UniProtKB - Q7XJ98 (MUR3_ARATH)
Protein
Xyloglucan galactosyltransferase MUR3
Gene
MUR3
Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Functioni
Involved in the attachment of the Gal residue on the third xylosyl unit within the XXXG core structure of xyloglucan, the principal glycan that interlaces the cellulose microfibrils in plant cell wall (PubMed:12837954). Associates with other xyloglucan-synthesizing enzymes to form multiprotein complexes for xyloglucan synthesis in the Golgi (PubMed:25392066). Interacts with actin and is required for the proper endomembrane organization and for the cell elongation. Not involved in the trafficking from the endoplasmic reticulum to the vacuoles (PubMed:15863516). Involved in salt stress tolerance. Participates in the control of the expression of genes encoding for proteins involved in reactive oxygen species (ROS) detoxification under salt stress. May contribute to the maintenance of the proper organization of actin microfilaments during salt stress-induced ROS production (PubMed:23571490).4 Publications
GO - Molecular functioni
- transferase activity, transferring glycosyl groups Source: TAIR
GO - Biological processi
- endomembrane system organization Source: TAIR
- fucose biosynthetic process Source: TAIR
- protein glycosylation Source: InterPro
- salicylic acid mediated signaling pathway Source: TAIR
- unidimensional cell growth Source: TAIR
- xyloglucan biosynthetic process Source: TAIR
Keywordsi
Molecular function | Glycosyltransferase, Transferase |
Biological process | Stress response |
Enzyme and pathway databases
BioCyci | ARA:AT2G20370-MONOMER MetaCyc:AT2G20370-MONOMER |
Protein family/group databases
CAZyi | GT47, Glycosyltransferase Family 47 |
Names & Taxonomyi
Protein namesi | Recommended name: Xyloglucan galactosyltransferase MUR3Curated (EC:2.4.1.-Curated)Alternative name(s): Protein KATAMARI1 Publication Protein MURUS 31 Publication Short name: AtMUR31 Publication Protein SHORT ROOT IN SALT MEDIUM 31 Publication |
Gene namesi | Name:MUR31 Publication Synonyms:KAM11 Publication, RSA31 Publication Ordered Locus Names:At2g20370 ORF Names:F11A3.8 |
Organismi | Arabidopsis thaliana (Mouse-ear cress) |
Taxonomic identifieri | 3702 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › eudicotyledons › Gunneridae › Pentapetalae › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis |
Proteomesi |
|
Organism-specific databases
Araporti | AT2G20370 |
TAIRi | locus:2039002, AT2G20370 |
Subcellular locationi
Golgi apparatus
- Golgi stack membrane 1 Publication; Single-pass type II membrane protein 1 Publication
- Golgi apparatus membrane 1 Publication; Single-pass type II membrane protein 1 Publication
Endosome
- endosome Source: TAIR
Golgi apparatus
- Golgi apparatus Source: TAIR
- Golgi cisterna membrane Source: UniProtKB-SubCell
- Golgi trans cisterna Source: TAIR
- integral component of Golgi membrane Source: TAIR
- trans-Golgi network Source: TAIR
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 1 – 33 | Cytoplasmic1 PublicationAdd BLAST | 33 | |
Transmembranei | 34 – 54 | Helical; Signal-anchor for type II membrane proteinSequence analysisAdd BLAST | 21 | |
Topological domaini | 55 – 619 | Lumenal1 PublicationAdd BLAST | 565 |
Keywords - Cellular componenti
Golgi apparatus, MembranePathology & Biotechi
Disruption phenotypei
Stunted growth.2 Publications
Mutagenesis
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Mutagenesisi | 290 | A → V in mur3-2; altered xyloglucan, but normal endomembrane organization. 1 Publication | 1 | |
Mutagenesisi | 470 | S → L in mur3-1; altered xyloglucan, but normal endomembrane organization. In mur3-5 and cie1; stunted growth; when associated with I-539. 2 Publications | 1 | |
Mutagenesisi | 539 | T → I in mur3-5 and cie1; stunted growth; when associated with L-470. 1 Publication | 1 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000149667 | 1 – 619 | Xyloglucan galactosyltransferase MUR3Add BLAST | 619 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Glycosylationi | 116 | N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation | 1 | |
Glycosylationi | 146 | N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation | 1 | |
Glycosylationi | 231 | N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation | 1 | |
Glycosylationi | 257 | N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation | 1 | |
Glycosylationi | 319 | N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation | 1 | |
Glycosylationi | 465 | N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation | 1 | |
Glycosylationi | 482 | N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation | 1 |
Keywords - PTMi
GlycoproteinProteomic databases
PaxDbi | Q7XJ98 |
PRIDEi | Q7XJ98 |
ProteomicsDBi | 251380 |
PTM databases
SwissPalmi | Q7XJ98 |
Expressioni
Tissue specificityi
Ubiquitous.1 Publication
Inductioni
By salt stress.1 Publication
Gene expression databases
ExpressionAtlasi | Q7XJ98, baseline and differential |
Genevisiblei | Q7XJ98, AT |
Interactioni
Subunit structurei
Interacts with CSLC4 and FUT1.
1 PublicationProtein-protein interaction databases
BioGRIDi | 1909, 8 interactors |
STRINGi | 3702.AT2G20370.1 |
Family & Domainsi
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 85 – 124 | Pro-richAdd BLAST | 40 |
Domaini
The cytoplasmic N-terminal domain interacts with actin, while the lumenal C-terminal domain contributes to the activity of xyloglucan galactosyltransferase.1 Publication
Sequence similaritiesi
Belongs to the glycosyltransferase 47 family.Curated
Keywords - Domaini
Signal-anchor, Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | KOG1021, Eukaryota |
HOGENOMi | CLU_012659_2_0_1 |
InParanoidi | Q7XJ98 |
OMAi | MNTATEK |
OrthoDBi | 789556at2759 |
PhylomeDBi | Q7XJ98 |
Family and domain databases
InterProi | View protein in InterPro IPR004263, Exostosin IPR040911, Exostosin_GT47 |
PANTHERi | PTHR11062, PTHR11062, 1 hit |
Pfami | View protein in Pfam PF03016, Exostosin, 1 hit |
i Sequence
Sequence statusi: Complete.
Q7XJ98-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MFPRVSMRRR SAEVSPTEPM EKGNGKNQTN RICLLVALSL FFWALLLYFH
60 70 80 90 100
FVVLGTSNID KQLQLQPSYA QSQPSSVSLR VDKFPIEPHA APSKPPPKEP
110 120 130 140 150
LVTIDKPILP PAPVANSSST FKPPRIVESG KKQEFSFIRA LKTVDNKSDP
160 170 180 190 200
CGGKYIYVHN LPSKFNEDML RDCKKLSLWT NMCKFTTNAG LGPPLENVEG
210 220 230 240 250
VFSDEGWYAT NQFAVDVIFS NRMKQYKCLT NDSSLAAAIF VPFYAGFDIA
260 270 280 290 300
RYLWGYNISR RDAASLELVD WLMKRPEWDI MRGKDHFLVA GRITWDFRRL
310 320 330 340 350
SEEETDWGNK LLFLPAAKNM SMLVVESSPW NANDFGIPYP TYFHPAKDSE
