Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 133 (13 Feb 2019)
Sequence version 3 (21 Aug 2007)
Previous versions | rss
Other tutorials and videosHelp videoFeedback
Protein

Cytoplasmic polyadenylation element-binding protein 2

Gene

CPEB2

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May play a role in translational regulation of stored mRNAs in transcriptionally inactive haploid spermatids. Binds to poly(U) RNA oligomers (By similarity). Required for cell cycle progression, specifically for the transition from metaphase to anaphase (PubMed:26398195).By similarity1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionRNA-binding
Biological processTranslation regulation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Cytoplasmic polyadenylation element-binding protein 2
Short name:
CPE-BP2
Short name:
CPE-binding protein 2
Short name:
hCPEB-2
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:CPEB2
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 4

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000137449.15

Human Gene Nomenclature Database

More...
HGNCi
HGNC:21745 CPEB2

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
610605 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q7Z5Q1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
132864

Open Targets

More...
OpenTargetsi
ENSG00000137449

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134864048

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
CPEB2

Domain mapping of disease mutations (DMDM)

More...
DMDMi
158937340

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002692591 – 589Cytoplasmic polyadenylation element-binding protein 2Add BLAST589

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei89PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q7Z5Q1

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q7Z5Q1

PeptideAtlas

More...
PeptideAtlasi
Q7Z5Q1

PRoteomics IDEntifications database

More...
PRIDEi
Q7Z5Q1

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q7Z5Q1

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q7Z5Q1

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000137449 Expressed in 207 organ(s), highest expression level in brain

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q7Z5Q1 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q7Z5Q1 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA072513

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with TENT2/GLD2.By similarity

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
126338, 26 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000443985

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
Q7Z5Q1

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q7Z5Q1

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini332 – 423RRM 1PROSITE-ProRule annotationAdd BLAST92
Domaini440 – 522RRM 2PROSITE-ProRule annotationAdd BLAST83

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi2 – 93Pro-richAdd BLAST92

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the RRM CPEB family.Curated

Keywords - Domaini

Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0129 Eukaryota
ENOG410Y1XZ LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000160357

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000290661

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG058010

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q7Z5Q1

KEGG Orthology (KO)

More...
KOi
K02602

Identification of Orthologs from Complete Genome Data

More...
OMAi
FCGEAYG

Database of Orthologous Groups

More...
OrthoDBi
1075356at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q7Z5Q1

TreeFam database of animal gene trees

More...
TreeFami
TF317658

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.30.40.130, 1 hit
3.30.70.330, 2 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR032296 CEBP_ZZ
IPR038446 CEBP_ZZ_sf
IPR034819 CPEB
IPR012677 Nucleotide-bd_a/b_plait_sf
IPR035979 RBD_domain_sf
IPR000504 RRM_dom

The PANTHER Classification System

More...
PANTHERi
PTHR12566 PTHR12566, 2 hits

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF16366 CEBP_ZZ, 1 hit
PF16367 RRM_7, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00360 RRM, 2 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF54928 SSF54928, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50102 RRM, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (8+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 8 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 8 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q7Z5Q1-2) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MPPPSPDSEN GFYPGLPSSM NPAFFPSFSP VSPHGCTGLS VPTSGGGGGG
60 70 80 90 100
FGGPFSATAV PPPPPPAMNI PQQQPPPPAA PQQPQSRRSP VSPQLQQQHQ
110 120 130 140 150
AAAAAFLQQR NSYNHHQPLL KQSPWSNHQS SGWGTGSMSW GAMHGRDHRR
160 170 180 190 200
TGNMGIPGTM NQISPLKKPF SGNVIAPPKF TRSTPSLTPK SWIEDNVFRT
210 220 230 240 250
DNNSNTLLPL QVRSSLQLPA WGSDSLQDSW CTAAGTSRID QDRSRMYDSL
260 270 280 290 300
NMHSLENSLI DIMRAEHDPL KGRLSYPHPG TDNLLMLNGR SSLFPIDDGL
310 320 330 340 350
LDDGHSDQVG VLNSPTCYSA HQNGERIERF SRKVFVGGLP PDIDEDEITA
360 370 380 390 400
SFRRFGPLVV DWPHKAESKS YFPPKGYAFL LFQEESSVQA LIDACIEEDG
410 420 430 440 450
KLYLCVSSPT IKDKPVQIRP WNLSDSDFVM DGSQPLDPRK TIFVGGVPRP
460 470 480 490 500
LRAVELAMIM DRLYGGVCYA GIDTDPELKY PKGAGRVAFS NQQSYIAAIS
510 520 530 540 550
ARFVQLQHGD IDKRVEVKPY VLDDQMCDEC QGARCGGKFA PFFCANVTCL
560 570 580
QYYCEFCWAN IHSRAGREFH KPLVKEGADR PRQIHFRWN
Length:589
Mass (Da):64,944
Last modified:August 21, 2007 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iE0A16772D2E3091A
GO
Isoform 2 (identifier: Q7Z5Q1-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     43-64: Missing.
     288-288: N → NARSYGRRR

