Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 146 (12 Aug 2020)
Sequence version 1 (01 Oct 2003)
Previous versions | rss
Help videoAdd a publicationFeedback
Protein

Zinc finger protein 572

Gene

ZNF572

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May be involved in transcriptional regulation.By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri132 – 154C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri160 – 182C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri188 – 210C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri216 – 238C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri244 – 266C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri272 – 294C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri300 – 322C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri328 – 350C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri384 – 406C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri412 – 434C2H2-type 10PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri440 – 462C2H2-type 11PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri468 – 490C2H2-type 12PROSITE-ProRule annotationAdd BLAST23

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
Q7Z3I7

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Zinc finger protein 572
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ZNF572
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 8

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000180938.5

Human Gene Nomenclature Database

More...
HGNCi
HGNC:26758, ZNF572

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q7Z3I7

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
137209

Open Targets

More...
OpenTargetsi
ENSG00000180938

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134924678

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q7Z3I7, Tdark

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
ZNF572

Domain mapping of disease mutations (DMDM)

More...
DMDMi
74762429

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002512231 – 529Zinc finger protein 572Add BLAST529

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section describes <strong>covalent linkages</strong> of various types formed <strong>between two proteins (interchain cross-links)</strong> or <strong>between two parts of the same protein (intrachain cross-links)</strong>, except the disulfide bonds that are annotated in the <a href="http://www.uniprot.org/manual/disulfid">'Disulfide bond'</a> subsection.<p><a href='/help/crosslnk' target='_top'>More...</a></p>Cross-linki5Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Cross-linki6Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources

Keywords - PTMi

Isopeptide bond, Ubl conjugation

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q7Z3I7

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q7Z3I7

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q7Z3I7

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q7Z3I7

PeptideAtlas

More...
PeptideAtlasi
Q7Z3I7

PRoteomics IDEntifications database

More...
PRIDEi
Q7Z3I7

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
69054

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q7Z3I7

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q7Z3I7

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000180938, Expressed in testis and 124 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q7Z3I7, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000180938, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Q7Z3I7
With#Exp.IntAct
BEGAIN [Q9BUH8]5EBI-10172590,EBI-742722
BOLA1 [Q9Y3E2]3EBI-10172590,EBI-1049556
CADPS - isoform 4 [Q9ULU8-4]3EBI-10172590,EBI-10180690
CARD9 [Q9H257]7EBI-10172590,EBI-751319
CARD9 - isoform 2 [Q9H257-2]3EBI-10172590,EBI-11530605
CBY2 - isoform 2 [Q8NA61-2]3EBI-10172590,EBI-11524851
CCDC102B [Q68D86]6EBI-10172590,EBI-10171570
CCDC130 [P13994]9EBI-10172590,EBI-716093
CCDC136 - isoform 2 [Q96JN2-2]6EBI-10172590,EBI-10171416
CDR2L [Q86X02]3EBI-10172590,EBI-11063830
CEP57L1 [Q8IYX8]4EBI-10172590,EBI-1104570
CEP70 [Q8NHQ1]6EBI-10172590,EBI-739624
CPNE7 - isoform 2 [Q9UBL6-2]3EBI-10172590,EBI-12012272
DEUP1 [Q05D60]9EBI-10172590,EBI-748597
FAM214B [Q7L5A3]3EBI-10172590,EBI-745689
FSD2 [A1L4K1]7EBI-10172590,EBI-5661036
GAS8 [O95995]3EBI-10172590,EBI-1052570
GOLGA2 [Q08379]6EBI-10172590,EBI-618309
GPR50 [Q13585]3EBI-10172590,EBI-8550965
HAP1 [P54257]3EBI-10172590,EBI-712814
HOOK1 [Q9UJC3]3EBI-10172590,EBI-746704
HOOK2 - isoform 2 [Q96ED9-2]3EBI-10172590,EBI-10961706
IL16 - isoform 2 [Q14005-2]3EBI-10172590,EBI-17178971
KATNBL1 [Q9H079]5EBI-10172590,EBI-715394
KIF9 [Q9HAQ2]3EBI-10172590,EBI-8472129
KIFC3 [Q9BVG8]6EBI-10172590,EBI-2125614
KIFC3 - isoform 4 [Q9BVG8-5]4EBI-10172590,EBI-14069005
KLC3 [Q6P597]3EBI-10172590,EBI-1643885
KRT31 [Q15323]3EBI-10172590,EBI-948001
KRTAP10-5 [P60370]3EBI-10172590,EBI-10172150
KRTAP10-7 [P60409]3EBI-10172590,EBI-10172290
KRTAP10-8 [P60410]9EBI-10172590,EBI-10171774
KRTAP10-9 [P60411]6EBI-10172590,EBI-10172052
LZTS1 [Q9Y250]3EBI-10172590,EBI-1216080
LZTS2 [Q9BRK4]6EBI-10172590,EBI-741037
MDFI [Q99750]3EBI-10172590,EBI-724076
MEOX2 [P50222]3EBI-10172590,EBI-748397
MLLT3 [P42568]3EBI-10172590,EBI-716132
MTUS2 [Q5JR59]6EBI-10172590,EBI-742948
MTUS2 - isoform 2 [Q5JR59-3]3EBI-10172590,EBI-11522433
NDEL1 [Q9GZM8]3EBI-10172590,EBI-928842
PRPH [P41219]3EBI-10172590,EBI-752074
REL [Q04864]3EBI-10172590,EBI-307352
SPAG5 [Q96R06]3EBI-10172590,EBI-413317
TFIP11 [Q9UBB9]3EBI-10172590,EBI-1105213
TRAF1 [Q13077]6EBI-10172590,EBI-359224
TRAF2 [Q12933]3EBI-10172590,EBI-355744
TRIM27 [P14373]6EBI-10172590,EBI-719493
TRIM54 [Q9BYV2]9EBI-10172590,EBI-2130429
VIM [P08670]3EBI-10172590,EBI-353844
WTAP [Q15007]3EBI-10172590,EBI-751647
ZBTB1 [Q9Y2K1]3EBI-10172590,EBI-2682961
ZBTB8A [Q96BR9]3EBI-10172590,EBI-742740
ZNF165 [P49910]3EBI-10172590,EBI-741694
ZNF250 - isoform 3 [P15622-3]3EBI-10172590,EBI-10177272
ZNF383 [Q8NA42]3EBI-10172590,EBI-20110775
ZNF417 [Q8TAU3]3EBI-10172590,EBI-740727
ZNF57 [Q68EA5]3EBI-10172590,EBI-8490788
itself3EBI-10172590,EBI-10172590
ZNF774 [Q6NX45]3EBI-10172590,EBI-10251462
ZNF835 [Q9Y2P0]3EBI-10172590,EBI-5667516

