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UniProtKB - Q7XM31 (RDR2_ORYSJ)
Protein
Probable RNA-dependent RNA polymerase 2
Gene
RDR2
Organism
Oryza sativa subsp. japonica (Rice)
Status
Functioni
Probably involved in the RNA silencing pathway and required for the generation of small interfering RNAs (siRNAs).
By similarityCatalytic activityi
- EC:2.7.7.48
GO - Molecular functioni
- RNA binding Source: UniProtKB-KW
- RNA-directed 5'-3' RNA polymerase activity Source: GO_Central
GO - Biological processi
- production of siRNA involved in gene silencing by small RNA Source: GO_Central
- production of siRNA involved in RNA interference Source: GO_Central
Keywordsi
Molecular function | Nucleotidyltransferase, RNA-binding, RNA-directed RNA polymerase, Transferase |
Biological process | RNA-mediated gene silencing |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Name:RDR2 Ordered Locus Names:Os04g0465700, LOC_Os04g39160 ORF Names:OSJNBb0048E02.13 |
Organismi | Oryza sativa subsp. japonica (Rice) |
Taxonomic identifieri | 39947 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › Liliopsida › Poales › Poaceae › BOP clade › Oryzoideae › Oryzeae › Oryzinae › Oryza › Oryza sativa |
Proteomesi |
|
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000378446 | 1 – 1136 | Probable RNA-dependent RNA polymerase 2Add BLAST | 1136 |
Proteomic databases
PaxDbi | Q7XM31 |
PRIDEi | Q7XM31 |
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 965 – 989 | DisorderedSequence analysisAdd BLAST | 25 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 967 – 981 | Polar residuesSequence analysisAdd BLAST | 15 |
Sequence similaritiesi
Belongs to the RdRP family.Curated
Phylogenomic databases
eggNOGi | KOG0988, Eukaryota |
HOGENOMi | CLU_001366_1_1_1 |
InParanoidi | Q7XM31 |
OrthoDBi | 63910at2759 |
Family and domain databases
InterProi | View protein in InterPro IPR007855, RNA-dep_RNA_pol_euk-typ |
PANTHERi | PTHR23079, PTHR23079, 1 hit |
Pfami | View protein in Pfam PF05183, RdRP, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All
Q7XM31-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MPTAAAAATA SLRVSNIPPS AVAAELLAFF DSAVAVAGGA FACEIAAAHR
60 70 80 90 100
GWLSRGHGTV QFGSAAAAAA AAGLASSGRL PRFLGALLSV SPSPVDLLPR
110 120 130 140 150
ASDLSLRAAG AGLVVGDRVA ERVFEAADAW DGVRAEVIPG KRRVDLYLEH
160 170 180 190 200
DSQRYKLEVL FEDMKDCLGC TLDGMGAILL QLNYAPRIHT AISGPAVNSR
210 220 230 240 250
FMDDRFHACK EDAKFSWVRA LDFTPNYSFG RCSTLVLKLG KSALVSDILK
260 270 280 290 300
SLPFSGNLGE LTMNSMDGVG ASSNVVPLVH CPRDYSVPYE VLFRLNSLMH
310 320 330 340 350
MGKIVAKHVN ADLFKALQEL PVDVSRRIFE KMHKLESTCY GPLQFIQQEA
360 370 380 390 400
YSMKRSHNVL LSNEGEGEGE RKLMKCYRVN ITPSKIFCFG PEEEVTNYVV
410 420 430 440 450
KHHSAYASDF VRVTFVDEDW SKLSSNAISA RIEQGFFSKP FKTGLYYRIL
460 470 480 490 500
SILKKGFSIG PKNFEFLAFS ASQLRGNSVW MFASNASLNA GGIRRWMGHF
510 520 530 540 550
ENIRSVSKCA ARMGQLFSSS RQTFEVLRWD VEVIPDIEIT TDGSKYIFSD
560 570 580 590 600
GIGKISLRFA KRVAHHVGLD PTNLPSAFQI RYGGYKGVIA IDPMSSIDLS
610 620 630 640 650
LRPSMKKFES ESRMLNITSW SKSQPCYVNR EIISLLSTLG IRDEIFVAMQ
