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Entry version 99 (08 May 2019)
Sequence version 3 (08 Jun 2016)
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Protein

Mucin-19

Gene

MUC19

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May function in ocular mucus homeostasis.1 Publication

Caution

According to the Genome Reference Consortium, the reference genome GRCh38/hg38 is in conflict with the sequence shown here.Curated

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-5083625 Defective GALNT3 causes familial hyperphosphatemic tumoral calcinosis (HFTC)
R-HSA-5083632 Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)
R-HSA-5083636 Defective GALNT12 causes colorectal cancer 1 (CRCS1)
R-HSA-5621480 Dectin-2 family
R-HSA-913709 O-linked glycosylation of mucins
R-HSA-977068 Termination of O-glycan biosynthesis

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Mucin-19
Short name:
MUC-19
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:MUC19
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unplaced

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:14362 MUC19

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
612170 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q7Z5P9

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Secreted

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
283463

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
HGNC:14362

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 21Sequence analysisAdd BLAST21
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000034266422 – 8384Mucin-19Add BLAST8363

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi502 ↔ 510PROSITE-ProRule annotation
Disulfide bondi8288 ↔ 8339PROSITE-ProRule annotation
Disulfide bondi8306 ↔ 8353PROSITE-ProRule annotation
Disulfide bondi8315 ↔ 8369PROSITE-ProRule annotation
Disulfide bondi8319 ↔ 8371PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bond

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q7Z5P9

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q7Z5P9

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q7Z5P9

PeptideAtlas

More...
PeptideAtlasi
Q7Z5P9

PRoteomics IDEntifications database

More...
PRIDEi
Q7Z5P9

ProteomicsDB human proteome resource

More...
ProteomicsDBi
69340
69341 [Q7Z5P9-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q7Z5P9

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q7Z5P9

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed corneal epithelial cells, conjunctival goblet and epithelial cells and lacrimal gland cells (at protein level). Expressed by mucous cells of the submandibular gland and submucosal gland of the trachea. Expressed by middle ear epithelial cells.3 Publications

<p>This subsection of the ‘Expression’ section reports the experimentally proven effects of inducers and repressors (usually chemical compounds or environmental factors) on the level of protein (or mRNA) expression (up-regulation, down-regulation, constitutive expression).<p><a href='/help/induction' target='_top'>More...</a></p>Inductioni

Down-regulated in Sjoegren syndrome patients (at protein level).1 Publication

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q7Z5P9

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini479 – 681VWFD 1PROSITE-ProRule annotationAdd BLAST203
Domaini815 – 1023VWFD 2PROSITE-ProRule annotationAdd BLAST209
Domaini1275 – 1484VWFD 3PROSITE-ProRule annotationAdd BLAST210
Domaini8159 – 8225VWFCPROSITE-ProRule annotationAdd BLAST67
Domaini8288 – 8376CTCKPROSITE-ProRule annotationAdd BLAST89

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni2238 – 6086Approximate repeats of G-V-T-G-T-T-G-P-S-ACuratedAdd BLAST3849

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi195 – 441Gly-richPROSITE-ProRule annotationAdd BLAST247
Compositional biasi273 – 451Ser-richPROSITE-ProRule annotationAdd BLAST179
Compositional biasi1638 – 8149Thr-richPROSITE-ProRule annotationAdd BLAST6512

Keywords - Domaini

Repeat, Signal

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IR85 Eukaryota
ENOG410ZXRK LUCA

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q7Z5P9

KEGG Orthology (KO)

More...
KOi
K22020

Database of Orthologous Groups

More...
OrthoDBi
12226at2759

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR006207 Cys_knot_C
IPR036084 Ser_inhib-like_sf
IPR002919 TIL_dom
IPR014853 Unchr_dom_Cys-rich
IPR001007 VWF_dom
IPR001846 VWF_type-D

