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Entry version 129 (07 Apr 2021)
Sequence version 2 (07 Jun 2004)
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Protein

R3H domain-containing protein 2

Gene

R3hdm2

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
R3H domain-containing protein 2
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:R3hdm2
Synonyms:Kiaa1002
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 10

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1919000, R3hdm2

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000507881 – 1044R3H domain-containing protein 2Add BLAST1044

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei37PhosphoserineBy similarity1
Modified residuei143PhosphoserineCombined sources1
Modified residuei362PhosphoserineBy similarity1
Modified residuei365PhosphoserineCombined sources1
Modified residuei381PhosphoserineBy similarity1
Modified residuei921PhosphoserineBy similarity1
Modified residuei923PhosphoserineBy similarity1
Modified residuei924PhosphothreonineCombined sources1
Modified residuei928PhosphothreonineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q80TM6

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q80TM6

PeptideAtlas

More...
PeptideAtlasi
Q80TM6

PRoteomics IDEntifications database

More...
PRIDEi
Q80TM6

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
253136 [Q80TM6-1]
253137 [Q80TM6-2]
253138 [Q80TM6-3]
253139 [Q80TM6-4]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q80TM6

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q80TM6

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000025404, Expressed in zygote and 252 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q80TM6, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
214898, 3 interactors

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000128659

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q80TM6, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Biological Magnetic Resonance Data Bank

More...
BMRBi
Q80TM6

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q80TM6

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini169 – 232R3HPROSITE-ProRule annotationAdd BLAST64
Domaini233 – 303SUZPROSITE-ProRule annotationAdd BLAST71

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi320 – 323Poly-Ser4
Compositional biasi436 – 447Poly-GlnAdd BLAST12

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2953, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000155609

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_007817_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q80TM6

Identification of Orthologs from Complete Genome Data

More...
OMAi
VDIIQLH

Database of Orthologous Groups

More...
OrthoDBi
137913at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q80TM6

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.30.1370.50, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001374, R3H_dom
IPR036867, R3H_dom_sf
IPR024771, SUZ

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01424, R3H, 1 hit
PF12752, SUZ, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00393, R3H, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF82708, SSF82708, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51061, R3H, 1 hit
PS51673, SUZ, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (4+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 4 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 4 described isoforms and 11 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q80TM6-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MSNSNTTQET LEIMKESEKK LVEESVNKNK FISKTPSKED VEKEGEENGL
60 70 80 90 100
RQETQRRTSS HGHARKRAKS NSKLKLVRSL AVCEESSTPF VDGPLDTQDI
110 120 130 140 150
IQLHISCPSD KEEEKSTKDV SEKEDKDKSK EKVPRKMLSR DSSQEYTDST
160 170 180 190 200
GIDLHEFLVN TLKKNPRDRM MLLKLEQEIL DFINDNNNQF KKFPQMTSYH
210 220 230 240 250
RMLLHRVAAY FGMDHNVDQT GKAVIINKTS STRIPEQRFS EHIKDEKNTE
260 270 280 290 300
FQQRFILKRD DASMDRDDNQ MRVPLQDGRR SKSIEEREEE YQRVRERIFA
310 320 330 340 350
RETGQNGYLN DIRLSKEAFS SSSHKRRQIF RGNREGLSRT SSSRQSSTDS
360 370 380 390 400
ELKSLEPRPW SSTDSDGSVR SMRPPVTKAS SFSGISILTR GDSIGSSKGG
410 420 430 440 450
SAGRLSRPGM ALGAPEVCNQ VTSPQSVRGL LPCTAQQQQQ QQQQQQQLPA
460 470 480 490 500
LPPTPQHQPP LNNHMISQPV PALQPSPQPV QFSPSSCPQV LLPVSPPQQY
510 520 530 540 550
NMAEDLSNPF GQMSLSRQGS TEAADPSSAL FQPPLISQHP QQASFIMASA
560 570 580 590 600
GQPLPTSNYS TSSHAPPTQQ VLPPQGYMQP PQQIQVSYYP PGQYPNSNQQ
610 620 630 640 650
YRPLSHPVAY SPQRGQQLPQ ASQQPGLQPM MSNQQQTAYQ GMLGVQQPQN
660 670 680 690 700
QGLLSNQRSS MGGQMQGLVV QYTPLPSYQV PVGSDSQNVV QPSFQQPMLV
710 720 730 740 750
PASQSVQGGL PTGGVPVYYS MIPPAQQNGT SPSVGFLQPP GSEQYQMPQS
760 770 780 790 800
PSPCSPPQMS QQYSGVSPSG PGVVVMQLNV PNGPQAPQNP SMVQWSHCKY
810 820 830 840 850
YSVEQRGQKP GDLYSPDGSP QANAQMGSSP VTSPTQSPAP SPVTSLSNVC
860 870 880 890 900
TGLSPLPVLT PFPRPGGPAQ GDGRYSLLGQ PLQYNLSICP PLLHGQSTYT
910 920 930 940 950
VHQGQSGLKH GNRGKRQALK SASTDLGTAD VVLGRVLEVT DLPEGITRTE
960 970 980 990 1000
ADKLFTQLAM SGAKIQWLKD AQGLPGAGGG DNSGTAENGR HPDLAALYTI
1010 1020 1030 1040
VAVFPSPLAA QNASLRLNNS VSRFKLRVAK KNYDLRILER ASSQ
Length:1,044
Mass (Da):114,583
Last modified:June 7, 2004 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i529D97E3E3EBEFBE
GO
Isoform 2 (identifier: Q80TM6-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     313-330: Missing.
     469-502: Missing.

