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Entry version 124 (02 Jun 2021)
Sequence version 1 (01 Jun 2003)
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Protein

ADAMTS-like protein 4

Gene

Adamtsl4

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Positive regulation of apoptosis. May facilitate FBN1 microfibril biogenesis (By similarity).

By similarity

Caution

Although similar to members of the ADAMTS family, it lacks the metalloprotease and disintegrin-like domains which are typical of that family.Curated

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processApoptosis

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-MMU-5173214, O-glycosylation of TSR domain-containing proteins

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
ADAMTS-like protein 4
Short name:
ADAMTSL-4
Alternative name(s):
Thrombospondin repeat-containing protein 1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Adamtsl4Imported
Synonyms:Tsrc1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:2389008, Adamtsl4

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Extracellular matrix, Secreted

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 24Sequence analysisAdd BLAST24
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000025796725 – 1036ADAMTS-like protein 4Sequence analysisAdd BLAST1012

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi454N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi737N-linked (GlcNAc...) asparagineSequence analysis1

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

Glycosylated (By similarity). Can be O-fucosylated by POFUT2 on a serine or a threonine residue found within the consensus sequence C1-X2-(S/T)-C2-G of the TSP type-1 repeat domains where C1 and C2 are the first and second cysteine residue of the repeat, respectively. Fucosylated repeats can then be further glycosylated by the addition of a beta-1,3-glucose residue by the glucosyltransferase, B3GALTL. Fucosylation mediates the efficient secretion of ADAMTS family members. Also can be C-glycosylated with one or two mannose molecules on tryptophan residues within the consensus sequence W-X-X-W of the TPRs, and N-glycosylated. These other glycosylations can also facilitate secretion (By similarity).By similarity

Keywords - PTMi

Glycoprotein

Proteomic databases

The CPTAC Assay portal

More...
CPTACi
non-CPTAC-3560

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q80T21

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q80T21

PeptideAtlas

More...
PeptideAtlasi
Q80T21

PRoteomics IDEntifications database

More...
PRIDEi
Q80T21

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
265150

PTM databases

GlyGen: Computational and Informatics Resources for Glycoscience

More...
GlyGeni
Q80T21, 2 sites

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q80T21

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q80T21

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Widely expressed in a range of tissues. Especially prevalent in brain, spinal cord, muscle, lung and heart.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000015850, Expressed in heart left ventricle and 200 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q80T21, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with CTSB.

Interacts with FBN1 (By similarity).

By similarity

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
230868, 3 interactors

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000015994

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q80T21, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q80T21

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini47 – 91TSP type-1 1PROSITE-ProRule annotationAdd BLAST45
Domaini687 – 748TSP type-1 2PROSITE-ProRule annotationAdd BLAST62
Domaini750 – 804TSP type-1 3PROSITE-ProRule annotationAdd BLAST55
Domaini805 – 871TSP type-1 4PROSITE-ProRule annotationAdd BLAST67
Domaini872 – 931TSP type-1 5PROSITE-ProRule annotationAdd BLAST60
Domaini932 – 988TSP type-1 6PROSITE-ProRule annotationAdd BLAST57
Domaini991 – 1028PLACPROSITE-ProRule annotationAdd BLAST38

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni73 – 149DisorderedSequence analysisAdd BLAST77
Regioni163 – 308DisorderedSequence analysisAdd BLAST146

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi174 – 194Polar residuesSequence analysisAdd BLAST21
Compositional biasi211 – 251Polar residuesSequence analysisAdd BLAST41

Keywords - Domaini

Repeat, Signal

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3538, Eukaryota
KOG4597, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000161136

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_000660_6_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q80T21

Identification of Orthologs from Complete Genome Data

More...
OMAi
QICNTIP

Database of Orthologous Groups

More...
OrthoDBi
414258at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q80T21

