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Entry version 117 (08 May 2019)
Sequence version 4 (20 Dec 2017)
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Protein

Photoreceptor ankyrin repeat protein

Gene

ANKRD33

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Acts as a transcriptional repressor for CRX-activated photoreceptor gene regulation.By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Photoreceptor ankyrin repeat proteinBy similarity
Alternative name(s):
Ankyrin repeat domain-containing protein 33Combined sources
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ANKRD33
Synonyms:C12orf7, PANKY
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 12

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:13788 ANKRD33

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q7Z3H0

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cytoplasm, Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000167612

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA25508

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
ANKRD33

Domain mapping of disease mutations (DMDM)

More...
DMDMi
296439441

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002439081 – 452Photoreceptor ankyrin repeat proteinAdd BLAST452

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q7Z3H0

PeptideAtlas

More...
PeptideAtlasi
Q7Z3H0

PRoteomics IDEntifications database

More...
PRIDEi
Q7Z3H0

ProteomicsDB human proteome resource

More...
ProteomicsDBi
69047
69048 [Q7Z3H0-2]

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000167612 Expressed in 35 organ(s), highest expression level in placenta

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q7Z3H0 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q7Z3H0 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA040013
HPA058753

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
131136, 4 interactors

Protein interaction database and analysis system

More...
IntActi
Q7Z3H0, 11 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000301190

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati94 – 123ANK 1Sequence analysisAdd BLAST30
Repeati130 – 160ANK 2Sequence analysisAdd BLAST31
Repeati164 – 193ANK 3Sequence analysisAdd BLAST30
Repeati223 – 257ANK 4Sequence analysisAdd BLAST35

Keywords - Domaini

ANK repeat, Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IG0V Eukaryota
ENOG410YB42 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00500000044852

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q7Z3H0

Identification of Orthologs from Complete Genome Data

More...
OMAi
CPQWLQP

Database of Orthologous Groups

More...
OrthoDBi
1045586at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q7Z3H0

TreeFam database of animal gene trees

More...
TreeFami
TF332022

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00204 ANK, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.25.40.20, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR002110 Ankyrin_rpt
IPR020683 Ankyrin_rpt-contain_dom
IPR036770 Ankyrin_rpt-contain_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF12796 Ank_2, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00248 ANK, 4 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48403 SSF48403, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50297 ANK_REP_REGION, 1 hit
PS50088 ANK_REPEAT, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform 2 (identifier: Q7Z3H0-2) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MKVQPSVTCV ASWGGIVHLE AFGDPVIVLR GAWAVPRVDC LIDTLRTPNA
60 70 80 90 100
SCMRKGTHLL VPCLEEEELA LHRRRLDMSE ALPCPGKETP TPGCRLGALY
110 120 130 140 150
WACVHNDPTQ LQAILDGGVS PEEATQVDSN GRTGLMVACY HGFQSVVALL
160 170 180 190 200
SHCPFLDVNQ QDKGGDTALM LAAQAGHVPL VSLLLNYYVG LDLERRDQRG
210 220 230 240 250
LTALMKAAMR NRCADLTAVD PVRGKTALEW AVLTDSFDTV WRIRQLLRRP
260 270 280 290 300
QVEQLSQHYK PEWPALSGLV AQAQAQAQVA PSLLERLQAT LSLPFAPSPQ
310 320 330 340 350
EGGVLDHLVT ATTSLASPFV TTACHTLCPD HPPSLGTRSK SVPELLGTAP
360 370 380 390 400
PPPLVPQSPP GSPQRSPWVF VPYQSPQGIL SKCLQWLQPR DSTSPRPQVP
410 420 430 440 450
KILLSKASSS SHQCQPKPSP SGHQSLALPL WRYQELRIEK RKQEEEARMA

QK
Note: No experimental confirmation available.
Length:452
Mass (Da):49,403
Last modified:December 20, 2017 - v4
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i0367E5EC638339BE
GO
Isoform 1 (identifier: Q7Z3H0-1) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-135: Missing.
     213-213: C → CECVATLLMAG
     347-452: GTAPPPPLVP...QEEEARMAQK → VPAEAQSFRT...EDGIGQAGNR

Show »
Length:272
Mass (Da):29,011
Checksum:i9A6C44A3D9FDA808
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F8VTQ6F8VTQ6_HUMAN
Photoreceptor ankyrin repeat protei...
ANKRD33
136Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAQ07991 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated
The sequence AAQ07992 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti303G → S in CAD97893 (PubMed:17974005).Curated1
Sequence conflicti303G → S in CAE45798 (PubMed:17974005).Curated1
Isoform 1 (identifier: Q7Z3H0-1)
Sequence conflicti262G → E in CAD97893 (PubMed:17974005).1
Sequence conflicti262G → E in CAE45798 (PubMed:17974005).1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_059121140Y → F. Corresponds to variant dbSNP:rs697636Ensembl.1
Natural variantiVAR_059122257Q → R1 PublicationCorresponds to variant dbSNP:rs34494292Ensembl.1
Natural variantiVAR_059123313T → N. Corresponds to variant dbSNP:rs12368048Ensembl.1
Isoform 1 (identifier: Q7Z3H0-1)
Natural varianti261V → I. Corresponds to variant dbSNP:rs3180417Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0592651 – 135Missing in isoform 1. 1 Publication1 PublicationAdd BLAST135
Alternative sequenceiVSP_059266213C → CECVATLLMAG in isoform 1. 1 Publication1 Publication1
Alternative sequenceiVSP_059267347 – 452GTAPP…RMAQK → VPAEAQSFRTPKSGPSSLAI PGAQDREEETGGGGQNGTEV GEDGIGQAGNR in isoform 1. 1 PublicationAdd BLAST106