Show »
Length:992
Mass (Da):108,796
Checksum:i3AB825C12B332982
GO
Isoform 3 (identifier: Q80TM6-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     313-330: Missing.

Show »
Length:1,026
Mass (Da):112,437
Checksum:iA4F153BD44DD7333
GO
Isoform 4 (identifier: Q80TM6-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     271-302: Missing.
     490-502: Missing.

Show »
Length:999
Mass (Da):109,084
Checksum:i97358C49C4E5517A
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 11 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
E9Q9D6E9Q9D6_MOUSE
R3H domain-containing protein 2
R3hdm2
978Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q148X5Q148X5_MOUSE
R3H domain-containing protein 2
R3hdm2
1,012Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F6Z9T5F6Z9T5_MOUSE
R3H domain-containing protein 2
R3hdm2
743Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E9PX98E9PX98_MOUSE
R3H domain-containing protein 2
R3hdm2
27Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E9Q013E9Q013_MOUSE
R3H domain-containing protein 2
R3hdm2
98Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E9Q0F6E9Q0F6_MOUSE
R3H domain-containing protein 2
R3hdm2
102Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F6QRV2F6QRV2_MOUSE
R3H domain-containing protein 2
R3hdm2
154Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F6WY86F6WY86_MOUSE
R3H domain-containing protein 2
R3hdm2
264Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F6TDX7F6TDX7_MOUSE
R3H domain-containing protein 2
R3hdm2
91Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E9PZ57E9PZ57_MOUSE
R3H domain-containing protein 2
R3hdm2
62Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
There is more potential isoformShow all

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AK043545 differs from that shown. Reason: Frameshift.Curated
The sequence BAB23642 differs from that shown. Reason: Erroneous initiation.Curated
The sequence BAC65698 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti28K → R in AK043545 (PubMed:16141072).Curated1
Sequence conflicti964K → T in AK043545 (PubMed:16141072).Curated1
Sequence conflicti1015L → I in AK043545 (PubMed:16141072).Curated1
Sequence conflicti1029A → D in AK043545 (PubMed:16141072).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_010555271 – 302Missing in isoform 4. 1 PublicationAdd BLAST32
Alternative sequenceiVSP_010553313 – 330Missing in isoform 2 and isoform 3. 2 PublicationsAdd BLAST18
Alternative sequenceiVSP_010554469 – 502Missing in isoform 2. 2 PublicationsAdd BLAST34
Alternative sequenceiVSP_010556490 – 502Missing in isoform 4. 1 PublicationAdd BLAST13

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK122416 mRNA Translation: BAC65698.1 Different initiation.
AK004884 mRNA Translation: BAB23642.2 Different initiation.
AK043545 mRNA No translation available.
BC043083 mRNA Translation: AAH43083.1
BC064442 mRNA Translation: AAH64442.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS24241.1 [Q80TM6-4]
CCDS48717.1 [Q80TM6-1]
CCDS88102.1 [Q80TM6-3]

NCBI Reference Sequences

More...
RefSeqi
NP_001161764.1, NM_001168292.1 [Q80TM6-1]
NP_082176.4, NM_027900.4 [Q80TM6-4]
XP_006514215.1, XM_006514152.2 [Q80TM6-1]
XP_006514216.1, XM_006514153.2 [Q80TM6-1]
XP_006514217.1, XM_006514154.3 [Q80TM6-1]
XP_006514218.1, XM_006514155.3
XP_006514219.1, XM_006514156.3 [Q80TM6-1]
XP_006514220.1, XM_006514157.2 [Q80TM6-1]
XP_006514221.1, XM_006514158.2 [Q80TM6-3]
XP_006514225.1, XM_006514162.2 [Q80TM6-2]
XP_017169592.1, XM_017314103.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000064793; ENSMUSP00000069724; ENSMUSG00000025404 [Q80TM6-4]
ENSMUST00000077046; ENSMUSP00000076303; ENSMUSG00000025404 [Q80TM6-1]
ENSMUST00000105249; ENSMUSP00000100884; ENSMUSG00000025404 [Q80TM6-2]
ENSMUST00000105250; ENSMUSP00000100885; ENSMUSG00000025404 [Q80TM6-3]
ENSMUST00000105251; ENSMUSP00000100886; ENSMUSG00000025404 [Q80TM6-3]
ENSMUST00000166820; ENSMUSP00000126608; ENSMUSG00000025404 [Q80TM6-1]

