Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Pogo transposable element with ZNF domain

Gene

POGZ

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Plays a role in mitotic cell cycle progression and is involved in kinetochore assembly and mitotic sister chromatid cohesion. Probably through its association with CBX5 plays a role in mitotic chromosome segregation by regulating aurora kinase B/AURKB activation and AURKB and CBX5 dissociation from chromosome arms.1 Publication

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri375 – 397C2H2-type 1; atypicalPROSITE-ProRule annotationAdd BLAST23
Zinc fingeri494 – 516C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri530 – 553C2H2-type 3PROSITE-ProRule annotationAdd BLAST24
Zinc fingeri560 – 583C2H2-type 4PROSITE-ProRule annotationAdd BLAST24
Zinc fingeri590 – 613C2H2-type 5PROSITE-ProRule annotationAdd BLAST24
Zinc fingeri619 – 641C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri647 – 670C2H2-type 7PROSITE-ProRule annotationAdd BLAST24
Zinc fingeri771 – 794C2H2-type 8PROSITE-ProRule annotationAdd BLAST24
Zinc fingeri815 – 840C2H2-type 9PROSITE-ProRule annotationAdd BLAST26

GO - Molecular functioni

GO - Biological processi

  • cell division Source: UniProtKB-KW
  • kinetochore assembly Source: UniProtKB
  • mitotic sister chromatid cohesion Source: UniProtKB

Keywordsi

Molecular functionDNA-binding
Biological processCell cycle, Cell division
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Pogo transposable element with ZNF domain
Alternative name(s):
Suppressor of hairy wing homolog 5
Zinc finger protein 280E
Zinc finger protein 635
Gene namesi
Name:POGZ
Synonyms:KIAA0461, SUHW5, ZNF280E, ZNF635
ORF Names:Nbla00003
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 1

Organism-specific databases

EuPathDBiHostDB:ENSG00000143442.21
HGNCiHGNC:18801 POGZ
MIMi614787 gene
neXtProtiNX_Q7Z3K3

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Chromosome, Cytoplasm, Nucleus

Pathology & Biotechi

Involvement in diseasei

Defects in POGZ may be associated with neuropsychiatric disorders such as autism spectrum disorders (ASD), bipolar affective disorders and early dementia onset. ASD are characterized by impairments in reciprocal social interaction and communication as well as restricted and stereotyped patterns of interest and activities. ASD include forms with moderate to severe cognitive impairment and milder forms with higher cognitive ability (Asperger syndrome).1 Publication
White-Sutton syndrome (WHSUS)2 Publications
The disease is caused by mutations affecting the gene represented in this entry.
Disease descriptionA mental retardation syndrome characterized by developmental delay, intellectual disability, hypotonia, behavioral abnormalities, and dysmorphic facial features. Variable features include short stature, microcephaly, strabismus and hearing loss.
See also OMIM:616364

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Mutagenesisi817C → A: Diminishes interaction with CBX5 and abolishes interaction with CBX1 and CBX5; when associated with A-820; A-833 and A-840. 1 Publication1
Mutagenesisi820C → A: Abolishes interaction with CBX1, CBX3 and CBX5; when associated with when associated with A-817; A-833 and A-840. 1 Publication1
Mutagenesisi833H → A: Abolishes interaction with CBX1, CBX3 and CBX5; when associated with A-817; A-820 and A-840. 1 Publication1
Mutagenesisi840H → A: Abolishes interaction with CBX1, CBX3 and CBX5; when associated with A-817; A-820 and A-833. 1 Publication1

Keywords - Diseasei

Autism spectrum disorder, Disease mutation, Mental retardation

Organism-specific databases

DisGeNETi23126
MalaCardsiPOGZ
MIMi616364 phenotype
OpenTargetsiENSG00000143442
PharmGKBiPA38685

Polymorphism and mutation databases

BioMutaiPOGZ
DMDMi143811442

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000472241 – 1410Pogo transposable element with ZNF domainAdd BLAST1410

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Cross-linki319Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Modified residuei333PhosphoserineCombined sources1
Cross-linki359Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Modified residuei363PhosphoserineCombined sources1
Cross-linki422Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Modified residuei425PhosphoserineCombined sources1
Modified residuei439PhosphothreonineCombined sources1
Modified residuei445PhosphoserineCombined sources1
Cross-linki449Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Modified residuei463PhosphothreonineCombined sources1
Cross-linki489Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Cross-linki629Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Cross-linki677Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Cross-linki801Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Modified residuei856PhosphoserineCombined sources1
Cross-linki883Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Modified residuei1338PhosphoserineCombined sources1
Modified residuei1364PhosphoserineCombined sources1
Modified residuei1367PhosphoserineCombined sources1
Modified residuei1368PhosphothreonineCombined sources1
Modified residuei1392PhosphoserineCombined sources1

Keywords - PTMi

Isopeptide bond, Phosphoprotein, Ubl conjugation

Proteomic databases

EPDiQ7Z3K3
MaxQBiQ7Z3K3
PaxDbiQ7Z3K3
PeptideAtlasiQ7Z3K3
PRIDEiQ7Z3K3
ProteomicsDBi69059
69060 [Q7Z3K3-2]
69061 [Q7Z3K3-3]
69062 [Q7Z3K3-4]
69063 [Q7Z3K3-5]

PTM databases

iPTMnetiQ7Z3K3
PhosphoSitePlusiQ7Z3K3

Expressioni

Gene expression databases

BgeeiENSG00000143442
CleanExiHS_POGZ
ExpressionAtlasiQ7Z3K3 baseline and differential
GenevisibleiQ7Z3K3 HS

Organism-specific databases

HPAiHPA006800
HPA008781

Interactioni

Subunit structurei

Interacts with CBX1, CBX3, MAD2L2 and CHAMP1. Interacts with CBX5; POGZ competes with PXVXL motif-containing proteins such as INCENP and TRIM28 for interaction with CBX5. Interacts with PSIP1 isoform 1.4 Publications

Binary interactionsi

Show more details

Protein-protein interaction databases

BioGridi116745, 55 interactors
DIPiDIP-38044N
IntActiQ7Z3K3, 148 interactors
MINTiQ7Z3K3
STRINGi9606.ENSP00000271715

Structurei

Secondary structure

11410
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Turni378 – 380Combined sources3
Helixi387 – 397Combined sources11
Turni399 – 401Combined sources3

3D structure databases

ProteinModelPortaliQ7Z3K3
SMRiQ7Z3K3
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ7Z3K3

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1015 – 1085HTH CENPB-typePROSITE-ProRule annotationAdd BLAST71
Domaini1117 – 1323DDE-1Sequence analysisAdd BLAST207

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni810 – 850Required for interaction with CBX5Add BLAST41

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili1340 – 1360Sequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi875 – 931Pro-richAdd BLAST57

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri375 – 397C2H2-type 1; atypicalPROSITE-ProRule annotationAdd BLAST23
Zinc fingeri494 – 516C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri530 – 553C2H2-type 3PROSITE-ProRule annotationAdd BLAST24
Zinc fingeri560 – 583C2H2-type 4PROSITE-ProRule annotationAdd BLAST24
Zinc fingeri590 – 613C2H2-type 5PROSITE-ProRule annotationAdd BLAST24
Zinc fingeri619 – 641C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri647 – 670C2H2-type 7PROSITE-ProRule annotationAdd BLAST24
Zinc fingeri771 – 794C2H2-type 8PROSITE-ProRule annotationAdd BLAST24
Zinc fingeri815 – 840C2H2-type 9PROSITE-ProRule annotationAdd BLAST26

Keywords - Domaini

Coiled coil, Repeat, Zinc-finger

Phylogenomic databases

eggNOGiKOG1721 Eukaryota
KOG3105 Eukaryota
COG5048 LUCA
GeneTreeiENSGT00530000063300
HOGENOMiHOG000010309
HOVERGENiHBG049435
InParanoidiQ7Z3K3
KOiK22594
OMAiGLTWISH
OrthoDBiEOG091G01UE
PhylomeDBiQ7Z3K3
TreeFamiTF331707

Family and domain databases

InterProiView protein in InterPro
IPR004875 DDE_SF_endonuclease_dom
IPR009057 Homeobox-like_sf
IPR006600 HTH_CenpB_DNA-bd_dom
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
PfamiView protein in Pfam
PF03184 DDE_1, 1 hit
PF03221 HTH_Tnp_Tc5, 1 hit
SMARTiView protein in SMART
SM00674 CENPB, 1 hit
SM00355 ZnF_C2H2, 8 hits
SUPFAMiSSF46689 SSF46689, 1 hit
SSF57667 SSF57667, 2 hits
PROSITEiView protein in PROSITE
PS51253 HTH_CENPB, 1 hit
PS00028 ZINC_FINGER_C2H2_1, 5 hits
PS50157 ZINC_FINGER_C2H2_2, 2 hits

Sequences (7)i

Sequence statusi: Complete.

