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Protein

Alpha-1,4 glucan phosphorylase

Gene
N/A
Organism
Gallus gallus (Chicken)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.UniRule annotation

Catalytic activityi

((1->4)-alpha-D-glucosyl)(n) + phosphate = ((1->4)-alpha-D-glucosyl)(n-1) + alpha-D-glucose 1-phosphate.UniRule annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosyltransferaseUniRule annotationImported, Transferase
Biological processCarbohydrate metabolismUniRule annotation
LigandPyridoxal phosphateUniRule annotation

Enzyme and pathway databases

BRENDAi2.4.1.1 1306

Protein family/group databases

CAZyiGT35 Glycosyltransferase Family 35

Names & Taxonomyi

Protein namesi
Recommended name:
Alpha-1,4 glucan phosphorylaseUniRule annotation (EC:2.4.1.1UniRule annotation)
OrganismiGallus gallus (Chicken)Imported
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei681N6-(pyridoxal phosphate)lysineUniRule annotation1

Structurei

3D structure databases

ProteinModelPortaliQ7ZZK3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycogen phosphorylase family.UniRule annotation

Phylogenomic databases

eggNOGiKOG2099 Eukaryota
COG0058 LUCA
HOVERGENiHBG006848
KOiK00688

Family and domain databases

CDDicd04300 GT1_Glycogen_Phosphorylase, 1 hit
InterProiView protein in InterPro
IPR011833 Glycg_phsphrylas
IPR000811 Glyco_trans_35
IPR035090 Pyridoxal_P_attach_site
PANTHERiPTHR11468 PTHR11468, 1 hit
PfamiView protein in Pfam
PF00343 Phosphorylase, 1 hit
PIRSFiPIRSF000460 Pprylas_GlgP, 1 hit
TIGRFAMsiTIGR02093 P_ylase, 1 hit
PROSITEiView protein in PROSITE
PS00102 PHOSPHORYLASE, 1 hit

Sequencei

Sequence statusi: Complete.

Q7ZZK3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSRPLSDQER RKQISIRGIV GAENVAELKR GFNRHLHFTL VKDRNVATPR
60 70 80 90 100
DYYFALAHTV RDHLVGRWIR TQQYYYERDP KRIYYLSLEF YMGRTLQNTM
110 120 130 140 150
INLGLQNACD EAVYQLGLDI EELEEIEEDA GLGNGGLGRL AACFLDSMAT
160 170 180 190 200
LGLAAYGYGI RYEYGIFNQK IRNGWQVEEA DDWLRHGNPW EKARPEYMLP
210 220 230 240 250
VHFYGRVEHT ANGTKWADTQ VVLALPYDTP VPGYMNNTVN TMRLWSARAP
260 270 280 290 300
NDFNLRDFNV GDYIQAVLDR NLAENISRVL YPNDNFFEGK ELRLKQEYFV
310 320 330 340 350
VAATLQDIIR RFKASKFGST ESVRTVFDSF PDQVAIQLND THPAMAIPEL
360 370 380 390 400
MRIFVDIEKL PWSKAWDITK QTFAYTNHTV LPEALERWPV DLVEKLLPRH
410 420 430 440 450
LEIIYEINQR HLDHIAFLFP NDVDRLRRMS LIEEGGTKRI NMAHLCIVGS
460 470 480 490 500
HAVNGVAKIH SEIVKSEVFR DFAELEPDKF QNKTNGITPR RWLLLCNPGL
510 520 530 540 550
AELIAEKIGE DYVRDLSQLA KLHEFVDDDL FIREVAKVKQ ENKVKFALYL
560 570 580 590 600
EKEYKVKINP SSMFDVHVKR IHEYKRQLMN CLHIITMYNR IKRDPVKLFV
610 620 630 640 650
PRTVIIGGKA APGYHMAKMI IKLINAVAQV VNNDPVVGSK LKVIFLENYR
660 670 680 690 700
VSLAEKVIPA TDLSEQISTA GTEASGTGNM KFMLNGALTI GTMDGANVEM
710 720 730 740 750
AEEAGEENLF IFGMRVEDVA ELDKDGYNAQ QYYDRLPELK QAVDQIRSGF
760 770 780 790 800
FSSDEPDLFR DVVDMLFHHD RFKVFADYEA YVKCQEKVSE LYLNSKAWTK
810 820 830 840 850
MVIRNMAAAG KFSSDRTIKE YARDIWHVEP SDLKIPPPNE PREGAEDRTP

NGTAARA
Length:857
Mass (Da):98,566
Last modified:June 1, 2003 - v1
Checksum:i52AEC95D4FA997BE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY271349 mRNA Translation: AAP33020.1
RefSeqiNP_989723.1, NM_204392.1
UniGeneiGga.7031

Genome annotation databases

GeneIDi378909
KEGGigga:378909

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY271349 mRNA Translation: AAP33020.1
RefSeqiNP_989723.1, NM_204392.1
UniGeneiGga.7031

3D structure databases

ProteinModelPortaliQ7ZZK3
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

CAZyiGT35 Glycosyltransferase Family 35

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi378909
KEGGigga:378909

Organism-specific databases

CTDi5836

Phylogenomic databases

eggNOGiKOG2099 Eukaryota
COG0058 LUCA
HOVERGENiHBG006848
KOiK00688

Enzyme and pathway databases

BRENDAi2.4.1.1 1306

Family and domain databases

CDDicd04300 GT1_Glycogen_Phosphorylase, 1 hit
InterProiView protein in InterPro
IPR011833 Glycg_phsphrylas
IPR000811 Glyco_trans_35
IPR035090 Pyridoxal_P_attach_site
PANTHERiPTHR11468 PTHR11468, 1 hit
PfamiView protein in Pfam
PF00343 Phosphorylase, 1 hit
PIRSFiPIRSF000460 Pprylas_GlgP, 1 hit
TIGRFAMsiTIGR02093 P_ylase, 1 hit
PROSITEiView protein in PROSITE
PS00102 PHOSPHORYLASE, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiQ7ZZK3_CHICK
AccessioniPrimary (citable) accession number: Q7ZZK3
Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: June 1, 2003
Last modified: February 28, 2018
This is version 82 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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