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Entry version 133 (18 Sep 2019)
Sequence version 1 (01 Oct 2003)
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Protein

Centromere protein V

Gene

CENPV

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Required for distribution of pericentromeric heterochromatin in interphase nuclei and for centromere formation and organization, chromosome alignment and cytokinesis.1 Publication

<p>This subsection of the ‘Function’ section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

Zn2+PROSITE-ProRule annotationNote: Binds 2 Zn2+ ions per subunit.PROSITE-ProRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the ‘Description’ field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi152Zinc 1; structuralPROSITE-ProRule annotation1
Metal bindingi154Zinc 1; structuralPROSITE-ProRule annotation1
Metal bindingi172Zinc 2; catalyticPROSITE-ProRule annotation1
Metal bindingi174Zinc 2; catalyticPROSITE-ProRule annotation1
Metal bindingi177Zinc 2; catalyticPROSITE-ProRule annotation1
Metal bindingi216Zinc 1; structuralPROSITE-ProRule annotation1
Metal bindingi219Zinc 1; structuralPROSITE-ProRule annotation1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processCell cycle, Cell division, Mitosis
LigandMetal-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Centromere protein V
Short name:
CENP-V
Alternative name(s):
Nuclear protein p30
Proline-rich protein 6
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:CENPV
Synonyms:PRR6
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 17

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:29920 CENPV

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
608139 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q7Z7K6

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Centromere, Chromosome, Cytoplasm, Cytoskeleton, Kinetochore, Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology_and_biotech_section">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi172C → A: Abolishes chromatin hypercondensation phenotype induced by overexpression of wild-type protein; when associated with A-177. 1 Publication1
Mutagenesisi174C → A: Abolishes chromatin hypercondensation phenotype induced by overexpression of wild-type protein. 1 Publication1
Mutagenesisi177C → A: Abolishes chromatin hypercondensation phenotype induced by overexpression of wild-type protein; when associated with A-172. 1 Publication1

Organism-specific databases

DisGeNET

More...
DisGeNETi
201161

Open Targets

More...
OpenTargetsi
ENSG00000166582

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA164717842

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q7Z7K6

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
CENPV

Domain mapping of disease mutations (DMDM)

More...
DMDMi
74750244

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002443591 – 275Centromere protein VAdd BLAST275

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei18PhosphoserineCombined sources1
Modified residuei21PhosphoserineCombined sources1
Modified residuei43Omega-N-methylarginineBy similarity1
Modified residuei98PhosphothreonineCombined sources1
Modified residuei101PhosphothreonineCombined sources1
Modified residuei103PhosphothreonineCombined sources1
Modified residuei257PhosphoserineBy similarity1

Keywords - PTMi

Methylation, Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q7Z7K6

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q7Z7K6

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q7Z7K6

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q7Z7K6

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q7Z7K6

PeptideAtlas

More...
PeptideAtlasi
Q7Z7K6

PRoteomics IDEntifications database

More...
PRIDEi
Q7Z7K6

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
69557 [Q7Z7K6-1]
69558 [Q7Z7K6-2]
69559 [Q7Z7K6-3]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q7Z7K6

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q7Z7K6

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
Q7Z7K6

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000166582 Expressed in 176 organ(s), highest expression level in cerebral cortex

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q7Z7K6 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q7Z7K6 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA042529
HPA042616

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
128365, 34 interactors

Protein interaction database and analysis system

More...
IntActi
Q7Z7K6, 30 interactors

Molecular INTeraction database

More...
MINTi
Q7Z7K6

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000299736

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q7Z7K6

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini148 – 260CENP-V/GFAPROSITE-ProRule annotationAdd BLAST113

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi23 – 36Poly-AlaAdd BLAST14
Compositional biasi59 – 102Pro-richAdd BLAST44

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the Gfa family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG4192 Eukaryota
COG3791 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000003183

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000090254

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q7Z7K6

Identification of Orthologs from Complete Genome Data

More...
OMAi
NGSNWEK

Database of Orthologous Groups

More...
OrthoDBi
1326510at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q7Z7K6

TreeFam database of animal gene trees

More...
TreeFami
TF313636

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR006913 GFA/CENP-V
IPR011057 Mss4-like_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF04828 GFA, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF51316 SSF51316, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51891 CENP_V_GFA, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q7Z7K6-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MRRSRSSAAA KLRGQKRSGA SGASAAPAAS AAAALAPSAT RTRRSASQAG
60 70 80 90 100
SKSQAVEKPP SEKPRLRRSS PRAQEEGPGE PPPPELALLP PPPPPPPTPA
110 120 130 140 150
TPTSSASNLD LGEQRERWET FQKRQKLTSE GAAKLLLDTF EYQGLVKHTG
160 170 180 190 200
GCHCGAVRFE VWASADLHIF DCNCSICKKK QNRHFIVPAS RFKLLKGAEH
210 220 230 240 250
ITTYTFNTHK AQHTFCKRCG VQSFYTPRSN PGGFGIAPHC LDEGTVRSMV
260 270
TEEFNGSDWE KAMKEHKTIK NMSKE
Length:275
Mass (Da):29,946
Last modified:October 1, 2003 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iE9A69F1F9BA746D8
GO
Isoform 2 (identifier: Q7Z7K6-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-173: MRRSRSSAAA...SADLHIFDCN → MQVAAHNLEFALSFCS

Show »
Length:118
Mass (Da):13,415
Checksum:iD2AFAF27CE996704
GO
Isoform 3 (identifier: Q7Z7K6-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     18-20: Missing.

