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Entry version 127 (13 Nov 2019)
Sequence version 2 (01 Mar 2004)
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Protein

Elongator complex protein 1

Gene

Elp1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Component of the RNA polymerase II elongator complex, a multiprotein complex associated with the RNA polymerase II (Pol II) holoenzyme, and which is involved in transcriptional elongation. The elongator complex catalyzes formation of carboxymethyluridine in the wobble base at position 34 in tRNAs (By similarity). Involved in neurogenesis (PubMed:22854966). Regulates the migration and branching of projection neurons in the developing cerebral cortex, through a process depending on alpha-tubulin acetylation (PubMed:22854966). May act as a scaffold protein that may assemble active IKK-MAP3K14 complexes (IKKA, IKKB and MAP3K14/NIK) (By similarity).By similarity1 Publication

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: 5-methoxycarbonylmethyl-2-thiouridine-tRNA biosynthesis

This protein is involved in the pathway 5-methoxycarbonylmethyl-2-thiouridine-tRNA biosynthesis, which is part of tRNA modification.By similarity
View all proteins of this organism that are known to be involved in the pathway 5-methoxycarbonylmethyl-2-thiouridine-tRNA biosynthesis and in tRNA modification.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processTranscription, Transcription regulation, tRNA processing

Enzyme and pathway databases

UniPathway: a resource for the exploration and annotation of metabolic pathways

More...
UniPathwayi
UPA00988

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Elongator complex protein 1
Short name:
ELP1
Alternative name(s):
IkappaB kinase complex-associated protein
Short name:
IKK complex-associated protein
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Elp1
Synonyms:Ikap, Ikbkap
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 4

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1914544 Elp1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002839951 – 1333Elongator complex protein 1Add BLAST1333

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei805PhosphoserineBy similarity1
Modified residuei1172PhosphoserineBy similarity1
Modified residuei1175PhosphoserineBy similarity1

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

Phosphorylated.By similarity

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q7TT37

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q7TT37

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q7TT37

PeptideAtlas

More...
PeptideAtlasi
Q7TT37

PRoteomics IDEntifications database

More...
PRIDEi
Q7TT37

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q7TT37

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q7TT37

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Widely expressed with highest levels in brain.1 Publication

<p>This subsection of the ‘Expression’ section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified ‘at the protein level’.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

Expressed at embryonic days 7, 11, 15 and 17 with the highest expression at embryonic day 11.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000028431 Expressed in 277 organ(s), highest expression level in forebrain

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q7TT37 MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Component of the RNA polymerase II elongator complex (Elongator), which consists of ELP1, STIP1/ELP2, ELP3, ELP4, ELP5 and ELP6. Elongator associates with the C-terminal domain (CTD) of Pol II largest subunit.

Interacts with ELP3.

Interacts preferentially with MAP3K14/NIK followed by IKK-alpha and IKK-beta.

By similarity

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

WithEntry#Exp.IntActNotes
P232423EBI-8418161,EBI-298630

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
230947, 4 interactors

Protein interaction database and analysis system

More...
IntActi
Q7TT37, 3 interactors

Molecular INTeraction database

More...
MINTi
Q7TT37

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000030140

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the ELP1/IKA1 family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1920 Eukaryota
COG5290 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000013344

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q7TT37

KEGG Orthology (KO)

More...
KOi
K11373

Identification of Orthologs from Complete Genome Data

More...
OMAi
QSQKDPR

Database of Orthologous Groups

More...
OrthoDBi
180136at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q7TT37

TreeFam database of animal gene trees

More...
TreeFami
TF300402

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR006849 Elp1

The PANTHER Classification System

More...
PANTHERi
PTHR12747 PTHR12747, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF04762 IKI3, 1 hit

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF017233 IKAP, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q7TT37-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRNLKLHRTL EFRDIQAPGK PQCFCLRAEQ GTVLIGSERG LTEVDPVRRE
60 70 80 90 100
VKTEISLVAE GFLPEDGSGC IVGIQDLLDQ ESVCVATASG DVIVCNLSTQ
110 120 130 140 150
QLECVGSVAS GISVMSWSPD QELLLLATAQ QTLIMMTKDF EVIAEEQIHQ
160 170 180 190 200
DDFGEGKFVT VGWGSKQTQF HGSEGRPTAF PVQLPENALP WDDRRPHITW
210 220 230 240 250
RGDGQYFAVS VVCRQTEARK IRVWNREFAL QSTSESVPGL GPALAWKPSG
260 270 280 290 300
SLIASTQDKP NQQDVVFFEK NGLLHGHFTL PFLKDEVKVN DLLWNADSSV
310 320 330 340 350
LAIWLEDLPK EDSSTLKSYV QLWTVGNYHW YLKQSLPFST TGKNQIVSLL
360 370 380 390 400
WDPVTPCRLH VLCTGWRYLC CDWHWTTDRS SGNSANDLAN VAVIDGNRVL
410 420 430 440 450
VTVFRQTVVP PPMCTYRLLI PHPVNQVIFS AHLGNDLAVL DASNQISVYK
460 470 480 490 500
CGDKPNMDST VKLGAVGGNG FKVPLTTPHL EKRYSIQFGN NEEEEEEEVN
510 520 530 540 550
ALQLSFLTWV EDDTFLAISY SHSSSQSIIH HLTVTHSEVD EEQGQLDVSS
560 570 580 590 600
SVTVDGVVIG LCCCSKTKSL AVQLADGQVL KYLWESPSLA VEPWKNSEGI
610 620 630 640 650
PVRFVHPCTQ MEVATIGGEE CVLGLTDRCR FFINDTEVAS NITSFAVCDD
660 670 680 690 700
FLLVTTHSHT CQVFSLSGAS LKMLQAALSG SHEASGEILR KVERGSRIVT
710 720 730 740 750
VVPQDTKLIL QMPRGNLEVV HHRALVLAQI RKWLDKLMFK EAFECMRKLR
760 770 780 790 800
INLNLIHDHN PKVFLENVET FVKQIDSVNH INLFFTELRE EDVTKTMYPP
810 820 830 840 850
PITKSVQVST HPDGKKLDLI CDAMRAAMEA INPRKFCLSI LTSHVKKTTP
860 870 880 890 900
ELEIVLQKVQ ELQGNLPFDP ESVSVEEALK YLLLLVDVNE LFNHSLGTYD
910 920 930 940 950
FNLVLMVAEK SQKDPKEYLP FLNTLKKMET NYQRFTIDKY LKRYEKALGH
960 970 980 990 1000
LSKCGPEYFT ECLNLIKDKN LYKEALKLYR PDSPQYQAVS MAYGEHLMQE
1010 1020 1030 1040 1050
HLYEPAGLVF ARCGAQEKAL EAFLACGSWQ QALCVAAQLQ MSKDKVAGLA
1060 1070 1080 1090 1100
RTLAGKLVEQ RKHSEAATVL EQYAQDYEEA VLLLLEGSAW EEALRLVYKY
1110 1120 1130 1140 1150
DRVDIIETSV KPSILEAQKN YMDFLDSETA TFIRHKNRLQ VVRALRRQAP
1160 1170 1180 1190 1200
QVHVDHEVAH GPESDLFSET SSIMSGSEMS GRYSHSNSRI SARSSKNRRK
1210 1220 1230 1240 1250
AERKKHSLKE GSPLEGLALL EALSEVVQSV EKLKDEVRAI LKVLFLFEFE
1260 1270 1280 1290 1300
EQAKELQRAF ESTLQLMERA VPEIWTPAGQ QSSTTPVLGP SSTANSITAS
1310 1320 1330
YQQQKTCVPA LDAGVYMPPK MDPRSQWKLS LLE
Length:1,333
Mass (Da):149,584
Last modified:March 1, 2004 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iC40E0098DD4DF63C
GO

