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Entry version 143 (02 Jun 2021)
Sequence version 3 (27 Jul 2011)
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Protein

RIMS-binding protein 2

Gene

Rimbp2

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Plays a role in the synaptic transmission as bifunctional linker that interacts simultaneously with RIMS1, RIMS2, CACNA1D and CACNA1B.

By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
RIMS-binding protein 2
Short name:
RIM-BP2
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Rimbp2
Synonyms:Kiaa0318, Rbp2
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 5

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:2443235, Rimbp2

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cell junction, Cell membrane, Membrane, Synapse

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002213841 – 1072RIMS-binding protein 2Add BLAST1072

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei720PhosphoserineBy similarity1
Modified residuei728PhosphoserineBy similarity1
Modified residuei852PhosphoserineCombined sources1
Modified residuei859PhosphoserineCombined sources1
Modified residuei861PhosphothreonineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q80U40

PRoteomics IDEntifications database

More...
PRIDEi
Q80U40

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
255221 [Q80U40-1]
255222 [Q80U40-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q80U40

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q80U40

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000029420, Expressed in visual cortex and 138 other tissues

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with RIMS1, RIMS2, CACNA1D and CACNA1B, and potentially with other Ca2+ channel alpha-1 isoforms.

By similarity

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
231164, 2 interactors

Protein interaction database and analysis system

More...
IntActi
Q80U40, 1 interactor

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000106978

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q80U40, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q80U40

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini181 – 248SH3 1PROSITE-ProRule annotationAdd BLAST68
Domaini311 – 404Fibronectin type-III 1PROSITE-ProRule annotationAdd BLAST94
Domaini407 – 489Fibronectin type-III 2PROSITE-ProRule annotationAdd BLAST83
Domaini503 – 604Fibronectin type-III 3PROSITE-ProRule annotationAdd BLAST102
Domaini868 – 936SH3 2PROSITE-ProRule annotationAdd BLAST69
Domaini972 – 1039SH3 3PROSITE-ProRule annotationAdd BLAST68

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni597 – 681DisorderedSequence analysisAdd BLAST85
Regioni713 – 800DisorderedSequence analysisAdd BLAST88
Regioni1044 – 1072DisorderedSequence analysisAdd BLAST29

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi598 – 614Pro residuesSequence analysisAdd BLAST17
Compositional biasi619 – 637Basic and acidic residuesSequence analysisAdd BLAST19
Compositional biasi725 – 740Basic and acidic residuesSequence analysisAdd BLAST16
Compositional biasi750 – 770Basic and acidic residuesSequence analysisAdd BLAST21
Compositional biasi1058 – 1072Basic residuesSequence analysisAdd BLAST15

<p>This subsection of the 'Family and domains' section provides general information on the biological role of a domain. The term 'domain' is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

The SH3 domains mediate binding to a proline-rich motif in RIMS1, RIMS2, CACNA1D and CACNA1B.By similarity

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the RIMBP family.Curated

Keywords - Domaini

Repeat, SH3 domain

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3632, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00950000183203

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q80U40

Identification of Orthologs from Complete Genome Data

More...
OMAi
YKQGLGM

Database of Orthologous Groups

More...
OrthoDBi
102427at2759

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00063, FN3, 3 hits
cd12012, SH3_RIM-BP_2, 1 hit
cd12013, SH3_RIM-BP_3, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.40.10, 3 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR003961, FN3_dom
IPR036116, FN3_sf
IPR013783, Ig-like_fold
IPR035519, RIM-BP2
IPR035753, RIM-BP_SH3_2
IPR035755, RIM-BP_SH3_3
IPR040325, RIMBP1/2/3
IPR036028, SH3-like_dom_sf
IPR001452, SH3_domain

The PANTHER Classification System

More...
PANTHERi
PTHR14234, PTHR14234, 2 hits
PTHR14234:SF18, PTHR14234:SF18, 2 hits

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF07653, SH3_2, 1 hit
PF14604, SH3_9, 2 hits