TreeFam database of animal gene trees

More...
TreeFami
TF316874

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.20.100.10, 6 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR010294, ADAM_spacer1
IPR010909, PLAC
IPR000884, TSP1_rpt
IPR036383, TSP1_rpt_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF05986, ADAM_spacer1, 1 hit
PF08686, PLAC, 1 hit
PF00090, TSP_1, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00209, TSP1, 7 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF82895, SSF82895, 6 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50900, PLAC, 1 hit
PS50092, TSP1, 6 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q80T21-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MESWLGRLWL CMMLLLPLPQ PCQDQELFGP SHQLPSEEGQ VPEGLWGPWG
60 70 80 90 100
RWASCSQPCG VGVQRRSRTC ELHPALPLPP RPPRHPEAHR PRGQGSRPQT
110 120 130 140 150
PRDPQSLYRP QPRGRGGPLR APASQVGREE TQEPQGAQRF RVRDPIKPGM
160 170 180 190 200
FGYGRVPFAL PLHRSRRHPH RPGQPKNSST GEGMVPSQPP STELASEKHG
210 220 230 240 250
PHMQPPEPRS HSAETPRSGT AQTEVLPRTS SAPSYTGTPA PTSSFGDSRS
260 270 280 290 300
FQGSLGPRMP PSPGSWSSPQ GAERRHPPPF SPVPRSQQSR RHWRPPGPHR
310 320 330 340 350
SPDGWLPLTR DSSPLWSIFA PSIPAPNCSG ESEQMRACSQ EPCPPEQPDP
360 370 380 390 400
RALQCAAFDS QEFMGQLYQW EPFTEVQGSQ RCELNCRPRG FRFYVRHTEK
410 420 430 440 450
VQDGTLCQPG SLDICVAGRC LSPGCDGVLG SGRRPDGCGV CGGDGSTCRL
460 470 480 490 500
VSGNLTDRGG PLGYQKILWI PAGASHLHIS QLRPSSNYLA LRGPGGRSII
510 520 530 540 550
NGNWAVDPPG SYTAIGTVFQ YNRPPREEGK GESLSAEGPT TQPVDVYMIF
560 570 580 590 600
QEDNPGVFYQ YVISSPPAVL ESPSTKPPAL QPQPEMLRGE PLLPSAPRPV
610 620 630 640 650
RAPGTLQRQV RIPQVPPPTR VRTAMGSSAG YWKQVGHSEC SASCGKGVWH
660 670 680 690 700
PIFLCISRES GEELDEQSCA VGARPPASPE PCHGPPCPPY WEAGEWTSCS
710 720 730 740 750
RSCGPGTQHR QLLCRQEFGG GGSSVPPERC GHLPRPNITQ PCQLHLCGHW
760 770 780 790 800
EISSPWSQCS VRCGRGQRSR QVRCVGSNGD EVDKQECASG PPPPPSREAC
810 820 830 840 850
DMGPCTTAWF YSDWSSKCSA ECGTGIQRRA VVCLRSGETL QGDPEAGSTE
860 870 880 890 900
QGCPLRSRPP DMRACSLGPC ERTWRWFTGP WSECSSECGS GTQHRDIICV
910 920 930 940 950
SKLGAEFNVT SPSNCSHLPR PPALQPCQGQ ACEDKWFSTL WSPCSRSCQG
960 970 980 990 1000
GMQTREVQCL SGNQTLSSRC PPHLRPSRKR PCNSQPCNQR PDDQCKDSSP
1010 1020 1030
HCPLVVQARL CVYPYYTTTC CRSCAHVLEQ SQLEPA
Length:1,036
Mass (Da):113,225
Last modified:June 1, 2003 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iF018D59E71018714
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
D3Z0T6D3Z0T6_MOUSE
ADAMTS-like protein 4
Adamtsl4
70Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti93G → R in AAI17926 (PubMed:15489334).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AY158701 mRNA Translation: AAO17738.1
BC117925 mRNA Translation: AAI17926.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS17618.1

NCBI Reference Sequences

More...
RefSeqi
NP_001288634.1, NM_001301705.1
NP_659148.2, NM_144899.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000015994; ENSMUSP00000015994; ENSMUSG00000015850
ENSMUST00000117782; ENSMUSP00000113424; ENSMUSG00000015850

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
229595

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:229595

UCSC genome browser

More...
UCSCi
uc008qkm.2, mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY158701 mRNA Translation: AAO17738.1
BC117925 mRNA Translation: AAI17926.1
CCDSiCCDS17618.1
RefSeqiNP_001288634.1, NM_001301705.1
NP_659148.2, NM_144899.3

3D structure databases

SMRiQ80T21
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi230868, 3 interactors
STRINGi10090.ENSMUSP00000015994

PTM databases

GlyGeniQ80T21, 2 sites
iPTMnetiQ80T21
PhosphoSitePlusiQ80T21

Proteomic databases

CPTACinon-CPTAC-3560
MaxQBiQ80T21
PaxDbiQ80T21
PeptideAtlasiQ80T21
PRIDEiQ80T21
ProteomicsDBi265150

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
1665, 93 antibodies

The DNASU plasmid repository

More...
DNASUi
229595

Genome annotation databases

EnsembliENSMUST00000015994; ENSMUSP00000015994; ENSMUSG00000015850
ENSMUST00000117782; ENSMUSP00000113424; ENSMUSG00000015850
GeneIDi229595
KEGGimmu:229595
UCSCiuc008qkm.2, mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
54507
MGIiMGI:2389008, Adamtsl4

Phylogenomic databases

eggNOGiKOG3538, Eukaryota
KOG4597, Eukaryota
GeneTreeiENSGT00940000161136
HOGENOMiCLU_000660_6_0_1
InParanoidiQ80T21
OMAiQICNTIP
OrthoDBi414258at2759
PhylomeDBiQ80T21
TreeFamiTF316874

Enzyme and pathway databases

ReactomeiR-MMU-5173214, O-glycosylation of TSR domain-containing proteins

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
229595, 5 hits in 52 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Adamtsl4, mouse

Protein Ontology

More...
PROi
PR:Q80T21
RNActiQ80T21, protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000015850, Expressed in heart left ventricle and 200 other tissues
GenevisibleiQ80T21, MM

Family and domain databases

Gene3Di2.20.100.10, 6 hits
InterProiView protein in InterPro
IPR010294, ADAM_spacer1
IPR010909, PLAC
IPR000884, TSP1_rpt
IPR036383, TSP1_rpt_sf
PfamiView protein in Pfam
PF05986, ADAM_spacer1, 1 hit
PF08686, PLAC, 1 hit
PF00090, TSP_1, 1 hit
SMARTiView protein in SMART
SM00209, TSP1, 7 hits
SUPFAMiSSF82895, SSF82895, 6 hits
PROSITEiView protein in PROSITE
PS50900, PLAC, 1 hit
PS50092, TSP1, 6 hits

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiATL4_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q80T21
Secondary accession number(s): Q148X6
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: June 1, 2003
Last modified: June 2, 2021
This is version 124 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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