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Entry version 111 (12 Aug 2020)
Sequence version 1 (01 Oct 2003)
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Protein

Chemokine-like protein TAFA-3

Gene

TAFA3

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Plays a role in the regulation of microglia polarization.By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
Q7Z5A8

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Chemokine-like protein TAFA-3Curated
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:TAFA3Imported
Synonyms:FAM19A3Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000184599.13

Human Gene Nomenclature Database

More...
HGNCi
HGNC:21590, TAFA3

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
617497, gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q7Z5A8

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Secreted

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
284467

Open Targets

More...
OpenTargetsi
ENSG00000184599

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134899352

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q7Z5A8, Tdark

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
FAM19A3

Domain mapping of disease mutations (DMDM)

More...
DMDMi
74750123

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 30Sequence analysisAdd BLAST30
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000004272631 – 133Chemokine-like protein TAFA-3Add BLAST103

Proteomic databases

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q7Z5A8

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q7Z5A8

PeptideAtlas

More...
PeptideAtlasi
Q7Z5A8

PRoteomics IDEntifications database

More...
PRIDEi
Q7Z5A8

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
69278 [Q7Z5A8-1]
69279 [Q7Z5A8-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q7Z5A8

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q7Z5A8

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Brain-specific.2 Publications

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000184599, Expressed in adrenal gland and 69 other tissues

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000184599, Group enriched (adrenal gland, brain, testis)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
129885, 79 interactors

Protein interaction database and analysis system

More...
IntActi
Q7Z5A8, 74 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000358644

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q7Z5A8, protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the TAFA family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502SVHN, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000155644

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_126078_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q7Z5A8

Identification of Orthologs from Complete Genome Data

More...
OMAi
RWSPACP

Database of Orthologous Groups

More...
OrthoDBi
1403365at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q7Z5A8

TreeFam database of animal gene trees

More...
TreeFami
TF331749

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR020350, Chemokine-like_TAFA

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF12020, TAFA, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform 1 (identifier: Q7Z5A8-1) [UniParc]FASTAAdd to basket
Also known as: TAFA3

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MSERVERNWS TGGWLLALCL AWLWTHLTLA ALQPPTATVL VQQGTCEVIA
60 70 80 90 100
AHRCCNRNRI EERSQTVKCS CFSGQVAGTT RAKPSCVDAS IVLQRWWCQM
110 120 130
EPCLPGEECK VLPDLSGWSC SSGHKVKTTK VTR
Length:133
Mass (Da):14,776
Last modified:October 1, 2003 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iC074C703817D008D
GO
Isoform 2 (identifier: Q7Z5A8-2) [UniParc]FASTAAdd to basket
Also known as: TAFA3.2

The sequence of this isoform differs from the canonical sequence as follows:
     89-133: ASIVLQRWWC...HKVKTTKVTR → DLLLAAHCAR...GSRPGQERLD

Show »
Length:169
Mass (Da):18,549
Checksum:iA7726BC3E9D48496
GO

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_01606789 – 133ASIVL…TKVTR → DLLLAAHCARRDPRAALRLL LPQPPSSCRDGGVRWSPACR GRSVRCSRTCRDGAAAVDTK SKPPRSHDSSWGSRPGQERL D in isoform 2. 2 PublicationsAdd BLAST45

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AY325116 mRNA Translation: AAP92408.1
AY325119 mRNA Translation: AAP92411.1
AL603832 Genomic DNA No translation available.
CH471122 Genomic DNA Translation: EAW56548.1
CH471122 Genomic DNA Translation: EAW56549.1
BC112268 mRNA Translation: AAI12269.1
BC117479 mRNA Translation: AAI17480.1
BC144043 mRNA Translation: AAI44044.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS30806.1 [Q7Z5A8-2]
CCDS856.1 [Q7Z5A8-1]

