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Entry version 135 (29 Sep 2021)
Sequence version 1 (01 Oct 2003)
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Protein

BTB/POZ domain-containing protein KCTD20

Gene

KCTD20

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Promotes the phosphorylation of AKT family members.

By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
Q7Z5Y7

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
BTB/POZ domain-containing protein KCTD20
Alternative name(s):
Potassium channel tetramerization domain containing 20
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:KCTD20
Synonyms:C6orf69
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 6

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:21052, KCTD20

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
615932, gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q7Z5Y7

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
HostDB:ENSG00000112078

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cytoplasm

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
222658

Open Targets

More...
OpenTargetsi
ENSG00000112078

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134913479

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q7Z5Y7, Tdark

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
KCTD20

Domain mapping of disease mutations (DMDM)

More...
DMDMi
74750149

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002552481 – 419BTB/POZ domain-containing protein KCTD20Add BLAST419

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q7Z5Y7

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q7Z5Y7

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q7Z5Y7

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q7Z5Y7

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q7Z5Y7

PeptideAtlas

More...
PeptideAtlasi
Q7Z5Y7

PRoteomics IDEntifications database

More...
PRIDEi
Q7Z5Y7

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
26368
69360 [Q7Z5Y7-1]
69361 [Q7Z5Y7-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q7Z5Y7

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q7Z5Y7

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000112078, Expressed in amniotic fluid and 226 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q7Z5Y7, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q7Z5Y7, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000112078, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with AKT1; AKT2 and AKT3 (By similarity). Associates with PP2CA (By similarity).

Part of a complex containing MARK4 (PubMed:14676191).

By similarity1 Publication

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
128809, 10 interactors

Protein interaction database and analysis system

More...
IntActi
Q7Z5Y7, 8 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000362836

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q7Z5Y7, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q7Z5Y7

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini117 – 191BTBAdd BLAST75

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3840, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000007975

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_036245_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q7Z5Y7

Identification of Orthologs from Complete Genome Data

More...
OMAi
XALLHEL

Database of Orthologous Groups

More...
OrthoDBi
390051at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q7Z5Y7

TreeFam database of animal gene trees

More...
TreeFami
TF314369

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.30.710.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR000210, BTB/POZ_dom
IPR039886, BTBD10/KCTD20
IPR039885, BTBD10/KCTD20_BTB/POZ
IPR011333, SKP1/BTB/POZ_sf

The PANTHER Classification System

More...
PANTHERi
PTHR21637, PTHR21637, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF16017, BTB_3, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00225, BTB, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF54695, SSF54695, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 5 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q7Z5Y7-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MNVHRGSDSD RLLRQEASCL VDDTLAVAQE KEANSLASSG PHNLTYPLGP
60 70 80 90 100
RNEDLSLDYA SQPANLQFPH IMPLAEDIKG SCFQSGNKRN HEPFIAPERF
110 120 130 140 150
GNSSVGFGSN SHSQAPEKVT LLVDGTRFVV NPQIFTAHPD TMLGRMFGPG
160 170 180 190 200
REYNFTRPNE KGEYEIAEGI SATVFRTVLD YYKTGIINCP DGISIPDLRD
210 220 230 240 250
TCDYLCINFD FNTIRCQDLS ALLHELSNDG AHKQFDHYLE ELILPIMVGC
260 270 280 290 300
AKKGERECHI VVLTDEDSVD WDEDHPPPMG EEYSQILYSS KLYRFFKYIE
310 320 330 340 350
NRDVAKTVLK ERGLKNIRIG IEGYPTCKEK IKRRPGGRSE VIYNYVQRPF
360 370 380 390 400
IQMSWEKEEG KSRHVDFQCV RSKSLTNLVA AGDDVLEDQE ILMHHPPQVD
410
ELDRLNAPLS QMASNDFQD
Length:419
Mass (Da):47,480
Last modified:October 1, 2003 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i71B5D35EA02714EC
GO
Isoform 2 (identifier: Q7Z5Y7-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     54-54: D → G
     55-220: Missing.