This entry describes 7 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 1 (identifier: Q7Z3K3-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MADTDLFMEC EEEELEPWQK ISDVIEDSVV EDYNSVDKTT TVSVSQQPVS
60 70 80 90 100
APVPIAAHAS VAGHLSTSTT VSSSGAQNSD STKKTLVTLI ANNNAGNPLV
110 120 130 140 150
QQGGQPLILT QNPAPGLGTM VTQPVLRPVQ VMQNANHVTS SPVASQPIFI
160 170 180 190 200
TTQGFPVRNV RPVQNAMNQV GIVLNVQQGQ TVRPITLVPA PGTQFVKPTV
210 220 230 240 250
GVPQVFSQMT PVRPGSTMPV RPTTNTFTTV IPATLTIRST VPQSQSQQTK
260 270 280 290 300
STPSTSTTPT ATQPTSLGQL AVQSPGQSNQ TTNPKLAPSF PSPPAVSIAS
310 320 330 340 350
FVTVKRPGVT GENSNEVAKL VNTLNTIPSL GQSPGPVVVS NNSSAHGSQR
360 370 380 390 400
TSGPESSMKV TSSIPVFDLQ DGGRKICPRC NAQFRVTEAL RGHMCYCCPE
410 420 430 440 450
MVEYQKKGKS LDSEPSVPSA AKPPSPEKTA PVASTPSSTP IPALSPPTKV
460 470 480 490 500
PEPNENVGDA VQTKLIMLVD DFYYGRDGGK VAQLTNFPKV ATSFRCPHCT
510 520 530 540 550
KRLKNNIRFM NHMKHHVELD QQNGEVDGHT ICQHCYRQFS TPFQLQCHLE
560 570 580 590 600
NVHSPYESTT KCKICEWAFE SEPLFLQHMK DTHKPGEMPY VCQVCQYRSS
610 620 630 640 650
LYSEVDVHFR MIHEDTRHLL CPYCLKVFKN GNAFQQHYMR HQKRNVYHCN
660 670 680 690 700
KCRLQFLFAK DKIEHKLQHH KTFRKPKQLE GLKPGTKVTI RASRGQPRTV
710 720 730 740 750
PVSSNDTPPS ALQEAAPLTS SMDPLPVFLY PPVQRSIQKR AVRKMSVMGR
760 770 780 790 800
QTCLECSFEI PDFPNHFPTY VHCSLCRYST CCSRAYANHM INNHVPRKSP
810 820 830 840 850
KYLALFKNSV SGIKLACTSC TFVTSVGDAM AKHLVFNPSH RSSSILPRGL
860 870 880 890 900
TWIAHSRHGQ TRDRVHDRNV KNMYPPPSFP TNKAATVKSA GATPAEPEEL
910 920 930 940 950
LTPLAPALPS PASTATPPPT PTHPQALALP PLATEGAECL NVDDQDEGSP
960 970 980 990 1000
VTQEPELASG GGGSGGVGKK EQLSVKKLRV VLFALCCNTE QAAEHFRNPQ
1010 1020 1030 1040 1050
RRIRRWLRRF QASQGENLEG KYLSFEAEEK LAEWVLTQRE QQLPVNEETL
1060 1070 1080 1090 1100
FQKATKIGRS LEGGFKISYE WAVRFMLRHH LTPHARRAVA HTLPKDVAEN
1110 1120 1130 1140 1150
AGLFIDFVQR QIHNQDLPLS MIVAIDEISL FLDTEVLSSD DRKENALQTV
1160 1170 1180 1190 1200
GTGEPWCDVV LAILADGTVL PTLVFYRGQM DQPANMPDSI LLEAKESGYS
1210 1220 1230 1240 1250
DDEIMELWST RVWQKHTACQ RSKGMLVMDC HRTHLSEEVL AMLSASSTLP
1260 1270 1280 1290 1300
AVVPAGCSSK IQPLDVCIKR TVKNFLHKKW KEQAREMADT ACDSDVLLQL
1310 1320 1330 1340 1350
VLVWLGEVLG VIGDCPELVQ RSFLVASVLP GPDGNINSPT RNADMQEELI
1360 1370 1380 1390 1400
ASLEEQLKLS GEHSESSTPR PRSSPEETIE PESLHQLFEG ESETESFYGF
1410
EEADLDLMEI
Length:1,410
Mass (Da):155,344
Last modified:April 3, 2007 - v2
Checksum:i58F672EDCD57CCD8
GO
Isoform 2 (identifier: Q7Z3K3-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     42-94: Missing.