660 670 680 690 700
QDEMRETEEM LTNKEVALSV LGKLGGSETK TAVKMLLQGY EPSSEPYLSM
710 720 730 740 750
ILKAHQENRL TDIRTRCKIH VPKGRVLIGC LDETGVLEYG QVYIRITKNS
760 770 780 790 800
KEQKDSNQSY FYNDDGKTAT VVGKVAITKN PCLHPGDIRV LEAIYDPDLV
810 820 830 840 850
GMVDCLVFPQ RGERPHPNEC SGGDLDGDLY FITWDDKLIP EKVDTPMDYT
860 870 880 890 900
ATRPRIMDHV VTLEEIQKHF VDYMINDSLG AISTAHLIHA DRSPLKARSP
910 920 930 940 950
ECLQLATLHS MAVDFAKTGA PAEMPRTLRP REYPDFMERW EKPMYISNGV
960 970 980 990 1000
LGKLYRSAMG HMEKSGDSGA LSSSSAQPSP TYDPDLEVPG SDEFLQAAEE
1010 1020 1030 1040 1050
YYELYEEKLT TLMNYYRAEL EDEILTGNIR NKMLYLKRDN KRYFEMKDRI
1060 1070 1080 1090 1100
VAAVDALHRE ARGWLLSSRK EEDASRMASA WYRVTYHPDR RRGKRFWSFP
1110 1120 1130
WIACDNLLAI KASSQLRRRR QKDDDSTAVV QMDCSA
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketA0A0P0WB44 | A0A0P0WB44_ORYSJ | RNA-dependent RNA polymerase | Os04g0465700, OSNPB_040465700 | 377 | Annotation score: |
Sequence cautioni
The sequence BAF14941 differs from that shown. Reason: Erroneous gene model prediction.Curated
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 993 | E → G in AK064379 (PubMed:12869764).Curated | 1 | |
Sequence conflicti | 1052 | A → V in AK064379 (PubMed:12869764).Curated | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL606653 Genomic DNA Translation: CAE04828.1 AP008210 Genomic DNA Translation: BAF14941.1 Sequence problems. AP014960 Genomic DNA No translation available. AK064379 mRNA No translation available. |
RefSeqi | XP_015636884.1, XM_015781398.1 |
Genome annotation databases
GeneIDi | 4336092 |
KEGGi | osa:4336092 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL606653 Genomic DNA Translation: CAE04828.1 AP008210 Genomic DNA Translation: BAF14941.1 Sequence problems. AP014960 Genomic DNA No translation available. AK064379 mRNA No translation available. |
RefSeqi | XP_015636884.1, XM_015781398.1 |
3D structure databases
AlphaFoldDBi | Q7XM31 |
SMRi | Q7XM31 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 4530.OS04T0465700-01 |
Proteomic databases
PaxDbi | Q7XM31 |
PRIDEi | Q7XM31 |
Genome annotation databases
GeneIDi | 4336092 |
KEGGi | osa:4336092 |
Phylogenomic databases
eggNOGi | KOG0988, Eukaryota |
HOGENOMi | CLU_001366_1_1_1 |
InParanoidi | Q7XM31 |
OrthoDBi | 63910at2759 |
Gene expression databases
Genevisiblei | Q7XM31, OS |
Family and domain databases
InterProi | View protein in InterPro IPR007855, RNA-dep_RNA_pol_euk-typ |
PANTHERi | PTHR23079, PTHR23079, 1 hit |
Pfami | View protein in Pfam PF05183, RdRP, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | RDR2_ORYSJ | |
Accessioni | Q7XM31Primary (citable) accession number: Q7XM31 Secondary accession number(s): Q0JCJ6 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | July 7, 2009 |
Last sequence update: | October 1, 2003 | |
Last modified: | May 25, 2022 | |
This is version 96 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Oryza sativa (rice)
Index of Oryza sativa entries and their corresponding gene designations - SIMILARITY comments
Index of protein domains and families