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UniProtKB - Q7XA06 (SYT3_ARATH)
Protein
Synaptotagmin-3
Gene
SYT3
Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Functioni
May be involved in membrane trafficking.
By similarityCofactori
Ca2+PROSITE-ProRule annotation
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Metal bindingi | 277 | Calcium 1PROSITE-ProRule annotation | 1 | |
Metal bindingi | 277 | Calcium 2PROSITE-ProRule annotation | 1 | |
Metal bindingi | 283 | Calcium 1PROSITE-ProRule annotation | 1 | |
Metal bindingi | 333 | Calcium 1PROSITE-ProRule annotation | 1 | |
Metal bindingi | 333 | Calcium 2PROSITE-ProRule annotation | 1 | |
Metal bindingi | 335 | Calcium 1PROSITE-ProRule annotation | 1 | |
Metal bindingi | 335 | Calcium 2PROSITE-ProRule annotation | 1 | |
Metal bindingi | 341 | Calcium 2PROSITE-ProRule annotation | 1 |
GO - Molecular functioni
- lipid binding Source: UniProtKB-KW
- metal ion binding Source: UniProtKB-KW
GO - Biological processi
- lipid transport Source: UniProtKB-KW
Keywordsi
Biological process | Lipid transport, Transport |
Ligand | Calcium, Lipid-binding, Metal-binding |
Names & Taxonomyi
Protein namesi | Recommended name: Synaptotagmin-3Alternative name(s): NTMC2T1.3 Synaptotagmin C |
Gene namesi | Name:SYT3 Synonyms:SYTC Ordered Locus Names:At5g04220 ORF Names:F21E1.140 |
Organismi | Arabidopsis thaliana (Mouse-ear cress) |
Taxonomic identifieri | 3702 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › eudicotyledons › Gunneridae › Pentapetalae › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis |
Proteomesi |
|
Organism-specific databases
Araporti | AT5G04220 |
TAIRi | locus:2146688, AT5G04220 |
Subcellular locationi
Other locations
- Membrane By similarity; Single-pass membrane protein By similarity
Endoplasmic reticulum
- endoplasmic reticulum Source: GO_Central
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 9 – 29 | HelicalSequence analysisAdd BLAST | 21 |
Keywords - Cellular componenti
MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000419240 | 1 – 540 | Synaptotagmin-3Add BLAST | 540 |
Proteomic databases
PaxDbi | Q7XA06 |
PRIDEi | Q7XA06 |
ProteomicsDBi | 234109 [Q7XA06-1] |
PTM databases
iPTMneti | Q7XA06 |
Expressioni
Gene expression databases
ExpressionAtlasi | Q7XA06, baseline and differential |
Genevisiblei | Q7XA06, AT |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 67 – 249 | SMP-LTDPROSITE-ProRule annotationAdd BLAST | 183 | |
Domaini | 240 – 363 | C2 1PROSITE-ProRule annotationAdd BLAST | 124 | |
Domaini | 401 – 521 | C2 2PROSITE-ProRule annotationAdd BLAST | 121 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 227 – 509 | Phospholipid bindingBy similarityAdd BLAST | 283 |
Sequence similaritiesi
Belongs to the synaptotagmin family.Curated
Keywords - Domaini
Repeat, Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | KOG1012, Eukaryota |
HOGENOMi | CLU_028927_1_0_1 |
InParanoidi | Q7XA06 |
PhylomeDBi | Q7XA06 |
Family and domain databases
Gene3Di | 2.60.40.150, 2 hits |
InterProi | View protein in InterPro IPR000008, C2_dom IPR035892, C2_domain_sf IPR031468, SMP_LBD IPR045050, Synaptotagmin_plant IPR039010, Synaptotagmin_SMP |
PANTHERi | PTHR10774, PTHR10774, 1 hit |
Pfami | View protein in Pfam PF00168, C2, 2 hits PF17047, SMP_LBD, 1 hit |
PRINTSi | PR00360, C2DOMAIN |
SMARTi | View protein in SMART SM00239, C2, 2 hits |
SUPFAMi | SSF49562, SSF49562, 2 hits |
PROSITEi | View protein in PROSITE PS50004, C2, 2 hits PS51847, SMP, 1 hit |
s (2+)i Sequence
Sequence statusi: Complete.