Show »
Length:575
Mass (Da):64,093
Checksum:i0BC308E83DB1D799
GO
Isoform 3 (identifier: Q7Z5Q1-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     214-241: SSLQLPAWGSDSLQDSWCTAAGTSRIDQ → M

Show »
Length:562
Mass (Da):62,112
Checksum:i269754FE66F5B647
GO
Isoform 4 (identifier: Q7Z5Q1-5) [UniParc]FASTAAdd to basket
Also known as: CPEB2b

The sequence of this isoform differs from the canonical sequence as follows:
     212-241: Missing.

Show »
Length:559
Mass (Da):61,726
Checksum:i9465D16A0203B6A9
GO
Isoform 5 (identifier: Q7Z5Q1-6) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     212-241: Missing.
     288-288: N → NARSYGRRR

Show »
Length:567
Mass (Da):62,729
Checksum:i17A2D7994BFAADA6
GO
Isoform 6 (identifier: Q7Z5Q1-7) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     43-64: Missing.
     214-241: SSLQLPAWGSDSLQDSWCTAAGTSRIDQ → M
     288-288: N → NARSYGRRR

Show »
Length:548
Mass (Da):61,261
Checksum:i2A5A0BDA3FCCDD06
GO
Isoform 7 (identifier: Q7Z5Q1-8) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-1: M → MRDFGFGVLQ...GGSGGSLSAM
     214-241: SSLQLPAWGSDSLQDSWCTAAGTSRIDQ → M
     288-288: N → NARSYGRRR

Note: No experimental confirmation available. Gene prediction based on EST data.
Show »
Length:1,007
Mass (Da):106,972
Checksum:iE71487A7D5AA3EE4
GO
Isoform 8 (identifier: Q7Z5Q1-9) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-1: M → MRDFGFGVLQ...GGSGGSLSAM
     288-288: N → NARSYGRRR

Note: No experimental confirmation available. Gene prediction based on EST data.
Show »
Length:1,034
Mass (Da):109,804
Checksum:i1802DC868AB9211C
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
J3KN18J3KN18_HUMAN
Cytoplasmic polyadenylation element...
CPEB2
597Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H0Y9D9H0Y9D9_HUMAN
Cytoplasmic polyadenylation element...
CPEB2
167Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti50G → GG in AAI03942 (PubMed:15815621).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0556701M → MRDFGFGVLQTAPLRSSSPG PLFCGEAYGPYAVGSVNPLP SATPFGPLSPPPLPVTGFLE AASPFSVPLGGGAGSPAAAA SSSSPFLAHQQTMQDELLLG LTQQPARPLSGAAATEKLPD HHPGGGTIAGVTHLLPSQDF KPSLHHPSSSSASSCCCCRT SSPQDFSKRQQQQLSSQKRK EFSPPHLPHPPDSKPPPPPP PLHCPGRFSPPPPPAGPLLQ PAQLAQRQQQQPPQQFSLLH QQHLSPQDFAPRQRPADLPP LPQLPPSPPAAPRRRHGGAG SPRKTPAAGEGSAAESPNAG LASSTPVNPAPGSMESPNHP LLNSPSNLLPGGALGAGAFS SLQSPDLPHPGGGGGGGGGG PPGGGGGGGSASPPPLPGFG TPWSVQTASPPPQPQQPPPT QPQQQPPPPQQPPQPQPQPP GSSATTPGGGSGGSLSAM in isoform 7 and isoform 8. Curated1
Alternative sequenceiVSP_02203043 – 64Missing in isoform 2 and isoform 6. 1 PublicationAdd BLAST22
Alternative sequenceiVSP_022031212 – 241Missing in isoform 4 and isoform 5. 2 PublicationsAdd BLAST30
Alternative sequenceiVSP_022032214 – 241SSLQL…SRIDQ → M in isoform 3, isoform 6 and isoform 7. 1 PublicationAdd BLAST28
Alternative sequenceiVSP_027372288N → NARSYGRRR in isoform 2, isoform 5, isoform 6, isoform 7 and isoform 8. 1 Publication1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AY247744 mRNA Translation: AAP37585.1
AY255519 mRNA Translation: AAP41553.1
AC098829 Genomic DNA No translation available.
AC105289 Genomic DNA No translation available.
AC114749 Genomic DNA No translation available.
BC103939 mRNA Translation: AAI03940.2
BC103940 mRNA Translation: AAI03941.1
BC103941 mRNA Translation: AAI03942.1
BC103942 mRNA Translation: AAI03943.1
BC105925 mRNA Translation: AAI05926.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS56325.1 [Q7Z5Q1-9]
CCDS56326.1 [Q7Z5Q1-8]

NCBI Reference Sequences

More...
RefSeqi
NP_001170852.1, NM_001177381.1 [Q7Z5Q1-8]
NP_001170853.1, NM_001177382.1 [Q7Z5Q1-9]
NP_001170854.1, NM_001177383.1
NP_001170855.1, NM_001177384.1
NP_872291.2, NM_182485.2
NP_872587.2, NM_182646.2

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.656937

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000345451; ENSP00000334058; ENSG00000137449 [Q7Z5Q1-5]
ENST00000382395; ENSP00000371832; ENSG00000137449 [Q7Z5Q1-6]
ENST00000382401; ENSP00000371838; ENSG00000137449 [Q7Z5Q1-4]
ENST00000442003; ENSP00000414270; ENSG00000137449 [Q7Z5Q1-8]
ENST00000507071; ENSP00000424084; ENSG00000137449 [Q7Z5Q1-2]
ENST00000538197; ENSP00000443985; ENSG00000137449 [Q7Z5Q1-9]
ENST00000634696; ENSP00000488925; ENSG00000283087 [Q7Z5Q1-2]
ENST00000634867; ENSP00000489160; ENSG00000283087 [Q7Z5Q1-5]
ENST00000635061; ENSP00000489427; ENSG00000283087 [Q7Z5Q1-9]
ENST00000635093; ENSP00000489406; ENSG00000283087 [Q7Z5Q1-6]
ENST00000635362; ENSP00000489336; ENSG00000283087 [Q7Z5Q1-8]
ENST00000635651; ENSP00000489362; ENSG00000283087 [Q7Z5Q1-4]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
132864

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:132864

UCSC genome browser

More...
UCSCi
uc003gnk.2 human [Q7Z5Q1-2]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY247744 mRNA Translation: AAP37585.1
AY255519 mRNA Translation: AAP41553.1
AC098829 Genomic DNA No translation available.
AC105289 Genomic DNA No translation available.
AC114749 Genomic DNA No translation available.
BC103939 mRNA Translation: AAI03940.2
BC103940 mRNA Translation: AAI03941.1
BC103941 mRNA Translation: AAI03942.1
BC103942 mRNA Translation: AAI03943.1
BC105925 mRNA Translation: AAI05926.1
CCDSiCCDS56325.1 [Q7Z5Q1-9]
CCDS56326.1 [Q7Z5Q1-8]
RefSeqiNP_001170852.1, NM_001177381.1 [Q7Z5Q1-8]
NP_001170853.1, NM_001177382.1 [Q7Z5Q1-9]
NP_001170854.1, NM_001177383.1
NP_001170855.1, NM_001177384.1
NP_872291.2, NM_182485.2
NP_872587.2, NM_182646.2
UniGeneiHs.656937

