UniProtKB - Q7ZU55 (Q7ZU55_DANRE)
Protein
Submitted name:
C-terminal binding protein 1
Gene
ctbp1
Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Functioni
GO - Molecular functioni
- NAD binding Source: InterPro
- oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor Source: InterPro
- transcription corepressor activity Source: InterPro
GO - Biological processi
- retinoic acid receptor signaling pathway Source: ZFIN
Keywordsi
Molecular function | OxidoreductaseUniRule annotationARBA annotation |
Names & Taxonomyi
Protein namesi | Submitted name: C-terminal binding protein 1Imported |
Gene namesi | Name:ctbp1Imported |
Organismi | Danio rerio (Zebrafish) (Brachydanio rerio)Imported |
Taxonomic identifieri | 7955 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Ostariophysi › Cypriniformes › Danionidae › Danioninae › Danio |
Organism-specific databases
ZFINi | ZDB-GENE-010130-1, ctbp1 |
Subcellular locationi
Keywords - Cellular componenti
NucleusARBA annotationFamily & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 44 – 358 | 2-Hacid_dhInterPro annotationAdd BLAST | 315 | |
Domaini | 139 – 322 | 2-Hacid_dh_CInterPro annotationAdd BLAST | 184 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 422 – 449 | DisorderedSequence analysisAdd BLAST | 28 |
Sequence similaritiesi
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.UniRule annotationARBA annotation
Phylogenomic databases
OrthoDBi | 700058at2759 |
Family and domain databases
CDDi | cd05299, CtBP_dh, 1 hit |
InterProi | View protein in InterPro IPR043322, CtBP IPR006139, D-isomer_2_OHA_DH_cat_dom IPR029753, D-isomer_DH_CS IPR029752, D-isomer_DH_CS1 IPR006140, D-isomer_DH_NAD-bd IPR036291, NAD(P)-bd_dom_sf |
Pfami | View protein in Pfam PF00389, 2-Hacid_dh, 1 hit PF02826, 2-Hacid_dh_C, 1 hit |
SUPFAMi | SSF51735, SSF51735, 1 hit |
PROSITEi | View protein in PROSITE PS00065, D_2_HYDROXYACID_DH_1, 1 hit PS00671, D_2_HYDROXYACID_DH_3, 1 hit |
i Sequence
Sequence statusi: Complete.
Q7ZU55-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MALMDKHKVK RQRLDRICEG IRPPILNGPM HPRPLVALLD GRDCTVEMPI
60 70 80 90 100
LKDVATVAFC DAQSTQEIHE KVLNEAVAAL LYHTITLSRD DLDKFKGLRV
110 120 130 140 150
IVRIGSGFDN VDIKAAAELG IAVCNVPAAS VEETADTAMC LILNLYRRVT
160 170 180 190 200
WMHQALREGT RASSVEQIRE VAGGAARIRG ETLGIIGLGR VGQAVALRAK
210 220 230 240 250
AFGFGVIFYD PYLPNGVERS LGLQRMATLQ DLLMHSDCVS LHCSLNEHNH
260 270 280 290 300
HLINDFTIRQ MRQGAFLVNT ARGGLVDEKA LAQALKEGRI RGAALDVHET
310 320 330 340 350
EPFSFSQGPL KDAPNLICTP HTSWYSEQAS IEAREEAARE VRRAITGRIP
360 370 380 390 400
DSLKNCVNKE YLMAASQWPS MEATTVHSEL NGAAAYRFPA GLIGVAAGGL
410 420 430 440
PGAGAGVEGI VAGSLPLAHA IAPVSHPPHT PSPGQPSKAE ADRDIPSDQ
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC045280 mRNA Translation: AAH45280.1 |
RefSeqi | NP_571789.2, NM_131714.2 |
Genome annotation databases
GeneIDi | 65229 |
KEGGi | dre:65229 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC045280 mRNA Translation: AAH45280.1 |
RefSeqi | NP_571789.2, NM_131714.2 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Genome annotation databases
GeneIDi | 65229 |
KEGGi | dre:65229 |
Organism-specific databases
CTDi | 1487 |
ZFINi | ZDB-GENE-010130-1, ctbp1 |
Phylogenomic databases
OrthoDBi | 700058at2759 |
Family and domain databases
CDDi | cd05299, CtBP_dh, 1 hit |
InterProi | View protein in InterPro IPR043322, CtBP IPR006139, D-isomer_2_OHA_DH_cat_dom IPR029753, D-isomer_DH_CS IPR029752, D-isomer_DH_CS1 IPR006140, D-isomer_DH_NAD-bd IPR036291, NAD(P)-bd_dom_sf |
Pfami | View protein in Pfam PF00389, 2-Hacid_dh, 1 hit PF02826, 2-Hacid_dh_C, 1 hit |
SUPFAMi | SSF51735, SSF51735, 1 hit |
PROSITEi | View protein in PROSITE PS00065, D_2_HYDROXYACID_DH_1, 1 hit PS00671, D_2_HYDROXYACID_DH_3, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q7ZU55_DANRE | |
Accessioni | Q7ZU55Primary (citable) accession number: Q7ZU55 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | June 1, 2003 |
Last sequence update: | June 1, 2003 | |
Last modified: | December 2, 2020 | |
This is version 105 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |