1520 1530 1540 1550
KLKEKEDKLA RLEKAINPLL DDDDQVAFSF ILDNIVTQKM MAVPDSWPFH
1560 1570 1580 1590 1600
HPVNKKFVPD YYKVIVSPMD LETIRKNISK HKYQSRESFL DDVNLILANS
1610 1620 1630 1640 1650
VKYNGPESQY TKTAQEIVNV CHQTLTEYDE HLTQLEKDIC TAKEAALEEA
1660 1670 1680 1690 1700
ELESLDPMTP GPYTPQPPDL YDNNTSLSVS RDASVYQDES NLSVLDIPSA
1710 1720 1730 1740 1750
TSEKQLTQEG GDGDGDLADE EEGTVQQPQA SVLYEDLLMS EGEDDEEDAG
1760 1770 1780 1790 1800
SDEEGDNPFF AIQLSESGSD SDVESGSLRP KQPRVLQENT RMGMENEESM
1810 1820 1830 1840 1850
MSYEGDGGDA SRGLEDSNIS YGSYEEPDPK SNTQDTSFSS IGGYEVSEEE
1860 1870 1880 1890
EDEEEQRSGP SVLSQVHLSE DEEDSEDFHS IAGDTDLDSD E
Computationally mapped potential isoform sequencesi
There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketB1Q2W7 | B1Q2W7_MOUSE | Transcription initiation factor TFI... | Taf1 N-TAF1 | 1,893 | Annotation score: | ||
D3YZK4 | D3YZK4_MOUSE | Transcription initiation factor TFI... | Taf1 | 1,902 | Annotation score: | ||
S4R1B9 | S4R1B9_MOUSE | Transcription initiation factor TFI... | Taf1 | 1,733 | Annotation score: |
Sequence cautioni
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 217 | D → E in AAD23348 (PubMed:10070062).Curated | 1 | |
Sequence conflicti | 221 | S → A in AAD23348 (PubMed:10070062).Curated | 1 | |
Sequence conflicti | 261 | R → H in AAD23348 (PubMed:10070062).Curated | 1 | |
Sequence conflicti | 289 | E → K in AAD23348 (PubMed:10070062).Curated | 1 | |
Sequence conflicti | 867 – 868 | LK → EG in AAC62118 (PubMed:9751712).Curated | 2 | |
Sequence conflicti | 876 | T → Q in AAD23349 (PubMed:10070062).Curated | 1 | |
Sequence conflicti | 1302 – 1306 | LYYQT → AFVAS in AAC62118 (PubMed:9751712).Curated | 5 | |
Sequence conflicti | 1358 | R → P in AAD23350 (PubMed:10070062).Curated | 1 | |
Sequence conflicti | 1388 | L → F in AAD23350 (PubMed:10070062).Curated | 1 | |
Sequence conflicti | 1450 | T → E in AAD23350 (PubMed:10070062).Curated | 1 | |
Sequence conflicti | 1469 – 1470 | HL → QM in AAD23350 (PubMed:10070062).Curated | 2 | |
Sequence conflicti | 1736 | D → N in AAH94568 (PubMed:15489334).Curated | 1 |
Alternative sequence
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Alternative sequenceiVSP_023320 | 1 – 962 | Missing in isoform 2. 1 PublicationAdd BLAST | 962 | |
Alternative sequenceiVSP_023321 | 178 – 198 | Missing in isoform 3. 1 PublicationAdd BLAST | 21 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL806534 Genomic DNA No translation available. AL831722 Genomic DNA No translation available. BC047418 mRNA Translation: AAH47418.1 BC094568 mRNA Translation: AAH94568.1 AK045586 mRNA Translation: BAC32425.1 AK046668 mRNA Translation: BAC32828.1 AK049826 mRNA Translation: BAC33938.1 AK050691 mRNA Translation: BAC34383.1 Different initiation. AK132088 mRNA Translation: BAE20976.1 AK143571 mRNA Translation: BAE25442.1 AF081115 mRNA Translation: AAD23349.1 AF081116 mRNA Translation: AAD23348.1 AF081117 mRNA Translation: AAD23350.1 AF022178 mRNA Translation: AAC62118.1 |
RefSeqi | NP_001277658.1, NM_001290729.1 XP_006528113.1, XM_006528050.3 [Q80UV9-1] XP_006528115.1, XM_006528052.3 [Q80UV9-3] |
Genome annotation databases
Ensembli | ENSMUST00000118878; ENSMUSP00000112772; ENSMUSG00000031314 [Q80UV9-3] |
GeneIDi | 270627 |
KEGGi | mmu:270627 |
UCSCi | uc009txy.1, mouse [Q80UV9-2] |
Keywords - Coding sequence diversityi
Alternative splicingSimilar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL806534 Genomic DNA No translation available. AL831722 Genomic DNA No translation available. BC047418 mRNA Translation: AAH47418.1 BC094568 mRNA Translation: AAH94568.1 AK045586 mRNA Translation: BAC32425.1 AK046668 mRNA Translation: BAC32828.1 AK049826 mRNA Translation: BAC33938.1 AK050691 mRNA Translation: BAC34383.1 Different initiation. AK132088 mRNA Translation: BAE20976.1 AK143571 mRNA Translation: BAE25442.1 AF081115 mRNA Translation: AAD23349.1 AF081116 mRNA Translation: AAD23348.1 AF081117 mRNA Translation: AAD23350.1 AF022178 mRNA Translation: AAC62118.1 |
RefSeqi | NP_001277658.1, NM_001290729.1 XP_006528113.1, XM_006528050.3 [Q80UV9-1] XP_006528115.1, XM_006528052.3 [Q80UV9-3] |
3D structure databases
SMRi | Q80UV9 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 234808, 13 interactors |
ComplexPortali | CPX-932, General transcription factor complex TFIID CPX-959, General transcription factor complex TFIID, Taf4b variant |
CORUMi | Q80UV9 |
DIPi | DIP-61093N |
IntActi | Q80UV9, 1 interactor |
STRINGi | 10090.ENSMUSP00000098895 |
PTM databases
iPTMneti | Q80UV9 |
PhosphoSitePlusi | Q80UV9 |
Proteomic databases
PaxDbi | Q80UV9 |
PeptideAtlasi | Q80UV9 |
PRIDEi | Q80UV9 |
Genome annotation databases
Ensembli | ENSMUST00000118878; ENSMUSP00000112772; ENSMUSG00000031314 [Q80UV9-3] |
GeneIDi | 270627 |
KEGGi | mmu:270627 |
UCSCi | uc009txy.1, mouse [Q80UV9-2] |
Organism-specific databases
CTDi | 6872 |
MGIi | MGI:1336878, Taf1 |
Phylogenomic databases
eggNOGi | KOG0008, Eukaryota |
GeneTreei | ENSGT00940000155242 |
InParanoidi | Q80UV9 |
OMAi | KACPLYT |
OrthoDBi | 103411at2759 |
Enzyme and pathway databases
Reactomei | R-MMU-674695, RNA Polymerase II Pre-transcription Events R-MMU-6804756, Regulation of TP53 Activity through Phosphorylation R-MMU-73776, RNA Polymerase II Promoter Escape R-MMU-73779, RNA Polymerase II Transcription Pre-Initiation And Promoter Opening R-MMU-75953, RNA Polymerase II Transcription Initiation R-MMU-76042, RNA Polymerase II Transcription Initiation And Promoter Clearance |
Miscellaneous databases
BioGRID-ORCSi | 270627, 7 hits in 16 CRISPR screens |
ChiTaRSi | Taf1, mouse |
PROi | PR:Q80UV9 |
RNActi | Q80UV9, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSMUSG00000031314, Expressed in manus and 266 other tissues |
ExpressionAtlasi | Q80UV9, baseline and differential |
Genevisiblei | Q80UV9, MM |
Family and domain databases
Gene3Di | 1.10.1100.10, 1 hit 1.20.920.10, 2 hits |
InterProi | View protein in InterPro IPR001487, Bromodomain IPR036427, Bromodomain-like_sf IPR018359, Bromodomain_CS IPR040240, TAF1 IPR011177, TAF1_animal IPR009067, TAF_II_230-bd IPR036741, TAFII-230_TBP-bd_sf IPR022591, TFIID_sub1_DUF3591 IPR041670, Znf-CCHC_6 |
PANTHERi | PTHR13900, PTHR13900, 1 hit |
Pfami | View protein in Pfam PF00439, Bromodomain, 2 hits PF12157, DUF3591, 1 hit PF09247, TBP-binding, 1 hit PF15288, zf-CCHC_6, 1 hit |
PIRSFi | PIRSF003047, TAF1_animal, 1 hit |
PRINTSi | PR00503, BROMODOMAIN |
SMARTi | View protein in SMART SM00297, BROMO, 2 hits |
SUPFAMi | SSF47055, SSF47055, 1 hit SSF47370, SSF47370, 2 hits |
PROSITEi | View protein in PROSITE PS00633, BROMODOMAIN_1, 2 hits PS50014, BROMODOMAIN_2, 2 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | TAF1_MOUSE | |
Accessioni | Q80UV9Primary (citable) accession number: Q80UV9 Secondary accession number(s): A2AM32 Q9WTX1 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | March 6, 2007 |
Last sequence update: | March 6, 2007 | |
Last modified: | February 10, 2021 | |
This is version 132 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- MGD cross-references
Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot - SIMILARITY comments
Index of protein domains and families