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Entry version 96 (26 Feb 2020)
Sequence version 3 (25 Oct 2017)
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Protein

Vacuolar protein sorting-associated protein 13B

Gene

Vps13b

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May be involved in protein sorting in post Golgi membrane traffic.By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processProtein transport, Transport

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Vacuolar protein sorting-associated protein 13B
Alternative name(s):
Cohen syndrome protein 1 homolog
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Vps13b
Synonyms:Coh1, Kiaa0532
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 15

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1916380 Vps13b

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000658811 – 3993Vacuolar protein sorting-associated protein 13BAdd BLAST3993

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei413PhosphoserineBy similarity1
Modified residuei998PhosphoserineBy similarity1
Modified residuei1001PhosphoserineBy similarity1
Modified residuei1032PhosphoserineBy similarity1
Modified residuei1789PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q80TY5

MaxQB - The MaxQuant DataBase

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MaxQBi
Q80TY5

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q80TY5

PRoteomics IDEntifications database

More...
PRIDEi
Q80TY5

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q80TY5

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q80TY5

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Ubiquitously expressed in all examined tissues.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000037646 Expressed in mesenteric lymph node and 242 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q80TY5 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
E9QKX5 MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
578014, 1 interactor

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000045490

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q80TY5 protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the VPS13 family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1809 Eukaryota
COG5043 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000154684

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q80TY5

KEGG Orthology (KO)

More...
KOi
K19526

Identification of Orthologs from Complete Genome Data

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OMAi
QWTIPRI

Database of Orthologous Groups

More...
OrthoDBi
82489at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q80TY5

TreeFam database of animal gene trees

More...
TreeFami
TF323503

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR009543 SHR-BD
IPR031645 VPS13_C
IPR026854 VPS13_N
IPR039782 VPS13B