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF08742 C8, 2 hits
PF01826 TIL, 1 hit
PF00094 VWD, 3 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00832 C8, 2 hits
SM00041 CT, 1 hit
SM00214 VWC, 3 hits
SM00215 VWC_out, 2 hits
SM00216 VWD, 3 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF57567 SSF57567, 3 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS01185 CTCK_1, 1 hit
PS01225 CTCK_2, 1 hit
PS50184 VWFC_2, 1 hit
PS51233 VWFD, 3 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform 1 (identifier: Q7Z5P9-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MKLILWYLVV ALWCFFKDVE ALLYRQKSDG KIAASRSGGF SYGSSSSGDL
60 70 80 90 100
DRKKPLFSLE FGSPGETEDK SRQRQDAGSP KSEDTPAGGF FNSSSSSGDS
110 120 130 140 150
DRTKPFFSLG LGAPGKAEDK SGDSQDAGGS KSEDTPPGGF FYGSSSSGDS
160 170 180 190 200
DKKKPLFSFE FGATGEDEDK SRERWDAGNS RSEDSPADST NTRYGAGFSS
210 220 230 240 250
SGASLDVGFG WGISDEKGLE VSKADGRETR GSGSAGGETI VFGPDAGSSV
260 270 280 290 300
GTGSSGLKLG AGKGDAAFGF EVSDSNSFGD TGISSKTVEG NQTSSSGGSV
310 320 330 340 350
SIDLGDTSFR SENQFVGGGS LNSISNLWDS GQEGFGINEI GGNGMSGSVS
360 370 380 390 400
AEAGFKGFGS DSSSSGDSSA RNGFENSSGI SEDSGVILGS SDQHEVELSR
410 420 430 440 450
TGGNRKRSSD PDEAGNLSPG SDVSDSGGNT WSSDSGSGGG GVTSSSEYST
460 470 480 490 500
SGPLNTPEKG SHIPEATPKY SETNAIIGEI STWSKGAYKS FNGRIFFFES
510 520 530 540 550
SCPYTFCRHC IESGGDFNIE IKRNNDSEIE KITVLIDNND VSIFGDTILV
560 570 580 590 600
NGESVQIPYN NKLIHIKKYG EHNVLNSRRG ILTLMWDKNN KLSLTLHKQY
610 620 630 640 650
PTCGLCGNFN STPGQDINEH IANSKIPGDC PNAVGKSYEV CEDGIQHCNK
660 670 680 690 700
IIGTYFEKCG KVAALSNDYK MICIDEYCQT RDKTSTCDTY SELSRLCASD
710 720 730 740 750
GPGTFESWRS DSDVVCGTQR CPEQHIYKEC GPSNPATCSN VAPFQDSECV
760 770 780 790 800
SGCTCPEGYL LDDIGEKGKC VLKAECPCES SGTVYQPGEV REGPCGSQCT
810 820 830 840 850
CQDAKWSCTE ALCPGRCKVE GSSLTTFDGV KYNFPGNCHF LAVHNEDWSI
860 870 880 890 900
SVELRPCPSG QTGTCLNSVT LLLNSSVPVD KYVFNSDGTV TNDKIRNQGY
910 920 930 940 950
YYSDKIQIFN ASSSYLQVET YFHVKLQIQI VPVMQLYVSM PPNQFTDTVG
960 970 980 990 1000
LCGSYNNKAE DDFMSSQNIL EKTSQAFANS WEMMSCPKGN PSSCISIEKE
1010 1020 1030 1040 1050
KFAERHCGIL LDSSGPLASC HPIVNPKPYH EECKKYTCTC ENSQDCLCTI
1060 1070 1080 1090 1100
LGNYVKACAE KETYIVGWRT GLCEHSCPSG LVFKYNVKAC NSSCRSLSER
1110 1120 1130 1140 1150
DRSCDVEDVP VDGCTCPDAM YQNNEGNCVL KSQCDCYIND EVMQPGKLIH
1160 1170 1180 1190 1200
IDDNKCVCRD GILLCQIPID LTLQNCSGGA EYVDCSDPKA QRRTNRTCST
1210 1220 1230 1240 1250
RNIPVFDENL PCKRGCFCPE GMVRNSKGIC VFPNDCPCSF GGREYDEGSV
1260 1270 1280 1290 1300
TSVGCNECTC IKGSWSCTQN ECQTICHIYG EGHVRTFDGK SYSFDGLCQY
1310 1320 1330 1340 1350
SFLEDYCGHE NGTFRILTES VPCCEDGLTC SRKIIVAFQD QNIVLQDGKV
1360 1370 1380 1390 1400
TAVKSTESKK CELNANAYSI HTVGLYLILK FQNGIIVIWD KNTRLSVILD
1410 1420 1430 1440 1450
PNWNGKVCGL CGNNNGDLKD DFTTRYSSVA SGALEFGNSW KTSQECSDTV
1460 1470 1480 1490 1500
AQTFPCDSNP YCKAWAVRKC EILRDSTFRD CHNKVDPSAY HDACIEEACA
1510 1520 1530 1540 1550
CDMEGKYLGF CTAVAMYAEA CSAVGVCVSW RKPNLCPVYC DYYNAPGECR
1560 1570 1580 1590 1600
WHYEPCGTVT AKTCKDQLVG QKFSSLLEGC YAKCPDSAPY LDENTMKCVS
1610 1620 1630 1640 1650
LSECSCFYND VIPAGGVIED NCGRTCYCIA GQLECSETAP TNSTFAVSTT
1660 1670 1680 1690 1700
TATTILSTGA AITLVTGGPS TAASIPAITT SSSETTGTTL GPLTEPFTTG
1710 1720 1730 1740 1750
ITETSVPIIS TSGNAGMTGV VSPTVTGASG MAGTTGGVDA ATTGAASENT
1760 1770 1780 1790 1800
SERAGTPRVS GETPAVGGGS TPGEAGPGAT VSGSTGVSAG SITASPGASA
1810 1820 1830 1840 1850
TSSESSKSGT TGPSVGGKTG ATSSEATSSE GMSGVTGQSL GSTAGSDSEI
1860 1870 1880 1890 1900
TAKTSFTGSS PPGKLTRPSP GSPGHFSGGT TEWGNVATTG AAGENTSGAL
1910 1920 1930 1940 1950
GSTEGSVEAT TSAGSGNTAG TSGTGDTGPG NTAVSGTPVV SPGATPGAPG
1960 1970 1980 1990 2000
SSTPGEADIG NTSFGKSGTP TVSAASTTSS PVSKHTDAAS ATAVTISGSK
2010 2020 2030 2040 2050
PGTPGTPGGA TSGGKITSGW SSSGTSTGAS NTPGATGSST GQTDTSGPSA
2060 2070 2080 2090 2100
KVTGNYGQSS EIPGTIKSSS DVSGTMGQSD TTSGPSVAVT RTSEQSSGVT
2110 2120 2130 2140 2150
VASEPSVGVS GTTGPLAEIS GTTRPLVSGL RTTGSSAEGS GTTGPSSRES
2160 2170 2180 2190 2200
VTTRPLAEGS GTSGQSVTGS RATGLSATEL GTTVSFTGGL GTSRSSARET
2210 2220 2230 2240 2250
RTTGPSADGS GTTGPSVVRS GTTRLSVGVT RATESSPGVT GTTTPSAEES
2260 2270 2280 2290 2300
RTTGPSVLVT GTTGQSGQGS GTTGKSFIES GPSVVGSGTT GPTSAGLGTT
2310 2320 2330 2340 2350
APSTRRSSTT KPSVGRTGTT GQSGAESGTT EPSARVAGVT GTSAEVSGRI
2360 2370 2380 2390 2400
EPSATESSTS RPLGETTGTT IPSMEGSEAT GPSVIGSETT RLSVIGSGTT
2410 2420 2430 2440 2450
GTSSGGSGAT RSSGGGMGTT GQSTARSETT GPLFGLTGTF GQSATVTGTS
2460 2470 2480 2490 2500
SNSAGVTTPE KSPGVAMTTG LLVEGSATTQ PRILESETTE SSAGVIVTSG
2510 2520 2530 2540 2550
QSARVTGATG PSAGETGTTE PSTEGSVAAV LFVIGSETTR PLDIGSGTTG
2560 2570 2580 2590 2600
TLSGGSSTTR SSDGTTGTTR KSTARSETTG LSGLTGTSGQ LAGVTGTSSK
2610 2620 2630 2640 2650
SAGVTVTSEK SAGVAVITGS FVERPVTTGP PLLESETTRP SGGVTVTSGQ
2660 2670 2680 2690 2700
SARVTETVGA SAGVTGTTGP STEGSGATGP SVVGSGTTRP LAGESGTTES
2710 2720 2730 2740 2750
SAGVTGTRPS SSRESATTGP SDEGSGTTGL SAGVTVTSGQ SVRKTGTTGA
2760 2770 2780 2790 2800
PAGVTETTRP SVVKSGTTGP SVIGTRTTGT SSGGSGATRS SGGETETTGQ
2810 2820 2830 2840 2850
SAVKSGTTES FTRLTRTSGQ SAGMTGTSAQ SAGVALTSPF VEGLVTTGSS
2860 2870 2880 2890 2900
TVGLETTRPS AVGSGKTGPP VVKAQTTGPS AGVTVTSGQS ARMTGASGPS
2910 2920 2930 2940 2950
VGVTGTTGPA SKGLGTIRPS VVGLETTELS AEGSGTTGPP IVGETTVPSA
2960 2970 2980 2990 3000
GVTVTSGYSD RVTGATEPLA GVTGTIKPSV AGSVTTGPSV TGVETTAKTT
3010 3020 3030 3040 3050
SGGLSTTISS VGGTGTTGQS PERSGTTGPF TGLTGTSAQS AGVTMTSIQS
3060 3070 3080 3090 3100
AGVLVTTGLN VDGLGTTGKA LIGSGTTGLS AEATGTIGPS TEGLEKTGPS
3110 3120 3130 3140 3150
ITGSGTTRPL VTESWTAGTS SGGHSTTSPS VRGTETTGQS AAESVTTGPV
3160 3170 3180 3190 3200
TGYTETSGPS AGVTVTPRQS PTVTQTTGSS AAVSGTTVQS LTVSGTTRPS
3210 3220 3230 3240 3250
SGQTEITGSS VKESGTTESS AVRSGTTGPT AGVTGTNGPS SAGVTGITGS
3260 3270 3280 3290 3300
SPGVTGTTGS SPGVTGTTGS SARSGTSIPS VGKTGTTRTS VEESRTTRPS
3310 3320 3330 3340 3350
AGITGTNGLS AEVTGTTGPL AGVTGTTGPS AGVTRTTGLS AGETGTTGLS
3360 3370 3380 3390 3400
PGVTRTTRSS AGLTGKTGLS AGVTGKTGLS AEVTGTTRLS AGVTGTTGPS
3410 3420 3430 3440 3450
PGVTGTTGTP AGVTGTTELS AGVTGKTGLS SEVTETTGLS YGVKRTIGLS
3460 3470 3480 3490 3500
AGSTGTSGQS AGVAGTTTLS AEVTGTTRPS AGVTGTTGLS AEVTEITGIS
3510 3520 3530 3540 3550
AVVTGTTGPS AGVTETTGSS AGVAGTTRLS AGVTGITGLS AGVTGTTGLS
3560 3570 3580 3590 3600
TEVTGTTGPS AGATGTTGLS VGVTGITGLS DVVTETTGSS ARSGTGIPSV
3610 3620 3630 3640 3650
GETRTTSTSV EESRTTRPSA GIMGTNGLPA EVTGTTEPLA GGTGTTGILA
3660 3670 3680 3690 3700
GVTGTTGLSA GETGKIGSSA GVTGKTGSSA RVTGKTGPSA EVTGKTGLSA
3710 3720 3730 3740 3750
GVTGTTGLSP GVTGTSGLSA EVTGTTGPSA EATGLPGVSA GVTGTTGSLA
3760 3770 3780 3790 3800
GGTGTIGLSA GVTGTTGSSA GVTGTTGLSA GVTGIAGLSA GVTGITGPSA
3810 3820 3830 3840 3850
GVTGTTTVSA GVTGTTGLSA EATEITGLSA GVTGTTGLSA GVTETIRLSA
3860 3870 3880 3890 3900
GVTGTIRSSA GVTGITGLSA GVTGTTGPSA GVTGSTGLLA GVTETTGQSA
3910 3920 3930 3940 3950
KVTGTTGQSV GVTGTTRSSG GVTGITGLSA GVTGTNGLSA VTGMTGLSAE
3960 3970 3980 3990 4000
VTGTTGLSVG VTGIAGLSAG VTGITGPSAG ITGTTTISAG VTGTSGLSAE
4010 4020 4030 4040 4050
ATGITGLSAG VTGKTGLSAG VTETIGLSAE ATGTIGSSPG VTGTTGSSTG
4060 4070 4080 4090 4100
VTGITGLSAG VTGTTGLSTE VTGTTGPSAG VTRTTGLSAG VTGITGLSAI
4110 4120 4130 4140 4150
VTETTGSSAR SGTSIPSVGE TGTTRTSVEE SRTTRPSAGI TGTNGLSAEV
4160 4170 4180 4190 4200
TGTIGPLAGG TGTTGLSAGV TGTVGSSAVV TGTTGLSAGV TGTTGPSAEE
4210 4220 4230 4240 4250
TGATGPSAEV TETTGPSAGV TGTGRLSAEV TGTTGPSAEV TGLPGESAEV
4260 4270 4280 4290 4300
TGTIGSPAGV TGTTQLSAVV TGITGLSAEV TGTTGLSAGV TGITGLSAEV
4310 4320 4330 4340 4350
TRTTGLSAGV TGTIGLSAGV TGTTRPSAGV TGTTGQSAEV TGTTEPSAGL
4360 4370 4380 4390 4400
TETTGSSTGV TGATGPLAGV TGTTGISTEV TGTTGPSARV TGTTVLSAGV
4410 4420 4430 4440 4450
TGITGLSAIV TETTGSSARS GTSTPSVGET GTTRTSVEES RATRPSAGIT
4460 4470 4480 4490 4500
GTNGQSAEVT WITGPLAGVT GTTGISAGVT GTTGLSAGVT GTIGSSAVVT
4510 4520 4530 4540 4550
GINGLSAGVT GTTGPSAEET GATGPSAEVT GTTGPSAEET GATGPSAEVT
4560 4570 4580 4590 4600
GTTGPSGGVT GTNGLSAEVT GTTGPSAEVT GLPGVSAGVT GTIGSPAAVT
4610 4620 4630 4640 4650
GTIRPSAVVT GITGLSAEVT GTTGLSAWVT GIAGLSAGVT ETIGSSAGVT
4660 4670 4680 4690 4700
GTNGLSAEAT GTTGPSAGVT GTTGLSAGVT GTAGLSARVT ESTGLSAGVT
4710 4720 4730 4740 4750
GTTGLSAGVT GTTGPSAGIT GTNGLSAEVT GTTGPLAGVT GTIGLSAGVT
4760 4770 4780 4790 4800
GIAGLSAGVT ESTGLSAGVT GTIRSSAVVT GINGLSAGVT GTTGPSAEET
4810 4820 4830 4840 4850
GATGPSAEVT GTTGPSGGVT GTSGISAEVT GTTGPSAEVT GLPGVSAGVT
4860 4870 4880 4890 4900
GTIGSPAAVT GTTRPSAVVT GISGLSAEVT GTTGLSAGVT ETIGSSAGVT
4910 4920 4930 4940 4950
GTNGLSAEAT ETTGPSAGVT GTTGLSAGVT GTTGPSAGIA GTNGLSAGVT
4960 4970 4980 4990 5000
GTTGLSARVT ESTGLSAGVT GTIGSSAVVT ETTRLSSGVT GTIGPSAEET
5010 5020 5030 5040 5050
GATGLSAEVT GTTGSLAEVT GTTGLSAGVT GTIGSSAVVT GTTGLSAGIT
5060 5070 5080 5090 5100
GTNGLSAEVT GTAGPLAGVT GTTGLSAGVT GTTGLSAGVT ETTGQSAGVT
5110 5120 5130 5140 5150
ESTGLSPGVT GTIGSSAVVT GIKGLSAGVT GTTGPSAEET GATGPSAEVT
5160 5170 5180 5190 5200
GTTGPSGGVT GTSVLSVEVT GTTGPSAEVT GLPGVSAGLT GTIGSPAAVR
5210 5220 5230 5240 5250
GTTWPSAVVT GISGLSGEVT GTTGLSAGVT GIGGLSAGVT GTIGSSAGVT
5260 5270 5280 5290 5300
GTNALSAEAT GTTGPSAGVT GTTGLSAGVT GTTGLSAGVT GTIRSSAVVT
5310 5320 5330 5340 5350
ETTGLSAGVT GTTGPSAGIA GTNGLSAEVT GTTGLSAGMT GTTGLSARVT
5360 5370 5380 5390 5400
ESTGLSAGVT GTIGSSAVVT ETTRLSAGVT GTIGPSAEET GATGLSAEVT
5410 5420 5430 5440 5450
RTTGSLAGVT GTTGPSAVVT GKTELSAEVT GTTELSAEVT EKTGPSAEVT
5460 5470 5480 5490 5500
GKTGLSAGVM ETTGPSAEVT GTTGSSAGVT GTTGPSAGVT GTTGPSAEAT
5510 5520 5530 5540 5550
GLPGVSAGVT GTIGSPAGVT GTARLSAVVT GISGLSAEVT GTTGLSTGVT
5560 5570 5580 5590 5600
GIAGHSAAVT GITRPSAGVT GTTTVSAGVT GTIGLSAEAT GITLPSAGVT
5610 5620 5630 5640 5650
ETTGLSAGVT ETIGLSAGVT GTIGSSAGVT EITGLSAGVT GTTGPSAGVT
5660 5670 5680 5690 5700
GSTVLSAGVT ATTGQSVGVT GTTGPSAGVT GTTGLSAGVT GIAGLSAGVT
5710 5720 5730 5740 5750
GITGPSAGVT GTTTVSAGVT GTTGLSAEAT EITGLSAGVT GTTGLSAGVT
5760 5770 5780 5790 5800
GIAGLSAGVT ETIGSSAGVT GTNGLSAEAT GKTGPSAGVT GTTGLSAGVT
5810 5820 5830 5840 5850
GTTGLSAGVT ETIGLSAGVT GTIGSSAGVK GTTGQSAEVT GATGQSVGVT
5860 5870 5880 5890 5900
GTTRSSGGVT GITGLSAGLR GTTVSSAKAG TSIPLTGKTG TTRTSVEEST
5910 5920 5930 5940 5950
TTGPSAGITG TNGLSAEMTG TNELSAGVTG TIGSSAGVTG TTGLSVEATV
5960 5970 5980 5990 6000
TTGLSAGVTG TTVPLAGVTW TPGPSAGVTG IAALSAGVTG KSGLSAGVTG
6010 6020 6030 6040 6050
KTGLSAGVTG TTGPSAEATG KTGLSAGVTG ITGPFAEVTG TTGLSAGVIG
6060 6070 6080 6090 6100
TTGSSAEVTG ITGLSAGVTG KTRSSAGVTG TTGLSAKSGT SIPSAGKTGT
6110 6120 6130 6140 6150
TKTSVEESRT TRPSAGITAT TGVPAATSPG AEGESIASTS VATGAIPRST
6160 6170 6180 6190 6200
IAPGSTTTGT TGVTTGTTLA PRSFNIGTSG GISGKTLKPG SYVSEATTAT
6210 6220 6230 6240 6250
GTPGAGPSGG TTISSPEVST ISEVSNTGIT GVGSETSIET GISNTATTGV
6260 6270 6280 6290 6300
APGTTLAPGS SSTEATTSIG GSASTRGGIA TEATGSTRGV RTTGSEAPEG
6310 6320 6330 6340 6350
TSGEFSGTTI SSGGFHTEAT TLTGGRGSIG TESRAESTTS LPQSAKTRGG
6360 6370 6380 6390 6400
ILTEATSSTG RIRATGSEAP GGTSRKFSGT TISSGGSHTE ATTLAGGRDS
6410 6420 6430 6440 6450
TESEFRTATI GVVPATTVAP GSSKTEATTF LGVSGTTSVG RATGATTSIA
6460 6470 6480 6490 6500
GSDTSQAEHP GGTSGEFPGT TITSGDSHTE ATALTGSRGS IGTESTVETT
6510 6520 6530 6540 6550
TYIGESGTTR GGLATATTGA FSGKTLEPGN DNTEATGSTG GIRATRTEAP
6560 6570 6580 6590 6600
GGTSGEFPGT TFTSGGSHTE ATTFTGGKGS TGTESRAATT RAAPGTTLVP
6610 6620 6630 6640 6650
GSSNTGATAS PGGSATTRGR ITTATTGAFS GKTLESENDN TEATSSTRGV
6660 6670 6680 6690 6700
RTTRSEAPGG TSGEFPGTRI TSGGSYTATT RAAPGTTLAP GSSNTGATAS
6710 6720 6730 6740 6750
LGGSAMTRGR ITTATTGAFS GKTLEPGNNN TEATSSTRGV RTTRSEAPGE
6760 6770 6780 6790 6800
ATTLTGDRSS TGSESRTATT GVAPGTTVAP GSSKTEATTF LGVSGTTNIG
6810 6820 6830 6840 6850
RATGATTSIV GSDTSQAERP GGTTVVSPGA SSTSQSSRPG TSVTPDSSAS
6860 6870 6880 6890 6900
ESETVTTKEF SGTTAISRTS HTGTPAASGG QATGSLTATT GVAPGTTVAP
6910 6920 6930 6940 6950
GSSNTEATTS VGERETTKAE IITGDTGELS GTTIISENST TAGITAATGK
6960 6970 6980 6990 7000
QAGTSEVAPS TTVAPGSFST AATTSPGASG TTGVTTTTKT TTSLGGSGTT
7010 7020 7030 7040 7050
GAEIKSATTG APGSRTGTAG VPSATTVSPG SSNSEATTSV GESGKTGAET
7060 7070 7080 7090 7100
ITEATTSTEG TGTSGTGFKT GTSEVAPATT VAPGSFSTAA TTSPGASGMT
7110 7120 7130 7140 7150
GVTTTTKTTT SLGGSGTTGA KIKLVGTTTT APESRTAGVP SGTRVTPGSS
7160 7170 7180 7190 7200
NSEATTSVEE SRITRAEVIT EATTFSGGSG ATRAGLPRGT TGEFSGTNFI
7210 7220 7230 7240 7250
SGSSNTEATT STEGTGTSGT GFKIAGITSA PGKQAGTSGV SLATTVAPGS
7260 7270 7280 7290 7300
FSTATTSSGA SGITRAGPTS ETTTSLGGSG TTGAEIKSAA VPSGTTVAPG
7310 7320 7330 7340 7350
SSNSEATTSV GENGKTRGEI ITDTTEGTSG KVLEPGSAHT EATTFPGGSG
7360 7370 7380 7390 7400
TTRAGPPGGT TGELSRMTII PGSSNTEATT STKGTGTSGT GFKTGTSWVA
7410 7420 7430 7440 7450
PGTTVSPGSF STATISPGAS RTTGAAPAAE TTTSLEGGGT TGAEIKSGAT
7460 7470 7480 7490 7500
SGVPGSKTGT AGVPSATTIA PGSSNSEATT SLGESGKTRV ETITGTTEGK
7510 7520 7530 7540 7550
TLAAGSAHTE ATTFSGGSGS TRAGPLGGAS GTSGGYVPGR ETEPTTSIEE
7560 7570 7580 7590 7600
TGTSRTIFKT VGITSAPGRQ AGTSVVAPST TVAPGSFSTA ATTSPGASGM
7610 7620 7630 7640 7650
TGVRTTSKTT TSLGGTGTTR TEIKSGATTG APGIKTDIMG ESSRTTILSG
7660 7670 7680 7690 7700
SSNTEATNSI EETGTSGTGF KTAGITAAPG KQAGTSGVAP GTTVAPGSFS
7710 7720 7730 7740 7750
TAATTSPGAS GVTGTGPTAE TTTFLGGSST TGAEIKSGAT TGAPGSKTGT
7760 7770 7780 7790 7800
AKVLSGTTVA SGSSNSEATT FSGITEAVTV PSKNGSMTTA LGSQLSSSQT
7810 7820 7830 7840 7850
VIPGSSGTIS HTTVAPGSSV TGTTTGASDD QVTGSKTGTT GVALSTTVAP
7860 7870 7880 7890 7900
GSSSTEATTS TGVHRTTVVG QKTGATTRGS AKQGTRSTIE ATTSFRGTGT
7910 7920 7930 7940 7950
TGSGMNTGTT GVVSGNTISP SSFNTEATSG TSERPNPGSE IGTTGIVSGT
7960 7970 7980 7990 8000
TVAPGSSNTE ATTSLGNGGT TEAGSKIVTT GITTGTTIVP GSFNTKATTS
8010 8020 8030 8040 8050
TDVGVATGVG MATGITNIIS GRSQPTGSKT GYTVTGSGTT ALPGGFRTGN
8060 8070 8080 8090 8100
TPGSTGVTSS QEGTTVVSSG ITGIPETSIS GPSKEASDKT TAPGPPTTVT
8110 8120 8130 8140 8150
ASTGVKETSE TGVQTGSTLV TAGVPTRPQV SQPETTVVAT REVETENKTE
8160 8170 8180 8190 8200
CLASLPPAPV CHGPLGEEKS PGDIWTANCH RGTCTDAKTI DCKPEECPSP
8210 8220 8230 8240 8250
PTCKTGEKLV KFQSNDTCCE IGYCEPRTCL FNNTDYEIGA SFDDPSNPCV
8260 8270 8280 8290 8300
SYSCKDTGFA AVVQDCPKQT WCAEANRIYD SKKCCYTCKN NCRSSLVNVT
8310 8320 8330 8340 8350
VIYSGCKKRV QMAKCTGECE KTAKYNYDIL LLEHSCLCCR EENYELRDIV
8360 8370 8380
LDCPDGSTIP YQYKHITTCS CLDICQLYTT FMYS
Length:8,384
Mass (Da):805,253
Last modified:June 8, 2016 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iD4FFE16047237C93
GO
Isoform 2 (identifier: Q7Z5P9-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     8049-8066: GNTPGSTGVTSSQEGTTV → DSPSFPLFLICSYRGHNF
     8067-8384: Missing.

Note: No experimental confirmation available.
Show »
Length:8,066
Mass (Da):771,155
Checksum:i51F5C2D93A728DC9
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A2R8Y6K8A0A2R8Y6K8_HUMAN
Mucin-19
MUC19
352Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAC04041 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti8091T → S in AAP41817 (PubMed:12882755).Curated1
Sequence conflicti8327Y → H in AAP41817 (PubMed:12882755).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_056617717G → E. Corresponds to variant dbSNP:rs7955308Ensembl.1
Natural variantiVAR_056618783T → K. Corresponds to variant dbSNP:rs11564170Ensembl.1
Natural variantiVAR_056619790V → I. Corresponds to variant dbSNP:rs7958987Ensembl.1
Natural variantiVAR_056620791R → L. Corresponds to variant dbSNP:rs17467284Ensembl.1
Natural variantiVAR_056621803D → H. Corresponds to variant dbSNP:rs11564245Ensembl.1
Natural variantiVAR_056622843V → I. Corresponds to variant dbSNP:rs10506156Ensembl.1
Natural variantiVAR_056623869V → I. Corresponds to variant dbSNP:rs28365246Ensembl.1
Natural variantiVAR_056624883V → I. Corresponds to variant dbSNP:rs11564125Ensembl.1
Natural variantiVAR_0566251010L → F. Corresponds to variant dbSNP:rs12317988Ensembl.1
Natural variantiVAR_0566261151I → T. Corresponds to variant dbSNP:rs11176635Ensembl.1
Natural variantiVAR_0566271226S → F. Corresponds to variant dbSNP:rs4768261Ensembl.1
Natural variantiVAR_0566281278I → M. Corresponds to variant dbSNP:rs7966110Ensembl.1
Natural variantiVAR_0566291296G → S. Corresponds to variant dbSNP:rs4768264Ensembl.1
Natural variantiVAR_0566301315R → H. Corresponds to variant dbSNP:rs7312154Ensembl.1
Natural variantiVAR_0566311327G → W. Corresponds to variant dbSNP:rs12369002Ensembl.1
Natural variantiVAR_0566321367A → T. Corresponds to variant dbSNP:rs11564141Ensembl.1
Natural variantiVAR_0566331411C → Y. Corresponds to variant dbSNP:rs11564109Ensembl.1
Natural variantiVAR_0566341451A → T. Corresponds to variant dbSNP:rs11176666Ensembl.1
Natural variantiVAR_0566351493A → V. Corresponds to variant dbSNP:rs10784621Ensembl.1
Natural variantiVAR_0566361621N → S. Corresponds to variant dbSNP:rs17128169Ensembl.1
Natural variantiVAR_0566371688T → A. Corresponds to variant dbSNP:rs17128233Ensembl.1
Natural variantiVAR_0566381762E → A. Corresponds to variant dbSNP:rs2933353Ensembl.1
Natural variantiVAR_0566391770S → R. Corresponds to variant dbSNP:rs7956459Ensembl.1
Natural variantiVAR_0566402029A → S. Corresponds to variant dbSNP:rs1492333Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0345218049 – 8066GNTPG…EGTTV → DSPSFPLFLICSYRGHNF in isoform 2. 1 PublicationAdd BLAST18
Alternative sequenceiVSP_0345228067 – 8384Missing in isoform 2. 1 PublicationAdd BLAST318

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
HM801842 mRNA Translation: AEM63682.1
AC024935 Genomic DNA No translation available.
AC074030 Genomic DNA No translation available.
AC107023 Genomic DNA No translation available.
AY236870 mRNA Translation: AAP41817.1
AK093065 mRNA Translation: BAC04041.1 Different initiation.

NCBI Reference Sequences

More...
RefSeqi
NP_775871.2, NM_173600.2 [Q7Z5P9-1]

Genome annotation databases

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
283463

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:283463

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

<p>This subsection of the <a href="http://www.uniprot.org/manual/cross_references_section">Cross-references</a> section provides links to various web resources that are relevant for a specific protein.<p><a href='/help/web_resource' target='_top'>More...</a></p>Web resourcesi

Mucin database

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HM801842 mRNA Translation: AEM63682.1
AC024935 Genomic DNA No translation available.
AC074030 Genomic DNA No translation available.
AC107023 Genomic DNA No translation available.
AY236870 mRNA Translation: AAP41817.1
AK093065 mRNA Translation: BAC04041.1 Different initiation.
RefSeqiNP_775871.2, NM_173600.2 [Q7Z5P9-1]

3D structure databases

SMRiQ7Z5P9
ModBaseiSearch...
MobiDBiSearch...

PTM databases

iPTMnetiQ7Z5P9
PhosphoSitePlusiQ7Z5P9

Polymorphism and mutation databases

BioMutaiHGNC:14362

Proteomic databases

EPDiQ7Z5P9
jPOSTiQ7Z5P9
PaxDbiQ7Z5P9
PeptideAtlasiQ7Z5P9
PRIDEiQ7Z5P9
ProteomicsDBi69340
69341 [Q7Z5P9-2]

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi283463
KEGGihsa:283463

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
283463
DisGeNETi283463

GeneCards: human genes, protein and diseases

More...
GeneCardsi
MUC19

H-Invitational Database, human transcriptome db

More...
H-InvDBi
HIX0210549
HGNCiHGNC:14362 MUC19
MIMi612170 gene
neXtProtiNX_Q7Z5P9

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410IR85 Eukaryota
ENOG410ZXRK LUCA
InParanoidiQ7Z5P9
KOiK22020
OrthoDBi12226at2759

Enzyme and pathway databases

ReactomeiR-HSA-5083625 Defective GALNT3 causes familial hyperphosphatemic tumoral calcinosis (HFTC)
R-HSA-5083632 Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)
R-HSA-5083636 Defective GALNT12 causes colorectal cancer 1 (CRCS1)
R-HSA-5621480 Dectin-2 family
R-HSA-913709 O-linked glycosylation of mucins
R-HSA-977068 Termination of O-glycan biosynthesis

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
MUC19 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
283463

Protein Ontology

More...
PROi
PR:Q7Z5P9

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Family and domain databases

InterProiView protein in InterPro
IPR006207 Cys_knot_C
IPR036084 Ser_inhib-like_sf
IPR002919 TIL_dom
IPR014853 Unchr_dom_Cys-rich
IPR001007 VWF_dom
IPR001846 VWF_type-D
PfamiView protein in Pfam
PF08742 C8, 2 hits
PF01826 TIL, 1 hit
PF00094 VWD, 3 hits
SMARTiView protein in SMART
SM00832 C8, 2 hits
SM00041 CT, 1 hit
SM00214 VWC, 3 hits
SM00215 VWC_out, 2 hits
SM00216 VWD, 3 hits
SUPFAMiSSF57567 SSF57567, 3 hits
PROSITEiView protein in PROSITE
PS01185 CTCK_1, 1 hit
PS01225 CTCK_2, 1 hit
PS50184 VWFC_2, 1 hit
PS51233 VWFD, 3 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiMUC19_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q7Z5P9
Secondary accession number(s): G3CIG0, Q8NA85
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 1, 2008
Last sequence update: June 8, 2016
Last modified: May 8, 2019
This is version 99 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 12
    Human chromosome 12: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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