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Entry version 92 (10 Feb 2021)
Sequence version 2 (21 Dec 2004)
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Protein

Uncharacterized protein C20orf194 homolog

Gene
N/A
Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May act as an effector for ARL3.By similarity

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Uncharacterized protein C20orf194 homolog
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1923029, 4930402H24Rik

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002360431 – 1179Uncharacterized protein C20orf194 homologAdd BLAST1179

Proteomic databases

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q7TT23

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q7TT23

PRoteomics IDEntifications database

More...
PRIDEi
Q7TT23

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q7TT23

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q7TT23

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000027309, Expressed in rostral migratory stream and 252 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q7TT23, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q7TT23, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with ARL3.

By similarity

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000046992

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q7TT23, protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502QUJP, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000003692

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_008324_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q7TT23

Database of Orthologous Groups

More...
OrthoDBi
226711at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q7TT23

TreeFam database of animal gene trees

More...
TreeFami
TF329802

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR040342, C20orf194-like

The PANTHER Classification System

More...
PANTHERi
PTHR33664, PTHR33664, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 8 potential isoforms that are computationally mapped.Show allAlign All

Q7TT23-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDSFDPQQLG LSPARFAGTF GSGAASVSCS RLRQVQSVLT QSSKSQPDGI
60 70 80 90 100
LCILGIDSRY NEGCRELANY LLFGLYSQNA TDFEKTGFSE EILDDVILLI
110 120 130 140 150
KSDSVHLYCN PVNYRYLLPY VAHWRNLHFH CMTENEYEDE EAAEEFKISS
160 170 180 190 200
FVDMVRDCSR IGIPYSSQGH LQIFDMFVVE KWPIVQAFAL EGIGGDGFFT
210 220 230 240 250
MKYELQDVSL SLWNVYSRMD PASLENMLSE DLAVFEHQWT SFFANFDTEI
260 270 280 290 300
PFLLELSESQ AGEPFRSYFG HGMLSSHITE NSPHRQPFVL FGNHSTRDNL
310 320 330 340 350
SAGSFNFPSE GHLVRNTGPA GSFAKHMVAQ CVSPKGPLAC SRTYFFGATH
360 370 380 390 400
VPYLGDNEKL PRTTEQIRLL SQIYAAVIEA VLAGIACYAK TCSLAKAKEV
410 420 430 440 450
AEHTLESGLV FTELVPFKAD LRSKVTFHIH AVNNQGRIVP LNNEDSLSFV
460 470 480 490 500
KTARMTVYDI PDLLGGGGGG CLGSVVFSES FLTSRILVKE KDGTITPETS
510 520 530 540 550
YIILTAAIPR FCSWLVEDSE IKLSEKTLQA TKGDDCCLGT LLTGGKGAYL
560 570 580 590 600
YSNSPQSGPE EGSAYFFSGG LLFSHRHHGS IVIAKEHVDA FSFYDGDSTS
610 620 630 640 650
VVAALLIHFR SSILPHLPVH FHGSSNFLML ALFPKSKIYQ AFYSEVFSPW
660 670 680 690 700
QQQDNSGLSL KVIQEDGLSA EQKRLHSNAQ KLFSALSPPA QDWSSPKLLS
710 720 730 740 750
GKLPELDRFL QHFAIGSIGQ EPVMRAHLVG LLQQPEMSPA HEVESDKVVI
760 770 780 790 800
SIVTGLPGCH ASKLCAFLIT LHKEYGRWMV YRQIMDSSEC FHAAHFQKYL
810 820 830 840 850
SSALEAQQNR SARQSAYIRK KTRLLVVLQG YTDVIDVVQA LQTHPDPNVR
860 870 880 890 900
SYFTIGAVTV CVEPLSCYME HRFLFPKCLD QCSQGVVSNV VFTSHTAEQK
910 920 930 940 950
HPLLVQLQTL IRASNPTAAF ILAENGIVTR NEDIELILSE NSFSSPQMLR
960 970 980 990 1000
SRYLLFPGWY EGKFDAGSVF PLMVQICVWF DCPLEKTRFV SRCRAIQSSI
1010 1020 1030 1040 1050
KPSPFSGNIY HILGKVKFSD SEKTMEVCHN TLTNSLTIVP VLEGPTPPPN
1060 1070 1080 1090 1100
SRSSPQDNGQ PECYLVFIGC SLKEDSLKDW LRQSAKQRPQ RKALKTRGML
1110 1120 1130 1140 1150
TQQEIKNIHV KRHLDPLPAG YFYNGTQFVN FFGDKTDFHP LMDQFMNDYV
1160 1170
EEANREIERY NRELEQQEYR DLFEQKPKP
Length:1,179
Mass (Da):132,207
Last modified:December 21, 2004 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i9264C5F608710D1F
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 8 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q3V0A7Q3V0A7_MOUSE
RIKEN cDNA 4930402H24 gene
4930402H24Rik
1,048Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A2AKU3A2AKU3_MOUSE
RIKEN cDNA 4930402H24 gene
4930402H24Rik
265Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
B0R037B0R037_MOUSE
RIKEN cDNA 4930402H24 gene
4930402H24Rik
48Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
B0R038B0R038_MOUSE
RIKEN cDNA 4930402H24 gene
4930402H24Rik
59Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F6VYF3F6VYF3_MOUSE
RIKEN cDNA 4930402H24 gene
4930402H24Rik
212Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F6W2S3F6W2S3_MOUSE
RIKEN cDNA 4930402H24 gene
4930402H24Rik
247Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
B0R039B0R039_MOUSE
RIKEN cDNA 4930402H24 gene
4930402H24Rik
26Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F7ATN7F7ATN7_MOUSE
RIKEN cDNA 4930402H24 gene
4930402H24Rik
86Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti175D → E in BAE25462 (PubMed:16141072).Curated1
Sequence conflicti307F → L in BAE25462 (PubMed:16141072).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK143611 mRNA Translation: BAE25462.1
BC052447 mRNA Translation: AAH52447.2

