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Protein

MAM domain-containing protein 2

Gene

MAMDC2

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
MAM domain-containing protein 2
Alternative name(s):
MAM domain-containing proteoglycan
Short name:
Mamcan
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:MAMDC2
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 9

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000165072.9

Human Gene Nomenclature Database

More...
HGNCi
HGNC:23673 MAMDC2

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
612879 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q7Z304

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Extracellular matrix, Secreted

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
256691

Open Targets

More...
OpenTargetsi
ENSG00000165072

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134944739

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
MAMDC2

Domain mapping of disease mutations (DMDM)

More...
DMDMi
311033426

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 18Sequence analysisAdd BLAST18
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000001486219 – 686MAM domain-containing protein 2Add BLAST668

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi134N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi329N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi524N-linked (GlcNAc...) asparagineSequence analysis1

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

O-glycosylated.By similarity

Keywords - PTMi

Glycoprotein

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q7Z304

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q7Z304

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q7Z304

PeptideAtlas

More...
PeptideAtlasi
Q7Z304

PRoteomics IDEntifications database

More...
PRIDEi
Q7Z304

ProteomicsDB human proteome resource

More...
ProteomicsDBi
68993
68994 [Q7Z304-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q7Z304

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q7Z304

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000165072 Expressed in 181 organ(s), highest expression level in layer of synovial tissue

CleanEx database of gene expression profiles

More...
CleanExi
HS_MAMDC2

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q7Z304 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA021814
HPA022249

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
129176, 5 interactors

Protein interaction database and analysis system

More...
IntActi
Q7Z304, 2 interactors

Molecular INTeraction database

More...
MINTi
Q7Z304

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000366387

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
Q7Z304

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q7Z304

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini24 – 169MAM 1PROSITE-ProRule annotationAdd BLAST146
Domaini168 – 329MAM 2PROSITE-ProRule annotationAdd BLAST162
Domaini340 – 498MAM 3PROSITE-ProRule annotationAdd BLAST159
Domaini507 – 666MAM 4PROSITE-ProRule annotationAdd BLAST160

Keywords - Domaini

Repeat, Signal

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IF4R Eukaryota
ENOG410ZUUQ LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000156117

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000247053

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG017920

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q7Z304

Identification of Orthologs from Complete Genome Data

More...
OMAi
PGECTFE

Database of Orthologous Groups

More...
OrthoDBi
270113at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q7Z304

TreeFam database of animal gene trees

More...
TreeFami
TF330345

Family and domain databases

Conserved Domains Database

More...
CDDi
cd06263 MAM, 4 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR013320 ConA-like_dom_sf
IPR000998 MAM_dom

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00629 MAM, 4 hits

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00020 MAMDOMAIN

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00137 MAM, 4 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF49899 SSF49899, 4 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00740 MAM_1, 2 hits
PS50060 MAM_2, 4 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform 1 (identifier: Q7Z304-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MLLRGVLLAL QALQLAGALD LPAGSCAFEE STCGFDSVLA SLPWILNEEG
60 70 80 90 100
HYIYVDTSFG KQGEKAVLLS PDLQAEEWSC LRLVYQITTS SESLSDPSQL
110 120 130 140 150
NLYMRFEDES FDRLLWSAKE PSDSWLIASL DLQNSSKKFK ILIEGVLGQG
160 170 180 190 200
NTASIALFEI KMTTGYCIEC DFEENHLCGF VNRWNPNVNW FVGGGSIRNV
210 220 230 240 250
HSILPQDHTF KSELGHYMYV DSVYVKHFQE VAQLISPLTT APMAGCLSFY
260 270 280 290 300
YQIQQGNDNV FSLYTRDVAG LYEEIWKADR PGNAAWNLAE VEFSAPYPME
310 320 330 340 350
VIFEVAFNGP KGGYVALDDI SFSPVHCQNQ TELLFSAVEA SCNFEQDLCN
360 370 380 390 400
FYQDKEGPGW TRVKVKPNMY RAGDHTTGLG YYLLANTKFT SQPGYIGRLY
410 420 430 440 450
GPSLPGNLQY CLRFHYAIYG FLKMSDTLAV YIFEENHVVQ EKIWSVLESP
460 470 480 490 500
RGVWMQAEIT FKKPMPTKVV FMSLCKSFWD CGLVALDDIT IQLGSCSSSE
510 520 530 540 550
KLPPPPGECT FEQDECTFTQ EKRNRSSWHR RRGETPTSYT GPKGDHTTGV
560 570 580 590 600
GYYMYIEASH MVYGQKARLL SRPLRGVSGK HCLTFFYHMY GGGTGLLSVY
610 620 630 640 650
LKKEEDSEES LLWRRRGEQS ISWLRALIEY SCERQHQIIF EAIRGVSIRS
660 670 680
DIAIDDVKFQ AGPCGEMEDT TQQSSGYSED LNEIEY
Length:686
Mass (Da):77,556
Last modified:November 2, 2010 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iFA343D1521A2963D
GO
Isoform 2 (identifier: Q7Z304-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-553: Missing.