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00452, SH3DOMAIN

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00060, FN3, 3 hits
SM00326, SH3, 3 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF49265, SSF49265, 2 hits
SSF50044, SSF50044, 3 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50853, FN3, 3 hits
PS50002, SH3, 3 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 6 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q80U40-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MREAAERRQQ LELEHEQALA FLNAKQQEIQ LLQQAQVEAK KEHEGAVQLL
60 70 80 90 100
ESKVRELEEK CRVQSEQFNL LSRDLEKFRQ HTGSIDLLGS SSVALLDVPL
110 120 130 140 150
APGKPFPQYM NGLATSIHKG HEGPTGHYSV IGDYIPLSGD KLESPCVKPS
160 170 180 190 200
FLLRSSSPRC RFESEMDNDR NSNNSKQSSS GKVHLCVARY SYNPFDGPNE
210 220 230 240 250
NPEAELPLTA GKYLYVYGDM DEDGFYEGEL LDGQRGLVPS NFVDFIQDNE
260 270 280 290 300
SRLAGTLGSE QDQNFLNHSG ISLERDSILH LHSPTQVDSG ITDNGGGTLD
310 320 330 340 350
VNIDDIGEDT VPYPRKITLI KQLAKSVIVG WEPPAVPPGW GTVSSYNVLV
360 370 380 390 400
DKETRMSLAL GRRTKALIEK LNTAACTYRI SVQCVTSRGN SDELQCTLLV
410 420 430 440 450
GKDVVVAPSQ LRVDNITQIS AQLSWLPTNS NYSHIIFLNE EELDIVKAAR
460 470 480 490 500
YKYQFFNLRP NMAYKVKVLA QPHQMPWQLP LEQREKKEAC VEFSTLPAGP
510 520 530 540 550
PAPPQDVTVH AGATAASVQV SWKPPALTPT GLSNGANVTG YGVYAKGQRV
560 570 580 590 600
AEVIAPTADG TAVELIRLRS LEAKAVSVRT LSVQGESMDS ALAAIPPDLL
610 620 630 640 650
VPPAPHPRTA PPPKPLASDM DTKDQHLGPH VKVDESWEQS RSPGPAHGHM
660 670 680 690 700
LEPPDMHSAG PGRRSPSPSR ILPQPQGAPV STTVAKAMAR EAAQRVAESN
710 720 730 740 750
RLEKRSLFLE QSSAGQYTNS DEEDGYASPE VKRRGTSVDD FLKGSELGKQ
760 770 780 790 800
PHCCHGDEYH TESSRGSDLS DIMEEDEEEL YSEMQLEDGG RRRPSGTSHN
810 820 830 840 850
ALKILGNSTL MGRADRMEHV SRRYSHSGGG SHRHRPAMAP SIDEYTGRDH
860 870 880 890 900
LSPDFYDESE TDPGAEELPA RIFVALFDYD PLTMSPNPDA AEEELPFKEG
910 920 930 940 950
QIIKVYGDKD ADGFYRGETC ARLGLIPCNM VSEIHADDEE MMDQLLRQGF
960 970 980 990 1000
LPLNTPVEKI ERSRRSGRGH SVPTRRMVAL YDYDPRESSP NVDVEAELPF
1010 1020 1030 1040 1050
CTGDIITVFG EIDEDGFYYG ELNGQKGLVP SNFLEEVPDD VEVHLSDAPP
1060 1070
HYSHDPPMRS KAKRKKSVHF TP
Length:1,072
Mass (Da):118,342
Last modified:July 27, 2011 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i462AD1C103A6CA2E
GO
Isoform 2 (identifier: Q80U40-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1065-1072: KKSVHFTP → VSQPP

Show »
Length:1,069
Mass (Da):117,926
Checksum:i478605BCBFD534C9
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
D3YXR8D3YXR8_MOUSE
RIMS-binding protein 2
Rimbp2
1,079Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0G2JFB0A0A0G2JFB0_MOUSE
RIMS-binding protein 2
Rimbp2
1,071Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0G2JGW5A0A0G2JGW5_MOUSE
RIMS-binding protein 2
Rimbp2
1,004Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A571BDA2A0A571BDA2_MOUSE
RIMS-binding protein 2
Rimbp2
1,291Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A5F8MPV6A0A5F8MPV6_MOUSE
RIMS-binding protein 2
Rimbp2
76Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0G2JEC0A0A0G2JEC0_MOUSE
RIMS-binding protein 2
Rimbp2
100Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti76E → Q in AK044685 (PubMed:16141072).Curated1
Sequence conflicti714A → V in AK044685 (PubMed:16141072).Curated1
Sequence conflicti714A → V in BAC65527 (PubMed:12693553).Curated1
Sequence conflicti1065Missing in AK044685 (PubMed:16141072).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0374371065 – 1072KKSVHFTP → VSQPP in isoform 2. 1 Publication8