Database of genes from NCBI RefSeq genomes

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GeneIDi
71750

KEGG: Kyoto Encyclopedia of Genes and Genomes

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KEGGi
mmu:71750

UCSC genome browser

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UCSCi
uc007hjl.2, mouse [Q80TM6-1]
uc007hjm.2, mouse [Q80TM6-4]
uc007hjo.2, mouse [Q80TM6-3]
uc007hjp.2, mouse [Q80TM6-2]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK122416 mRNA Translation: BAC65698.1 Different initiation.
AK004884 mRNA Translation: BAB23642.2 Different initiation.
AK043545 mRNA No translation available.
BC043083 mRNA Translation: AAH43083.1
BC064442 mRNA Translation: AAH64442.1
CCDSiCCDS24241.1 [Q80TM6-4]
CCDS48717.1 [Q80TM6-1]
CCDS88102.1 [Q80TM6-3]
RefSeqiNP_001161764.1, NM_001168292.1 [Q80TM6-1]
NP_082176.4, NM_027900.4 [Q80TM6-4]
XP_006514215.1, XM_006514152.2 [Q80TM6-1]
XP_006514216.1, XM_006514153.2 [Q80TM6-1]
XP_006514217.1, XM_006514154.3 [Q80TM6-1]
XP_006514218.1, XM_006514155.3
XP_006514219.1, XM_006514156.3 [Q80TM6-1]
XP_006514220.1, XM_006514157.2 [Q80TM6-1]
XP_006514221.1, XM_006514158.2 [Q80TM6-3]
XP_006514225.1, XM_006514162.2 [Q80TM6-2]
XP_017169592.1, XM_017314103.1

3D structure databases

BMRBiQ80TM6
SMRiQ80TM6
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi214898, 3 interactors
STRINGi10090.ENSMUSP00000128659

PTM databases

iPTMnetiQ80TM6
PhosphoSitePlusiQ80TM6

Proteomic databases

jPOSTiQ80TM6
PaxDbiQ80TM6
PeptideAtlasiQ80TM6
PRIDEiQ80TM6
ProteomicsDBi253136 [Q80TM6-1]
253137 [Q80TM6-2]
253138 [Q80TM6-3]
253139 [Q80TM6-4]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

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Antibodypediai
28556, 51 antibodies

Genome annotation databases

EnsembliENSMUST00000064793; ENSMUSP00000069724; ENSMUSG00000025404 [Q80TM6-4]
ENSMUST00000077046; ENSMUSP00000076303; ENSMUSG00000025404 [Q80TM6-1]
ENSMUST00000105249; ENSMUSP00000100884; ENSMUSG00000025404 [Q80TM6-2]
ENSMUST00000105250; ENSMUSP00000100885; ENSMUSG00000025404 [Q80TM6-3]
ENSMUST00000105251; ENSMUSP00000100886; ENSMUSG00000025404 [Q80TM6-3]
ENSMUST00000166820; ENSMUSP00000126608; ENSMUSG00000025404 [Q80TM6-1]
GeneIDi71750
KEGGimmu:71750
UCSCiuc007hjl.2, mouse [Q80TM6-1]
uc007hjm.2, mouse [Q80TM6-4]
uc007hjo.2, mouse [Q80TM6-3]
uc007hjp.2, mouse [Q80TM6-2]

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
22864
MGIiMGI:1919000, R3hdm2

Rodent Unidentified Gene-Encoded large proteins database

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Rougei
Search...

Phylogenomic databases

eggNOGiKOG2953, Eukaryota
GeneTreeiENSGT00940000155609
HOGENOMiCLU_007817_0_0_1
InParanoidiQ80TM6
OMAiVDIIQLH
OrthoDBi137913at2759
PhylomeDBiQ80TM6

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

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BioGRID-ORCSi
71750, 0 hits in 13 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
R3hdm2, mouse

Protein Ontology

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PROi
PR:Q80TM6
RNActiQ80TM6, protein

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000025404, Expressed in zygote and 252 other tissues
GenevisibleiQ80TM6, MM

Family and domain databases

Gene3Di3.30.1370.50, 1 hit
InterProiView protein in InterPro
IPR001374, R3H_dom
IPR036867, R3H_dom_sf
IPR024771, SUZ
PfamiView protein in Pfam
PF01424, R3H, 1 hit
PF12752, SUZ, 1 hit
SMARTiView protein in SMART
SM00393, R3H, 1 hit
SUPFAMiSSF82708, SSF82708, 1 hit
PROSITEiView protein in PROSITE
PS51061, R3H, 1 hit
PS51673, SUZ, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiR3HD2_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q80TM6
Secondary accession number(s): Q80YB1, Q8BLS5, Q9CW50
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 7, 2004
Last sequence update: June 7, 2004
Last modified: April 7, 2021
This is version 129 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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