Note: No experimental confirmation available.
Show »
Length:133
Mass (Da):15,293
Checksum:i664306D48D3C5213
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0G2JQ91A0A0G2JQ91_HUMAN
MAM domain-containing protein 2
MAMDC2
549Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_028080294S → N1 PublicationCorresponds to variant dbSNP:rs1998972Ensembl.1
Natural variantiVAR_061318646V → A. Corresponds to variant dbSNP:rs35534839Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting. The information stored in this subsection is used to automatically construct alternative protein sequence(s) for display.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0098341 – 553Missing in isoform 2. 1 PublicationAdd BLAST553

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
BX538309 mRNA Translation: CAD98089.1
AL158153 Genomic DNA No translation available.
AL392044 Genomic DNA No translation available.
BC015417 mRNA Translation: AAH15417.1
BC016383 mRNA Translation: AAH16383.1
BC063634 mRNA Translation: AAH63634.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS6631.1 [Q7Z304-1]

NCBI Reference Sequences

More...
RefSeqi
NP_694999.3, NM_153267.4 [Q7Z304-1]

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.547172
Hs.666569

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000377182; ENSP00000366387; ENSG00000165072 [Q7Z304-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
256691

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:256691

UCSC genome browser

More...
UCSCi
uc004ahm.3 human [Q7Z304-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX538309 mRNA Translation: CAD98089.1
AL158153 Genomic DNA No translation available.
AL392044 Genomic DNA No translation available.
BC015417 mRNA Translation: AAH15417.1
BC016383 mRNA Translation: AAH16383.1
BC063634 mRNA Translation: AAH63634.1
CCDSiCCDS6631.1 [Q7Z304-1]
RefSeqiNP_694999.3, NM_153267.4 [Q7Z304-1]
UniGeneiHs.547172
Hs.666569

3D structure databases

ProteinModelPortaliQ7Z304
SMRiQ7Z304
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi129176, 5 interactors
IntActiQ7Z304, 2 interactors
MINTiQ7Z304
STRINGi9606.ENSP00000366387

PTM databases

iPTMnetiQ7Z304
PhosphoSitePlusiQ7Z304

Polymorphism and mutation databases

BioMutaiMAMDC2
DMDMi311033426

Proteomic databases

jPOSTiQ7Z304
MaxQBiQ7Z304
PaxDbiQ7Z304
PeptideAtlasiQ7Z304
PRIDEiQ7Z304
ProteomicsDBi68993
68994 [Q7Z304-2]

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
256691
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000377182; ENSP00000366387; ENSG00000165072 [Q7Z304-1]
GeneIDi256691
KEGGihsa:256691
UCSCiuc004ahm.3 human [Q7Z304-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
256691
DisGeNETi256691
EuPathDBiHostDB:ENSG00000165072.9

GeneCards: human genes, protein and diseases

More...
GeneCardsi
MAMDC2

H-Invitational Database, human transcriptome db

More...
H-InvDBi
HIX0017975
HGNCiHGNC:23673 MAMDC2
HPAiHPA021814
HPA022249
MIMi612879 gene
neXtProtiNX_Q7Z304
OpenTargetsiENSG00000165072
PharmGKBiPA134944739

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410IF4R Eukaryota
ENOG410ZUUQ LUCA
GeneTreeiENSGT00940000156117
HOGENOMiHOG000247053
HOVERGENiHBG017920
InParanoidiQ7Z304
OMAiPGECTFE
OrthoDBi270113at2759
PhylomeDBiQ7Z304
TreeFamiTF330345

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
MAMDC2 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
256691

Protein Ontology

More...
PROi
PR:Q7Z304

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000165072 Expressed in 181 organ(s), highest expression level in layer of synovial tissue
CleanExiHS_MAMDC2
GenevisibleiQ7Z304 HS

Family and domain databases

CDDicd06263 MAM, 4 hits
InterProiView protein in InterPro
IPR013320 ConA-like_dom_sf
IPR000998 MAM_dom
PfamiView protein in Pfam
PF00629 MAM, 4 hits
PRINTSiPR00020 MAMDOMAIN
SMARTiView protein in SMART
SM00137 MAM, 4 hits
SUPFAMiSSF49899 SSF49899, 4 hits
PROSITEiView protein in PROSITE
PS00740 MAM_1, 2 hits
PS50060 MAM_2, 4 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiMAMC2_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q7Z304
Secondary accession number(s): Q5VW47, Q8WX43, Q96BM4
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 13, 2004
Last sequence update: November 2, 2010
Last modified: January 16, 2019
This is version 127 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  2. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  3. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  4. Human chromosome 9
    Human chromosome 9: entries, gene names and cross-references to MIM
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