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS16750.1

NCBI Reference Sequences

More...
RefSeqi
NP_083708.1, NM_029432.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000044766; ENSMUSP00000046992; ENSMUSG00000027309

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
228602

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:228602

UCSC genome browser

More...
UCSCi
uc008mjw.1, mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK143611 mRNA Translation: BAE25462.1
BC052447 mRNA Translation: AAH52447.2
CCDSiCCDS16750.1
RefSeqiNP_083708.1, NM_029432.2

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000046992

PTM databases

iPTMnetiQ7TT23
PhosphoSitePlusiQ7TT23

Proteomic databases

MaxQBiQ7TT23
PaxDbiQ7TT23
PRIDEiQ7TT23

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
23528, 75 antibodies

Genome annotation databases

EnsembliENSMUST00000044766; ENSMUSP00000046992; ENSMUSG00000027309
GeneIDi228602
KEGGimmu:228602
UCSCiuc008mjw.1, mouse

Organism-specific databases

MGIiMGI:1923029, 4930402H24Rik

Phylogenomic databases

eggNOGiENOG502QUJP, Eukaryota
GeneTreeiENSGT00390000003692
HOGENOMiCLU_008324_0_0_1
InParanoidiQ7TT23
OrthoDBi226711at2759
PhylomeDBiQ7TT23
TreeFamiTF329802

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
228602, 1 hit in 17 CRISPR screens

Protein Ontology

More...
PROi
PR:Q7TT23
RNActiQ7TT23, protein

Gene expression databases

BgeeiENSMUSG00000027309, Expressed in rostral migratory stream and 252 other tissues
ExpressionAtlasiQ7TT23, baseline and differential
GenevisibleiQ7TT23, MM

Family and domain databases

InterProiView protein in InterPro
IPR040342, C20orf194-like
PANTHERiPTHR33664, PTHR33664, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCT194_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q7TT23
Secondary accession number(s): Q3UPD4
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 16, 2006
Last sequence update: December 21, 2004
Last modified: February 10, 2021
This is version 92 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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