UniProtKB - Q7Z4U5 (CF201_HUMAN)
Protein
Uncharacterized protein C6orf201
Gene
C6orf201
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Recommended name: Uncharacterized protein C6orf201 |
Gene namesi | Name:C6orf201 |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
EuPathDBi | HostDB:ENSG00000185689.15 |
HGNCi | HGNC:21620, C6orf201 |
neXtProti | NX_Q7Z4U5 |
Pathology & Biotechi
Organism-specific databases
OpenTargetsi | ENSG00000185689 |
PharmGKBi | PA134906041 |
Miscellaneous databases
Pharosi | Q7Z4U5, Tdark |
Polymorphism and mutation databases
BioMutai | C6orf201 |
DMDMi | 327478579 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000297587 | 1 – 140 | Uncharacterized protein C6orf201Add BLAST | 140 |
Proteomic databases
PaxDbi | Q7Z4U5 |
PRIDEi | Q7Z4U5 |
ProteomicsDBi | 69242 [Q7Z4U5-2] 69243 [Q7Z4U5-3] |
PTM databases
PhosphoSitePlusi | Q7Z4U5 |
Expressioni
Gene expression databases
Bgeei | ENSG00000185689, Expressed in sperm and 115 other tissues |
Genevisiblei | Q7Z4U5, HS |
Organism-specific databases
HPAi | ENSG00000185689, Tissue enriched (testis) |
Interactioni
Binary interactionsi
Isoform 2 [Q7Z4U5-3]
With | #Exp. | IntAct |
---|---|---|
EIF3F [O00303] | 3 | EBI-18680706,EBI-711990 |
Protein-protein interaction databases
BioGRIDi | 135654, 3 interactors |
IntActi | Q7Z4U5, 3 interactors |
STRINGi | 9606.ENSP00000420610 |
Miscellaneous databases
RNActi | Q7Z4U5, protein |
Family & Domainsi
Phylogenomic databases
eggNOGi | ENOG502S904, Eukaryota |
GeneTreei | ENSGT00390000008360 |
HOGENOMi | CLU_136293_0_0_1 |
InParanoidi | Q7Z4U5 |
OMAi | GISEPTW |
OrthoDBi | 1234300at2759 |
PhylomeDBi | Q7Z4U5 |
TreeFami | TF341213 |
Family and domain databases
InterProi | View protein in InterPro IPR027827, DUF4523 |
PANTHERi | PTHR35968, PTHR35968, 1 hit |
Pfami | View protein in Pfam PF15023, DUF4523, 1 hit |
s (2)i Sequence
Sequence statusi: Complete.
This entry describes 2 produced by isoformsialternative splicing. AlignAdd to basketIsoform 1 (identifier: Q7Z4U5-2) [UniParc]FASTAAdd to basket
This isoform has been chosen as the sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. canonicali
10 20 30 40 50
MLSNLHELLP NHLMETLYSR KSEEDKKKCE NPELSGLERI LARHQLPKEI
60 70 80 90 100
NLTPKPNRMP PWKRKIINNV TDGWKKCHLL KRNTKEPPMS TIVVRKLIQK
110 120 130 140
NVPRRHSLRN TSRKLRNLPT TAKGTQTGKS QCLLGISEPT
Isoform 2 (identifier: Q7Z4U5-3) [UniParc]FASTAAdd to basket
The sequence of this isoform differs from the canonical sequence as follows:
1-29: MLSNLHELLPNHLMETLYSRKSEEDKKKC → MASGPLGPGARPTRLHPPFPPPAHIKPGAPPG
128-140: GKSQCLLGISEPT → E
Note: May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay.Curated
Show »Natural variant
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Natural variantiVAR_056805 | 20 | R → P2 PublicationsCorresponds to variant dbSNP:rs619483Ensembl. | 1 | |
Natural variantiVAR_056806 | 25 | D → Y. Corresponds to variant dbSNP:rs9503910Ensembl. | 1 | |
Natural variantiVAR_064769 | 117 | N → K2 PublicationsCorresponds to variant dbSNP:rs643232Ensembl. | 1 |
Alternative sequence
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Alternative sequenceiVSP_040789 | 1 – 29 | MLSNL…DKKKC → MASGPLGPGARPTRLHPPFP PPAHIKPGAPPG in isoform 2. 1 PublicationAdd BLAST | 29 | |