Note: No experimental confirmation available.
Show »
Length:1,357
Mass (Da):150,130
Checksum:i3EC92965C8E95A98
GO
Isoform 3 (identifier: Q7Z3K3-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     42-94: Missing.
     593-593: Q → QPYFPSYVTQ

Note: No experimental confirmation available.
Show »
Length:1,366
Mass (Da):151,213
Checksum:iC88635F4469B70AA
GO
Isoform 4 (identifier: Q7Z3K3-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     360-363: VTSS → GTIT
     364-1410: Missing.

Note: No experimental confirmation available.
Show »
Length:363
Mass (Da):37,882
Checksum:iE4CA34C166CC3E78
GO
Isoform 5 (identifier: Q7Z3K3-5) [UniParc]FASTAAdd to basket
Also known as: CRA_e

The sequence of this isoform differs from the canonical sequence as follows:
     96-190: Missing.

Note: Gene prediction based on EST data.
Show »
Length:1,315
Mass (Da):145,295
Checksum:i457D70CDC875B81C
GO
Isoform 6 (identifier: Q7Z3K3-6) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     287-295: Missing.

Show »
Length:1,401
Mass (Da):154,492
Checksum:i99537C2A84842376
GO
Isoform 7 (identifier: Q7Z3K3-7) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     42-94: Missing.
     287-295: Missing.

