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UniProtKB - Q7WY72 (REMA_BACSU)
Protein
Extracellular matrix regulatory protein A
Gene
remA
Organism
Bacillus subtilis (strain 168)
Status
Functioni
Regulates the biosynthesis of the extracellular matrix and the biofilm formation (PubMed:19363116, PubMed:23646920).
Activates the transcription of the matrix biosynthesis operons eps and tapA-sipW-tasA. Also activates expression of the opuA operon, involved in osmoprotection. Acts by binding specifically to the promoter region of the target genes (PubMed:23646920).
Acts in parallel to the pathway that governs SinR derepression (PubMed:19363116, PubMed:23646920).
Required for endosporulation (PubMed:23396918).
3 PublicationsGO - Molecular functioni
- DNA binding Source: UniProtKB-KW
Keywordsi
Molecular function | DNA-binding |
Biological process | Transcription, Transcription regulation |
Enzyme and pathway databases
BioCyci | BSUB:BSU15670-MONOMER |
Names & Taxonomyi
Protein namesi | Recommended name: Extracellular matrix regulatory protein ACuratedAlternative name(s): Regulator of extracellular matrix A1 Publication |
Gene namesi | Name:remA1 Publication Synonyms:ylzA Ordered Locus Names:BSU15670 |
Organismi | Bacillus subtilis (strain 168) |
Taxonomic identifieri | 224308 [NCBI] |
Taxonomic lineagei | Bacteria › Firmicutes › Bacilli › Bacillales › Bacillaceae › Bacillus › |
Proteomesi |
|
Pathology & Biotechi
Disruption phenotypei
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000050223 | 1 – 89 | Extracellular matrix regulatory protein AAdd BLAST | 89 |
Proteomic databases
PaxDbi | Q7WY72 |
Expressioni
Developmental stagei
Expressed in the forespore during sporulation.1 Publication
Structurei
Family & Domainsi
Sequence similaritiesi
Phylogenomic databases
eggNOGi | COG2052, Bacteria |
InParanoidi | Q7WY72 |
OMAi | RDRNMLI |
PhylomeDBi | Q7WY72 |
Family and domain databases
HAMAPi | MF_01503, RemA, 1 hit |
InterProi | View protein in InterPro IPR007169, RemA |
PANTHERi | PTHR38449, PTHR38449, 1 hit |
Pfami | View protein in Pfam PF04025, DUF370, 1 hit |
i Sequence
Sequence statusi: Complete.
Q7WY72-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MTIKLINIGF GNIISANRMI SIVSPESAPI KRMIQDARDR GMLIDATYGR
60 70 80
RTRAVVVMDS DHIILSAVQP ETVAHRLSVK EEIMDEGQG
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL009126 Genomic DNA Translation: CAE01452.1 |
RefSeqi | NP_570902.1, NC_000964.3 WP_003154355.1, NZ_JNCM01000035.1 |
Genome annotation databases
EnsemblBacteriai | CAE01452; CAE01452; BSU_15670 |
GeneIDi | 64303458 66326444 937956 |
KEGGi | bsu:BSU15670 |
PATRICi | fig|224308.179.peg.1707 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL009126 Genomic DNA Translation: CAE01452.1 |
RefSeqi | NP_570902.1, NC_000964.3 WP_003154355.1, NZ_JNCM01000035.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 224308.BSU15670 |
Proteomic databases
PaxDbi | Q7WY72 |
Protocols and materials databases
DNASUi | 937956 |
Genome annotation databases
EnsemblBacteriai | CAE01452; CAE01452; BSU_15670 |
GeneIDi | 64303458 66326444 937956 |
KEGGi | bsu:BSU15670 |
PATRICi | fig|224308.179.peg.1707 |
Phylogenomic databases
eggNOGi | COG2052, Bacteria |
InParanoidi | Q7WY72 |
OMAi | RDRNMLI |
PhylomeDBi | Q7WY72 |
Enzyme and pathway databases
BioCyci | BSUB:BSU15670-MONOMER |
Miscellaneous databases
PROi | PR:Q7WY72 |
Family and domain databases
HAMAPi | MF_01503, RemA, 1 hit |
InterProi | View protein in InterPro IPR007169, RemA |
PANTHERi | PTHR38449, PTHR38449, 1 hit |
Pfami | View protein in Pfam PF04025, DUF370, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | REMA_BACSU | |
Accessioni | Q7WY72Primary (citable) accession number: Q7WY72 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | February 2, 2004 |
Last sequence update: | October 1, 2003 | |
Last modified: | February 23, 2022 | |
This is version 82 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Uncharacterized protein families (UPF)
List of uncharacterized protein family (UPF) entries - SIMILARITY comments
Index of protein domains and families