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Entry version 122 (07 Apr 2021)
Sequence version 2 (23 Oct 2007)
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Protein

Allergin-1

Gene

MILR1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Immunoglobulin-like receptor which plays an inhibitory role in degranulation of mast cells. Negatively regulates IgE-mediated mast cell activation and suppresses the type I immediate hypersensitivity reaction (By similarity).By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
Q7Z6M3

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Allergin-1
Alternative name(s):
Allergy inhibitory receptor 1
Mast cell antigen 32
Short name:
MCA-32
Mast cell immunoglobulin-like receptor 1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:MILR1
Synonyms:C17orf60, MCA32
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 17

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:27570, MILR1

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q7Z6M3

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
HostDB:ENSG00000271605.5

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini20 – 227ExtracellularSequence analysisAdd BLAST208
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei228 – 248HelicalSequence analysisAdd BLAST21
Topological domaini249 – 343CytoplasmicSequence analysisAdd BLAST95

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cell membrane, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
284021

Open Targets

More...
OpenTargetsi
ENSG00000271605

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA142672243

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q7Z6M3, Tdark

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
MILR1

Domain mapping of disease mutations (DMDM)

More...
DMDMi
160013631

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 19Sequence analysisAdd BLAST19
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000030736420 – 343Allergin-1Add BLAST324

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi51N-linked (GlcNAc...) asparagineSequence analysis1
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi56 ↔ 103By similarity
Glycosylationi60N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi89N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi147 ↔ 196By similarity
Glycosylationi151N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi157N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi182N-linked (GlcNAc...) asparagineSequence analysis1
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei313PhosphotyrosineBy similarity1
Modified residuei338PhosphotyrosineBy similarity1

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

N-glycosylated.1 Publication

Keywords - PTMi

Disulfide bond, Glycoprotein, Phosphoprotein

Proteomic databases

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q7Z6M3

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q7Z6M3

PeptideAtlas

More...
PeptideAtlasi
Q7Z6M3

PRoteomics IDEntifications database

More...
PRIDEi
Q7Z6M3

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
69447 [Q7Z6M3-1]
69448 [Q7Z6M3-2]
69449 [Q7Z6M3-3]

PTM databases

GlyGen: Computational and Informatics Resources for Glycoscience

More...
GlyGeni
Q7Z6M3, 6 sites

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q7Z6M3

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q7Z6M3

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed in myeloid cells (dendritic cells, macrophages and neutrophils, weak expression on B-cells but not in T-cells or natural killer cells), peripheral blood basophils and mast cells (at protein level).1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000271605, Expressed in monocyte and 165 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q7Z6M3, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q7Z6M3, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000271605, Tissue enhanced (blood)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Monomer.

Interacts (tyrosine-phosphorylated) with PTPN6, PTPN11 and INPP5D.

By similarity

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

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BioGRIDi
129734, 14 interactors

Protein interaction database and analysis system

More...
IntActi
Q7Z6M3, 13 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000482801

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q7Z6M3, protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini35 – 118Ig-like C2-type 1Add BLAST84
Domaini128 – 213Ig-like C2-type 2Add BLAST86

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi311 – 316ITIM motif6
Motifi336 – 341ITIM motif6

Keywords - Domaini

Immunoglobulin domain, Repeat, Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502S5BW, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT01020000230339

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_069833_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q7Z6M3

Identification of Orthologs from Complete Genome Data

More...
OMAi
CENQAGK

Database of Orthologous Groups

More...
OrthoDBi
1405395at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q7Z6M3

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.40.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR029626, Allergin-1
IPR036179, Ig-like_dom_sf
IPR013783, Ig-like_fold
IPR040878, Ig_C17orf99

The PANTHER Classification System

More...
PANTHERi
PTHR11481:SF58, PTHR11481:SF58, 1 hit

Pfam protein domain database

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Pfami
View protein in Pfam
PF17736, Ig_C17orf99, 2 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48726, SSF48726, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 3 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q7Z6M3-1) [UniParc]FASTAAdd to basket
Also known as: L

