UniProtKB - Q7YRC1 (AIP_BOVIN)
Protein
AH receptor-interacting protein
Gene
AIP
Organism
Bos taurus (Bovine)
Status
Functioni
May play a positive role in AHR-mediated (aromatic hydrocarbon receptor) signaling, possibly by influencing its receptivity for ligand and/or its nuclear targeting.By similarity
GO - Molecular functioni
- peptidyl-prolyl cis-trans isomerase activity Source: InterPro
- transcription coregulator activity Source: AgBase
GO - Biological processi
- xenobiotic metabolic process Source: AgBase
Names & Taxonomyi
Protein namesi | Recommended name: AH receptor-interacting proteinShort name: AIP Alternative name(s): Aryl-hydrocarbon receptor-interacting protein |
Gene namesi | Name:AIP |
Organismi | Bos taurus (Bovine) |
Taxonomic identifieri | 9913 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Laurasiatheria › Artiodactyla › Ruminantia › Pecora › Bovidae › Bovinae › Bos |
Proteomesi |
|
Subcellular locationi
Keywords - Cellular componenti
CytoplasmPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000075337 | 1 – 330 | AH receptor-interacting proteinAdd BLAST | 330 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 43 | PhosphoserineBy similarity | 1 |
Keywords - PTMi
PhosphoproteinProteomic databases
PaxDbi | Q7YRC1 |
PRIDEi | Q7YRC1 |
Interactioni
Subunit structurei
Interacts with RET in the pituitary gland; this interaction prevents the formation of the AIP-survivin complex.
Protein-protein interaction databases
STRINGi | 9913.ENSBTAP00000013841 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 54 – 146 | PPIase FKBP-typePROSITE-ProRule annotationAdd BLAST | 93 | |
Repeati | 179 – 212 | TPR 1Sequence analysisAdd BLAST | 34 | |
Repeati | 231 – 264 | TPR 2By similarityAdd BLAST | 34 | |
Repeati | 265 – 298 | TPR 3Sequence analysisAdd BLAST | 34 |
Keywords - Domaini
Repeat, TPR repeatPhylogenomic databases
eggNOGi | KOG0545, Eukaryota |
InParanoidi | Q7YRC1 |
Family and domain databases
Gene3Di | 1.25.40.10, 1 hit |
InterProi | View protein in InterPro IPR031208, AIP IPR039663, AIP/AIPL1 IPR001179, PPIase_FKBP_dom IPR013026, TPR-contain_dom IPR011990, TPR-like_helical_dom_sf IPR019734, TPR_repeat |
PANTHERi | PTHR11242, PTHR11242, 1 hit PTHR11242:SF3, PTHR11242:SF3, 1 hit |
Pfami | View protein in Pfam PF00254, FKBP_C, 1 hit |
SUPFAMi | SSF48452, SSF48452, 1 hit |
PROSITEi | View protein in PROSITE PS50059, FKBP_PPIASE, 1 hit PS50005, TPR, 1 hit PS50293, TPR_REGION, 1 hit |
i Sequence
Sequence statusi: Complete.
Q7YRC1-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MADIIARLRE DGIQKRVIQE GRGALPDFQD GTKATFHYRT LCSDEEGAVL
60 70 80 90 100
DDSRVRGKPM ELIIGKKFKL PVWETIVRTM REGEIAQFCC DXKHVVLYPL
110 120 130 140 150
VAKSLRNIAA GKDPLEGQRH CCGIAQMHXH SSLGHADLDA LQQNPQPLIF
160 170 180 190 200
DIEMLKVENP GTYQQDPWAM TDEEKAKAVP VIHQEGNRLY REGHVKEAAA
210 220 230 240 250
KYYDAIACLK NLQMKEQPGS PDWIQLDQQI TPLLLNYCQC KLVAEEYYEV
260 270 280 290 300
LDHCSSILNK YDDNVKAYFK RGKAHAAVWN AQQAQDDFAK VLQLDPAMAP
310 320 330
VVSRELRALE ARIRQKDEED KARFRGIFSH
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AY339893 mRNA Translation: AAQ17068.1 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AY339893 mRNA Translation: AAQ17068.1 |
3D structure databases
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 9913.ENSBTAP00000013841 |
Proteomic databases
PaxDbi | Q7YRC1 |
PRIDEi | Q7YRC1 |
Phylogenomic databases
eggNOGi | KOG0545, Eukaryota |
InParanoidi | Q7YRC1 |
Family and domain databases
Gene3Di | 1.25.40.10, 1 hit |
InterProi | View protein in InterPro IPR031208, AIP IPR039663, AIP/AIPL1 IPR001179, PPIase_FKBP_dom IPR013026, TPR-contain_dom IPR011990, TPR-like_helical_dom_sf IPR019734, TPR_repeat |
PANTHERi | PTHR11242, PTHR11242, 1 hit PTHR11242:SF3, PTHR11242:SF3, 1 hit |
Pfami | View protein in Pfam PF00254, FKBP_C, 1 hit |
SUPFAMi | SSF48452, SSF48452, 1 hit |
PROSITEi | View protein in PROSITE PS50059, FKBP_PPIASE, 1 hit PS50005, TPR, 1 hit PS50293, TPR_REGION, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | AIP_BOVIN | |
Accessioni | Q7YRC1Primary (citable) accession number: Q7YRC1 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | May 10, 2005 |
Last sequence update: | October 1, 2003 | |
Last modified: | August 12, 2020 | |
This is version 89 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program |