Show »
Length:253
Mass (Da):28,892
Checksum:iFD685CD0E4995090
GO
Isoform 3 (identifier: Q7Z5Y7-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-145: Missing.

Show »
Length:274
Mass (Da):31,669
Checksum:i6C4ABB9B0D986630
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
H7BXH0H7BXH0_HUMAN
BTB/POZ domain-containing protein K...
KCTD20
127Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F8WF75F8WF75_HUMAN
BTB/POZ domain-containing protein K...
KCTD20
92Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
C9JY11C9JY11_HUMAN
BTB/POZ domain-containing protein K...
KCTD20
109Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
C9J5B3C9J5B3_HUMAN
BTB/POZ domain-containing protein K...
KCTD20
87Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
C9J624C9J624_HUMAN
BTB/POZ domain-containing protein K...
KCTD20
97Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti70H → R in CAH10583 (PubMed:17974005).Curated1
Sequence conflicti205L → P in CAH10583 (PubMed:17974005).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_028854171S → T1 PublicationCorresponds to variant dbSNP:rs2239808Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0556691 – 145Missing in isoform 3. 1 PublicationAdd BLAST145
Alternative sequenceiVSP_02127754D → G in isoform 2. 1 Publication1
Alternative sequenceiVSP_02127855 – 220Missing in isoform 2. 1 PublicationAdd BLAST166

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AY305862 mRNA Translation: AAP74385.1
AK302861 mRNA Translation: BAG64045.1
AK304377 mRNA Translation: BAG65215.1
AL136135 Genomic DNA No translation available.
Z85986 Genomic DNA No translation available.
CH471081 Genomic DNA Translation: EAX03892.1
BC023525 mRNA Translation: AAH23525.1
AL832381 mRNA Translation: CAH10583.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS4821.1 [Q7Z5Y7-1]
CCDS69096.1 [Q7Z5Y7-2]
CCDS69097.1 [Q7Z5Y7-3]

NCBI Reference Sequences

More...
RefSeqi
NP_001273508.1, NM_001286579.1 [Q7Z5Y7-2]
NP_001273509.1, NM_001286580.1 [Q7Z5Y7-3]
NP_775833.2, NM_173562.4 [Q7Z5Y7-1]
XP_005248997.1, XM_005248940.4 [Q7Z5Y7-1]
XP_006715086.1, XM_006715023.2 [Q7Z5Y7-1]
XP_011512700.1, XM_011514398.2 [Q7Z5Y7-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000373731; ENSP00000362836; ENSG00000112078 [Q7Z5Y7-1]
ENST00000449081; ENSP00000412205; ENSG00000112078 [Q7Z5Y7-2]
ENST00000536244; ENSP00000439118; ENSG00000112078 [Q7Z5Y7-3]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
222658

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:222658

UCSC genome browser

More...
UCSCi
uc003ome.4, human [Q7Z5Y7-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY305862 mRNA Translation: AAP74385.1
AK302861 mRNA Translation: BAG64045.1
AK304377 mRNA Translation: BAG65215.1
AL136135 Genomic DNA No translation available.
Z85986 Genomic DNA No translation available.
CH471081 Genomic DNA Translation: EAX03892.1
BC023525 mRNA Translation: AAH23525.1
AL832381 mRNA Translation: CAH10583.1
CCDSiCCDS4821.1 [Q7Z5Y7-1]
CCDS69096.1 [Q7Z5Y7-2]
CCDS69097.1 [Q7Z5Y7-3]
RefSeqiNP_001273508.1, NM_001286579.1 [Q7Z5Y7-2]
NP_001273509.1, NM_001286580.1 [Q7Z5Y7-3]
NP_775833.2, NM_173562.4 [Q7Z5Y7-1]
XP_005248997.1, XM_005248940.4 [Q7Z5Y7-1]
XP_006715086.1, XM_006715023.2 [Q7Z5Y7-1]
XP_011512700.1, XM_011514398.2 [Q7Z5Y7-1]