Show »
Length:272
Mass (Da):29,731
Checksum:i3E3A33B9CEBFDB3E
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0M3HER2A0A0M3HER2_HUMAN
Centromere protein V
CENPV
175Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
K7ERN6K7ERN6_HUMAN
Centromere protein V
CENPV
14Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0195491 – 173MRRSR…IFDCN → MQVAAHNLEFALSFCS in isoform 2. 1 PublicationAdd BLAST173
Alternative sequenceiVSP_01955018 – 20Missing in isoform 3. 2 Publications3

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AY382899 mRNA Translation: AAR24368.1
BC052604 mRNA Translation: AAH52604.1
BC137486 mRNA Translation: AAI37487.1
BC137487 mRNA Translation: AAI37488.1
AF514992 mRNA Translation: AAM76703.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS32575.1 [Q7Z7K6-3]

NCBI Reference Sequences

More...
RefSeqi
NP_859067.2, NM_181716.2 [Q7Z7K6-3]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000299736; ENSP00000299736; ENSG00000166582 [Q7Z7K6-3]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
201161

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:201161

UCSC genome browser

More...
UCSCi
uc002gpw.4 human [Q7Z7K6-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY382899 mRNA Translation: AAR24368.1
BC052604 mRNA Translation: AAH52604.1
BC137486 mRNA Translation: AAI37487.1
BC137487 mRNA Translation: AAI37488.1
AF514992 mRNA Translation: AAM76703.1
CCDSiCCDS32575.1 [Q7Z7K6-3]
RefSeqiNP_859067.2, NM_181716.2 [Q7Z7K6-3]

3D structure databases

SMRiQ7Z7K6
ModBaseiSearch...

Protein-protein interaction databases

BioGridi128365, 34 interactors
IntActiQ7Z7K6, 30 interactors
MINTiQ7Z7K6
STRINGi9606.ENSP00000299736

PTM databases

iPTMnetiQ7Z7K6
PhosphoSitePlusiQ7Z7K6
SwissPalmiQ7Z7K6

Polymorphism and mutation databases

BioMutaiCENPV
DMDMi74750244

Proteomic databases

EPDiQ7Z7K6
jPOSTiQ7Z7K6
MassIVEiQ7Z7K6
MaxQBiQ7Z7K6
PaxDbiQ7Z7K6
PeptideAtlasiQ7Z7K6
PRIDEiQ7Z7K6
ProteomicsDBi69557 [Q7Z7K6-1]
69558 [Q7Z7K6-2]
69559 [Q7Z7K6-3]

Genome annotation databases

EnsembliENST00000299736; ENSP00000299736; ENSG00000166582 [Q7Z7K6-3]
GeneIDi201161
KEGGihsa:201161
UCSCiuc002gpw.4 human [Q7Z7K6-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
201161
DisGeNETi201161

GeneCards: human genes, protein and diseases

More...
GeneCardsi
CENPV
HGNCiHGNC:29920 CENPV
HPAiHPA042529
HPA042616
MIMi608139 gene
neXtProtiNX_Q7Z7K6
OpenTargetsiENSG00000166582
PharmGKBiPA164717842

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG4192 Eukaryota
COG3791 LUCA
GeneTreeiENSGT00390000003183
HOGENOMiHOG000090254
InParanoidiQ7Z7K6
OMAiNGSNWEK
OrthoDBi1326510at2759
PhylomeDBiQ7Z7K6
TreeFamiTF313636

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
CENPV human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
201161
PharosiQ7Z7K6

Protein Ontology

More...
PROi
PR:Q7Z7K6

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000166582 Expressed in 176 organ(s), highest expression level in cerebral cortex
ExpressionAtlasiQ7Z7K6 baseline and differential
GenevisibleiQ7Z7K6 HS

Family and domain databases

InterProiView protein in InterPro
IPR006913 GFA/CENP-V
IPR011057 Mss4-like_sf
PfamiView protein in Pfam
PF04828 GFA, 1 hit
SUPFAMiSSF51316 SSF51316, 1 hit
PROSITEiView protein in PROSITE
PS51891 CENP_V_GFA, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCENPV_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q7Z7K6
Secondary accession number(s): B2RPK2, Q3L8N5, Q8NFH6
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: October 1, 2003
Last modified: September 18, 2019
This is version 133 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. Human chromosome 17
    Human chromosome 17: entries, gene names and cross-references to MIM
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