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UniProtKB - Q7Z9I0 (YHA8_SCHPO)
Protein
Uncharacterized MFS-type transporter SPBC409.08
Gene
SPBC409.08
Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Functioni
GO - Molecular functioni
- spermine transmembrane transporter activity Source: PomBase
- xenobiotic transmembrane transporter activity Source: GO_Central
GO - Biological processi
- spermine transmembrane transport Source: PomBase
- xenobiotic detoxification by transmembrane export across the plasma membrane Source: GO_Central
Keywordsi
Biological process | Transport |
Protein family/group databases
TCDBi | 2.A.1.2.108, the major facilitator superfamily (mfs) |
Names & Taxonomyi
Protein namesi | Recommended name: Uncharacterized MFS-type transporter SPBC409.08 |
Gene namesi | ORF Names:SPBC409.08 |
Organismi | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) |
Taxonomic identifieri | 284812 [NCBI] |
Taxonomic lineagei | Eukaryota › Fungi › Dikarya › Ascomycota › Taphrinomycotina › Schizosaccharomycetes › Schizosaccharomycetales › Schizosaccharomycetaceae › Schizosaccharomyces › |
Proteomesi |
|
Organism-specific databases
PomBasei | SPBC409.08 |
Subcellular locationi
Other locations
- Membrane Sequence analysis; Multi-pass membrane protein Sequence analysis
Plasma Membrane
- plasma membrane Source: PomBase
Vacuole
- fungal-type vacuole membrane Source: GO_Central
Other locations
- integral component of membrane Source: GO_Central
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 116 – 136 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 158 – 178 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 181 – 201 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 203 – 223 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 238 – 258 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 271 – 291 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 345 – 365 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 383 – 403 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 424 – 444 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 450 – 470 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 484 – 506 | HelicalSequence analysisAdd BLAST | 23 | |
Transmembranei | 519 – 539 | HelicalSequence analysisAdd BLAST | 21 |
Keywords - Cellular componenti
MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000372711 | 1 – 552 | Uncharacterized MFS-type transporter SPBC409.08Add BLAST | 552 |
Proteomic databases
PaxDbi | Q7Z9I0 |
Interactioni
Protein-protein interaction databases
BioGRIDi | 277530, 7 interactors |
STRINGi | 4896.SPBC409.08.1 |
Structurei
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 59 | DisorderedSequence analysisAdd BLAST | 59 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 1 – 16 | Basic and acidic residuesSequence analysisAdd BLAST | 16 | |
Compositional biasi | 17 – 59 | Polar residuesSequence analysisAdd BLAST | 43 |
Sequence similaritiesi
Belongs to the major facilitator superfamily.Sequence analysis
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | KOG0255, Eukaryota |
HOGENOMi | CLU_008455_11_5_1 |
InParanoidi | Q7Z9I0 |
Family and domain databases
Gene3Di | 1.20.1250.20, 1 hit |
InterProi | View protein in InterPro IPR011701, MFS IPR020846, MFS_dom IPR036259, MFS_trans_sf IPR005829, Sugar_transporter_CS |
Pfami | View protein in Pfam PF07690, MFS_1, 1 hit |
SUPFAMi | SSF103473, SSF103473, 1 hit |
PROSITEi | View protein in PROSITE PS50850, MFS, 1 hit |
i Sequence
Sequence statusi: Complete.
Q7Z9I0-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MPLEKTNTHD STATVEDQEA TDNPMHLTQS RMLDLAGNPN RTTSRQSETL
60 70 80 90 100
FPNGVDLNYP FTTTRGPPDV AEYNLETAEG VYRDPTINEG EEELVTWELN
110 120 130 140 150
DPENPHNWSR LWKWYITIVN SLLVVCSAFG SSVIAGDLED VSRDLKVGPE
160 170 180 190 200
VANLSCSLMV VGFGIGPLVI SPLSEMIGRR IVYLVTLMIY IVLQIPCALA
210 220 230 240 250
PNIACLLIVR FFCGCFGCTP LTLAGGVISD VWETRERGLA IAFFAAGPYA
260 270 280 290 300
GPTLGPLVGG WIGVGTGDFR WIFWVNMIYM FVMYLTLLPV PETYAPVLLR
310 320 330 340 350
WRAQRIRKET GRQVFTAQEK QMLSFKEIVQ VNLTRPLTLL LTEPILVCIS
360 370 380 390 400
GYIALIYALL YGYFFAYPNV FVKGKGYNEG ITGLMFIPIL VGVVGALSTT
410 420 430 440 450
PFLEKQYMAK LDANNGKSVP EWRLVGMCIA SPFIPTGLLI FAWTSFPRLI
460 470 480 490 500
WIGPAFSGAP FGYGMVLFYF SANNYLIDVY QNYCASALAA KTMVRSAGGA
510 520 530 540 550
AFPLFIDYMM DGMTRQWAFF LLGMVAVAAI PIPFTFYLFG DKIRARSKAA
IV
Sequence cautioni
The sequence CAB52610 differs from that shown. Reason: Erroneous gene model prediction.Curated
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CU329671 Genomic DNA Translation: CAB52610.2 Sequence problems. |
RefSeqi | NP_595458.1, NM_001021368.2 |
Genome annotation databases
EnsemblFungii | SPBC409.08.1; SPBC409.08.1:pep; SPBC409.08 |
GeneIDi | 2541015 |
KEGGi | spo:SPBC409.08 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CU329671 Genomic DNA Translation: CAB52610.2 Sequence problems. |
RefSeqi | NP_595458.1, NM_001021368.2 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
BioGRIDi | 277530, 7 interactors |
STRINGi | 4896.SPBC409.08.1 |
Protein family/group databases
TCDBi | 2.A.1.2.108, the major facilitator superfamily (mfs) |
Proteomic databases
PaxDbi | Q7Z9I0 |
Genome annotation databases
EnsemblFungii | SPBC409.08.1; SPBC409.08.1:pep; SPBC409.08 |
GeneIDi | 2541015 |
KEGGi | spo:SPBC409.08 |
Organism-specific databases
PomBasei | SPBC409.08 |
Phylogenomic databases
eggNOGi | KOG0255, Eukaryota |
HOGENOMi | CLU_008455_11_5_1 |
InParanoidi | Q7Z9I0 |
Miscellaneous databases
PROi | PR:Q7Z9I0 |
Family and domain databases
Gene3Di | 1.20.1250.20, 1 hit |
InterProi | View protein in InterPro IPR011701, MFS IPR020846, MFS_dom IPR036259, MFS_trans_sf IPR005829, Sugar_transporter_CS |
Pfami | View protein in Pfam PF07690, MFS_1, 1 hit |
SUPFAMi | SSF103473, SSF103473, 1 hit |
PROSITEi | View protein in PROSITE PS50850, MFS, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | YHA8_SCHPO | |
Accessioni | Q7Z9I0Primary (citable) accession number: Q7Z9I0 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | May 5, 2009 |
Last sequence update: | October 5, 2016 | |
Last modified: | September 29, 2021 | |
This is version 110 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Fungal Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Schizosaccharomyces pombe
Schizosaccharomyces pombe: entries and gene names - SIMILARITY comments
Index of protein domains and families