The PANTHER Classification System

More...
PANTHERi
PTHR12517 PTHR12517, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF12624 Chorein_N, 1 hit
PF06650 SHR-BD, 1 hit
PF16909 VPS13_C, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q80TY5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLESYVTPIL MSYVNRYIKN LKPSDLQLSL WGGDVVLSKL ELKLDVLEQE
60 70 80 90 100
LKLPFTFLSG HIHELRIHVP WTKLGSEPVV ITINTMECIL KLKDGIQDDH
110 120 130 140 150
ESCGSNSTNR STAENTKSSI KPRRIQQAAP ADPDLPPGYV QSLIRRVVNN
160 170 180 190 200
VNIVINNLIL KYVEDDIVLS VNITSAECYT VGELWDRAFM DISATDLVLR
210 220 230 240 250
KAINFSDCTV CLDKRNASGK IEFYQDPLLY KCSFRTRLHF TYDNLNSKMP
260 270 280 290 300
SVIKIHTLVE SLKLSITDQQ LPMFIRIMQL GIALYYGEIG NFKDGETEDP
310 320 330 340 350
PCLSKDTLAN LTGTEEESRI DMQYPAPYKG QELYSQDYEE PQGWVSWAWS
360 370 380 390 400
FVPAIVSYDD GEEDDLGTDP ASIMHQQKAQ TLKDPIVSVG FYCTKATVTF
410 420 430 440 450
KLTEMQAENS YYSPQKVKSK EVLCWEQEGT TIEALMMGEP FFDCQIGFVG
460 470 480 490 500
CRAMCLKGIL GVKDFEEHMN RSETEACFFI CGENLSTKGL TYLTNSLFDY
510 520 530 540 550
RSPENNGTRA EFILDAAHHK ETHTDIAGIQ RFGAFYMDYL YTVEHSSGKG
560 570 580 590 600
PTSQQDFPSG KNEDLGIVQE KSTKSLVIGP LDCRLDSSAV HRVLKMIVCA
610 620 630 640 650
LEHEYEPYSR LKPESKDEKE TVLDPEEVSS LEEYIPTRHT SVTLLKCTCT
660 670 680 690 700
VFMAEFNLLD CLLPVIMGGK NSSNVTNATN FQSLRPLPSI QILVDKINLE
710 720 730 740 750
HSVPMYAEQL VHVVSSLNQP SDNLLHYCYV HCYLKVFGFQ AGLTCLDHSG
760 770 780 790 800
SYCLPAPIIP SFSTALYGKL LKLPALWTKR SQTVVTEGIF ELPNLTIQAT
810 820 830 840 850
RAQTLLLQAI YQSWSHIGNV SSSTVNEALM NEVFPMTGVK SKNPLPTLEG
860 870 880 890 900
SIQNVELKYC STSLVKCASG TLGSIKICAK APGDSGKEKL IPLLQGPSDT
910 920 930 940 950
RDLHSSKWLN ESRKPESLLA PDLIAFTIQV PQYMDYCHHS GAVFLCSVQG
960 970 980 990 1000
LAVNIDPILY TWVIYQPQKR ANRHAQQQPV VAVPLVTSVN RRKEDELSIG
1010 1020 1030 1040 1050
SAPLGKQQSY QASEYASSPI KTKTVTESRP VSVPVKAVLR VHEECRSPED
1060 1070 1080 1090 1100
KMKEFIAILW NAVKSLTLQL DVQSCCVFIP NDNLPSPSTI VSGDIPGTVR
1110 1120 1130 1140 1150
SWYHGQTSIP GTLVLCLPQI KIISAGHKYM EPLQEIPFVI PRPILEEGDA
1160 1170 1180 1190 1200
FPWTISLHHF SIYTLLGKQV TLSLVEPMGC TSTLAVTSQK LLPVGPDGRH
1210 1220 1230 1240 1250
SFVVCLHVDL ESLEIKCSNP QVQLIYELAD TMSKVWSKIQ KRGNLSPSSV
1260 1270 1280 1290 1300
YPETVAGPIP GSPVWSSVGT APPDTSTCSP SADIGTTTEG DSVQAGDDSP
1310 1320 1330 1340 1350
FSDSVTLEQT TSNIGGSSGR VSLWMQWVLP KATVKLFAPD LEKKGTEVCM
1360 1370 1380 1390 1400
VSELEDLSAS IDVQDVYTKV KCKVESFSID HYQSRPGEGW QSGHFEGVFL
1410 1420 1430 1440 1450
QCKEKPVTTT KLLDGAHQQH GFLSLTYTKA VTKNVRHKLT SRNERRSFYK
1460 1470 1480 1490 1500
LSEGLMDGSP HFLHEILLSA QAFDIVVCFP LLNAIASVFH TKLPKTQREK
1510 1520 1530 1540 1550
RKSSGQPMRT HTLTSRNLPL IYINTSVIRI FVPQTEETQS TVAVNQAAKE
1560 1570 1580 1590 1600
DTMVLKVGSI AMAPQADNPL GRSVLRKDIY QKALNLGILR DPGSEIEDRQ
1610 1620 1630 1640 1650
YQIDLQSINI GTAQWDQLKP EKGSGSGGVP TESERNSQNP ALEWNMASSI
1660 1670 1680 1690 1700
QRHQERRAIL TPILTDFSVR ITGAPAIIFT KIISQENLHM EEILVCGHSL
1710 1720 1730 1740 1750
EVNITTNLDF FLSVAQVQLL HQLIVANMTG LEPSTKATEI SKQEQKKVDT
1760 1770 1780 1790 1800
FDGGTAETSS RYSGAQDSGI GSDSVKIRIV QIEQYSGASQ HRIARPSHQS
1810 1820 1830 1840 1850
SIVKNLNFIP FDIFITASRI SLMTYSSVAL PKFKLPEQKE DGKTGRTFLN
1860 1870 1880 1890 1900
LAEVDSDVAK PNQACVSMVT AEDPLSSSTS FSSGKKVRVL SLESLHASTR
1910 1920 1930 1940 1950
SSARQALGVT VVRQPGRRGT GDLELDLFLH LIVSQPSLLL SCHHRKQRVE
1960 1970 1980 1990 2000
VSIFDAMLKG VPSDYTCTDP GKTLPEASDY NIVWLQTVPG ETDSKSGIPP
2010 2020 2030 2040 2050
SLVTLHIKDF LNGPADIYLD VSKPLKANLS FTKLDQINHF LKKIKKAHSS
2060 2070 2080 2090 2100
AHSKETSTPS DSILNMDEPP VPKCYRGKLS KTKVHCDEAQ KTSFQENIWR
2110 2120 2130 2140 2150
AISCFQKVSV HTTQIVVSME TVPHPHKPCV LASLSNLNGS LTVKAAQKVP
2160 2170 2180 2190 2200
