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Protein

Neurotoxin BmP08

Gene
N/A
Organism
Mesobuthus martensii (Manchurian scorpion) (Buthus martensii)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Miscellaneous

Does not show any effect on Na+, Ca2+ currents, nor on voltage-gated and calcium-activated potassium channels.

Names & Taxonomyi

Protein namesi
Recommended name:
Neurotoxin BmP08
Alternative name(s):
Short-chain peptide BmKX
OrganismiMesobuthus martensii (Manchurian scorpion) (Buthus martensii)
Taxonomic identifieri34649 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaChelicerataArachnidaScorpionesButhidaButhoideaButhidaeMesobuthus

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 231 PublicationAdd BLAST23
ChainiPRO_000003533824 – 54Neurotoxin BmP08Add BLAST31

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi30 ↔ 45
Disulfide bondi36 ↔ 50
Disulfide bondi39 ↔ 53

Keywords - PTMi

Disulfide bond

Expressioni

Tissue specificityi

Expressed by the venom gland.

Structurei

Secondary structure

155
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

ProteinModelPortaliQ7Z0H4
SMRiQ7Z0H4
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ7Z0H4

Family & Domainsi

Keywords - Domaini

Signal

Family and domain databases

InterProiView protein in InterPro
IPR036574 Scorpion_toxin-like_sf
SUPFAMiSSF57095 SSF57095, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q7Z0H4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKIFFAVLVI LVLFSMLIWT AYGTPYPVNC KTDRDCVMCG LGISCKNGYC

QGCTR
Length:55
Mass (Da):6,145
Last modified:October 1, 2003 - v1
Checksum:i8B30D90904D6A39C
GO

Mass spectrometryi

Molecular mass is 3326 Da from positions 24 - 54. Determined by ESI. 1 Publication

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY125328 mRNA Translation: AAM91031.1
AY147404 Genomic DNA Translation: AAN39841.1

Similar proteinsi

Entry informationi

Entry nameiSCKI_MESMA
AccessioniPrimary (citable) accession number: Q7Z0H4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 24, 2004
Last sequence update: October 1, 2003
Last modified: October 25, 2017
This is version 57 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

3D-structure, Direct protein sequencing
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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