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
126473, 29 interactors

Protein interaction database and analysis system

More...
IntActi
Q7Z3I7, 59 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000319305

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q7Z3I7, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q7Z3I7

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri132 – 154C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri160 – 182C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri188 – 210C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri216 – 238C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri244 – 266C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri272 – 294C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri300 – 322C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri328 – 350C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri384 – 406C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri412 – 434C2H2-type 10PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri440 – 462C2H2-type 11PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri468 – 490C2H2-type 12PROSITE-ProRule annotationAdd BLAST23

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1721, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000162935

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_002678_10_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q7Z3I7

Identification of Orthologs from Complete Genome Data

More...
OMAi
HEWTWKN

Database of Orthologous Groups

More...
OrthoDBi
1318335at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q7Z3I7

TreeFam database of animal gene trees

More...
TreeFami
TF341767

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR036236, Znf_C2H2_sf
IPR013087, Znf_C2H2_type

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00096, zf-C2H2, 11 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00355, ZnF_C2H2, 12 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF57667, SSF57667, 7 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00028, ZINC_FINGER_C2H2_1, 12 hits
PS50157, ZINC_FINGER_C2H2_2, 12 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q7Z3I7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEQEKKLLVS DSNSFMERES LKSPFTGDTS MNNLETVHHN NSKADKLKEK
60 70 80 90 100
PSEWSKRHRP QHYKHEDAKE MPLTWVQDEI WCHDSYESDG KSENWGNFIA
110 120 130 140 150
KEEEKPNHQE WDSGEHTNAC VQQNSSFVDR PYKCSECWKS FSNSSHLRTH
160 170 180 190 200
QRTHSGEKPY KCSECAKCFC NSSHLIQHLR MHTGEKPYQC GECGKSFSNT
210 220 230 240 250
SHLIIHERTH TGEKPYKCPE CGKRFSSSSH LIQHHRSHTG EKPYECSVCG
260 270 280 290 300
KGFSHSYVLI EHQRTHTGEK PYKCPDCGKS FSQSSSLIRH QRTHTGEKPY
310 320 330 340 350
KCLECEKSFG CNSTLIKHQR IHTGEKPYQC PECGKNFSRS SNLITHQKMH
360 370 380 390 400
TGEKSYESSE YEESLGQNCN VIEECRIQLG EKPYRCCECG KSFGLSSHLI
410 420 430 440 450
RHQRTHTGEK PYRCSECWKT FSQSSTLVIH QRTHTGEKPY KCPDCGESFS
460 470 480 490 500
QSFNLIRHRR THIGEKPYKC TSCEKCFSRS AYLSQHRKIH VEKPFESPDV
510 520
GDFPHEWTWK NCSGEMPFIS SFSVSNSSS
Length:529
Mass (Da):61,238
Last modified:October 1, 2003 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iFC729DB7BC7FED2B
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti480S → I in BAC04529 (PubMed:14702039).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_027664317K → T. Corresponds to variant dbSNP:rs10104558Ensembl.1
Natural variantiVAR_027665380G → E1 PublicationCorresponds to variant dbSNP:rs10105106Ensembl.1
Natural variantiVAR_027666448S → C1 PublicationCorresponds to variant dbSNP:rs10107774Ensembl.1
Natural variantiVAR_027667500V → I. Corresponds to variant dbSNP:rs7825375Ensembl.1
Natural variantiVAR_035591512C → F in a colorectal cancer sample; somatic mutation. 1 Publication1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK095321 mRNA Translation: BAC04529.1
BX537876 mRNA Translation: CAD97876.1
BC130515 mRNA Translation: AAI30516.1
BC130517 mRNA Translation: AAI30518.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS6354.1

NCBI Reference Sequences

More...
RefSeqi
NP_689625.2, NM_152412.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000319286; ENSP00000319305; ENSG00000180938

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
137209

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:137209

UCSC genome browser

More...
UCSCi
uc003yrr.4, human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK095321 mRNA Translation: BAC04529.1
BX537876 mRNA Translation: CAD97876.1
BC130515 mRNA Translation: AAI30516.1
BC130517 mRNA Translation: AAI30518.1
CCDSiCCDS6354.1
RefSeqiNP_689625.2, NM_152412.2

3D structure databases

SMRiQ7Z3I7
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi126473, 29 interactors
IntActiQ7Z3I7, 59 interactors
STRINGi9606.ENSP00000319305

PTM databases

iPTMnetiQ7Z3I7
PhosphoSitePlusiQ7Z3I7

Polymorphism and mutation databases

BioMutaiZNF572
DMDMi74762429

Proteomic databases

jPOSTiQ7Z3I7
MassIVEiQ7Z3I7
MaxQBiQ7Z3I7
PaxDbiQ7Z3I7
PeptideAtlasiQ7Z3I7
PRIDEiQ7Z3I7
ProteomicsDBi69054

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
27116, 117 antibodies

The DNASU plasmid repository

More...
DNASUi
137209

Genome annotation databases

EnsembliENST00000319286; ENSP00000319305; ENSG00000180938
GeneIDi137209
KEGGihsa:137209
UCSCiuc003yrr.4, human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
137209
DisGeNETi137209
EuPathDBiHostDB:ENSG00000180938.5

GeneCards: human genes, protein and diseases

More...
GeneCardsi
ZNF572
HGNCiHGNC:26758, ZNF572
HPAiENSG00000180938, Low tissue specificity
neXtProtiNX_Q7Z3I7
OpenTargetsiENSG00000180938
PharmGKBiPA134924678

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG1721, Eukaryota
GeneTreeiENSGT00940000162935
HOGENOMiCLU_002678_10_0_1
InParanoidiQ7Z3I7
OMAiHEWTWKN
OrthoDBi1318335at2759
PhylomeDBiQ7Z3I7
TreeFamiTF341767

Enzyme and pathway databases

PathwayCommonsiQ7Z3I7

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
137209, 8 hits in 895 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
ZNF572, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
137209
PharosiQ7Z3I7, Tdark

Protein Ontology

More...
PROi
PR:Q7Z3I7
RNActiQ7Z3I7, protein

Gene expression databases

BgeeiENSG00000180938, Expressed in testis and 124 other tissues
GenevisibleiQ7Z3I7, HS

Family and domain databases

InterProiView protein in InterPro
IPR036236, Znf_C2H2_sf
IPR013087, Znf_C2H2_type
PfamiView protein in Pfam
PF00096, zf-C2H2, 11 hits
SMARTiView protein in SMART
SM00355, ZnF_C2H2, 12 hits
SUPFAMiSSF57667, SSF57667, 7 hits
PROSITEiView protein in PROSITE
PS00028, ZINC_FINGER_C2H2_1, 12 hits
PS50157, ZINC_FINGER_C2H2_2, 12 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiZN572_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q7Z3I7
Secondary accession number(s): A1L4E9, A1L4F1, Q8N1Q0
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 3, 2006
Last sequence update: October 1, 2003
Last modified: August 12, 2020
This is version 146 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  2. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  3. SIMILARITY comments
    Index of protein domains and families
  4. Human chromosome 8
    Human chromosome 8: entries, gene names and cross-references to MIM
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again