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Entry version 138 (02 Jun 2021)
Sequence version 3 (08 Mar 2011)
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Protein

RanBP2-like and GRIP domain-containing protein 4

Gene

RGPD4

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Miscellaneous

One of the 8 copies of RANBP2 clustered close to the chromosome 2 centromere.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
Q7Z3J3

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
RanBP2-like and GRIP domain-containing protein 4
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:RGPD4
Synonyms:RGP4
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:32417, RGPD4

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
612707, gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q7Z3J3

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
HostDB:ENSG00000196862.9

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000196862

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA142671073

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q7Z3J3, Tdark

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
RGPD4

Domain mapping of disease mutations (DMDM)

More...
DMDMi
325511381

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003141411 – 1758RanBP2-like and GRIP domain-containing protein 4Add BLAST1758

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei21PhosphoserineBy similarity1

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q7Z3J3

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q7Z3J3

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q7Z3J3

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q7Z3J3

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q7Z3J3

PeptideAtlas

More...
PeptideAtlasi
Q7Z3J3

PRoteomics IDEntifications database

More...
PRIDEi
Q7Z3J3

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
69057 [Q7Z3J3-1]
69058 [Q7Z3J3-2]

PTM databases

GlyConnect protein glycosylation platform

More...
GlyConnecti
2898, 1 O-Linked glycan (1 site)

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q7Z3J3

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q7Z3J3

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000196862, Expressed in testis and 10 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q7Z3J3, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000196862, Tissue enriched (testis)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
130039, 7 interactors

Protein interaction database and analysis system

More...
IntActi
Q7Z3J3, 2 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000386810

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q7Z3J3, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q7Z3J3

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati60 – 93TPR 1Add BLAST34
Repeati584 – 617TPR 2Add BLAST34
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1037 – 1173RanBD1 1PROSITE-ProRule annotationAdd BLAST137
Domaini1334 – 1470RanBD1 2PROSITE-ProRule annotationAdd BLAST137
Domaini1703 – 1753GRIPPROSITE-ProRule annotationAdd BLAST51

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni761 – 805DisorderedSequence analysisAdd BLAST45
Regioni1213 – 1249DisorderedSequence analysisAdd BLAST37
Regioni1295 – 1332DisorderedSequence analysisAdd BLAST38
Regioni1583 – 1621DisorderedSequence analysisAdd BLAST39

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi773 – 796Polar residuesSequence analysisAdd BLAST24
Compositional biasi1227 – 1246Polar residuesSequence analysisAdd BLAST20
Compositional biasi1295 – 1320Polar residuesSequence analysisAdd BLAST26
Compositional biasi1596 – 1613Basic and acidic residuesSequence analysisAdd BLAST18

Keywords - Domaini

Repeat, TPR repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0864, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000164065

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_004100_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q7Z3J3

Identification of Orthologs from Complete Genome Data

More...
OMAi
CERARDL

Database of Orthologous Groups

More...
OrthoDBi
1573143at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q7Z3J3

TreeFam database of animal gene trees

More...
TreeFami
TF314797

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.25.40.10, 1 hit
2.30.29.30, 2 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR032023, GCC2_Rab_bind
IPR000237, GRIP_dom
IPR011993, PH-like_dom_sf
IPR000156, Ran_bind_dom
IPR013026, TPR-contain_dom
IPR011990, TPR-like_helical_dom_sf
IPR019734, TPR_repeat

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01465, GRIP, 1 hit
PF16704, Rab_bind, 1 hit
PF00638, Ran_BP1, 2 hits
PF13181, TPR_8, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00755, Grip, 1 hit
SM00160, RanBD, 2 hits
SM00028, TPR, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48452, SSF48452, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50913, GRIP, 1 hit
PS50196, RANBD1, 2 hits
PS50005, TPR, 1 hit
PS50293, TPR_REGION, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform 1 (identifier: Q7Z3J3-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MSCSKAYGER YVASVQGSAP SPRKKSTRGF YFAKLYYEAK EYDLAKKYIC
60 70 80 90 100
TYINVREMDP RAHRFLGLLY ELEENTEKAV ECYRRSVELN PTQKDLVLKI
110 120 130 140 150
AELLCKNDVT DGRAKYWVER AAKLFPGSPA IYKLKEQLLD CEGEDGWNKL
160 170 180 190 200
FDLIQSELYV RPDDVHVNIR LVELYRSTKR LKDAVARCHE AERNIALRSS
210 220 230 240 250
LEWNSCVVQT LKEYLESLQC LESDKSDWRA TNTDLLLAYA NLMLLTLSTR
260 270 280 290 300
DVQESRELLE SFDSALQSAK SSLGGNDELS ATFLEMKGHF YMHAGSLLLK
310 320 330 340 350
MGQHGNNVQW RALSELAALC YLIAFQVPRP KIKLIKGEAG QNLLEMMACD
360 370 380 390 400
RLSQSGHMLL NLSRGKQDFL KVVVETFANK SGQSALYDAL FSSQSPKDTS
410 420 430 440 450
FLGSDDIGNI DVQEPELEDL ARYDVGAIRA HNGSLQHLTW LGLQWNSLPA
460 470 480 490 500
LPGIRKWLKQ LFHHLPQETS RLETNAPESI CILDLEVFLL GVVYTSHLQL
510 520 530 540 550
KEKCNSHHSS YQPLCLPLPV CKQLCTERQK SWWDAVCTLI HRKAVPGNSA
560 570 580 590 600
KLRLLVQHEI NTLRAQEKHG LQPALLVHWA KCLQKMGSGL NSFYDQREYI
610 620 630 640 650
GRSVHYWKKV LPLLKIIKKK NSIPEPIDPL FKHFHSVDIQ ASEIVEYEED
660 670 680 690 700
AHVTFAILDA VNGNIEDAMT AFESIKSVVS YWNLALIFHR KAEDIANDAL
710 720 730 740 750
SPEEQEECKN YLRKTRGYLI KILDDSDSNL SVVKKLPVPL ESVKEMLKSV
760 770 780 790 800
MQELENYSEG DPLYKNGSLR NADSEIKHST PSPTKYSLSP SKSYKYSPKT
810 820 830 840 850
PPRWAEDQNS LLKMIRQEVK AIKEEMQELK LNSSKSASHH RWPTENYGPD
860 870 880 890 900
SVPDGYQGSQ TFHGAPLTVA TTGPSVYYSQ SPAYNSQYLL RPAANVTPTK
910 920 930 940 950
GSSNTEFKST KEGFSIPVSA DGFKFGISEP GNQEKESEKP LENDTGFQAQ
960 970 980 990 1000
DISGQKNGRG VIFGQTSSTF TFADVAKSTS GEGFQFGKKD PNFKGFSGAG
1010 1020 1030 1040 1050
EKLFSSQCGK MANKANTSGD FEKDDDAYKT EDSDDIHFEP VVQMPEKVEL
1060 1070 1080 1090 1100
VIGEEGEKVL YSQGVKLFRF DAEVRQWKER GLGNLKILKN EVNGKPRMLM
1110 1120 1130 1140 1150
RREQVLKVCA NHWITTTMNL KPLSGSDRAW MWSASDFSDG DAKLERLAAK
1160 1170 1180 1190 1200
FKTPELAEEF KQKFEECQQL LLDIPLQTPH KLVDTGRAAK LIQRAEEMKS
1210 1220 1230 1240 1250
GLKDFKTFLT NDQTKVTEEE NKGSGTGAAG ASDTTIKPNP ENTGPTLEWD
1260 1270 1280 1290 1300
NCDLREDALD DSVSSSSVHA SPLASSPVRK NLFHFGESTT GSNFSFKSAL
1310 1320 1330 1340 1350
SPSKSPAKLN QSGTSVGTDE ESDVTQEEER DGQYFEPVVP LPDLVEVSSG
1360 1370 1380 1390 1400
EENEKVVFSH RAELYRYDKD VGQWKERGIG DIKILQNYDN KQVRIVMRRD
1410 1420 1430 1440 1450
QVLKLCANHT ITPDMSLQNM KGTERVWVWT ACDFADGERK VEHLAVRFKL
1460 1470 1480 1490 1500
QDVADSFKKI FDEAKTAQEK DSLITPHVSR SSTPRESPCG KIAVAVLEET
1510 1520 1530 1540 1550
TRERTDVIQG DDVADAASEV EVSSTSETTT KAVVSPPKFV FGSESVKRIF
1560 1570 1580 1590 1600
SSEKSKPFAF GNSSATGSLF GFSFNASLKS NNSETSSVAQ SGSESKVEPK
1610 1620 1630 1640 1650
KCELSKNSDI EQSSDSKVKN LSASFPMEES SINYTFKTPE KEPPLWHAEF
1660 1670 1680 1690 1700
TKEELVQKLS STTKSADHLN GLLREAEATS AVLMEQIKLL KSEIRRLERN
1710 1720 1730 1740 1750
QEQEESAANV EHLKNVLLQF IFLKPGSERE RLLPVINTML QLSPEEKGKL

AAVAQGEE
Length:1,758
Mass (Da):197,289
Last modified:March 8, 2011 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i03C915030A2F1BD3
GO
Isoform 2 (identifier: Q7Z3J3-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-57: Missing.
     213-1758: Missing.

