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UniProtKB - Q7Z7K2 (ZN467_HUMAN)

Entry version 139 (16 Oct 2019)
Sequence version 1 (01 Oct 2003)
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Protein

Zinc finger protein 467

Gene

ZNF467

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Transcription factor that promotes adipocyte differentiation and suppresses osteoblast differentiation in the bone marrow. Enhances the osteoclast-supporting ability of stromal cells. Binds with STAT3 the consensus sequence 5'-CTTCTGGGAAGA-3' of the acute phase response element (APRE). Transactivates several promoters including FOS, OSM and PPARG. Recruits a histone deacetylase complex (By similarity).By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri160 – 182C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri188 – 210C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri216 – 238C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri244 – 266C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri272 – 294C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri300 – 322C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri355 – 377C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri431 – 453C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri459 – 481C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri487 – 509C2H2-type 10PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri515 – 537C2H2-type 11PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri543 – 565C2H2-type 12PROSITE-ProRule annotationAdd BLAST23

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...Reactomei		R-HSA-381340 Transcriptional regulation of white adipocyte differentiation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Zinc finger protein 467
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ZNF467
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 7

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:23154 ZNF467

Online Mendelian Inheritance in Man (OMIM)

More...MIMi		614040 gene

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q7Z7K2

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...OpenTargetsi		ENSG00000181444

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA134886769

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q7Z7K2

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		ZNF467

Domain mapping of disease mutations (DMDM)

More...DMDMi		74762444

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002475171 – 595Zinc finger protein 467Add BLAST595

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section describes <strong>covalent linkages</strong> of various types formed <strong>between two proteins (interchain cross-links)</strong> or <strong>between two parts of the same protein (intrachain cross-links)</strong>, except the disulfide bonds that are annotated in the <a href="http://www.uniprot.org/manual/disulfid">'Disulfide bond'</a> subsection.<p><a href='/help/crosslnk' target='_top'>More...</a></p>Cross-linki97Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Cross-linki368Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources

Keywords - PTMi

Isopeptide bond, Ubl conjugation

Proteomic databases

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q7Z7K2

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q7Z7K2

PeptideAtlas

More...PeptideAtlasi		Q7Z7K2

PRoteomics IDEntifications database

More...PRIDEi		Q7Z7K2

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		69556

Consortium for Top Down Proteomics

More...TopDownProteomicsi		Q7Z7K2

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q7Z7K2

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q7Z7K2

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000181444 Expressed in 147 organ(s), highest expression level in blood

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q7Z7K2 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q7Z7K2 HS

Organism-specific databases

Human Protein Atlas

More...HPAi		HPA042907

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with STAT3. Enhances STAT3 activity by keeping it in the nucleus (By similarity).

By similarity

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...BioGridi		127969, 5 interactors

Protein interaction database and analysis system

More...IntActi		Q7Z7K2, 4 interactors

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000304769

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q7Z7K2

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the krueppel C2H2-type zinc-finger protein family.Curated

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri160 – 182C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri188 – 210C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri216 – 238C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri244 – 266C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri272 – 294C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri300 – 322C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri355 – 377C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri431 – 453C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri459 – 481C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri487 – 509C2H2-type 10PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri515 – 537C2H2-type 11PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri543 – 565C2H2-type 12PROSITE-ProRule annotationAdd BLAST23

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG1721 Eukaryota
COG5048 LUCA

Ensembl GeneTree

More...GeneTreei		ENSGT00940000162497

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		HOG000234617

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q7Z7K2

Identification of Orthologs from Complete Genome Data

More...OMAi		CSGDEWM

Database of Orthologous Groups

More...OrthoDBi		1318335at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q7Z7K2