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK125517 mRNA Translation: BAC86190.1
BX537908 mRNA Translation: CAD97893.1
BX640656 mRNA Translation: CAE45798.1
AC025259 Genomic DNA No translation available.
BC121153 mRNA Translation: AAI21154.1
AF517112 mRNA Translation: AAQ07991.1 Different initiation.
AF517113 mRNA Translation: AAQ07992.1 Different initiation.
AF517114 mRNA Translation: AAQ07993.1
AF517115 mRNA Translation: AAQ07994.1
AF517118 mRNA Translation: AAQ07996.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS44892.1 [Q7Z3H0-1]
CCDS8815.1 [Q7Z3H0-2]

NCBI Reference Sequences

More...
RefSeqi
NP_001123487.1, NM_001130015.1 [Q7Z3H0-1]
NP_001291388.1, NM_001304459.1
NP_872414.3, NM_182608.3 [Q7Z3H0-2]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000301190; ENSP00000301190; ENSG00000167612 [Q7Z3H0-2]
ENST00000340970; ENSP00000344690; ENSG00000167612 [Q7Z3H0-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
341405

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:341405

UCSC genome browser

More...
UCSCi
uc001rzd.4 human [Q7Z3H0-2]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK125517 mRNA Translation: BAC86190.1
BX537908 mRNA Translation: CAD97893.1
BX640656 mRNA Translation: CAE45798.1
AC025259 Genomic DNA No translation available.
BC121153 mRNA Translation: AAI21154.1
AF517112 mRNA Translation: AAQ07991.1 Different initiation.
AF517113 mRNA Translation: AAQ07992.1 Different initiation.
AF517114 mRNA Translation: AAQ07993.1
AF517115 mRNA Translation: AAQ07994.1
AF517118 mRNA Translation: AAQ07996.1
CCDSiCCDS44892.1 [Q7Z3H0-1]
CCDS8815.1 [Q7Z3H0-2]
RefSeqiNP_001123487.1, NM_001130015.1 [Q7Z3H0-1]
NP_001291388.1, NM_001304459.1
NP_872414.3, NM_182608.3 [Q7Z3H0-2]

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGridi131136, 4 interactors
IntActiQ7Z3H0, 11 interactors
STRINGi9606.ENSP00000301190

Polymorphism and mutation databases

BioMutaiANKRD33
DMDMi296439441

Proteomic databases

PaxDbiQ7Z3H0
PeptideAtlasiQ7Z3H0
PRIDEiQ7Z3H0
ProteomicsDBi69047
69048 [Q7Z3H0-2]

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000301190; ENSP00000301190; ENSG00000167612 [Q7Z3H0-2]
ENST00000340970; ENSP00000344690; ENSG00000167612 [Q7Z3H0-1]
GeneIDi341405
KEGGihsa:341405
UCSCiuc001rzd.4 human [Q7Z3H0-2]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
341405

GeneCards: human genes, protein and diseases

More...
GeneCardsi
ANKRD33
HGNCiHGNC:13788 ANKRD33
HPAiHPA040013
HPA058753
neXtProtiNX_Q7Z3H0
OpenTargetsiENSG00000167612
PharmGKBiPA25508

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410IG0V Eukaryota
ENOG410YB42 LUCA
GeneTreeiENSGT00500000044852
InParanoidiQ7Z3H0
OMAiCPQWLQP
OrthoDBi1045586at2759
PhylomeDBiQ7Z3H0
TreeFamiTF332022

Miscellaneous databases

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
341405

Protein Ontology

More...
PROi
PR:Q7Z3H0

Gene expression databases

BgeeiENSG00000167612 Expressed in 35 organ(s), highest expression level in placenta
ExpressionAtlasiQ7Z3H0 baseline and differential
GenevisibleiQ7Z3H0 HS

Family and domain databases

CDDicd00204 ANK, 1 hit
Gene3Di1.25.40.20, 1 hit
InterProiView protein in InterPro
IPR002110 Ankyrin_rpt
IPR020683 Ankyrin_rpt-contain_dom
IPR036770 Ankyrin_rpt-contain_sf
PfamiView protein in Pfam
PF12796 Ank_2, 1 hit
SMARTiView protein in SMART
SM00248 ANK, 4 hits
SUPFAMiSSF48403 SSF48403, 1 hit
PROSITEiView protein in PROSITE
PS50297 ANK_REP_REGION, 1 hit
PS50088 ANK_REPEAT, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiPANKY_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q7Z3H0
Secondary accession number(s): Q0VAA7
, Q5K619, Q5K621, Q5K622, Q5K623, Q5K624, Q6ZUN0
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: December 20, 2017
Last modified: May 8, 2019
This is version 117 of the entry and version 4 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  2. Human chromosome 12
    Human chromosome 12: entries, gene names and cross-references to MIM
  3. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
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