360 370 380 390 400
VFEWQDRMRN LERKWLFSFA GAPRPDNPKS IRGQIIDQCR NSNVGKLLEC
410 420 430 440 450
DFGESKCHAP SSIMQMFQSS LFCLQPQGDS YTRRSAFDSM LAGCIPVFFH
460 470 480 490 500
PGSAYTQYTW HLPKNYTTYS VFIPEDDVRK RNISIEERLL QIPAKQVKIM
510 520 530 540 550
RENVINLIPR LIYADPRSEL ETQKDAFDVS VQAVIDKVTR LRKNMIEGRT
560 570 580 590 600
EYDYFVEENS WKYALLEEGQ REAGGHVWDP FFSKPKPGED GSSDGNGGTT
610
ISADAAKNSW KSEQRDKTQ
Sequence cautioni
The sequence AAD21751 differs from that shown. Reason: Erroneous gene model prediction.Curated
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 87 | E → G in BAE98519 (Ref. 6) Curated | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AY195743 Genomic DNA Translation: AAO39815.1 KJ138908 mRNA Translation: AHL38848.1 AC006569 Genomic DNA Translation: AAD21751.1 Sequence problems. CP002685 Genomic DNA Translation: AEC06999.1 BT023734 mRNA Translation: AAZ23926.1 AK226372 mRNA Translation: BAE98519.1 |
PIRi | D84588 |
RefSeqi | NP_179627.2, NM_127596.3 |
Genome annotation databases
EnsemblPlantsi | AT2G20370.1; AT2G20370.1; AT2G20370 |
GeneIDi | 816556 |
Gramenei | AT2G20370.1; AT2G20370.1; AT2G20370 |
KEGGi | ath:AT2G20370 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AY195743 Genomic DNA Translation: AAO39815.1 KJ138908 mRNA Translation: AHL38848.1 AC006569 Genomic DNA Translation: AAD21751.1 Sequence problems. CP002685 Genomic DNA Translation: AEC06999.1 BT023734 mRNA Translation: AAZ23926.1 AK226372 mRNA Translation: BAE98519.1 |
PIRi | D84588 |
RefSeqi | NP_179627.2, NM_127596.3 |
3D structure databases
SMRi | Q7XJ98 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 1909, 8 interactors |
STRINGi | 3702.AT2G20370.1 |
Protein family/group databases
CAZyi | GT47, Glycosyltransferase Family 47 |
PTM databases
SwissPalmi | Q7XJ98 |
Proteomic databases
PaxDbi | Q7XJ98 |
PRIDEi | Q7XJ98 |
ProteomicsDBi | 251380 |
Genome annotation databases
EnsemblPlantsi | AT2G20370.1; AT2G20370.1; AT2G20370 |
GeneIDi | 816556 |
Gramenei | AT2G20370.1; AT2G20370.1; AT2G20370 |
KEGGi | ath:AT2G20370 |
Organism-specific databases
Araporti | AT2G20370 |
TAIRi | locus:2039002, AT2G20370 |
Phylogenomic databases
eggNOGi | KOG1021, Eukaryota |
HOGENOMi | CLU_012659_2_0_1 |
InParanoidi | Q7XJ98 |
OMAi | MNTATEK |
OrthoDBi | 789556at2759 |
PhylomeDBi | Q7XJ98 |
Enzyme and pathway databases
BioCyci | ARA:AT2G20370-MONOMER MetaCyc:AT2G20370-MONOMER |
Miscellaneous databases
PROi | PR:Q7XJ98 |
Gene expression databases
ExpressionAtlasi | Q7XJ98, baseline and differential |
Genevisiblei | Q7XJ98, AT |
Family and domain databases
InterProi | View protein in InterPro IPR004263, Exostosin IPR040911, Exostosin_GT47 |
PANTHERi | PTHR11062, PTHR11062, 1 hit |
Pfami | View protein in Pfam PF03016, Exostosin, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | MUR3_ARATH | |
Accessioni | Q7XJ98Primary (citable) accession number: Q7XJ98 Secondary accession number(s): Q0WWH9 W8QNZ0 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | June 21, 2005 |
Last sequence update: | October 1, 2003 | |
Last modified: | April 7, 2021 | |
This is version 111 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Arabidopsis thaliana
Arabidopsis thaliana: entries and gene names - SIMILARITY comments
Index of protein domains and families