NCBI Reference Sequences

More...
RefSeqi
NP_001004440.1, NM_001004440.1 [Q7Z5A8-2]
NP_877436.1, NM_182759.2 [Q7Z5A8-1]
XP_005270823.1, XM_005270766.3 [Q7Z5A8-1]
XP_006710645.1, XM_006710582.3 [Q7Z5A8-2]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000361886; ENSP00000355042; ENSG00000184599 [Q7Z5A8-1]
ENST00000369630; ENSP00000358644; ENSG00000184599 [Q7Z5A8-2]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
284467

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:284467

UCSC genome browser

More...
UCSCi
uc001ecu.4, human [Q7Z5A8-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY325116 mRNA Translation: AAP92408.1
AY325119 mRNA Translation: AAP92411.1
AL603832 Genomic DNA No translation available.
CH471122 Genomic DNA Translation: EAW56548.1
CH471122 Genomic DNA Translation: EAW56549.1
BC112268 mRNA Translation: AAI12269.1
BC117479 mRNA Translation: AAI17480.1
BC144043 mRNA Translation: AAI44044.1
CCDSiCCDS30806.1 [Q7Z5A8-2]
CCDS856.1 [Q7Z5A8-1]
RefSeqiNP_001004440.1, NM_001004440.1 [Q7Z5A8-2]
NP_877436.1, NM_182759.2 [Q7Z5A8-1]
XP_005270823.1, XM_005270766.3 [Q7Z5A8-1]
XP_006710645.1, XM_006710582.3 [Q7Z5A8-2]

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi129885, 79 interactors
IntActiQ7Z5A8, 74 interactors
STRINGi9606.ENSP00000358644

PTM databases

iPTMnetiQ7Z5A8
PhosphoSitePlusiQ7Z5A8

Polymorphism and mutation databases

BioMutaiFAM19A3
DMDMi74750123

Proteomic databases

MassIVEiQ7Z5A8
PaxDbiQ7Z5A8
PeptideAtlasiQ7Z5A8
PRIDEiQ7Z5A8
ProteomicsDBi69278 [Q7Z5A8-1]
69279 [Q7Z5A8-2]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
33837, 101 antibodies

The DNASU plasmid repository

More...
DNASUi
284467

Genome annotation databases

EnsembliENST00000361886; ENSP00000355042; ENSG00000184599 [Q7Z5A8-1]
ENST00000369630; ENSP00000358644; ENSG00000184599 [Q7Z5A8-2]
GeneIDi284467
KEGGihsa:284467
UCSCiuc001ecu.4, human [Q7Z5A8-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
284467
DisGeNETi284467
EuPathDBiHostDB:ENSG00000184599.13

GeneCards: human genes, protein and diseases

More...
GeneCardsi
TAFA3
HGNCiHGNC:21590, TAFA3
HPAiENSG00000184599, Group enriched (adrenal gland, brain, testis)
MIMi617497, gene
neXtProtiNX_Q7Z5A8
OpenTargetsiENSG00000184599
PharmGKBiPA134899352

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG502SVHN, Eukaryota
GeneTreeiENSGT00940000155644
HOGENOMiCLU_126078_0_0_1
InParanoidiQ7Z5A8
OMAiRWSPACP
OrthoDBi1403365at2759
PhylomeDBiQ7Z5A8
TreeFamiTF331749

Enzyme and pathway databases

PathwayCommonsiQ7Z5A8

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
284467, 3 hits in 876 CRISPR screens

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
284467
PharosiQ7Z5A8, Tdark

Protein Ontology

More...
PROi
PR:Q7Z5A8
RNActiQ7Z5A8, protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000184599, Expressed in adrenal gland and 69 other tissues

Family and domain databases

InterProiView protein in InterPro
IPR020350, Chemokine-like_TAFA
PfamiView protein in Pfam
PF12020, TAFA, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiTAFA3_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q7Z5A8
Secondary accession number(s): B7ZLU0, Q2M1P9, Q7Z5A6
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 8, 2005
Last sequence update: October 1, 2003
Last modified: August 12, 2020
This is version 111 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families
  3. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
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