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Protein

General receptor for phosphoinositides 1-associated scaffold protein

Gene

GRASP

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Plays a role in intracellular trafficking and contributes to the macromolecular organization of group 1 metabotropic glutamate receptors (mGluRs) at synapses.By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

SignaLink: a signaling pathway resource with multi-layered regulatory networks

More...
SignaLinki
Q7Z6J2

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
General receptor for phosphoinositides 1-associated scaffold protein
Short name:
GRP1-associated scaffold protein
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:GRASP
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 12

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000161835.10

Human Gene Nomenclature Database

More...
HGNCi
HGNC:18707 GRASP

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
612027 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q7Z6J2

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cell junction, Cell membrane, Cytoplasm, Membrane, Postsynaptic cell membrane, Synapse

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
160622

Open Targets

More...
OpenTargetsi
ENSG00000161835

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA38651

Polymorphism and mutation databases

Domain mapping of disease mutations (DMDM)

More...
DMDMi
74738818

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000875841 – 395General receptor for phosphoinositides 1-associated scaffold proteinAdd BLAST395

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei77PhosphothreonineBy similarity1
Modified residuei94PhosphoserineBy similarity1
Modified residuei237PhosphotyrosineCombined sources1
Modified residuei270Omega-N-methylarginineBy similarity1
Modified residuei387PhosphoserineBy similarity1

Keywords - PTMi

Methylation, Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q7Z6J2

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q7Z6J2

PeptideAtlas

More...
PeptideAtlasi
Q7Z6J2

PRoteomics IDEntifications database

More...
PRIDEi
Q7Z6J2

ProteomicsDB human proteome resource

More...
ProteomicsDBi
69419
69420 [Q7Z6J2-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q7Z6J2

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q7Z6J2

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000161835 Expressed in 193 organ(s), highest expression level in right lung

CleanEx database of gene expression profiles

More...
CleanExi
HS_GRASP

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q7Z6J2 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q7Z6J2 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA040664
HPA062028

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Heteromer. Composed of GRASP, PSCD2 and at least one GRM1. Also interacts with PSCD3, GRM2, GRM3 and GRM5 (By similarity).By similarity

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
127762, 6 interactors

CORUM comprehensive resource of mammalian protein complexes

More...
CORUMi
Q7Z6J2

Protein interaction database and analysis system

More...
IntActi
Q7Z6J2, 1 interactor

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000293662

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1395
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
Q7Z6J2

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q7Z6J2

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...
EvolutionaryTracei
Q7Z6J2

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini101 – 190PDZPROSITE-ProRule annotationAdd BLAST90

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni181 – 258Interaction with PSCD3By similarityAdd BLAST78

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi295 – 324Pro-richAdd BLAST30

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3528 Eukaryota
ENOG410ZJVP LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00530000063734

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000231871

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG053061

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q7Z6J2

Identification of Orthologs from Complete Genome Data

More...
OMAi
TLHEKWD

Database of Orthologous Groups

More...
OrthoDBi
EOG091G0NRM

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q7Z6J2

TreeFam database of animal gene trees

More...
TreeFami
TF316315

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001478 PDZ
IPR036034 PDZ_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00595 PDZ, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00228 PDZ, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF50156 SSF50156, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50106 PDZ, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform 1 (identifier: Q7Z6J2-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MTLRRLRKLQ QKEEAAATPD PAARTPDSEV APAAPVPTPG PPAAAATPGP
60 70 80 90 100
PADELYAALE DYHPAELYRA LAVSGGTLPR RKGSGFRWKN LSQSPEQQRK
110 120 130 140 150
VLTLEKEDNQ TFGFEIQTYG LHHREEQRVE MVTFVCRVHE SSPAQLAGLT
160 170 180 190 200
PGDTIASVNG LNVEGIRHRE IVDIIKASGN VLRLETLYGT SIRKAELEAR
210 220 230 240 250
LQYLKQTLYE KWGEYRSLMV QEQRLVHGLV VKDPSIYDTL ESVRSCLYGA
260 270 280 290 300
GLLPGSLPFG PLLAVPGRPR GGARRARGDA DDAVYHTCFF GDSEPPALPP
310 320 330 340 350
PPPPARAFGP GPAETPAVGP GPGPRAALSR SASVRCAGPG GGGGGGAPGA
360 370 380 390
LWTEAREQAL CGPGLRKTKY RSFRRRLLKF IPGLNRSLEE EESQL
Length:395
Mass (Da):42,623
Last modified:October 1, 2003 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iB042CA2298753CB9
GO
Isoform 2 (identifier: Q7Z6J2-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-143: Missing.
     144-151: AQLAGLTP → MTLLPSKG

