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UniProtKB - Q7ZW46 (S35B4_DANRE)
Protein
UDP-xylose and UDP-N-acetylglucosamine transporter
Gene
slc35b4
Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Functioni
Sugar transporter that specifically mediates the transport of UDP-xylose (UDP-Xyl) and UDP-N-acetylglucosamine (UDP-GlcNAc) from cytosol into Golgi.
By similarityGO - Molecular functioni
- transmembrane transporter activity Source: GO_Central
- UDP-N-acetylglucosamine transmembrane transporter activity Source: GO_Central
- UDP-xylose transmembrane transporter activity Source: GO_Central
GO - Biological processi
- carbohydrate transport Source: UniProtKB-KW
Keywordsi
Biological process | Sugar transport, Transport |
Enzyme and pathway databases
Reactomei | R-DRE-727802, Transport of nucleotide sugars |
Names & Taxonomyi
Protein namesi | Recommended name: UDP-xylose and UDP-N-acetylglucosamine transporterAlternative name(s): Solute carrier family 35 member B4 |
Gene namesi | Name:slc35b4 ORF Names:zgc:55288 |
Organismi | Danio rerio (Zebrafish) (Brachydanio rerio) |
Taxonomic identifieri | 7955 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Ostariophysi › Cypriniformes › Danionidae › Danioninae › Danio |
Proteomesi |
|
Organism-specific databases
ZFINi | ZDB-GENE-030131-2457, slc35b4 |
Subcellular locationi
Golgi apparatus
- Golgi apparatus membrane By similarity; Multi-pass membrane protein By similarity
Endoplasmic reticulum
- integral component of endoplasmic reticulum membrane Source: GO_Central
Golgi apparatus
- integral component of Golgi membrane Source: GO_Central
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 5 – 25 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 30 – 50 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 59 – 79 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 92 – 112 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 122 – 142 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 153 – 173 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 201 – 221 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 238 – 260 | HelicalSequence analysisAdd BLAST | 23 | |
Transmembranei | 267 – 289 | HelicalSequence analysisAdd BLAST | 23 | |
Transmembranei | 301 – 321 | HelicalSequence analysisAdd BLAST | 21 |
Keywords - Cellular componenti
Golgi apparatus, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000213389 | 1 – 331 | UDP-xylose and UDP-N-acetylglucosamine transporterAdd BLAST | 331 |
Proteomic databases
PaxDbi | Q7ZW46 |
Family & Domainsi
Sequence similaritiesi
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | KOG1583, Eukaryota |
InParanoidi | Q7ZW46 |
PhylomeDBi | Q7ZW46 |
Family and domain databases
InterProi | View protein in InterPro IPR013657, UAA |
PANTHERi | PTHR10778, PTHR10778, 1 hit |
Pfami | View protein in Pfam PF08449, UAA, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All
Q7ZW46-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MNTLFAVTLV FVGCCSNVVF LELLVRDFPG CGNIVTFAQF AFIALEGFIF
60 70 80 90 100
ETNFGRKKPQ IPLSNYVIMV TMFFTVSVIN NYALDFNIAM PLHMIFRSGS
110 120 130 140 150
LIANMILGII ILKNRYSMSK YLSIVLVSVG IFICTIMSAK QVNVEKGGTE
160 170 180 190 200
EDGVYAFMHW LLGIAMLTFA LLMSARMGIF QETLYKKYGK HSKEALFYNH
210 220 230 240 250
CLPLPGFLLL STNIYNHAVL FSQSPPMEVP VIGLSMPVMW FYLLMNVITQ
260 270 280 290 300
YVCIRGVFIL TTECASLTVT LVVTLRKFLS LIISILYFQN PFTAWHWVGT
310 320 330
AVVFLGTLLY TEVLSSIPAA FKGYKVDKKA E
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketF1Q9W9 | F1Q9W9_DANRE | UDP-xylose and UDP-N-acetylglucosam... | slc35b4 | 331 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC045293 mRNA Translation: AAH45293.1 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC045293 mRNA Translation: AAH45293.1 |
3D structure databases
SMRi | Q7ZW46 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 7955.ENSDARP00000095658 |
Proteomic databases
PaxDbi | Q7ZW46 |
Organism-specific databases
ZFINi | ZDB-GENE-030131-2457, slc35b4 |
Phylogenomic databases
eggNOGi | KOG1583, Eukaryota |
InParanoidi | Q7ZW46 |
PhylomeDBi | Q7ZW46 |
Enzyme and pathway databases
Reactomei | R-DRE-727802, Transport of nucleotide sugars |
Miscellaneous databases
PROi | PR:Q7ZW46 |
Family and domain databases
InterProi | View protein in InterPro IPR013657, UAA |
PANTHERi | PTHR10778, PTHR10778, 1 hit |
Pfami | View protein in Pfam PF08449, UAA, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | S35B4_DANRE | |
Accessioni | Q7ZW46Primary (citable) accession number: Q7ZW46 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | November 22, 2005 |
Last sequence update: | June 1, 2003 | |
Last modified: | February 23, 2022 | |
This is version 84 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families