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Entry version 103 (07 Oct 2020)
Sequence version 1 (01 Oct 2003)
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Protein
Submitted name:

Nonribosomal peptide synthetase McyC

Gene

mcyC

Organism
Anabaena sp. 90
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

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BioCyci
ASP46234:G1HCB-1014-MONOMER

Protein family/group databases

ESTHER database of the Alpha/Beta-hydrolase fold superfamily of proteins

More...
ESTHERi
9nost-q7wrj5, Thioesterase

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Nonribosomal peptide synthetase McyCImported
Submitted name:
Peptide synthetaseImported
Submitted name:
Peptide sythetaseImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:mcyCImported
ORF Names:ANA_C10987Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiAnabaena sp. 90Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri46234 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaCyanobacteriaNostocalesNostocaceaeAnabaenaunclassified Anabaena
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000010101 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome chANA01

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei1010O-(pantetheine 4'-phosphoryl)serinePROSITE-ProRule annotation1

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - PTMi

PhosphopantetheinePROSITE-ProRule annotationARBA annotation, PhosphoproteinARBA annotation

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
46234.ANA_C10987

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini975 – 1050CarrierInterPro annotationAdd BLAST76

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the ATP-dependent AMP-binding enzyme family.ARBA annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
COG1020, Bacteria

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_000022_2_4_3

Database of Orthologous Groups

More...
OrthoDBi
572620at2

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.1200.10, 1 hit
3.30.559.10, 1 hit
3.40.50.12780, 1 hit
3.40.50.1820, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR010071, AA_adenyl_domain
IPR029058, AB_hydrolase
IPR036736, ACP-like_sf
IPR025110, AMP-bd_C
IPR020459, AMP-binding
IPR020845, AMP-binding_CS
IPR000873, AMP-dep_Synth/Lig
IPR042099, AMP-dep_Synthh-like_sf
IPR023213, CAT-like_dom_sf
IPR001242, Condensatn
IPR009081, PP-bd_ACP
IPR001031, Thioesterase

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00501, AMP-binding, 1 hit
PF13193, AMP-binding_C, 1 hit
PF00668, Condensation, 1 hit
PF00550, PP-binding, 1 hit
PF00975, Thioesterase, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00154, AMPBINDING

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF47336, SSF47336, 1 hit
SSF53474, SSF53474, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR01733, AA-adenyl-dom, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00455, AMP_BINDING, 1 hit
PS50075, CARRIER, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q7WRJ5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MINSLPNQQY YEVSHAQRRM WILHHISEYS SAYNIRLAMR INGSLDIAAF
60 70 80 90 100
TAAFQQIVNR HEILRTTFTN IAGSIQQIVH EEVPKEQLVV FRDLREQKDA
110 120 130 140 150
ETIADSLIQE SANSRFDLEK LHLMRVLLVQ IKPEEFLFGL TIHHIIGDAR
160 170 180 190 200
SLDIIFQEFV TLYSACTQQK TAALPALPLQ YKDYTAWQNQ WLESEEAKEQ
210 220 230 240 250
CNYWCDRFAG EPPILNLPTD FPRPQFKSSQ AGIYTYNFSQ SLSEKLRSFA
260 270 280 290 300
AGNHTTLFIT LLTLFKILLH RYTGQHDLVI GIPISGRNHP DLENQIGFYV
310 320 330 340 350
NTLALRTLLP KVGTFQQALA EVTNTCLDAY EYNEYPFDKL VSALDLEHDL
360 370 380 390 400
TRNPLFDVMF SLLSKDSKAV IKIPGIEHQA YPLKPRTAQF DLSWSLFEDT
410 420 430 440 450
NDLRLVIEYE PDLFREETIA RMSGHFLQII QAVVENPNCQ LSQINLLTSE
460 470 480 490 500
ELYQLLIEWN NTEVAYPQDK CIHDLFEEQV ERNPNAVAVI FEGQQLTYQQ
510 520 530 540 550
LNQKANQLAH YLRTKGVEPE VLVGIFVERS IEMLIGLLGI LKAGGAYVPL
560 570 580 590 600
DPSYPNDRLI YMLTDAAVSI LLTQQSLVYS LQANSAEVVC LDRDWHIIAN
610 620 630 640 650
YSQHNPVKLV KAENLAYVIY TSGSTGKPKG VMITHQGICN NLLRTIDTYP
660 670 680 690 700
LIAGDCILHI GVLSFDVSVW EIFWSLTSGT TLVVAKPEGH KDIAYLINLI
710 720 730 740 750
AQQQVTQACF VPSMLRIFLQ QPNLESCRYL KRVFSGAETL SYELTQRFFE
760 770 780 790 800
RLDCELHNLY GPTETAVDAT CWQCQPDSNC RIIPIGRPIA NTQTYILDQY
810 820 830 840 850
LQPVPIGIAG ELHIGGVSLA RGYLNQPELT NEKFISNPFG EGKLYKTGDL
860 870 880 890 900
ARYLSDGNIE YLGRIDHQVK LRGLRIELGE IEFLLDTHPQ VEQTVVILQA
910 920 930 940 950
NTSENQRLVA YVVRKNSSLT PSELRRFLQQ KLPAYMIPSA FVVLSELPLN
960 970 980 990 1000
PNGKIDRRKL PQPDETSIVE LPYLPPRNSS ERILVSIWQQ VLQVSKVGVN
1010 1020 1030 1040 1050
DNFFDLGGHS LQAMNLMALI YQELEIEIPL SMIYEKPTVA ELSKYIIYAK
1060 1070 1080 1090 1100
EMNIQPKERP YIVFNQAREK AVFIFPPALG FAAAYANLAD YLTDYAIYTF
1110 1120 1130 1140 1150
RYIADEATLE KYAELIDDIA PNQDLKLMGH SAGGFLAMLM AQKLESRDRV
1160 1170 1180 1190 1200
VSDVILIDTY RGGREAQQAE MSEIIEGVDT FLLNPKRQEL RRYFMENQKL
1210 1220 1230 1240 1250
RDLTYNQVWE YFNFLWYSDL KNVQINGNIH LIRAEGNYDY EDDWIQATRG
1260 1270 1280
QRINYYAHGV HREIIDPPYL NQNATIINAI LSQN
Length:1,284
Mass (Da):146,879
Last modified:October 1, 2003 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iE00EA97A4D516746
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AY212249 Genomic DNA Translation: AAO62588.1
CP003284 Genomic DNA Translation: AFW93777.1
AJ536156 Genomic DNA Translation: CAD60103.1