3D structure databases

SMRiQ7Z5Y7
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi128809, 10 interactors
IntActiQ7Z5Y7, 8 interactors
STRINGi9606.ENSP00000362836

PTM databases

iPTMnetiQ7Z5Y7
PhosphoSitePlusiQ7Z5Y7

Genetic variation databases

BioMutaiKCTD20
DMDMi74750149

Proteomic databases

EPDiQ7Z5Y7
jPOSTiQ7Z5Y7
MassIVEiQ7Z5Y7
MaxQBiQ7Z5Y7
PaxDbiQ7Z5Y7
PeptideAtlasiQ7Z5Y7
PRIDEiQ7Z5Y7
ProteomicsDBi26368
69360 [Q7Z5Y7-1]
69361 [Q7Z5Y7-2]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
29679, 58 antibodies

The DNASU plasmid repository

More...
DNASUi
222658

Genome annotation databases

EnsembliENST00000373731; ENSP00000362836; ENSG00000112078 [Q7Z5Y7-1]
ENST00000449081; ENSP00000412205; ENSG00000112078 [Q7Z5Y7-2]
ENST00000536244; ENSP00000439118; ENSG00000112078 [Q7Z5Y7-3]
GeneIDi222658
KEGGihsa:222658
UCSCiuc003ome.4, human [Q7Z5Y7-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
222658
DisGeNETi222658

GeneCards: human genes, protein and diseases

More...
GeneCardsi
KCTD20
HGNCiHGNC:21052, KCTD20
HPAiENSG00000112078, Low tissue specificity
MIMi615932, gene
neXtProtiNX_Q7Z5Y7
OpenTargetsiENSG00000112078
PharmGKBiPA134913479
VEuPathDBiHostDB:ENSG00000112078

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG3840, Eukaryota
GeneTreeiENSGT00390000007975
HOGENOMiCLU_036245_0_0_1
InParanoidiQ7Z5Y7
OMAiXALLHEL
OrthoDBi390051at2759
PhylomeDBiQ7Z5Y7
TreeFamiTF314369

Enzyme and pathway databases

PathwayCommonsiQ7Z5Y7

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

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BioGRID-ORCSi
222658, 5 hits in 1022 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
KCTD20, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
222658
PharosiQ7Z5Y7, Tdark

Protein Ontology

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PROi
PR:Q7Z5Y7
RNActiQ7Z5Y7, protein

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSG00000112078, Expressed in amniotic fluid and 226 other tissues
ExpressionAtlasiQ7Z5Y7, baseline and differential
GenevisibleiQ7Z5Y7, HS

Family and domain databases

Gene3Di3.30.710.10, 1 hit
InterProiView protein in InterPro
IPR000210, BTB/POZ_dom
IPR039886, BTBD10/KCTD20
IPR039885, BTBD10/KCTD20_BTB/POZ
IPR011333, SKP1/BTB/POZ_sf
PANTHERiPTHR21637, PTHR21637, 1 hit
PfamiView protein in Pfam
PF16017, BTB_3, 1 hit
SMARTiView protein in SMART
SM00225, BTB, 1 hit
SUPFAMiSSF54695, SSF54695, 1 hit

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiKCD20_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q7Z5Y7
Secondary accession number(s): B4DZD3
, B4E2Q3, F5H3T3, Q5W105, Q69YQ7, Q8IZ55
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: October 1, 2003
Last modified: September 29, 2021
This is version 135 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 6
    Human chromosome 6: entries, gene names and cross-references to MIM
  2. Human entries with genetic variants
    List of human entries with genetic variants
  3. Human variants curated from literature reports
    Index of human variants curated from literature reports
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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