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAL36025 differs from that shown. Reason: Frameshift.Curated
The sequence AAO15309 differs from that shown. Reason: Frameshift.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti42T → P in AAO15309 (Ref. 3) Curated1
Sequence conflicti120D → G in BAE27720 (PubMed:16141072).Curated1
Sequence conflicti215 – 216QT → HS in AAO15309 (Ref. 3) Curated2
Sequence conflicti221I → V in AAL40925 (PubMed:11722848).Curated1
Sequence conflicti346I → V in AAL40925 (PubMed:11722848).Curated1
Sequence conflicti346I → V in AAO15309 (Ref. 3) Curated1
Sequence conflicti582Y → I in AAL36025 (PubMed:11747609).Curated1
Sequence conflicti634 – 635ND → LV in AAL36025 (PubMed:11747609).Curated2
Sequence conflicti649D → A in AAL40925 (PubMed:11722848).Curated1
Sequence conflicti663V → G in AAL36025 (PubMed:11747609).Curated1
Sequence conflicti663V → G in AAL40925 (PubMed:11722848).Curated1
Sequence conflicti663V → G in AAO15309 (Ref. 3) Curated1
Sequence conflicti693 – 694ER → VW in AAL36025 (PubMed:11747609).Curated2
Sequence conflicti773K → F in AAL36025 (PubMed:11747609).Curated1
Sequence conflicti1110V → I in AAL36025 (PubMed:11747609).Curated1
Sequence conflicti1110V → I in AAL40925 (PubMed:11722848).Curated1
Sequence conflicti1110V → I in AAO15309 (Ref. 3) Curated1
Sequence conflicti1159A → G in BAB23291 (PubMed:16141072).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF367244 mRNA Translation: AAL36025.1 Frameshift.
AF387811 mRNA Translation: AAL40925.1
AF140786 mRNA Translation: AAO15309.1 Frameshift.
AK004402 mRNA Translation: BAB23291.1
AK076152 mRNA Translation: BAC36221.1
AK035944 mRNA Translation: BAC29252.1
AK147153 mRNA Translation: BAE27720.1
AL807762 Genomic DNA No translation available.
AL929577 Genomic DNA No translation available.
BC052387 mRNA Translation: AAH52387.2
BC054468 mRNA Translation: AAH54468.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS38765.1

NCBI Reference Sequences

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RefSeqi
NP_080355.2, NM_026079.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000030140; ENSMUSP00000030140; ENSMUSG00000028431

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
230233

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:230233

UCSC genome browser

More...
UCSCi
uc012del.1 mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF367244 mRNA Translation: AAL36025.1 Frameshift.
AF387811 mRNA Translation: AAL40925.1
AF140786 mRNA Translation: AAO15309.1 Frameshift.
AK004402 mRNA Translation: BAB23291.1
AK076152 mRNA Translation: BAC36221.1
AK035944 mRNA Translation: BAC29252.1
AK147153 mRNA Translation: BAE27720.1
AL807762 Genomic DNA No translation available.
AL929577 Genomic DNA No translation available.
BC052387 mRNA Translation: AAH52387.2
BC054468 mRNA Translation: AAH54468.1
CCDSiCCDS38765.1
RefSeqiNP_080355.2, NM_026079.3

3D structure databases

Database of comparative protein structure models

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ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGridi230947, 4 interactors
IntActiQ7TT37, 3 interactors
MINTiQ7TT37
STRINGi10090.ENSMUSP00000030140

PTM databases

iPTMnetiQ7TT37
PhosphoSitePlusiQ7TT37

Proteomic databases

EPDiQ7TT37
MaxQBiQ7TT37
PaxDbiQ7TT37
PeptideAtlasiQ7TT37
PRIDEiQ7TT37

Genome annotation databases

EnsembliENSMUST00000030140; ENSMUSP00000030140; ENSMUSG00000028431
GeneIDi230233
KEGGimmu:230233
UCSCiuc012del.1 mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
8518
MGIiMGI:1914544 Elp1

Phylogenomic databases

eggNOGiKOG1920 Eukaryota
COG5290 LUCA
GeneTreeiENSGT00390000013344
InParanoidiQ7TT37
KOiK11373
OMAiQSQKDPR
OrthoDBi180136at2759
PhylomeDBiQ7TT37
TreeFamiTF300402

Enzyme and pathway databases

UniPathwayiUPA00988

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Epb41 mouse

Protein Ontology

More...
PROi
PR:Q7TT37

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000028431 Expressed in 277 organ(s), highest expression level in forebrain
GenevisibleiQ7TT37 MM

Family and domain databases

InterProiView protein in InterPro
IPR006849 Elp1
PANTHERiPTHR12747 PTHR12747, 1 hit
PfamiView protein in Pfam
PF04762 IKI3, 1 hit
PIRSFiPIRSF017233 IKAP, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiELP1_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q7TT37
Secondary accession number(s): Q3UHY6
, Q7TQH1, Q8C6B3, Q8CBI3, Q8CH82, Q8VHU5, Q8VHV9, Q9CT81
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 17, 2007
Last sequence update: March 1, 2004
Last modified: November 13, 2019
This is version 127 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  3. PATHWAY comments
    Index of metabolic and biosynthesis pathways
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