This entry describes 2 produced by isoformsialternative splicing. AlignAdd to basketThis entry has 2 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All
Isoform 1 (identifier: Q7XA06-1) [UniParc]FASTAAdd to basket
This isoform has been chosen as the sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. canonicali
10 20 30 40 50
MGFFTSVLGI IGFVIGIPIG LILGFFVLIY SQPSHQEYPP ARPLVETSIS
60 70 80 90 100
VLLDLLPDIP LWMKNPDYER VDWFNKFISY MWPYLDKAVC GIIRSSVQPL
110 120 130 140 150
FADYIGTFCI ESIEFENLSL GTLPPTVHGV KFYETNEKEL LFEPSIKWAG
160 170 180 190 200
NPNIVLVLKV LSLRIRVQLV DLQFFAIVRV ALKPLLPTFP CFGMVVVSLM
210 220 230 240 250
EKPHVDFGLK VLGGDLMSIP GLYRYVQETI KRQVSSMYHW PQVLEIPILD
260 270 280 290 300
SSTASVKKPV GLLHVSILRA RNLLKKDLLG TSDPYVKLSL TGEKLPAKKT
310 320 330 340 350
TIKKRNLNPE WNEHFKLIVK DPNSQVLQLE VFDWDKVGGH DRLGMQMIPL
360 370 380 390 400
QKINPGERKE FNLDLIKNSN VVMDSGDKKK RGRLEVDLRY VPFREESIKR
410 420 430 440 450
RKESREEKSS EDDDFLSQAG LLSVAVQSAK DVEGKKKHSN PYAVVLFRGE
460 470 480 490 500
KKKTKMLKKT RDPRWNEEFQ FTLEEPPVKE SIRVEVMSKG TGFHFRSKEE
510 520 530 540
LGHVDINLDD VVDNGRINQK YHLINSRNGI IHIEIRWTTS
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketA0A1P8BD17 | A0A1P8BD17_ARATH | Calcium-dependent lipid-binding (Ca... | SYTC ATSYTC, NTMC2T1.3, NTMC2TYPE1.3, synaptotagmin 3, SYT3 | 478 | Annotation score: |
Sequence cautioni
The sequence CAC05504 differs from that shown. Reason: Erroneous gene model prediction.Curated
Alternative sequence
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Alternative sequenceiVSP_044138 | 1 – 227 | MGFFT…YRYVQ → MILLS in isoform 2. 1 PublicationAdd BLAST | 227 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AB102952 mRNA Translation: BAC76813.1 FM213367 mRNA Translation: CAR82572.1 FM213368 mRNA Translation: CAR82573.1 AL391716 Genomic DNA Translation: CAC05504.1 Sequence problems. CP002688 Genomic DNA Translation: AED90712.1 CP002688 Genomic DNA Translation: AED90713.1 |
RefSeqi | NP_568135.1, NM_120504.2 [Q7XA06-2] NP_974729.1, NM_203000.2 [Q7XA06-1] |
Genome annotation databases
EnsemblPlantsi | AT5G04220.1; AT5G04220.1; AT5G04220 [Q7XA06-2] AT5G04220.2; AT5G04220.2; AT5G04220 [Q7XA06-1] |
GeneIDi | 830301 |
Gramenei | AT5G04220.1; AT5G04220.1; AT5G04220 [Q7XA06-2] AT5G04220.2; AT5G04220.2; AT5G04220 [Q7XA06-1] |
KEGGi | ath:AT5G04220 |
Keywords - Coding sequence diversityi
Alternative splicingSimilar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AB102952 mRNA Translation: BAC76813.1 FM213367 mRNA Translation: CAR82572.1 FM213368 mRNA Translation: CAR82573.1 AL391716 Genomic DNA Translation: CAC05504.1 Sequence problems. CP002688 Genomic DNA Translation: AED90712.1 CP002688 Genomic DNA Translation: AED90713.1 |
RefSeqi | NP_568135.1, NM_120504.2 [Q7XA06-2] NP_974729.1, NM_203000.2 [Q7XA06-1] |
3D structure databases
SMRi | Q7XA06 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 3702.AT5G04220.2 |
PTM databases
iPTMneti | Q7XA06 |
Proteomic databases
PaxDbi | Q7XA06 |
PRIDEi | Q7XA06 |
ProteomicsDBi | 234109 [Q7XA06-1] |
Genome annotation databases
EnsemblPlantsi | AT5G04220.1; AT5G04220.1; AT5G04220 [Q7XA06-2] AT5G04220.2; AT5G04220.2; AT5G04220 [Q7XA06-1] |
GeneIDi | 830301 |
Gramenei | AT5G04220.1; AT5G04220.1; AT5G04220 [Q7XA06-2] AT5G04220.2; AT5G04220.2; AT5G04220 [Q7XA06-1] |
KEGGi | ath:AT5G04220 |
Organism-specific databases
Araporti | AT5G04220 |
TAIRi | locus:2146688, AT5G04220 |
Phylogenomic databases
eggNOGi | KOG1012, Eukaryota |
HOGENOMi | CLU_028927_1_0_1 |
InParanoidi | Q7XA06 |
PhylomeDBi | Q7XA06 |
Miscellaneous databases
PROi | PR:Q7XA06 |
Gene expression databases
ExpressionAtlasi | Q7XA06, baseline and differential |
Genevisiblei | Q7XA06, AT |
Family and domain databases
Gene3Di | 2.60.40.150, 2 hits |
InterProi | View protein in InterPro IPR000008, C2_dom IPR035892, C2_domain_sf IPR031468, SMP_LBD IPR045050, Synaptotagmin_plant IPR039010, Synaptotagmin_SMP |
PANTHERi | PTHR10774, PTHR10774, 1 hit |
Pfami | View protein in Pfam PF00168, C2, 2 hits PF17047, SMP_LBD, 1 hit |
PRINTSi | PR00360, C2DOMAIN |
SMARTi | View protein in SMART SM00239, C2, 2 hits |
SUPFAMi | SSF49562, SSF49562, 2 hits |
PROSITEi | View protein in PROSITE PS50004, C2, 2 hits PS51847, SMP, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | SYT3_ARATH | |
Accessioni | Q7XA06Primary (citable) accession number: Q7XA06 Secondary accession number(s): B6ETT6, Q9FYD9 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | October 3, 2012 |
Last sequence update: | October 1, 2003 | |
Last modified: | February 23, 2022 | |
This is version 116 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Arabidopsis thaliana
Arabidopsis thaliana: entries and gene names - SIMILARITY comments
Index of protein domains and families