UniProtKB - Q7ZWJ4 (RL18A_DANRE)
Protein
60S ribosomal protein L18a
Gene
rpl18a
Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Functioni
GO - Molecular functioni
- structural constituent of ribosome Source: InterPro
GO - Biological processi
- translation Source: InterPro
Keywordsi
Molecular function | Ribonucleoprotein, Ribosomal protein |
Enzyme and pathway databases
Reactomei | R-DRE-156827, L13a-mediated translational silencing of Ceruloplasmin expression R-DRE-1799339, SRP-dependent cotranslational protein targeting to membrane R-DRE-6791226, Major pathway of rRNA processing in the nucleolus and cytosol R-DRE-72706, GTP hydrolysis and joining of the 60S ribosomal subunit R-DRE-975956, Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-DRE-975957, Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) |
Names & Taxonomyi
Protein namesi | Recommended name: 60S ribosomal protein L18a |
Gene namesi | Name:rpl18a ORF Names:zgc:56546 |
Organismi | Danio rerio (Zebrafish) (Brachydanio rerio) |
Taxonomic identifieri | 7955 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Ostariophysi › Cypriniformes › Danionidae › Danioninae › Danio |
Proteomesi |
|
Organism-specific databases
ZFINi | ZDB-GENE-040426-1071, rpl18a |
Subcellular locationi
Cytosol
- cytosolic large ribosomal subunit Source: GO_Central
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000213928 | 1 – 176 | 60S ribosomal protein L18aAdd BLAST | 176 |
Proteomic databases
PaxDbi | Q7ZWJ4 |
PRIDEi | Q7ZWJ4 |
Expressioni
Gene expression databases
Bgeei | ENSDARG00000025073, Expressed in brain and 35 other tissues |
ExpressionAtlasi | Q7ZWJ4, baseline |
Family & Domainsi
Sequence similaritiesi
Belongs to the eukaryotic ribosomal protein eL20 family.Curated
Phylogenomic databases
eggNOGi | KOG0829, Eukaryota |
GeneTreei | ENSGT00390000015797 |
HOGENOMi | CLU_080773_2_0_1 |
InParanoidi | Q7ZWJ4 |
OMAi | RFWYFMK |
OrthoDBi | 1265349at2759 |
PhylomeDBi | Q7ZWJ4 |
TreeFami | TF300086 |
Family and domain databases
HAMAPi | MF_00273, Ribosomal_L18Ae, 1 hit |
InterProi | View protein in InterPro IPR028877, 50S_L18Ae/Ribosomal_L18a/L20 IPR023573, Ribosomal_L18a//L18Ae/LX IPR021138, Ribosomal_L18a/L20_eukaryotes |
PANTHERi | PTHR10052, PTHR10052, 1 hit |
Pfami | View protein in Pfam PF01775, Ribosomal_L18A, 1 hit |
PIRSFi | PIRSF002190, Ribosomal_L18a, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All
Q7ZWJ4-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MKASGTLREY KVVGRLLPSV KNPAPPLYRM RIFAPNHVVA KSRFWYFVSQ
60 70 80 90 100
LRKMKKASGE IVYCGLVFEK SPLKVKNFGI WLRYDSRSGT HNMYREYRDL
110 120 130 140 150
TTSGAVTQCY RDMGARHRAR AHAIQIMKVQ VIAANKCRRP AIKQFHDSKI
160 170
KFPLPHRVLR RQHKPRFTTK RPNTFF
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketF8W484 | F8W484_DANRE | 60S ribosomal protein L18a | rpl18a | 76 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL928834 Genomic DNA Translation: CAI12012.1 BX890562 Genomic DNA Translation: CAK04577.1 BC049045 mRNA Translation: AAH49045.1 |
RefSeqi | NP_957354.1, NM_201060.1 |
Genome annotation databases
Ensembli | ENSDART00000030215; ENSDARP00000038658; ENSDARG00000025073 |
GeneIDi | 394035 |
KEGGi | dre:394035 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL928834 Genomic DNA Translation: CAI12012.1 BX890562 Genomic DNA Translation: CAK04577.1 BC049045 mRNA Translation: AAH49045.1 |
RefSeqi | NP_957354.1, NM_201060.1 |
3D structure databases
SMRi | Q7ZWJ4 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 7955.ENSDARP00000038658 |
Proteomic databases
PaxDbi | Q7ZWJ4 |
PRIDEi | Q7ZWJ4 |
Genome annotation databases
Ensembli | ENSDART00000030215; ENSDARP00000038658; ENSDARG00000025073 |
GeneIDi | 394035 |
KEGGi | dre:394035 |
Organism-specific databases
CTDi | 6142 |
ZFINi | ZDB-GENE-040426-1071, rpl18a |
Phylogenomic databases
eggNOGi | KOG0829, Eukaryota |
GeneTreei | ENSGT00390000015797 |
HOGENOMi | CLU_080773_2_0_1 |
InParanoidi | Q7ZWJ4 |
OMAi | RFWYFMK |
OrthoDBi | 1265349at2759 |
PhylomeDBi | Q7ZWJ4 |
TreeFami | TF300086 |
Enzyme and pathway databases
Reactomei | R-DRE-156827, L13a-mediated translational silencing of Ceruloplasmin expression R-DRE-1799339, SRP-dependent cotranslational protein targeting to membrane R-DRE-6791226, Major pathway of rRNA processing in the nucleolus and cytosol R-DRE-72706, GTP hydrolysis and joining of the 60S ribosomal subunit R-DRE-975956, Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-DRE-975957, Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) |
Miscellaneous databases
PROi | PR:Q7ZWJ4 |
Gene expression databases
Bgeei | ENSDARG00000025073, Expressed in brain and 35 other tissues |
ExpressionAtlasi | Q7ZWJ4, baseline |
Family and domain databases
HAMAPi | MF_00273, Ribosomal_L18Ae, 1 hit |
InterProi | View protein in InterPro IPR028877, 50S_L18Ae/Ribosomal_L18a/L20 IPR023573, Ribosomal_L18a//L18Ae/LX IPR021138, Ribosomal_L18a/L20_eukaryotes |
PANTHERi | PTHR10052, PTHR10052, 1 hit |
Pfami | View protein in Pfam PF01775, Ribosomal_L18A, 1 hit |
PIRSFi | PIRSF002190, Ribosomal_L18a, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | RL18A_DANRE | |
Accessioni | Q7ZWJ4Primary (citable) accession number: Q7ZWJ4 Secondary accession number(s): Q1LVB1 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | July 19, 2005 |
Last sequence update: | June 1, 2003 | |
Last modified: | December 2, 2020 | |
This is version 95 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families - Ribosomal proteins
Ribosomal proteins families and list of entries