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MWSHLNRLLF WSIFSSVTCR KAVLDCEAMK TNEFPSPCLD SKTKVVMKGQ
60 70 80 90 100
NVSMFCSHKN KSLQITYSLF RRKTHLGTQD GKGEPAIFNL SITEAHESGP
110 120 130 140 150
YKCKAQVTSC SKYSRDFSFT IVDPVTSPVL NIMVIQTETD RHITLHCLSV
160 170 180 190 200
NGSLPINYTF FENHVAISPA ISKYDREPAE FNLTKKNPGE EEEYRCEAKN
210 220 230 240 250
RLPNYATYSH PVTMPSTGGD SCPFCLKLLL PGLLLLLVVI ILILAFWVLP
260 270 280 290 300
KYKTRKAMRN NVPRDRGDTA MEVGIYANIL EKQAKEESVP EVGSRPCVST
310 320 330 340
AQDEAKHSQE LQYATPVFQE VAPREQEACD SYKSGYVYSE LNF
Length:343
Mass (Da):38,735
Last modified:October 23, 2007 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iDCD1E784D40885C5
GO
Isoform 2 (identifier: Q7Z6M3-2) [UniParc]FASTAAdd to basket
Also known as: S1

The sequence of this isoform differs from the canonical sequence as follows:
     123-217: Missing.

Show »
Length:248
Mass (Da):27,959
Checksum:iCEAF690185D35DF9
GO
Isoform 3 (identifier: Q7Z6M3-3) [UniParc]FASTAAdd to basket
Also known as: S2

The sequence of this isoform differs from the canonical sequence as follows:
     33-122: Missing.

Show »
Length:253
Mass (Da):28,656
Checksum:iF126B2CEFDCE53B7
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A087WVL4A0A087WVL4_HUMAN
Allergin-1
MILR1
186Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
S4R3N6S4R3N6_HUMAN
Allergin-1
MILR1
89Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAI36595 differs from that shown. Reason: Erroneous initiation. Truncated N-terminus.Curated
The sequence BAG62433 differs from that shown. Reason: Erroneous initiation. Extended N-terminus.Curated

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_04076533 – 122Missing in isoform 3. 1 PublicationAdd BLAST90
Alternative sequenceiVSP_040766123 – 217Missing in isoform 2. 2 PublicationsAdd BLAST95

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AB542950 mRNA Translation: BAJ08251.1
AB542951 mRNA Translation: BAJ08252.1
AB542952 mRNA Translation: BAJ08253.1
AK300768 mRNA Translation: BAG62433.1 Different initiation.
BC053534 mRNA Translation: AAH53534.1
BC130406 mRNA Translation: AAI30407.2
BC136594 mRNA Translation: AAI36595.1 Different initiation.
BC144272 mRNA Translation: AAI44273.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS74133.1 [Q7Z6M3-1]
CCDS77087.1 [Q7Z6M3-2]
CCDS77088.1 [Q7Z6M3-3]

NCBI Reference Sequences

More...
RefSeqi
NP_001078892.1, NM_001085423.1 [Q7Z6M3-1]
NP_001278245.1, NM_001291316.1 [Q7Z6M3-2]
NP_001278246.1, NM_001291317.1 [Q7Z6M3-3]
XP_016879975.1, XM_017024486.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000612535; ENSP00000477504; ENSG00000271605 [Q7Z6M3-3]
ENST00000615220; ENSP00000480749; ENSG00000271605 [Q7Z6M3-1]
ENST00000616498; ENSP00000481318; ENSG00000271605 [Q7Z6M3-2]
ENST00000619286; ENSP00000482801; ENSG00000271605 [Q7Z6M3-1]