GASLGSSFLL SIHDVLLKTS LKERSRILIG PFSATVNLEA KWCKHSGNPG
2210 2220 2230 2240 2250
PQQSIPKISM DLRGGLLQVF WGQEHLNCLA LLHELFNGYL QEGKSEMPVP
2260 2270 2280 2290 2300
ESAPQMPSPV EKTQAFKTEQ SSDDLRTGIF QYVQDAESLK LPGVYEVLFY
2310 2320 2330 2340 2350
NETEESPGMM LWRYPEPRVL TLVRITPVPF NTTEDPDIST ADLGDVLQVP
2360 2370 2380 2390 2400
CGLEYWDELQ KVFVAFQEFS LSESKVCELQ LPDINLVHDQ KKLVSSDLWR
2410 2420 2430 2440 2450
IVLNNNQNTT DDQSSASESG SQSTCEPLVT PTALAACTRV DSCFTPWFVP
2460 2470 2480 2490 2500
SLCMSFQFAH LEFRLCHHLD QLGTASPQYL QPFISDKNVP SELEYMIISF
2510 2520 2530 2540 2550
REPNLHLRQW NSGPVCQEIK FSSQMDCKLL ECRNVTMQTV VKPFGICGQM
2560 2570 2580 2590 2600
ALSSDGVQKL LDSTVIVDSV LVNFGQHVVH SLNTAIQAWQ QNKCPEVEEL
2610 2620 2630 2640 2650
VFSHFVICND TQETLRFGQV DTDENILLAS LHSHQYSWRS HKSPQLLHIC
2660 2670 2680 2690 2700
IEGWGNWRWS EPFTVDHAGT FIRTIQYKGR TASLIIKVRA LSGVQKQIII
2710 2720 2730 2740 2750
CGRQIICSYL SQSIELKVVQ HYIGQDGQAV VREHFDCLTA KQKLPSYILE
2760 2770 2780 2790 2800
NNELTELCVK AKGDEDWSRD VCLEPKASEY STVIQVPTSN SSIIYVWCTV
2810 2820 2830 2840 2850
LTLEPNSQVQ QRMIVFSPLF IMRSHLPDPI IIHLEKRSLG LSETQIIPGR
2860 2870 2880 2890 2900
GQENPLQNVE PDLVHHLTFQ AREEYDPSDC AVPISTALIK QIATKIQPGG
2910 2920 2930 2940 2950
TVNEMLDEFY GPEKSQEPTW PYSNKDSDRN EQLSQWDSPM RVKLSIWKPY
2960 2970 2980 2990 3000
VRTLLIELLP WALLINQSKW DLWLFEGEKI VLQVPAGKII IPPNFQEAFQ
3010 3020 3030 3040 3050
IGIYWENTNT VHKTLAIKLV HNLTSPKWKD GGNGEVVTLD EEAFVDAEIR
3060 3070 3080 3090 3100
LGAFPGHQKL CQFCISSMVQ HGIQVIQIED KTTVINNTPY QIVYKPHLAI
3110 3120 3130 3140 3150
SNSYSGKEHC HVPDSATFSI CPGGEHPAVR SSSLPCWDVT PAVGSSELDT
3160 3170 3180 3190 3200
ATLQKQILLG FSPVPGADSA QCWSLPAIIG GEFPRQSVAV PFGTGRENGF
3210 3220 3230 3240 3250
CTRAIALTYQ EHLGVTYITL SEDPSPRVVF HNRCPVPMLM KENIRDIPKF
3260 3270 3280 3290 3300
DVYCKKIPPE SSVHHELYHQ IISYPDCKTK DLLPSLFLRI DSMEEMTAEW
3310 3320 3330 3340 3350
SDPVDINSQG TQVVFLTGFG YVYVDIAQQC GTVFIILAPE GKAGPIFTST
3360 3370 3380 3390 3400
SRALERMVTF RMFITQLSLA VSDDLTHQAP SELLRLTLDN VFLHVSPVPA
3410 3420 3430 3440 3450
LLPGEEPPSS FFQLYGVEVY CGDLQLDNQL YNKSNFHFAV LVCQGERTDP
3460 3470 3480 3490 3500
AQYSRVQSLL VSSKALEEYK ENCFIKLCLT VSEGKDILLD VSEFTFELKP
3510 3520 3530 3540 3550
ARLYVEDTFV YYIKTLFDTY LPPSRMSGHH AQLFTGQQVL PVQVTQHAKA
3560 3570 3580 3590 3600
LVNAVKLRKL LIQPVNLLIS IHASLKLYIA SDHTPLSFSV FERGPVFTTA
3610 3620 3630 3640 3650
RQLVHALAMH YAAGALFRAG WVVGSLEILG SPASLVRSIG NGISDFFRLP
3660 3670 3680 3690 3700
YEGLTRGPGA FVSGVSRGTT SFVKHISKGA LTSITNLATS LARNMGRLSL
3710 3720 3730 3740 3750
DEEHYNRQEE WRRQLPESLG EGLRQGLSRL GISLLGAIAG IVDQPMQNFQ
3760 3770 3780 3790 3800
KTSETQASAG HKAKGVISGV GKGIMGVFTK PIGGAAELVS QTGYGILHGA
3810 3820 3830 3840 3850
GLSQLPKQRC QPTHLYADQA PNSHVKYVWK MLQSLGRPEV HMALDVVLVR
3860 3870 3880 3890 3900
GSGQEHEGCL LLTSEVLFVV SISEDTQQQA FPITEISCAQ DTKQNNLLTV
3910 3920 3930 3940 3950
QLKQPRVASD VEIDGARERL SEQQFKRLVD YIAKTSCHLA PSCSSMQTCS
3960 3970 3980 3990
VVAVEPPPAT VKTYHYLVDP HFAQVFISKF TMVKNKALRK GFS
Length:3,993
Mass (Da):444,015
Last modified:October 25, 2017 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i91DF61575D20A990
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A2I3BPN3A0A2I3BPN3_MOUSE
Vacuolar protein sorting-associated...
Vps13b
46Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti2402V → I in BAC65584 (PubMed:12693553).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC121598 Genomic DNA No translation available.
AC122241 Genomic DNA No translation available.
AC144772 Genomic DNA No translation available.
AC157521 Genomic DNA No translation available.
AC166356 Genomic DNA No translation available.
AK122302 mRNA Translation: BAC65584.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS49592.1