Note: No experimental confirmation available.
Show »
Length:252
Mass (Da):26,904
Checksum:i8A71C34EA285BE1E
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F8VRX5F8VRX5_HUMAN
General receptor for phosphoinositi...
GRASP
221Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting. The information stored in this subsection is used to automatically construct alternative protein sequence(s) for display.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0157071 – 143Missing in isoform 2. 1 PublicationAdd BLAST143
Alternative sequenceiVSP_015708144 – 151AQLAGLTP → MTLLPSKG in isoform 2. 1 Publication8

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
BC035500 mRNA Translation: AAH35500.1
BC052967 mRNA Translation: AAH52967.1
BC053666 mRNA Translation: AAH53666.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS61124.1 [Q7Z6J2-2]
CCDS8817.1 [Q7Z6J2-1]

NCBI Reference Sequences

More...
RefSeqi
NP_001258785.1, NM_001271856.1 [Q7Z6J2-2]
NP_859062.1, NM_181711.3 [Q7Z6J2-1]

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.407202

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000293662; ENSP00000293662; ENSG00000161835 [Q7Z6J2-1]
ENST00000552049; ENSP00000449492; ENSG00000161835 [Q7Z6J2-2]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
160622

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:160622

UCSC genome browser

More...
UCSCi
uc001rzo.3 human [Q7Z6J2-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC035500 mRNA Translation: AAH35500.1
BC052967 mRNA Translation: AAH52967.1
BC053666 mRNA Translation: AAH53666.1
CCDSiCCDS61124.1 [Q7Z6J2-2]
CCDS8817.1 [Q7Z6J2-1]
RefSeqiNP_001258785.1, NM_001271856.1 [Q7Z6J2-2]
NP_859062.1, NM_181711.3 [Q7Z6J2-1]
UniGeneiHs.407202

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2PNTX-ray2.15A/B97-188[»]
ProteinModelPortaliQ7Z6J2
SMRiQ7Z6J2
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi127762, 6 interactors
CORUMiQ7Z6J2
IntActiQ7Z6J2, 1 interactor
STRINGi9606.ENSP00000293662

PTM databases

iPTMnetiQ7Z6J2
PhosphoSitePlusiQ7Z6J2

Polymorphism and mutation databases

DMDMi74738818

Proteomic databases

EPDiQ7Z6J2
PaxDbiQ7Z6J2
PeptideAtlasiQ7Z6J2
PRIDEiQ7Z6J2
ProteomicsDBi69419
69420 [Q7Z6J2-2]

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000293662; ENSP00000293662; ENSG00000161835 [Q7Z6J2-1]
ENST00000552049; ENSP00000449492; ENSG00000161835 [Q7Z6J2-2]
GeneIDi160622
KEGGihsa:160622
UCSCiuc001rzo.3 human [Q7Z6J2-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
160622
DisGeNETi160622
EuPathDBiHostDB:ENSG00000161835.10

GeneCards: human genes, protein and diseases

More...
GeneCardsi
GRASP

H-Invitational Database, human transcriptome db

More...
H-InvDBi
HIX0026388
HIX0037038
HGNCiHGNC:18707 GRASP
HPAiHPA040664
HPA062028
MIMi612027 gene
neXtProtiNX_Q7Z6J2
OpenTargetsiENSG00000161835
PharmGKBiPA38651

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG3528 Eukaryota
ENOG410ZJVP LUCA
GeneTreeiENSGT00530000063734
HOGENOMiHOG000231871
HOVERGENiHBG053061
InParanoidiQ7Z6J2
OMAiTLHEKWD
OrthoDBiEOG091G0NRM
PhylomeDBiQ7Z6J2
TreeFamiTF316315

Enzyme and pathway databases

SignaLinkiQ7Z6J2

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
GRASP human
EvolutionaryTraceiQ7Z6J2

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
160622

Protein Ontology

More...
PROi
PR:Q7Z6J2

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000161835 Expressed in 193 organ(s), highest expression level in right lung
CleanExiHS_GRASP
ExpressionAtlasiQ7Z6J2 baseline and differential
GenevisibleiQ7Z6J2 HS

Family and domain databases

InterProiView protein in InterPro
IPR001478 PDZ
IPR036034 PDZ_sf
PfamiView protein in Pfam
PF00595 PDZ, 1 hit
SMARTiView protein in SMART
SM00228 PDZ, 1 hit
SUPFAMiSSF50156 SSF50156, 1 hit
PROSITEiView protein in PROSITE
PS50106 PDZ, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiGRASP_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q7Z6J2
Secondary accession number(s): Q6PIF8, Q7Z741
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 27, 2005
Last sequence update: October 1, 2003
Last modified: November 7, 2018
This is version 126 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. Human chromosome 12
    Human chromosome 12: entries, gene names and cross-references to MIM
  3. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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