Alternative sequenceiVSP_040790 | 128 – 140 | GKSQC…ISEPT → E in isoform 2. 1 PublicationAdd BLAST | 13 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF429972 mRNA Translation: AAP97304.1 AL033383 Genomic DNA No translation available. BC047663 mRNA Translation: AAH47663.1 BC066986 mRNA Translation: AAH66986.1 |
CCDSi | CCDS43419.1 [Q7Z4U5-2] |
RefSeqi | NP_001078870.1, NM_001085401.2 [Q7Z4U5-2] |
Genome annotation databases
Ensembli | ENST00000380175; ENSP00000420610; ENSG00000185689 [Q7Z4U5-2] |
GeneIDi | 404220 |
KEGGi | hsa:404220 |
UCSCi | uc003mwa.5, human [Q7Z4U5-2] |
Keywords - Coding sequence diversityi
Alternative splicing, PolymorphismSimilar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF429972 mRNA Translation: AAP97304.1 AL033383 Genomic DNA No translation available. BC047663 mRNA Translation: AAH47663.1 BC066986 mRNA Translation: AAH66986.1 |
CCDSi | CCDS43419.1 [Q7Z4U5-2] |
RefSeqi | NP_001078870.1, NM_001085401.2 [Q7Z4U5-2] |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
BioGRIDi | 135654, 3 interactors |
IntActi | Q7Z4U5, 3 interactors |
STRINGi | 9606.ENSP00000420610 |
PTM databases
PhosphoSitePlusi | Q7Z4U5 |
Polymorphism and mutation databases
BioMutai | C6orf201 |
DMDMi | 327478579 |
Proteomic databases
PaxDbi | Q7Z4U5 |
PRIDEi | Q7Z4U5 |
ProteomicsDBi | 69242 [Q7Z4U5-2] 69243 [Q7Z4U5-3] |
Protocols and materials databases
Antibodypediai | 52893, 54 antibodies |
DNASUi | 404220 |
Genome annotation databases
Ensembli | ENST00000380175; ENSP00000420610; ENSG00000185689 [Q7Z4U5-2] |
GeneIDi | 404220 |
KEGGi | hsa:404220 |
UCSCi | uc003mwa.5, human [Q7Z4U5-2] |
Organism-specific databases
CTDi | 404220 |
EuPathDBi | HostDB:ENSG00000185689.15 |
GeneCardsi | C6orf201 |
HGNCi | HGNC:21620, C6orf201 |
HPAi | ENSG00000185689, Tissue enriched (testis) |
neXtProti | NX_Q7Z4U5 |
OpenTargetsi | ENSG00000185689 |
PharmGKBi | PA134906041 |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | ENOG502S904, Eukaryota |
GeneTreei | ENSGT00390000008360 |
HOGENOMi | CLU_136293_0_0_1 |
InParanoidi | Q7Z4U5 |
OMAi | GISEPTW |
OrthoDBi | 1234300at2759 |
PhylomeDBi | Q7Z4U5 |
TreeFami | TF341213 |
Enzyme and pathway databases
PathwayCommonsi | Q7Z4U5 |
Miscellaneous databases
BioGRID-ORCSi | 404220, 0 hits in 837 CRISPR screens |
ChiTaRSi | C6orf201, human |
GenomeRNAii | 404220 |
Pharosi | Q7Z4U5, Tdark |
PROi | PR:Q7Z4U5 |
RNActi | Q7Z4U5, protein |
Gene expression databases
Bgeei | ENSG00000185689, Expressed in sperm and 115 other tissues |
Genevisiblei | Q7Z4U5, HS |
Family and domain databases
InterProi | View protein in InterPro IPR027827, DUF4523 |
PANTHERi | PTHR35968, PTHR35968, 1 hit |
Pfami | View protein in Pfam PF15023, DUF4523, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | CF201_HUMAN | |
Accessioni | Q7Z4U5Primary (citable) accession number: Q7Z4U5 Secondary accession number(s): A6NLI6, Q6NXN5 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | August 21, 2007 |
Last sequence update: | April 5, 2011 | |
Last modified: | December 2, 2020 | |
This is version 105 of the entry and version 3 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Human chromosome 6
Human chromosome 6: entries, gene names and cross-references to MIM - Human polymorphisms and disease mutations
Index of human polymorphisms and disease mutations - Human entries with polymorphisms or disease mutations
List of human entries with polymorphisms or disease mutations