UniProtKB - Q7Z5W8 (Q7Z5W8_HUMAN)
Protein
Submitted name:
ACACA protein
Gene
ACACA
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- ligase activity Source: UniProtKB-KW
Keywordsi
Molecular function | LigaseARBA annotation |
Names & Taxonomyi
Protein namesi | Submitted name: ACACA proteinImported |
Gene namesi | Name:ACACAImported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 1 – 258 | CoA carboxyltransferase N-terminalInterPro annotationAdd BLAST | 258 | |
Domaini | 262 – 578 | CoA carboxyltransferase C-terminalInterPro annotationAdd BLAST | 317 |
Phylogenomic databases
OrthoDBi | 156081at2759 |
Family and domain databases
InterProi | View protein in InterPro IPR034733, AcCoA_carboxyl IPR029045, ClpP/crotonase-like_dom_sf IPR011763, COA_CT_C IPR011762, COA_CT_N |
Pfami | View protein in Pfam PF01039, Carboxyl_trans, 1 hit |
SUPFAMi | SSF52096, SSF52096, 2 hits |
PROSITEi | View protein in PROSITE PS50989, COA_CT_CTER, 1 hit PS50980, COA_CT_NTER, 1 hit |
i Sequence
Sequence statusi: Fragment.
Q7Z5W8-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
IGMVAWKMTF KSPEYPEGRD IIVIGNDITY RIGSFGPQED LLFLRASELA
60 70 80 90 100
RAEGIPRIYV SANSGARIGL AEEIRHMFHV AWVDPEDPYK GYRYLYLTPQ
110 120 130 140 150
DYKRVSALNS VHCEHVEDEG ESRYKITDII GKEEGIGPEN LRGSGMIAGE
160 170 180 190 200
SSLAYNEIIT ISLVTCRAIG IGAYLVRLGQ RTIQVENSHL ILTGAGALNK
210 220 230 240 250
VLGREVYTSN NQLGGIQIMH NNGVTHCTVC DDFEGVFTVL HWLSYMPKSV
260 270 280 290 300
HSSVPLLNSK DPIDRIIEFV PTKTPYDPRW MLAGRPHPTQ KGQWLSGFFD
310 320 330 340 350
YGSFSEIMQP WAQTVVVGRA RLGGIPVGVV AVETRTVELS IPADPANLDS
360 370 380 390 400
EAKIIQQAGQ VWFPDSAFKT YQAIKDFNRE GLPLMVFANW RGFSGGMKDM
410 420 430 440 450
YDQVLKFGAY IVDGLRECCQ PVLVYIPPQA ELRGGSWVVI DSSINPRHME
460 470 480 490 500
MYADRESRGS VLEPEGTVEI KFRRKDLVKT MRRVDPVYIH LAERLGTPEL
510 520 530 540 550
STAERKELEN KLKEREEFLI PIYHQVAVQF ADLHDTPGRM QEKGVISDIL
560 570 580 590 600
DWKTSRTFFY WRLRRLLLED LVKKKIHNAN PELTDGQIQA MLRRWFVEVE
610 620 630 640 650
GTVKAYVWDN NKDLAEWLEK QLTEEDGVHS VIEENIKCIS RDYVLKQIRS
660 670 680 690
LVQANPEVAM DSIIHMTQHI SPTQRAEVIR ILSTMDSPST
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 1 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC031485 mRNA Translation: AAH31485.1 |
RefSeqi | NP_942134.1, NM_198837.1 NP_942135.1, NM_198838.1 |
Genome annotation databases
GeneIDi | 31 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC031485 mRNA Translation: AAH31485.1 |
RefSeqi | NP_942134.1, NM_198837.1 NP_942135.1, NM_198838.1 |
3D structure databases
SMRi | Q7Z5W8 |
ModBasei | Search... |
Proteomic databases
PeptideAtlasi | Q7Z5W8 |
Genome annotation databases
GeneIDi | 31 |
Organism-specific databases
CTDi | 31 |
PharmGKBi | PA24421 |
Phylogenomic databases
OrthoDBi | 156081at2759 |
Miscellaneous databases
BioGRID-ORCSi | 31, 197 hits in 854 CRISPR screens |
ChiTaRSi | ACACA, human |
GenomeRNAii | 31 |
Gene expression databases
Genevisiblei | Q7Z5W8, HS |
Family and domain databases
InterProi | View protein in InterPro IPR034733, AcCoA_carboxyl IPR029045, ClpP/crotonase-like_dom_sf IPR011763, COA_CT_C IPR011762, COA_CT_N |
Pfami | View protein in Pfam PF01039, Carboxyl_trans, 1 hit |
SUPFAMi | SSF52096, SSF52096, 2 hits |
PROSITEi | View protein in PROSITE PS50989, COA_CT_CTER, 1 hit PS50980, COA_CT_NTER, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q7Z5W8_HUMAN | |
Accessioni | Q7Z5W8Primary (citable) accession number: Q7Z5W8 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | October 1, 2003 |
Last sequence update: | October 1, 2003 | |
Last modified: | December 2, 2020 | |
This is version 88 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |