UniProtKB - Q7ZUR2 (Q7ZUR2_DANRE)
Protein
Submitted name:
Ubiquitin-conjugating enzyme E2D 3
Gene
ube2d3
Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Functioni
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Active sitei | 85 | Glycyl thioester intermediatePROSITE-ProRule annotation | 1 |
GO - Molecular functioni
- ATP binding Source: UniProtKB-UniRule
- ubiquitin conjugating enzyme activity Source: GO_Central
- ubiquitin protein ligase binding Source: GO_Central
GO - Biological processi
- protein K48-linked ubiquitination Source: GO_Central
- protein polyubiquitination Source: GO_Central
- ubiquitin-dependent protein catabolic process Source: GO_Central
Keywordsi
Molecular function | TransferaseARBA annotation |
Biological process | Ubl conjugation pathwayUniRule annotationARBA annotation |
Ligand | ATP-bindingUniRule annotation, Nucleotide-binding |
Names & Taxonomyi
Protein namesi | Submitted name: Ubiquitin-conjugating enzyme E2D 3ImportedSubmitted name: Zgc:56340Imported |
Gene namesi | |
Organismi | Danio rerio (Zebrafish) (Brachydanio rerio)Imported |
Taxonomic identifieri | 7955 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Ostariophysi › Cypriniformes › Danionidae › Danioninae › Danio |
Proteomesi |
|
Organism-specific databases
ZFINi | ZDB-GENE-030131-551, ube2d3 |
Subcellular locationi
Nucleus
- nucleus Source: GO_Central
Other locations
- ubiquitin ligase complex Source: GO_Central
Expressioni
Gene expression databases
Bgeei | ENSDARG00000038473, Expressed in muscle tissue and 38 other tissues |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 4 – 136 | UBC coreInterPro annotationAdd BLAST | 133 |
Sequence similaritiesi
Belongs to the ubiquitin-conjugating enzyme family.UniRule annotation
Phylogenomic databases
GeneTreei | ENSGT00940000153169 |
HOGENOMi | CLU_030988_13_3_1 |
Family and domain databases
CDDi | cd00195, UBCc, 1 hit |
Gene3Di | 3.10.110.10, 1 hit |
InterProi | View protein in InterPro IPR000608, UBQ-conjugat_E2 IPR023313, UBQ-conjugating_AS IPR016135, UBQ-conjugating_enzyme/RWD |
Pfami | View protein in Pfam PF00179, UQ_con, 1 hit |
SUPFAMi | SSF54495, SSF54495, 1 hit |
PROSITEi | View protein in PROSITE PS00183, UBIQUITIN_CONJUGAT_1, 1 hit PS50127, UBIQUITIN_CONJUGAT_2, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All
Q7ZUR2-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MALKRIQKEL TDLARDPPAQ CSAGPVGDDV FHWQATIMGP NESPYQGGVF
60 70 80 90 100
FLTIHFPTDY PFKPPKVAFT TRIYHPNINS NGSICLDILR SQWSPALTIS
110 120 130 140
KVLLSICSLL CDPNPDDPLV PEIARIYKTD TEKYNRIARE WTQKYAM
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketA9JRT4 | A9JRT4_DANRE | Ubiquitin-conjugating enzyme E2D 3 | ube2d3 zgc:56340 | 148 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CR559945 Genomic DNA No translation available. BC047863 mRNA Translation: AAH47863.1 |
RefSeqi | NP_955865.1, NM_199571.1 |
Genome annotation databases
Ensembli | ENSDART00000187819; ENSDARP00000150757; ENSDARG00000038473 |
GeneIDi | 321832 |
KEGGi | dre:321832 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CR559945 Genomic DNA No translation available. BC047863 mRNA Translation: AAH47863.1 |
RefSeqi | NP_955865.1, NM_199571.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Genome annotation databases
Ensembli | ENSDART00000187819; ENSDARP00000150757; ENSDARG00000038473 |
GeneIDi | 321832 |
KEGGi | dre:321832 |
Organism-specific databases
CTDi | 7323 |
ZFINi | ZDB-GENE-030131-551, ube2d3 |
Phylogenomic databases
GeneTreei | ENSGT00940000153169 |
HOGENOMi | CLU_030988_13_3_1 |
Gene expression databases
Bgeei | ENSDARG00000038473, Expressed in muscle tissue and 38 other tissues |
Family and domain databases
CDDi | cd00195, UBCc, 1 hit |
Gene3Di | 3.10.110.10, 1 hit |
InterProi | View protein in InterPro IPR000608, UBQ-conjugat_E2 IPR023313, UBQ-conjugating_AS IPR016135, UBQ-conjugating_enzyme/RWD |
Pfami | View protein in Pfam PF00179, UQ_con, 1 hit |
SUPFAMi | SSF54495, SSF54495, 1 hit |
PROSITEi | View protein in PROSITE PS00183, UBIQUITIN_CONJUGAT_1, 1 hit PS50127, UBIQUITIN_CONJUGAT_2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q7ZUR2_DANRE | |
Accessioni | Q7ZUR2Primary (citable) accession number: Q7ZUR2 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | June 1, 2003 |
Last sequence update: | June 1, 2003 | |
Last modified: | December 2, 2020 | |
This is version 137 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |