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Entry version 132 (12 Aug 2020)
Sequence version 1 (01 Oct 2003)
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Protein

RNA exonuclease 1 homolog

Gene

Rexo1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Seems to have no detectable effect on transcription elongation in vitro.By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionExonuclease, Hydrolase, Nuclease

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
RNA exonuclease 1 homolog (EC:3.1.-.-)
Alternative name(s):
Transcription elongation factor B polypeptide 3-binding protein 1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Rexo1
Synonyms:Kiaa1138, Tceb3bp1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 10

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1914182, Rexo1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002392331 – 1213RNA exonuclease 1 homologAdd BLAST1213

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei181Omega-N-methylarginineBy similarity1
Modified residuei277PhosphoserineCombined sources1
Modified residuei279PhosphoserineCombined sources1
Modified residuei353PhosphoserineCombined sources1
Modified residuei487PhosphoserineBy similarity1
Modified residuei514PhosphoserineCombined sources1
Modified residuei906PhosphoserineBy similarity1

Keywords - PTMi

Methylation, Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q7TT28

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q7TT28

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q7TT28

PeptideAtlas

More...
PeptideAtlasi
Q7TT28

PRoteomics IDEntifications database

More...
PRIDEi
Q7TT28

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q7TT28

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q7TT28

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000047417, Expressed in undifferentiated genital tubercle and 290 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q7TT28, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with TCEA2 and ELOA.

By similarity

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
211819, 1 interactor

Protein interaction database and analysis system

More...
IntActi
Q7TT28, 1 interactor

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000049705

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q7TT28, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q7TT28

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1052 – 1201ExonucleaseAdd BLAST150

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili83 – 112Sequence analysisAdd BLAST30

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi365 – 431Lys-richAdd BLAST67
Compositional biasi535 – 583Ser-richAdd BLAST49

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the REXO1/REXO3 family.Curated

Keywords - Domaini

Coiled coil

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2248, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000158590

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_006810_2_1_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q7TT28

KEGG Orthology (KO)

More...
KOi
K14570

Identification of Orthologs from Complete Genome Data

More...
OMAi
MCNYHPK

Database of Orthologous Groups

More...
OrthoDBi
227856at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q7TT28

TreeFam database of animal gene trees

More...
TreeFami
TF350172

Family and domain databases

Conserved Domains Database

More...
CDDi
cd06145, REX1_like, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.30.420.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR031736, EloA-BP1
IPR013520, Exonuclease_RNaseT/DNA_pol3
IPR034922, REX1-like_exo
IPR012337, RNaseH-like_sf
IPR036397, RNaseH_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF15870, EloA-BP1, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00479, EXOIII, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF53098, SSF53098, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 5 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q7TT28-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MLRSTGFFRS IDCPYWAGAP GGPCRRPYCH FRHRGARGPG APGSGGAASP
60 70 80 90 100
ASGLGYDPYN PELPQPPVQR ENGALGQGDG MLELELVNQA IEAVRGEVEL
110 120 130 140 150
EQRRYQELLE TARGHSAGPS ALAPCSPATS IDDDDTFSLA LTYTPGGLLS
160 170 180 190 200
PDAAYQPTPL AVPAEPGHKY SLAPSDRSQG RAAGGAGALE YVPKAVGQPR
210 220 230 240 250
RCGRPVSGGK YVVDSSKPST DLEYDPLSNY SARHLGRASA RDERATKRPR
260 270 280 290 300
GSRGAEPYTP ALKKPCDPFG GCEARFSDSE DDVTSPPKAD VSSPKAGADP
310 320 330 340 350
ESKAPGKPVS KEGREHEDGG LRGTKEMAVQ YDVEDLGQPP KAPDTVSVVK
360 370 380 390 400
PGSPARASQD ARVPKEGKAK KKKSGTSASL SHKDKVRKKD KKKEKDPARP
410 420 430 440 450
RGKEKVCTDK KKLPASNPRG KAQGPEGTKK KPSSATTVAS SGKGGSGRPS
460 470 480 490 500
STGPQDSGPG PHAPLAWKAG SAKKMSSGKL VERKARSLDE GAPQDTPKLK
510 520 530 540 550
KRALSHAELF GDESEEEDSS LGAGAPRVWP PTLPSLSSDS ESDSDSSLGL
560 570 580 590 600
DETKVPKRLK AAPPASPVPP SPLSSSSSSS GASQCAEEDV DYSALEKEVD
610 620 630 640 650
FDVDPMEECL RIFNESTSVK TEDKGRLARQ PPKEKAEEKT HAGLTTLFPG
660 670 680 690 700
QKRRVSHLCK PGKESEAPKR TPVAPPARPP TAQEVCYRRA QLAQRDSASW
710 720 730 740 750
LQAAPRPTER LSSVHISAPG EKRRIAHVPN PRLAAAPTGA KRALSASSSQ
760 770 780 790 800
ASHGPEPGSQ PLKTRTLSGM ASKTTTTVTP KRIAHSPSLQ SLKKPVIPKE
810 820 830 840 850
FGGKVPTVVR QRYLNLFIEE CLKFCSSNQE AIEKALNEEK VAYDRSPSKN
860 870 880 890 900
IYLNVAVNTL KKLRGLVPNT VPNLSKASGR RVVSHEVVLG GKLAAKTSFS
910 920 930 940 950
LSRPSSPRVE ELKGTALYSR LREYLLTQEQ LKENGYPFPH PERPGGAIIF
960 970 980 990 1000
TAEEKKPKDP SCRICCRCGT EYLVSSSGRC VRSEECYYHW GRLRRNRVAG
1010 1020 1030 1040 1050
GWETQYMCCS AAVGSVGCQV AKQHVQDGRK ENLEGFVRTF QKELPEDAHA
1060 1070 1080 1090 1100
GVFALDCEMS YTTYGLELTR VTVVDTDMQV VYDTFVKPDN EVVDYNTRFS
1110 1120 1130 1140 1150
GVTEADLVDT SITLRDVQAV LLSMFSADTI LIGHSLESDL LALKVIHGTV
1160 1170 1180 1190 1200
VDTSVLFPHR LGLPYKRSLR NLMADYLRQI IQDNVDGHSS SEDASACMHL
1210
VIWKIREDAK TKR
Length:1,213
Mass (Da):130,790
Last modified:October 1, 2003 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i2ECFAAA7A1B54363
GO
Isoform 2 (identifier: Q7TT28-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-679: Missing.
     680-735: PTAQEVCYRR...AHVPNPRLAA → MSFHTPSPVP...CTHVPCPPSA
     875-876: SK → STFLYFLLE

Note: May be due to an intron retention.Curated
Show »
Length:537
Mass (Da):59,622
Checksum:i6EB5893FEF4DC385
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
S4R246S4R246_MOUSE
RNA exonuclease 1 homolog
Rexo1
536Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A571BEI4A0A571BEI4_MOUSE
RNA exonuclease 1 homolog
Rexo1
529Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A571BG10A0A571BG10_MOUSE
RNA exonuclease 1 homolog
Rexo1
536Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
S4R1Q7S4R1Q7_MOUSE
RNA exonuclease 1 homolog
Rexo1
52Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
S4R2E9S4R2E9_MOUSE
RNA exonuclease 1 homolog
Rexo1
93Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAD32386 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti187G → S in AAH69964 (PubMed:15489334).Curated1
Sequence conflicti284T → A in AAH69964 (PubMed:15489334).Curated1
Sequence conflicti347S → P in AAH69964 (PubMed:15489334).Curated1
Sequence conflicti394E → K in AAH39623 (PubMed:15489334).Curated1
Sequence conflicti394E → K in AAH69964 (PubMed:15489334).Curated1
Sequence conflicti569P → L in BAD32386 (PubMed:15368895).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0191211 – 679Missing in isoform 2. 1 PublicationAdd BLAST679
Alternative sequenceiVSP_019122680 – 735PTAQE…PRLAA → MSFHTPSPVPRPPLRCEMRV LLTLNDRSFLVLRSSVMGLL SSCTHVPCPPSA in isoform 2. 1 PublicationAdd BLAST56
Alternative sequenceiVSP_019123875 – 876SK → STFLYFLLE in isoform 2. 1 Publication2

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK173108 mRNA Translation: BAD32386.1 Different initiation.
AK006228 mRNA Translation: BAB24471.1
AK144769 mRNA Translation: BAE26057.1
BC039623 mRNA Translation: AAH39623.1
BC052424 mRNA Translation: AAH52424.1
BC069964 mRNA Translation: AAH69964.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS24025.1 [Q7TT28-1]

NCBI Reference Sequences

More...
RefSeqi
NP_080128.2, NM_025852.3 [Q7TT28-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000057910; ENSMUSP00000049705; ENSMUSG00000047417 [Q7TT28-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
66932

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:66932

UCSC genome browser

More...
UCSCi
uc007gdq.1, mouse [Q7TT28-2]
uc007gds.1, mouse [Q7TT28-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK173108 mRNA Translation: BAD32386.1 Different initiation.
AK006228 mRNA Translation: BAB24471.1
AK144769 mRNA Translation: BAE26057.1
BC039623 mRNA Translation: AAH39623.1
BC052424 mRNA Translation: AAH52424.1
BC069964 mRNA Translation: AAH69964.1
CCDSiCCDS24025.1 [Q7TT28-1]
RefSeqiNP_080128.2, NM_025852.3 [Q7TT28-1]

3D structure databases

SMRiQ7TT28
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi211819, 1 interactor
IntActiQ7TT28, 1 interactor
STRINGi10090.ENSMUSP00000049705

PTM databases

iPTMnetiQ7TT28
PhosphoSitePlusiQ7TT28

Proteomic databases

EPDiQ7TT28
jPOSTiQ7TT28
PaxDbiQ7TT28
PeptideAtlasiQ7TT28
PRIDEiQ7TT28

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
22810, 176 antibodies

Genome annotation databases

EnsembliENSMUST00000057910; ENSMUSP00000049705; ENSMUSG00000047417 [Q7TT28-1]
GeneIDi66932
KEGGimmu:66932
UCSCiuc007gdq.1, mouse [Q7TT28-2]
uc007gds.1, mouse [Q7TT28-1]

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
57455
MGIiMGI:1914182, Rexo1

Rodent Unidentified Gene-Encoded large proteins database

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Rougei
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Phylogenomic databases

eggNOGiKOG2248, Eukaryota
GeneTreeiENSGT00940000158590
HOGENOMiCLU_006810_2_1_1
InParanoidiQ7TT28
KOiK14570
OMAiMCNYHPK
OrthoDBi227856at2759
PhylomeDBiQ7TT28
TreeFamiTF350172

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

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BioGRID-ORCSi
66932, 4 hits in 18 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
Rexo1, mouse

Protein Ontology

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PROi
PR:Q7TT28
RNActiQ7TT28, protein

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSMUSG00000047417, Expressed in undifferentiated genital tubercle and 290 other tissues
GenevisibleiQ7TT28, MM

Family and domain databases

CDDicd06145, REX1_like, 1 hit
Gene3Di3.30.420.10, 1 hit
InterProiView protein in InterPro
IPR031736, EloA-BP1
IPR013520, Exonuclease_RNaseT/DNA_pol3
IPR034922, REX1-like_exo
IPR012337, RNaseH-like_sf
IPR036397, RNaseH_sf
PfamiView protein in Pfam
PF15870, EloA-BP1, 1 hit
SMARTiView protein in SMART
SM00479, EXOIII, 1 hit
SUPFAMiSSF53098, SSF53098, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiREXO1_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q7TT28
Secondary accession number(s): Q3UMP1
, Q69ZR0, Q6NSQ6, Q6PI95, Q9DA29
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 30, 2006
Last sequence update: October 1, 2003
Last modified: August 12, 2020
This is version 132 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families
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