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Entry version 109 (16 Oct 2019)
Sequence version 1 (01 Oct 2003)
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Protein

Probable GTP diphosphokinase RSH2, chloroplastic

Gene

RSH2

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Probable ppGpp (guanosine 3'-diphosphate 5'-diphosphate) synthetase that may be involved in a rapid plant ppGpp-mediated response to pathogens and other stresses.By similarity

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionKinase, Transferase
Biological processStress response
LigandATP-binding, GTP-binding, Nucleotide-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Probable GTP diphosphokinase RSH2, chloroplastic (EC:2.7.6.5)
Alternative name(s):
RelA/SpoT homolog 2
Short name:
OsRSH2
ppGpp synthetase RSH2
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:RSH2
Ordered Locus Names:Os08g0457600, LOC_Os08g35620
ORF Names:OsJ_27564, P0493A04.9
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiOryza sativa subsp. japonica (Rice)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri39947 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliopsidaLiliopsidaPoalesPoaceaeBOP cladeOryzoideaeOryzeaeOryzinaeOryzaOryza sativa
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000059680 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 8

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Chloroplast, Plastid

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a transit peptide.<p><a href='/help/transit' target='_top'>More...</a></p>Transit peptidei1 – 68ChloroplastSequence analysisAdd BLAST68
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000042984969 – 718Probable GTP diphosphokinase RSH2, chloroplasticAdd BLAST650

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q7XAP4

PRoteomics IDEntifications database

More...
PRIDEi
Q7XAP4

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q7XAP4 OS

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
4530.OS08T0457600-01

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q7XAP4

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini243 – 347HDPROSITE-ProRule annotationAdd BLAST105

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the RelA/SpoT family.Curated

Keywords - Domaini

Transit peptide

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1157 Eukaryota
COG0317 LUCA

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q7XAP4

KEGG Orthology (KO)

More...
KOi
K00951

Identification of Orthologs from Complete Genome Data

More...
OMAi
RWTPYGF

Database of Orthologous Groups

More...
OrthoDBi
505873at2759

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00077 HDc, 1 hit
cd05399 NT_Rel-Spo_like, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR003607 HD/PDEase_dom
IPR007685 RelA_SpoT

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF04607 RelA_SpoT, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00471 HDc, 1 hit
SM00954 RelA_SpoT, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51831 HD, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

Q7XAP4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSVPAIAVYT SPPGAVYTSS SSSELEASSR GSAPCATAAP PSPASSHRHQ
60 70 80 90 100
AIAGGLSCLF SSPTAAPRAA AAQDELGALW HDRSGEATAV GGGGGGGGYS
110 120 130 140 150
YPQPSSPFKW RDMLHHSPVP LFHSPASSPA SRSPSASWLA GRERERLFSS
160 170 180 190 200
FVRNALGSCV DYAPVAALPL GVSAAVGVGA GELAFELDEH LSEAEPSCEP
210 220 230 240 250
YARDLLAGAQ ARHRIFHDEL VVKAFFEAER AHRGQTRASG DPYLQHCVET
260 270 280 290 300
AVLLAKIGAN ATVVSAGLLH DTIDDSFMDY DQIFRMFGAG VADLVEGVSK
310 320 330 340 350
LSHLSKLARD NNTASRTVEA DRLHTMFLAM ADARAVLIKL ADRLHNMKTI
360 370 380 390 400
EALPLVKQQR FAKETMEIFV PLANRLGIAS WKDQLENICF KHLNPEEHKE
410 420 430 440 450
LSSKLVISFD EALLTSTLDK LDKGLRDEGI SYHSLSGRHK SLYSIYSKMI
460 470 480 490 500
KKNLTMDDVH DIHGLRLVVD TEQDCYQALD IVHKLWPRVA GRFKDYILHP
510 520 530 540 550
KLNGYRSLHT VIMCEGIHPF EVQIRTKEMH LQAEYGFAAH WRYKEGGCKH
560 570 580 590 600
SFVLQMVEWA RWVLTWQCEA MSKERSSGLG RSDAIRPPCP FPSHSEDCPY
610 620 630 640 650
SYTRQCNHDG PIFVIMLEHD KMSVQELPAN STVVDLMERV GANSPRCSPY
660 670 680 690 700
SFPLKEELRP RVNHKPISDP NRKLCMGDVV ELTPALPHKS LTEYREEIQR
710
MYERGGFALA TTRDGPAS
Length:718
Mass (Da):79,148
Last modified:October 1, 2003 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iC618C46D87617830
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AB095096 mRNA Translation: BAC81140.1
AP004586 Genomic DNA Translation: BAD09583.1
AP008214 Genomic DNA Translation: BAF23883.1
AP014964 Genomic DNA Translation: BAT05740.1
CM000145 Genomic DNA Translation: EEE68808.1
AK065020 mRNA Translation: BAG89329.1
AK099624 mRNA Translation: BAG94226.1

NCBI Reference Sequences

More...
RefSeqi
XP_015650642.1, XM_015795156.1

Genome annotation databases

Ensembl plant genome annotation project

More...
EnsemblPlantsi
Os08t0457600-01; Os08t0457600-01; Os08g0457600
Os08t0457600-02; Os08t0457600-02; Os08g0457600

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
4345756

Gramene; a comparative resource for plants

More...
Gramenei
Os08t0457600-01; Os08t0457600-01; Os08g0457600
Os08t0457600-02; Os08t0457600-02; Os08g0457600

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
osa:4345756

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB095096 mRNA Translation: BAC81140.1
AP004586 Genomic DNA Translation: BAD09583.1
AP008214 Genomic DNA Translation: BAF23883.1
AP014964 Genomic DNA Translation: BAT05740.1
CM000145 Genomic DNA Translation: EEE68808.1
AK065020 mRNA Translation: BAG89329.1
AK099624 mRNA Translation: BAG94226.1
RefSeqiXP_015650642.1, XM_015795156.1

3D structure databases

SMRiQ7XAP4
ModBaseiSearch...

Protein-protein interaction databases

STRINGi4530.OS08T0457600-01

Proteomic databases

PaxDbiQ7XAP4
PRIDEiQ7XAP4

Genome annotation databases

EnsemblPlantsiOs08t0457600-01; Os08t0457600-01; Os08g0457600
Os08t0457600-02; Os08t0457600-02; Os08g0457600
GeneIDi4345756
GrameneiOs08t0457600-01; Os08t0457600-01; Os08g0457600
Os08t0457600-02; Os08t0457600-02; Os08g0457600
KEGGiosa:4345756

Phylogenomic databases

eggNOGiKOG1157 Eukaryota
COG0317 LUCA
InParanoidiQ7XAP4
KOiK00951
OMAiRWTPYGF
OrthoDBi505873at2759

Gene expression databases

GenevisibleiQ7XAP4 OS

Family and domain databases

CDDicd00077 HDc, 1 hit
cd05399 NT_Rel-Spo_like, 1 hit
InterProiView protein in InterPro
IPR003607 HD/PDEase_dom
IPR007685 RelA_SpoT
PfamiView protein in Pfam
PF04607 RelA_SpoT, 1 hit
SMARTiView protein in SMART
SM00471 HDc, 1 hit
SM00954 RelA_SpoT, 1 hit
PROSITEiView protein in PROSITE
PS51831 HD, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiRSH2_ORYSJ
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q7XAP4
Secondary accession number(s): A0A0P0XGI7
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 9, 2014
Last sequence update: October 1, 2003
Last modified: October 16, 2019
This is version 109 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Oryza sativa (rice)
    Index of Oryza sativa entries and their corresponding gene designations
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