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK044685 mRNA No translation available.
AC110566 Genomic DNA No translation available.
AC111089 Genomic DNA No translation available.
AC116715 Genomic DNA No translation available.
BC151100 mRNA Translation: AAI51101.1
BC151101 mRNA Translation: AAI51102.1
AK122245 mRNA Translation: BAC65527.2

NCBI Reference Sequences

More...
RefSeqi
NP_001074857.1, NM_001081388.2
NP_001297662.1, NM_001310733.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000199537; ENSMUSP00000143276; ENSMUSG00000029420 [Q80U40-2]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
231760

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:231760

UCSC genome browser

More...
UCSCi
uc008zsk.2, mouse [Q80U40-2]
uc008zsm.1, mouse [Q80U40-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK044685 mRNA No translation available.
AC110566 Genomic DNA No translation available.
AC111089 Genomic DNA No translation available.
AC116715 Genomic DNA No translation available.
BC151100 mRNA Translation: AAI51101.1
BC151101 mRNA Translation: AAI51102.1
AK122245 mRNA Translation: BAC65527.2
RefSeqiNP_001074857.1, NM_001081388.2
NP_001297662.1, NM_001310733.1

3D structure databases

SMRiQ80U40
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi231164, 2 interactors
IntActiQ80U40, 1 interactor
STRINGi10090.ENSMUSP00000106978

PTM databases

iPTMnetiQ80U40
PhosphoSitePlusiQ80U40

Proteomic databases

PaxDbiQ80U40
PRIDEiQ80U40
ProteomicsDBi255221 [Q80U40-1]
255222 [Q80U40-2]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

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Antibodypediai
65349, 44 antibodies

The DNASU plasmid repository

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DNASUi
231760

Genome annotation databases

EnsembliENSMUST00000199537; ENSMUSP00000143276; ENSMUSG00000029420 [Q80U40-2]
GeneIDi231760
KEGGimmu:231760
UCSCiuc008zsk.2, mouse [Q80U40-2]
uc008zsm.1, mouse [Q80U40-1]

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
23504
MGIiMGI:2443235, Rimbp2

Rodent Unidentified Gene-Encoded large proteins database

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Rougei
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Phylogenomic databases

eggNOGiKOG3632, Eukaryota
GeneTreeiENSGT00950000183203
InParanoidiQ80U40
OMAiYKQGLGM
OrthoDBi102427at2759

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

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BioGRID-ORCSi
231760, 2 hits in 52 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
Rimbp2, mouse

Protein Ontology

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PROi
PR:Q80U40
RNActiQ80U40, protein

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSMUSG00000029420, Expressed in visual cortex and 138 other tissues

Family and domain databases

CDDicd00063, FN3, 3 hits
cd12012, SH3_RIM-BP_2, 1 hit
cd12013, SH3_RIM-BP_3, 1 hit
Gene3Di2.60.40.10, 3 hits
InterProiView protein in InterPro
IPR003961, FN3_dom
IPR036116, FN3_sf
IPR013783, Ig-like_fold
IPR035519, RIM-BP2
IPR035753, RIM-BP_SH3_2
IPR035755, RIM-BP_SH3_3
IPR040325, RIMBP1/2/3
IPR036028, SH3-like_dom_sf
IPR001452, SH3_domain
PANTHERiPTHR14234, PTHR14234, 2 hits
PTHR14234:SF18, PTHR14234:SF18, 2 hits
PfamiView protein in Pfam
PF07653, SH3_2, 1 hit
PF14604, SH3_9, 2 hits
PRINTSiPR00452, SH3DOMAIN
SMARTiView protein in SMART
SM00060, FN3, 3 hits
SM00326, SH3, 3 hits
SUPFAMiSSF49265, SSF49265, 2 hits
SSF50044, SSF50044, 3 hits
PROSITEiView protein in PROSITE
PS50853, FN3, 3 hits
PS50002, SH3, 3 hits

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiRIMB2_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q80U40
Secondary accession number(s): B9EKT4, E9QPF5
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 16, 2004
Last sequence update: July 27, 2011
Last modified: June 2, 2021
This is version 143 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Direct protein sequencing, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families
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