Show »
Length:155
Mass (Da):18,065
Checksum:i5E0243B7276A4CF3
GO

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0302141 – 57Missing in isoform 2. 1 PublicationAdd BLAST57
Alternative sequenceiVSP_030215213 – 1758Missing in isoform 2. 1 PublicationAdd BLAST1546

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
BX537861 mRNA Translation: CAD97866.1
AC009963 Genomic DNA No translation available.
AC096655 Genomic DNA No translation available.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS46381.1 [Q7Z3J3-1]

NCBI Reference Sequences

More...
RefSeqi
NP_872394.2, NM_182588.2 [Q7Z3J3-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000408999; ENSP00000386810; ENSG00000196862 [Q7Z3J3-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
285190

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:285190

UCSC genome browser

More...
UCSCi
uc010ywk.3, human [Q7Z3J3-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX537861 mRNA Translation: CAD97866.1
AC009963 Genomic DNA No translation available.
AC096655 Genomic DNA No translation available.
CCDSiCCDS46381.1 [Q7Z3J3-1]
RefSeqiNP_872394.2, NM_182588.2 [Q7Z3J3-1]

3D structure databases

SMRiQ7Z3J3
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi130039, 7 interactors
IntActiQ7Z3J3, 2 interactors
STRINGi9606.ENSP00000386810

PTM databases

GlyConnecti2898, 1 O-Linked glycan (1 site)
iPTMnetiQ7Z3J3
PhosphoSitePlusiQ7Z3J3

Genetic variation databases

BioMutaiRGPD4
DMDMi325511381

Proteomic databases

EPDiQ7Z3J3
jPOSTiQ7Z3J3
MassIVEiQ7Z3J3
MaxQBiQ7Z3J3
PaxDbiQ7Z3J3
PeptideAtlasiQ7Z3J3
PRIDEiQ7Z3J3
ProteomicsDBi69057 [Q7Z3J3-1]
69058 [Q7Z3J3-2]

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
285190

Genome annotation databases

EnsembliENST00000408999; ENSP00000386810; ENSG00000196862 [Q7Z3J3-1]
GeneIDi285190
KEGGihsa:285190
UCSCiuc010ywk.3, human [Q7Z3J3-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
285190

GeneCards: human genes, protein and diseases

More...
GeneCardsi
RGPD4
HGNCiHGNC:32417, RGPD4
HPAiENSG00000196862, Tissue enriched (testis)
MIMi612707, gene
neXtProtiNX_Q7Z3J3
OpenTargetsiENSG00000196862
PharmGKBiPA142671073
VEuPathDBiHostDB:ENSG00000196862.9

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG0864, Eukaryota
GeneTreeiENSGT00940000164065
HOGENOMiCLU_004100_0_0_1
InParanoidiQ7Z3J3
OMAiCERARDL
OrthoDBi1573143at2759
PhylomeDBiQ7Z3J3
TreeFamiTF314797

Enzyme and pathway databases

PathwayCommonsiQ7Z3J3

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

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BioGRID-ORCSi
285190, 36 hits in 910 CRISPR screens

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
285190
PharosiQ7Z3J3, Tdark

Protein Ontology

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PROi
PR:Q7Z3J3
RNActiQ7Z3J3, protein

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSG00000196862, Expressed in testis and 10 other tissues
GenevisibleiQ7Z3J3, HS

Family and domain databases

Gene3Di1.25.40.10, 1 hit
2.30.29.30, 2 hits
InterProiView protein in InterPro
IPR032023, GCC2_Rab_bind
IPR000237, GRIP_dom
IPR011993, PH-like_dom_sf
IPR000156, Ran_bind_dom
IPR013026, TPR-contain_dom
IPR011990, TPR-like_helical_dom_sf
IPR019734, TPR_repeat
PfamiView protein in Pfam
PF01465, GRIP, 1 hit
PF16704, Rab_bind, 1 hit
PF00638, Ran_BP1, 2 hits
PF13181, TPR_8, 1 hit
SMARTiView protein in SMART
SM00755, Grip, 1 hit
SM00160, RanBD, 2 hits
SM00028, TPR, 1 hit
SUPFAMiSSF48452, SSF48452, 1 hit
PROSITEiView protein in PROSITE
PS50913, GRIP, 1 hit
PS50196, RANBD1, 2 hits
PS50005, TPR, 1 hit
PS50293, TPR_REGION, 1 hit

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiRGPD4_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q7Z3J3
Secondary accession number(s): B9A029
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: March 8, 2011
Last modified: June 2, 2021
This is version 138 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 2
    Human chromosome 2: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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