UniProtKB - Q7ZTL7 (BCS1_XENLA)
Protein
Mitochondrial chaperone BCS1
Gene
bcs1l
Organism
Xenopus laevis (African clawed frog)
Status
Functioni
Chaperone necessary for the assembly of mitochondrial respiratory chain complex III.By similarity
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Nucleotide bindingi | 230 – 237 | ATPSequence analysis | 8 |
GO - Molecular functioni
- ATPase activity Source: InterPro
- ATP binding Source: UniProtKB-KW
Keywordsi
Molecular function | Chaperone |
Ligand | ATP-binding, Nucleotide-binding |
Names & Taxonomyi
Protein namesi | Recommended name: Mitochondrial chaperone BCS1Alternative name(s): BCS1-like protein |
Gene namesi | Name:bcs1l |
Organismi | Xenopus laevis (African clawed frog) |
Taxonomic identifieri | 8355 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Amphibia › Batrachia › Anura › Pipoidea › Pipidae › Xenopodinae › Xenopus › Xenopus |
Organism-specific databases
Xenbasei | XB-GENE-1015032, bcs1l.L |
Subcellular locationi
Mitochondrion
- Mitochondrion inner membrane By similarity; Single-pass membrane protein By similarity
Mitochondrion
- mitochondrial inner membrane Source: UniProtKB-SubCell
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 1 – 15 | Mitochondrial intermembraneSequence analysisAdd BLAST | 15 | |
Transmembranei | 16 – 32 | HelicalSequence analysisAdd BLAST | 17 | |
Topological domaini | 33 – 419 | Mitochondrial matrixSequence analysisAdd BLAST | 387 |
Keywords - Cellular componenti
Membrane, Mitochondrion, Mitochondrion inner membranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000084775 | 1 – 419 | Mitochondrial chaperone BCS1Add BLAST | 419 |
Family & Domainsi
Sequence similaritiesi
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
OrthoDBi | 532729at2759 |
Family and domain databases
InterProi | View protein in InterPro IPR003593, AAA+_ATPase IPR003959, ATPase_AAA_core IPR003960, ATPase_AAA_CS IPR014851, BCS1_N IPR027417, P-loop_NTPase |
Pfami | View protein in Pfam PF00004, AAA, 1 hit PF08740, BCS1_N, 1 hit |
SMARTi | View protein in SMART SM00382, AAA, 1 hit SM01024, BCS1_N, 1 hit |
SUPFAMi | SSF52540, SSF52540, 1 hit |
PROSITEi | View protein in PROSITE PS00674, AAA, 1 hit |
i Sequence
Sequence statusi: Complete.
Q7ZTL7-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MPFADFVAAL KDNPYFGAGF GLVGVGTALA LTRKGAQFGM IAFRRHYMIT
60 70 80 90 100
LEVPSKDKSY QWLLSWISHY AKNTQHLSVE TSYLQHESGR ISTKFDFVPS
110 120 130 140 150
PGNHFIWYRS KWIRIERNRE KQMIDLHTGT PWESVTFTAL GTNRNIFFNI
160 170 180 190 200
LQEARELALK QQVGKTVMYN AVGAEWRQFG FPRRRRPLSS VVLEQGISEK
210 220 230 240 250
IVQDVKGFIE NPKWYSDRGI PYRRGYLLYG PPGCGKSSFI TALAGELEYS
260 270 280 290 300
ICLMSLSDSS LSDDRLNHLL SVAPQQSIIL LEDVDAAFVS RDLNKQNPTA
310 320 330 340 350
YQGMGRLTFS GLLNALDGVA STEARIVFMT TNHIDRLDPA LIRPGRVDVK
360 370 380 390 400
QYVGHCTNWQ LSQMFLRFYP DQTAGQSEAF ASAALSSSDK ISAAQVQGHF
410
MMHKTDPDGA IQNVCLATM
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC045021 mRNA Translation: AAH45021.1 |
RefSeqi | NP_001080674.1, NM_001087205.1 |
Genome annotation databases
GeneIDi | 380366 |
KEGGi | xla:380366 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC045021 mRNA Translation: AAH45021.1 |
RefSeqi | NP_001080674.1, NM_001087205.1 |
3D structure databases
SMRi | Q7ZTL7 |
ModBasei | Search... |
Genome annotation databases
GeneIDi | 380366 |
KEGGi | xla:380366 |
Organism-specific databases
CTDi | 380366 |
Xenbasei | XB-GENE-1015032, bcs1l.L |
Phylogenomic databases
OrthoDBi | 532729at2759 |
Family and domain databases
InterProi | View protein in InterPro IPR003593, AAA+_ATPase IPR003959, ATPase_AAA_core IPR003960, ATPase_AAA_CS IPR014851, BCS1_N IPR027417, P-loop_NTPase |
Pfami | View protein in Pfam PF00004, AAA, 1 hit PF08740, BCS1_N, 1 hit |
SMARTi | View protein in SMART SM00382, AAA, 1 hit SM01024, BCS1_N, 1 hit |
SUPFAMi | SSF52540, SSF52540, 1 hit |
PROSITEi | View protein in PROSITE PS00674, AAA, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | BCS1_XENLA | |
Accessioni | Q7ZTL7Primary (citable) accession number: Q7ZTL7 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | April 13, 2004 |
Last sequence update: | June 1, 2003 | |
Last modified: | December 2, 2020 | |
This is version 80 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program |