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Entry version 125 (07 Apr 2021)
Sequence version 3 (03 Mar 2009)
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Protein

Zinc finger protein 804A

Gene

ZNF804A

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri57 – 81C2H2-typeAdd BLAST25

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

LigandMetal-binding, Zinc

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
Q7Z570

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Zinc finger protein 804A
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ZNF804A
Synonyms:C2orf10
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:21711, ZNF804A

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
612282, gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q7Z570

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
HostDB:ENSG00000170396.7

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
91752

Open Targets

More...
OpenTargetsi
ENSG00000170396

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA162410599

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q7Z570, Tbio

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
ZNF804A

Domain mapping of disease mutations (DMDM)

More...
DMDMi
224471869

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002325181 – 1209Zinc finger protein 804AAdd BLAST1209

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q7Z570

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q7Z570

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q7Z570

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q7Z570

PeptideAtlas

More...
PeptideAtlasi
Q7Z570

PRoteomics IDEntifications database

More...
PRIDEi
Q7Z570

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
69261

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q7Z570

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q7Z570

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000170396, Expressed in frontal cortex and 127 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q7Z570, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q7Z570, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000170396, Group enriched (brain, lymphoid tissue)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
124875, 5 interactors

Protein interaction database and analysis system

More...
IntActi
Q7Z570, 4 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000303252

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q7Z570, protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri57 – 81C2H2-typeAdd BLAST25

Keywords - Domaini

Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502QQR4, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000160909

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_276771_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q7Z570

Identification of Orthologs from Complete Genome Data

More...
OMAi
DHRCLVL

Database of Orthologous Groups

More...
OrthoDBi
332880at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q7Z570

TreeFam database of animal gene trees

More...
TreeFami
TF332138

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR022755, Znf_C2H2_jaz
IPR036236, Znf_C2H2_sf
IPR013087, Znf_C2H2_type

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF12171, zf-C2H2_jaz, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF57667, SSF57667, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00028, ZINC_FINGER_C2H2_1, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q7Z570-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MECYYIVISS THLSNGHFRN IKGVFRGPLS KNGNKTLDYA EKENTIAKAL
60 70 80 90 100
EDLKANFYCE LCDKQYYKHQ EFDNHINSYD HAHKQRLKEL KQREFARNVA
110 120 130 140 150
SKSRKDERKQ EKALQRLHKL AELRKETVCA PGSGPMFKST TVTVRENCNE
160 170 180 190 200
ISQRVVVDSV NNQQDFKYTL IHSEENTKDA TTVAEDPESA NNYTAKNNQV
210 220 230 240 250
GDQAQGIHRH KIGFSFAFPK KASVKLESSA AAFSEYSDDA SVGKGFSRKS
260 270 280 290 300
RFVPSACHLQ QSSPTDVLLS SEEKTNSFHP PEAMCRDKET VQTQEIKEVS
310 320 330 340 350
SEKDALLLPS FCKFQLQLSS DADNCQNSVP LADQIPLESV VINEDIPVSG
360 370 380 390 400
NSFELLGNKS TVLDMSNDCI SVQATTEENV KHNEASTTEV ENKNGPETLA
410 420 430 440 450
PSNTEEVNIT IHKKTNFCKR QCEPFVPVLN KHRSTVLQWP SEMLVYTTTK
460 470 480 490 500
PSISYSCNPL CFDFKSTKVN NNLDKNKPDL KDLCSQQKQE DICMGPLSDY
510 520 530 540 550
KDVSTEGLTD YEIGSSKNKC SQVTPLLADD ILSSSCDSGK NENTGQRYKN
560 570 580 590 600
ISCKIRETEK YNFTKSQIKQ DTLDEKYNKI RLKETHEYWF HKSRRKKKRK
610 620 630 640 650
KLCQHHHMEK TKESETRCKM EAENSYTENA GKYLLEPISE KQYLAAEQLL
660 670 680 690 700
DSHQLLDKRP KSESISLSDN EEMCKTWNTE YNTYDTISSK NHCKKNTILL
710 720 730 740 750
NGQSNATMIH SGKHNLTYSR TYCCWKTKMS SCSQDHRSLV LQNDMKHMSQ
760 770 780 790 800
NQAVKRGYNS VMNESERFYR KRRQHSHSYS SDESLNRQNH LPEEFLRPPS
810 820 830 840 850
TSVAPCKPKK KRRRKRGRFH PGFETLELKE NTDYPVKDNS SLNPLDRLIS
860 870 880 890 900
EDKKEKMKPQ EVAKIERNSE QTNQLRNKLS FHPNNLLPSE TNGETEHLEM
910 920 930 940 950
ETTSGELSDV SNDPTTSVCV ASAPTKEAID NTLLEHKERS ENINLNEKQI
960 970 980 990 1000
PFQVPNIERN FRQSQPKSYL CHYELAEALP QGKMNETPTE WLRYNSGILN
1010 1020 1030 1040 1050
TQPPLPFKEA HVSGHTFVTA EQILAPLALP EQALLIPLEN HDKFKNVPCE
1060 1070 1080 1090 1100
VYQHILQPNM LANKVKFTFP PAALPPPSTP LQPLPLQQSL CSTSVTTIHH
1110 1120 1130 1140 1150
TVLQQHAAAA AAAAAAAAAG TFKVLQPHQQ FLSQIPALTR TSLPQLSVGP
1160 1170 1180 1190 1200
VGPRLCPGNQ PTFVAPPQMP IIPASVLHPS HLAFPSLPHA LFPSLLSPHP