3D structure databases

ProteinModelPortaliQ7Z5Q1
SMRiQ7Z5Q1
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi126338, 26 interactors
STRINGi9606.ENSP00000443985

PTM databases

iPTMnetiQ7Z5Q1
PhosphoSitePlusiQ7Z5Q1

Polymorphism and mutation databases

BioMutaiCPEB2
DMDMi158937340

Proteomic databases

jPOSTiQ7Z5Q1
PaxDbiQ7Z5Q1
PeptideAtlasiQ7Z5Q1
PRIDEiQ7Z5Q1

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000345451; ENSP00000334058; ENSG00000137449 [Q7Z5Q1-5]
ENST00000382395; ENSP00000371832; ENSG00000137449 [Q7Z5Q1-6]
ENST00000382401; ENSP00000371838; ENSG00000137449 [Q7Z5Q1-4]
ENST00000442003; ENSP00000414270; ENSG00000137449 [Q7Z5Q1-8]
ENST00000507071; ENSP00000424084; ENSG00000137449 [Q7Z5Q1-2]
ENST00000538197; ENSP00000443985; ENSG00000137449 [Q7Z5Q1-9]
ENST00000634696; ENSP00000488925; ENSG00000283087 [Q7Z5Q1-2]
ENST00000634867; ENSP00000489160; ENSG00000283087 [Q7Z5Q1-5]
ENST00000635061; ENSP00000489427; ENSG00000283087 [Q7Z5Q1-9]
ENST00000635093; ENSP00000489406; ENSG00000283087 [Q7Z5Q1-6]
ENST00000635362; ENSP00000489336; ENSG00000283087 [Q7Z5Q1-8]
ENST00000635651; ENSP00000489362; ENSG00000283087 [Q7Z5Q1-4]
GeneIDi132864
KEGGihsa:132864
UCSCiuc003gnk.2 human [Q7Z5Q1-2]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
132864
DisGeNETi132864
EuPathDBiHostDB:ENSG00000137449.15

GeneCards: human genes, protein and diseases

More...
GeneCardsi
CPEB2
HGNCiHGNC:21745 CPEB2
HPAiHPA072513
MIMi610605 gene
neXtProtiNX_Q7Z5Q1
OpenTargetsiENSG00000137449
PharmGKBiPA134864048

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG0129 Eukaryota
ENOG410Y1XZ LUCA
GeneTreeiENSGT00940000160357
HOGENOMiHOG000290661
HOVERGENiHBG058010
InParanoidiQ7Z5Q1
KOiK02602
OMAiFCGEAYG
OrthoDBi1075356at2759
PhylomeDBiQ7Z5Q1
TreeFamiTF317658

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
CPEB2 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
132864

Protein Ontology

More...
PROi
PR:Q7Z5Q1

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000137449 Expressed in 207 organ(s), highest expression level in brain
ExpressionAtlasiQ7Z5Q1 baseline and differential
GenevisibleiQ7Z5Q1 HS

Family and domain databases

Gene3Di3.30.40.130, 1 hit
3.30.70.330, 2 hits
InterProiView protein in InterPro
IPR032296 CEBP_ZZ
IPR038446 CEBP_ZZ_sf
IPR034819 CPEB
IPR012677 Nucleotide-bd_a/b_plait_sf
IPR035979 RBD_domain_sf
IPR000504 RRM_dom
PANTHERiPTHR12566 PTHR12566, 2 hits
PfamiView protein in Pfam
PF16366 CEBP_ZZ, 1 hit
PF16367 RRM_7, 1 hit
SMARTiView protein in SMART
SM00360 RRM, 2 hits
SUPFAMiSSF54928 SSF54928, 1 hit
PROSITEiView protein in PROSITE
PS50102 RRM, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCPEB2_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q7Z5Q1
Secondary accession number(s): E7EPM3
, F5H160, Q3B8N6, Q3MI89, Q3MI90, Q3MI92, Q7Z5Q0
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 12, 2006
Last sequence update: August 21, 2007
Last modified: February 13, 2019
This is version 133 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human chromosome 4
    Human chromosome 4: entries, gene names and cross-references to MIM
  3. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again