NCBI Reference Sequences

More...
RefSeqi
WP_015078941.1, NC_019427.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
AFW93777; AFW93777; ANA_C10987

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
anb:ANA_C10987

Pathosystems Resource Integration Center (PATRIC)

More...
PATRICi
fig|46234.3.peg.1096

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY212249 Genomic DNA Translation: AAO62588.1
CP003284 Genomic DNA Translation: AFW93777.1
AJ536156 Genomic DNA Translation: CAD60103.1
RefSeqiWP_015078941.1, NC_019427.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi46234.ANA_C10987

Protein family/group databases

ESTHERi9nost-q7wrj5, Thioesterase

Genome annotation databases

EnsemblBacteriaiAFW93777; AFW93777; ANA_C10987
KEGGianb:ANA_C10987
PATRICifig|46234.3.peg.1096

Phylogenomic databases

eggNOGiCOG1020, Bacteria
HOGENOMiCLU_000022_2_4_3
OrthoDBi572620at2

Enzyme and pathway databases

BioCyciASP46234:G1HCB-1014-MONOMER

Family and domain databases

Gene3Di1.10.1200.10, 1 hit
3.30.559.10, 1 hit
3.40.50.12780, 1 hit
3.40.50.1820, 1 hit
InterProiView protein in InterPro
IPR010071, AA_adenyl_domain
IPR029058, AB_hydrolase
IPR036736, ACP-like_sf
IPR025110, AMP-bd_C
IPR020459, AMP-binding
IPR020845, AMP-binding_CS
IPR000873, AMP-dep_Synth/Lig
IPR042099, AMP-dep_Synthh-like_sf
IPR023213, CAT-like_dom_sf
IPR001242, Condensatn
IPR009081, PP-bd_ACP
IPR001031, Thioesterase
PfamiView protein in Pfam
PF00501, AMP-binding, 1 hit
PF13193, AMP-binding_C, 1 hit
PF00668, Condensation, 1 hit
PF00550, PP-binding, 1 hit
PF00975, Thioesterase, 1 hit
PRINTSiPR00154, AMPBINDING
SUPFAMiSSF47336, SSF47336, 1 hit
SSF53474, SSF53474, 1 hit
TIGRFAMsiTIGR01733, AA-adenyl-dom, 1 hit
PROSITEiView protein in PROSITE
PS00455, AMP_BINDING, 1 hit
PS50075, CARRIER, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ7WRJ5_9NOST
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q7WRJ5
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: October 1, 2003
Last sequence update: October 1, 2003
Last modified: October 7, 2020
This is version 103 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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