NCBI Reference Sequences

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RefSeqi
NP_796125.2, NM_177151.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000048646; ENSMUSP00000045490; ENSMUSG00000037646

Database of genes from NCBI RefSeq genomes

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GeneIDi
666173

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:666173

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC121598 Genomic DNA No translation available.
AC122241 Genomic DNA No translation available.
AC144772 Genomic DNA No translation available.
AC157521 Genomic DNA No translation available.
AC166356 Genomic DNA No translation available.
AK122302 mRNA Translation: BAC65584.1
CCDSiCCDS49592.1
RefSeqiNP_796125.2, NM_177151.3

3D structure databases

Database of comparative protein structure models

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ModBasei
Search...

SWISS-MODEL Interactive Workspace

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SWISS-MODEL-Workspacei
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Protein-protein interaction databases

BioGridi578014, 1 interactor
STRINGi10090.ENSMUSP00000045490

PTM databases

iPTMnetiQ80TY5
PhosphoSitePlusiQ80TY5

Proteomic databases

jPOSTiQ80TY5
MaxQBiQ80TY5
PaxDbiQ80TY5
PRIDEiQ80TY5

Genome annotation databases

EnsembliENSMUST00000048646; ENSMUSP00000045490; ENSMUSG00000037646
GeneIDi666173
KEGGimmu:666173

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
157680
MGIiMGI:1916380 Vps13b

Rodent Unidentified Gene-Encoded large proteins database

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Rougei
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Phylogenomic databases

eggNOGiKOG1809 Eukaryota
COG5043 LUCA
GeneTreeiENSGT00940000154684
InParanoidiQ80TY5
KOiK19526
OMAiQWTIPRI
OrthoDBi82489at2759
PhylomeDBiQ80TY5
TreeFamiTF323503

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
Vps13b mouse

Protein Ontology

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PROi
PR:Q80TY5
RNActiQ80TY5 protein

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSMUSG00000037646 Expressed in mesenteric lymph node and 242 other tissues
ExpressionAtlasiQ80TY5 baseline and differential
GenevisibleiE9QKX5 MM

Family and domain databases

InterProiView protein in InterPro
IPR009543 SHR-BD
IPR031645 VPS13_C
IPR026854 VPS13_N
IPR039782 VPS13B
PANTHERiPTHR12517 PTHR12517, 1 hit
PfamiView protein in Pfam
PF12624 Chorein_N, 1 hit
PF06650 SHR-BD, 1 hit
PF16909 VPS13_C, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiVP13B_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q80TY5
Secondary accession number(s): E9QKX5
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 16, 2004
Last sequence update: October 25, 2017
Last modified: February 26, 2020
This is version 96 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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