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Protein

Transcription factor 19

Gene

TCF19

Organism
Pan troglodytes (Chimpanzee)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Potential trans-activating factor that could play an important role in the transcription of genes required for the later stages of cell cycle progression.By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri296 – 339PHD-typeAdd BLAST44

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Transcription factor 19
Short name:
TCF-19
Alternative name(s):
Transcription factor SC1
Gene namesi
Name:TCF19
Synonyms:SC1
OrganismiPan troglodytes (Chimpanzee)
Taxonomic identifieri9598 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePan
Proteomesi
  • UP000002277 Componenti: Chromosome 6

Organism-specific databases

VGNCiVGNC:12712 TCF19

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000593281 – 345Transcription factor 19Add BLAST345

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei78PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiQ7YR48

Expressioni

Gene expression databases

BgeeiENSPTRG00000017952 Expressed in 6 organ(s), highest expression level in liver

Interactioni

Protein-protein interaction databases

STRINGi9598.ENSPTRP00000043439

Structurei

3D structure databases

ProteinModelPortaliQ7YR48
SMRiQ7YR48
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini31 – 88FHAPROSITE-ProRule annotationAdd BLAST58

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri296 – 339PHD-typeAdd BLAST44

Keywords - Domaini

Zinc-finger

Phylogenomic databases

eggNOGiENOG410IXZZ Eukaryota
ENOG4111J5W LUCA
GeneTreeiENSGT00390000015391
HOGENOMiHOG000261618
HOVERGENiHBG054343
InParanoidiQ7YR48
OMAiEADFRCP
OrthoDBiEOG091G05D2
TreeFamiTF334697

Family and domain databases

CDDicd00060 FHA, 1 hit
cd15609 PHD_TCF19, 1 hit
Gene3Di3.30.40.10, 1 hit
InterProiView protein in InterPro
IPR000253 FHA_dom
IPR008984 SMAD_FHA_dom_sf
IPR039095 TCF19_PHD
IPR019786 Zinc_finger_PHD-type_CS
IPR011011 Znf_FYVE_PHD
IPR001965 Znf_PHD
IPR013083 Znf_RING/FYVE/PHD
PfamiView protein in Pfam
PF00498 FHA, 1 hit
SMARTiView protein in SMART
SM00240 FHA, 1 hit
SM00249 PHD, 1 hit
SUPFAMiSSF49879 SSF49879, 1 hit
SSF57903 SSF57903, 1 hit
PROSITEiView protein in PROSITE
PS50006 FHA_DOMAIN, 1 hit
PS01359 ZF_PHD_1, 1 hit

Sequencei

Sequence statusi: Complete.

Q7YR48-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLPCFQLLRI GGGRGGDLYT FHPPAGAGCT YRLGHRADLC DVALRPQQEP
60 70 80 90 100
GLISGIHAEL HAEPRGDDWR VSLEDHSSQG TLVNNVRLPR GHRLELSDGD
110 120 130 140 150
LLTFGPEGPP GTSPSEFYFM FQQVRVKPQD FAAITIPRSR GEARVGAGFR
160 170 180 190 200
PMLPSQGAPQ RPLSTLSPAP KATLILNSIG SLSKLRPQPL TFSPSWGGPK
210 220 230 240 250
SLPVPAPPGE VGTTPSAPPQ RNRRKSVHRV LAELDDESEP PENPPPVLME
260 270 280 290 300
RRKKLRVDKA PLTPTGNRRG RPRKYPVSAP VAPPAVGGGE PCAAPCCCLP
310 320 330 340
QEETVAWVQC DGCDVWFHVA CVGCSIQAAR EADFRCPGCR AGIQT
Length:345
Mass (Da):37,144
Last modified:October 1, 2003 - v1
Checksum:i45D666461FAFB9F8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000041 Genomic DNA Translation: BAC78166.1
AB210197 Genomic DNA Translation: BAE92815.1
AB210198 Genomic DNA Translation: BAE92817.1
RefSeqiNP_001129081.1, NM_001135609.1
XP_009449065.1, XM_009450790.2
XP_009449066.1, XM_009450791.2
UniGeneiPtr.6547

Genome annotation databases

EnsembliENSPTRT00000045450; ENSPTRP00000043439; ENSPTRG00000017952
GeneIDi100190896
KEGGiptr:100190896

Similar proteinsi

Entry informationi

Entry nameiTCF19_PANTR
AccessioniPrimary (citable) accession number: Q7YR48
Secondary accession number(s): Q1XHV3, Q1XHV5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 16, 2004
Last sequence update: October 1, 2003
Last modified: September 12, 2018
This is version 89 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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