Database of genes from NCBI RefSeq genomes

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GeneIDi
284021

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:284021

UCSC genome browser

More...
UCSCi
uc010wpz.4, human [Q7Z6M3-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB542950 mRNA Translation: BAJ08251.1
AB542951 mRNA Translation: BAJ08252.1
AB542952 mRNA Translation: BAJ08253.1
AK300768 mRNA Translation: BAG62433.1 Different initiation.
BC053534 mRNA Translation: AAH53534.1
BC130406 mRNA Translation: AAI30407.2
BC136594 mRNA Translation: AAI36595.1 Different initiation.
BC144272 mRNA Translation: AAI44273.1
CCDSiCCDS74133.1 [Q7Z6M3-1]
CCDS77087.1 [Q7Z6M3-2]
CCDS77088.1 [Q7Z6M3-3]
RefSeqiNP_001078892.1, NM_001085423.1 [Q7Z6M3-1]
NP_001278245.1, NM_001291316.1 [Q7Z6M3-2]
NP_001278246.1, NM_001291317.1 [Q7Z6M3-3]
XP_016879975.1, XM_017024486.1

3D structure databases

Database of comparative protein structure models

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ModBasei
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SWISS-MODEL Interactive Workspace

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SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi129734, 14 interactors
IntActiQ7Z6M3, 13 interactors
STRINGi9606.ENSP00000482801

PTM databases

GlyGeniQ7Z6M3, 6 sites
iPTMnetiQ7Z6M3
PhosphoSitePlusiQ7Z6M3

Genetic variation databases

BioMutaiMILR1
DMDMi160013631

Proteomic databases

MassIVEiQ7Z6M3
MaxQBiQ7Z6M3
PeptideAtlasiQ7Z6M3
PRIDEiQ7Z6M3
ProteomicsDBi69447 [Q7Z6M3-1]
69448 [Q7Z6M3-2]
69449 [Q7Z6M3-3]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

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Antibodypediai
68852, 106 antibodies

Genome annotation databases

EnsembliENST00000612535; ENSP00000477504; ENSG00000271605 [Q7Z6M3-3]
ENST00000615220; ENSP00000480749; ENSG00000271605 [Q7Z6M3-1]
ENST00000616498; ENSP00000481318; ENSG00000271605 [Q7Z6M3-2]
ENST00000619286; ENSP00000482801; ENSG00000271605 [Q7Z6M3-1]
GeneIDi284021
KEGGihsa:284021
UCSCiuc010wpz.4, human [Q7Z6M3-1]

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
284021
DisGeNETi284021

GeneCards: human genes, protein and diseases

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GeneCardsi
MILR1
HGNCiHGNC:27570, MILR1
HPAiENSG00000271605, Tissue enhanced (blood)
neXtProtiNX_Q7Z6M3
OpenTargetsiENSG00000271605
PharmGKBiPA142672243
VEuPathDBiHostDB:ENSG00000271605.5

GenAtlas: human gene database

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GenAtlasi
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Phylogenomic databases

eggNOGiENOG502S5BW, Eukaryota
GeneTreeiENSGT01020000230339
HOGENOMiCLU_069833_0_0_1
InParanoidiQ7Z6M3
OMAiCENQAGK
OrthoDBi1405395at2759
PhylomeDBiQ7Z6M3

Enzyme and pathway databases

PathwayCommonsiQ7Z6M3

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

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BioGRID-ORCSi
284021, 4 hits in 161 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
MILR1, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
284021
PharosiQ7Z6M3, Tdark

Protein Ontology

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PROi
PR:Q7Z6M3
RNActiQ7Z6M3, protein

Gene expression databases

BgeeiENSG00000271605, Expressed in monocyte and 165 other tissues
ExpressionAtlasiQ7Z6M3, baseline and differential
GenevisibleiQ7Z6M3, HS

Family and domain databases

Gene3Di2.60.40.10, 1 hit
InterProiView protein in InterPro
IPR029626, Allergin-1
IPR036179, Ig-like_dom_sf
IPR013783, Ig-like_fold
IPR040878, Ig_C17orf99
PANTHERiPTHR11481:SF58, PTHR11481:SF58, 1 hit
PfamiView protein in Pfam
PF17736, Ig_C17orf99, 2 hits
SUPFAMiSSF48726, SSF48726, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiMILR1_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q7Z6M3
Secondary accession number(s): A1L458
, B4DUS1, B7ZM50, B9EGN0, D6RUW6, D6RUW8
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 23, 2007
Last sequence update: October 23, 2007
Last modified: April 7, 2021
This is version 122 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 17
    Human chromosome 17: entries, gene names and cross-references to MIM
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