TVIPLQPLF
Length:1,209
Mass (Da):136,888
Last modified:March 3, 2009 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i467982636EF1DFC0
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti492I → V in AAI50199 (PubMed:15489334).Curated1
Sequence conflicti545G → S in AAI50199 (PubMed:15489334).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_025943261Q → L1 PublicationCorresponds to variant dbSNP:rs12476147Ensembl.1
Natural variantiVAR_035599324N → S in a colorectal cancer sample; somatic mutation. 1 Publication1
Natural variantiVAR_054133479D → G1 PublicationCorresponds to variant dbSNP:rs35676856Ensembl.1
Natural variantiVAR_025944542E → K1 PublicationCorresponds to variant dbSNP:rs4667001Ensembl.1
Natural variantiVAR_054134600K → R. Corresponds to variant dbSNP:rs35925696Ensembl.1
Natural variantiVAR_025945707T → K. Corresponds to variant dbSNP:rs1366842Ensembl.1
Natural variantiVAR_025946747H → R1 PublicationCorresponds to variant dbSNP:rs12477430Ensembl.1
Natural variantiVAR_0259471081L → V. Corresponds to variant dbSNP:rs3731834Ensembl.1
Natural variantiVAR_0541351152G → R. Corresponds to variant dbSNP:rs12105159Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AY327407 mRNA Translation: AAP92799.1
AC010747 Genomic DNA No translation available.
AC112720 Genomic DNA No translation available.
AC096667 Genomic DNA No translation available.
BC150198 mRNA Translation: AAI50199.1
AK131402 mRNA Translation: BAD18549.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS2291.1

NCBI Reference Sequences

More...
RefSeqi
NP_919226.1, NM_194250.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000302277; ENSP00000303252; ENSG00000170396

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
91752

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:91752

UCSC genome browser

More...
UCSCi
uc002uph.4, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY327407 mRNA Translation: AAP92799.1
AC010747 Genomic DNA No translation available.
AC112720 Genomic DNA No translation available.
AC096667 Genomic DNA No translation available.
BC150198 mRNA Translation: AAI50199.1
AK131402 mRNA Translation: BAD18549.1
CCDSiCCDS2291.1
RefSeqiNP_919226.1, NM_194250.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi124875, 5 interactors
IntActiQ7Z570, 4 interactors
STRINGi9606.ENSP00000303252

PTM databases

iPTMnetiQ7Z570
PhosphoSitePlusiQ7Z570

Genetic variation databases

BioMutaiZNF804A
DMDMi224471869

Proteomic databases

EPDiQ7Z570
jPOSTiQ7Z570
MassIVEiQ7Z570
PaxDbiQ7Z570
PeptideAtlasiQ7Z570
PRIDEiQ7Z570
ProteomicsDBi69261

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
33997, 26 antibodies

Genome annotation databases

EnsembliENST00000302277; ENSP00000303252; ENSG00000170396
GeneIDi91752
KEGGihsa:91752
UCSCiuc002uph.4, human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
91752
DisGeNETi91752

GeneCards: human genes, protein and diseases

More...
GeneCardsi
ZNF804A
HGNCiHGNC:21711, ZNF804A
HPAiENSG00000170396, Group enriched (brain, lymphoid tissue)
MIMi612282, gene
neXtProtiNX_Q7Z570
OpenTargetsiENSG00000170396
PharmGKBiPA162410599
VEuPathDBiHostDB:ENSG00000170396.7

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG502QQR4, Eukaryota
GeneTreeiENSGT00940000160909
HOGENOMiCLU_276771_0_0_1
InParanoidiQ7Z570
OMAiDHRCLVL
OrthoDBi332880at2759
PhylomeDBiQ7Z570
TreeFamiTF332138

Enzyme and pathway databases

PathwayCommonsiQ7Z570

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
91752, 8 hits in 990 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
ZNF804A, human

The Gene Wiki collection of pages on human genes and proteins

More...
GeneWikii
Zinc_finger_protein_804A

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
91752
PharosiQ7Z570, Tbio

Protein Ontology

More...
PROi
PR:Q7Z570
RNActiQ7Z570, protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000170396, Expressed in frontal cortex and 127 other tissues
ExpressionAtlasiQ7Z570, baseline and differential
GenevisibleiQ7Z570, HS

Family and domain databases

InterProiView protein in InterPro
IPR022755, Znf_C2H2_jaz
IPR036236, Znf_C2H2_sf
IPR013087, Znf_C2H2_type
PfamiView protein in Pfam
PF12171, zf-C2H2_jaz, 1 hit
SUPFAMiSSF57667, SSF57667, 1 hit
PROSITEiView protein in PROSITE
PS00028, ZINC_FINGER_C2H2_1, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiZ804A_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q7Z570
Secondary accession number(s): A7E253, Q6ZN26
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 18, 2006
Last sequence update: March 3, 2009
Last modified: April 7, 2021
This is version 125 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 2
    Human chromosome 2: entries, gene names and cross-references to MIM
  2. Human entries with genetic variants
    List of human entries with genetic variants
  3. Human variants curated from literature reports
    Index of human variants curated from literature reports
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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