Show »
Length:1,348
Mass (Da):149,278
Checksum:i0016C4CF1C9CB146
GO

Sequence cautioni

The sequence BAE45744 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated
The sequence CAI16808 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence CAI16810 differs from that shown. Reason: Erroneous gene model prediction.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti213R → G in BAG63781 (PubMed:14702039).Curated1
Sequence conflicti327I → F in BAG62060 (PubMed:14702039).Curated1
Sequence conflicti503L → P in BAB87117 (PubMed:12880961).Curated1
Sequence conflicti503L → P in BAE45744 (PubMed:12880961).Curated1
Sequence conflicti727V → A in BAG63781 (PubMed:14702039).Curated1
Sequence conflicti788N → T in CAB45136 (PubMed:10976766).Curated1
Sequence conflicti888K → E in BAB87117 (PubMed:12880961).Curated1
Sequence conflicti888K → E in BAE45744 (PubMed:12880961).Curated1
Sequence conflicti933A → V in CAD97850 (PubMed:17974005).Curated1
Sequence conflicti1026E → G in CAD97850 (PubMed:17974005).Curated1
Sequence conflicti1078R → W in BAB87117 (PubMed:12880961).Curated1
Sequence conflicti1078R → W in BAE45744 (PubMed:12880961).Curated1
Sequence conflicti1092 – 1107TLPKD…LFIDF → PTLLFCLFVFSSPSTL in BAB87117 (PubMed:12880961).CuratedAdd BLAST16
Sequence conflicti1092 – 1107TLPKD…LFIDF → PTLLFCLFVFSSPSTL in BAE45744 (PubMed:12880961).CuratedAdd BLAST16
Sequence conflicti1248T → A in BAG63781 (PubMed:14702039).Curated1
Sequence conflicti1304W → R in CAD97850 (PubMed:17974005).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_0731791040E → K Probable disease-associated mutation found in patients with ASD. 1 Publication1
Natural variantiVAR_0314761365E → D. Corresponds to variant dbSNP:rs35198305Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_01018542 – 94Missing in isoform 2, isoform 3 and isoform 7. 3 PublicationsAdd BLAST53
Alternative sequenceiVSP_03015096 – 190Missing in isoform 5. CuratedAdd BLAST95
Alternative sequenceiVSP_046785287 – 295Missing in isoform 6 and isoform 7. 1 Publication9
Alternative sequenceiVSP_010187360 – 363VTSS → GTIT in isoform 4. 1 Publication4
Alternative sequenceiVSP_010188364 – 1410Missing in isoform 4. 1 PublicationAdd BLAST1047
Alternative sequenceiVSP_010186593Q → QPYFPSYVTQ in isoform 3. 1 Publication1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX537838 mRNA Translation: CAD97850.1
AK300307 mRNA Translation: BAG62060.1
AK302501 mRNA Translation: BAG63781.1
AL589764 Genomic DNA Translation: CAI16807.1
AL589764 Genomic DNA Translation: CAI16808.2 Sequence problems.
AL589764 Genomic DNA Translation: CAI16809.1
AL589764 Genomic DNA Translation: CAI16810.1 Sequence problems.
CH471121 Genomic DNA Translation: EAW53440.1
AB037911 mRNA Translation: BAB87117.1
AB075477 mRNA Translation: BAE45744.1 Different initiation.
AJ242979 mRNA Translation: CAB45136.1
BC057773 mRNA Translation: AAH57773.1
AB007930 mRNA Translation: BAA32306.1
CCDSiCCDS44222.2 [Q7Z3K3-5]
CCDS53365.1 [Q7Z3K3-7]
CCDS53366.1 [Q7Z3K3-6]
CCDS997.1 [Q7Z3K3-1]
CCDS998.1 [Q7Z3K3-2]
PIRiT00075
RefSeqiNP_001181866.1, NM_001194937.1 [Q7Z3K3-6]
NP_001181867.1, NM_001194938.1 [Q7Z3K3-7]
NP_055915.2, NM_015100.3 [Q7Z3K3-1]
NP_665739.3, NM_145796.3 [Q7Z3K3-5]
NP_997054.1, NM_207171.2 [Q7Z3K3-2]
XP_005245056.1, XM_005244999.2 [Q7Z3K3-1]
XP_005245057.1, XM_005245000.4 [Q7Z3K3-1]
XP_005245058.1, XM_005245001.2 [Q7Z3K3-1]
XP_005245062.1, XM_005245005.1 [Q7Z3K3-2]
XP_005245063.1, XM_005245006.4 [Q7Z3K3-2]
XP_016856234.1, XM_017000745.1 [Q7Z3K3-6]
XP_016856235.1, XM_017000746.1 [Q7Z3K3-6]
XP_016856237.1, XM_017000748.1 [Q7Z3K3-2]
XP_016856238.1, XM_017000749.1 [Q7Z3K3-2]
UniGeneiHs.489873

Genome annotation databases

EnsembliENST00000271715; ENSP00000271715; ENSG00000143442 [Q7Z3K3-1]
ENST00000368863; ENSP00000357856; ENSG00000143442 [Q7Z3K3-5]
ENST00000392723; ENSP00000376484; ENSG00000143442 [Q7Z3K3-2]
ENST00000409503; ENSP00000386836; ENSG00000143442 [Q7Z3K3-6]
ENST00000491586; ENSP00000418408; ENSG00000143442 [Q7Z3K3-3]
ENST00000531094; ENSP00000431259; ENSG00000143442 [Q7Z3K3-7]
GeneIDi23126
KEGGihsa:23126
UCSCiuc001eyd.2 human [Q7Z3K3-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

Similar proteinsi

Entry informationi

Entry nameiPOGZ_HUMAN
AccessioniPrimary (citable) accession number: Q7Z3K3
Secondary accession number(s): B4DTP8
, B4DYL9, B7ZBY5, E9PM80, O75049, Q3LIC4, Q5SZS1, Q5SZS2, Q5SZS3, Q5SZS4, Q8TDZ7, Q9Y4X7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 26, 2004
Last sequence update: April 3, 2007
Last modified: July 18, 2018
This is version 162 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health