TreeFam database of animal gene trees

More...TreeFami		TF326846

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00096 zf-C2H2, 8 hits

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00355 ZnF_C2H2, 12 hits

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF57667 SSF57667, 7 hits

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS00028 ZINC_FINGER_C2H2_1, 12 hits
PS50157 ZINC_FINGER_C2H2_2, 12 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q7Z7K2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRETLEALSS LGFSVGQPEM APQSEPREGS HNAQEQMSSS REERALGVCS 
        60         70         80         90        100
GHEAPTPEEG AHTEQAEAPC RGQACSAQKA QPVGTCPGEE WMIRKVKVED 
       110        120        130        140        150
EDQEAEEEVE WPQHLSLLPS PFPAPDLGHL AAAYKLEPGA PGALSGLALS 
       160        170        180        190        200
GWGPMPEKPY GCGECERRFR DQLTLRLHQR LHRGEGPCAC PDCGRSFTQR 
       210        220        230        240        250
AHMLLHQRSH RGERPFPCSE CDKRFSKKAH LTRHLRTHTG ERPYPCAECG 
       260        270        280        290        300
KRFSQKIHLG SHQKTHTGER PFPCTECEKR FRKKTHLIRH QRIHTGERPY 
       310        320        330        340        350
QCAQCARSFT HKQHLVRHQR VHQTAGPARP SPDSSASPHS TAPSPTPSFP 
       360        370        380        390        400
GPKPFACSDC GLSFGWKKNL ATHQCLHRSE GRPFGCDECA LGATVDAPAA 
       410        420        430        440        450
KPLASAPGGP GCGPGSDPVV PQRAPSGERS FFCPDCGRGF SHGQHLARHP 
       460        470        480        490        500
RVHTGERPFA CTQCDRRFGS RPNLVAHSRA HSGARPFACA QCGRRFSRKS 
       510        520        530        540        550
HLGRHQAVHT GSRPHACAVC ARSFSSKTNL VRHQAIHTGS RPFSCPQCGK 
       560        570        580        590 
SFSRKTHLVR HQLIHGEAAH AAPDAALAAP AWSAPPEVAP PPLFF
Length:595
Mass (Da):65,124
Last modified:October 1, 2003 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i8D0C6EEE42310BF6
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
C9JAX3C9JAX3_HUMAN
Zinc finger protein 467
ZNF467
146Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_052835324T → A. Corresponds to variant dbSNP:rs6965332Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
BC052625 mRNA Translation: AAH52625.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS5899.1

NCBI Reference Sequences

More...RefSeqi		NP_997219.1, NM_207336.2
XP_005250016.1, XM_005249959.4
XP_005250017.1, XM_005249960.4
XP_005250018.1, XM_005249961.4
XP_011514160.1, XM_011515858.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000302017; ENSP00000304769; ENSG00000181444

Database of genes from NCBI RefSeq genomes

More...GeneIDi		168544

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:168544

UCSC genome browser

More...UCSCi		uc003wgd.3 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC052625 mRNA Translation: AAH52625.1
CCDSiCCDS5899.1
RefSeqiNP_997219.1, NM_207336.2
XP_005250016.1, XM_005249959.4
XP_005250017.1, XM_005249960.4
XP_005250018.1, XM_005249961.4
XP_011514160.1, XM_011515858.1

3D structure databases

SMRiQ7Z7K2
ModBaseiSearch...

Protein-protein interaction databases

BioGridi127969, 5 interactors
IntActiQ7Z7K2, 4 interactors
STRINGi9606.ENSP00000304769

PTM databases

iPTMnetiQ7Z7K2
PhosphoSitePlusiQ7Z7K2

Polymorphism and mutation databases

BioMutaiZNF467
DMDMi74762444

Proteomic databases

MassIVEiQ7Z7K2
PaxDbiQ7Z7K2
PeptideAtlasiQ7Z7K2
PRIDEiQ7Z7K2
ProteomicsDBi69556
TopDownProteomicsiQ7Z7K2

Genome annotation databases

EnsembliENST00000302017; ENSP00000304769; ENSG00000181444
GeneIDi168544
KEGGihsa:168544
UCSCiuc003wgd.3 human

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		168544

GeneCards: human genes, protein and diseases

More...GeneCardsi		ZNF467
HGNCiHGNC:23154 ZNF467
HPAiHPA042907
MIMi614040 gene
neXtProtiNX_Q7Z7K2
OpenTargetsiENSG00000181444
PharmGKBiPA134886769

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG1721 Eukaryota
COG5048 LUCA
GeneTreeiENSGT00940000162497
HOGENOMiHOG000234617
InParanoidiQ7Z7K2
OMAiCSGDEWM
OrthoDBi1318335at2759
PhylomeDBiQ7Z7K2
TreeFamiTF326846

Enzyme and pathway databases

ReactomeiR-HSA-381340 Transcriptional regulation of white adipocyte differentiation

Miscellaneous databases

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		168544
PharosiQ7Z7K2

Protein Ontology

More...PROi		PR:Q7Z7K2

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSG00000181444 Expressed in 147 organ(s), highest expression level in blood
ExpressionAtlasiQ7Z7K2 baseline and differential
GenevisibleiQ7Z7K2 HS

Family and domain databases

InterProiView protein in InterPro
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
PfamiView protein in Pfam
PF00096 zf-C2H2, 8 hits
SMARTiView protein in SMART
SM00355 ZnF_C2H2, 12 hits
SUPFAMiSSF57667 SSF57667, 7 hits
PROSITEiView protein in PROSITE
PS00028 ZINC_FINGER_C2H2_1, 12 hits
PS50157 ZINC_FINGER_C2H2_2, 12 hits

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiZN467_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q7Z7K2
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 25, 2006
Last sequence update: October 1, 2003
Last modified: October 16, 2019
This is version 139 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 7
    Human chromosome 7: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
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