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Entry version 142 (12 Aug 2020)
Sequence version 1 (01 Oct 2003)
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Protein

Shugoshin 2

Gene

Sgo2

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Cooperates with PPP2CA to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I. Has a crucial role in protecting REC8 at centromeres from cleavage by separase. During meiosis, protects centromeric cohesion complexes until metaphase II/anaphase II transition, preventing premature release of meiosis-specific REC8 cohesin complexes from anaphase I centromeres. Is thus essential for an accurate gametogenesis. May act by targeting PPP2CA to centromeres, thus leading to cohesin dephosphorylation. Essential for recruiting KIF2C to the inner centromere and for correcting defective kinetochore attachments. Involved in centromeric enrichment of AUKRB in prometaphase.By similarity2 Publications

Miscellaneous

Shugoshin is Japanese for guardian spirit (as it is known to be a protector of centromeric cohesin).

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processCell cycle, Cell division, Chromosome partition, Meiosis

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-MMU-141444, Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
R-MMU-2467813, Separation of Sister Chromatids
R-MMU-2500257, Resolution of Sister Chromatid Cohesion
R-MMU-5663220, RHO GTPases Activate Formins
R-MMU-68877, Mitotic Prometaphase
R-MMU-9648025, EML4 and NUDC in mitotic spindle formation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Shugoshin 2By similarity
Alternative name(s):
Shugoshin-2
Shugoshin-like 2
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Sgo2By similarity
Synonyms:Sgol2, Sgol2aImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1098767, Sgol2a

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Centromere, Chromosome, Kinetochore, Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the 'Pathology and Biotech' section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

Mice develop normally and survive to adulthood without any apparent alteration. However, both males and females are infertile. This defect appears cytologically as complete loss of centromere cohesion at metaphase II, leading to single chromatids, and physiologically as formation of aneuploid gametes that gave rise to infertility.1 Publication

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000554401 – 1164Shugoshin 2Add BLAST1164

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei1042PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q7TSY8

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q7TSY8

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q7TSY8

PeptideAtlas

More...
PeptideAtlasi
Q7TSY8

PRoteomics IDEntifications database

More...
PRIDEi
Q7TSY8

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q7TSY8

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q7TSY8

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Ubiquitously expressed in proliferating cells. Highly expressed in the testis and oocytes.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000026039, Expressed in blastocyst and 168 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q7TSY8, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with PPP2CA.

Part of an astrin (SPAG5)-kinastrin (SKAP) complex containing KNSTRN, SPAG5, PLK1, DYNLL1 and SGO2.

Interacts with CDCA8 (By similarity).

By similarity

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
212920, 58 interactors

Protein interaction database and analysis system

More...
IntActi
Q7TSY8, 59 interactors

Molecular INTeraction database

More...
MINTi
Q7TSY8

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000027202

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q7TSY8, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q7TSY8

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili62 – 113Sequence analysisAdd BLAST52

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the shugoshin family.Curated

Keywords - Domaini

Coiled coil

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502S9Y1, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000154107

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_264434_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q7TSY8

KEGG Orthology (KO)

More...
KOi
K11581

Identification of Orthologs from Complete Genome Data

More...
OMAi
LECQDII

Database of Orthologous Groups

More...
OrthoDBi
290088at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q7TSY8

TreeFam database of animal gene trees

More...
TreeFami
TF350100

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR026706, SGO2
IPR038889, Shugoshin

The PANTHER Classification System

More...
PANTHERi
PTHR21577, PTHR21577, 2 hits
PTHR21577:SF5, PTHR21577:SF5, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q7TSY8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEYPGIKVDT VTSGIQRRVK GRIAKTNLNV SLASKIKAKI LNNSSIFKIS
60 70 80 90 100
LKHNNRALAR ALSKEKENSR RITTEKMQLQ KEVEKLNFEN TFLRLKLNTL
110 120 130 140 150
NKKLVEIESH VSNDLLTAIE ISSLSEFHQG SFLLSATKKQ RNSKQCKPAH
160 170 180 190 200
LPYARVLLTS ENDDDDGADD KWQTKCNNRT ISKTSPDSTS SVSRQPSSLH
210 220 230 240 250
QCNLKAFPPK EDNQKTCGSG HLEHTSSVDI LPNESHSDQS PKSSLSEMKT
260 270 280 290 300
APSPSLRREK LSHGNVTMRK KCVSSTPDIL YVTDLDHQPT SSPGSNWNNE
310 320 330 340 350
IHGHTNETSN NTQRNAECFL DLPSESSSEP DAKRMELVQK NTDSFHFQKT
360 370 380 390 400
VYDAADMELT ATDIGKIVAV SKSKKNQNKK KADCRKETFR KVKGASSDKK
410 420 430 440 450
RESSKRECKD GSEVGAEEEA DAARAERGAG VLDGRGDSEE PNCISSTEQP
460 470 480 490 500
SQVNTQKKRT LQNSSDQENI QNTKRRQTYT TDEQEETNPF SRHSVKFLQD
510 520 530 540 550
GKFDLCQKTL HHNLSKPSRQ TFVIRKSEKD NLFPNQEDKD TISENLEVTN
560 570 580 590 600
EFHIDDLSIE ANENVCDHET QTMLDLKKSV SAQQNQTKIN KTKQKINRRT
610 620 630 640 650
KIISVMSQVY EDNDKDIHVL EKDNFPFHTQ ANKETTSGNL ESSKEFESPL
660 670 680 690 700
LFTRDNGSLR DCKTQNVLDL HKQIPDLYPD RNESQISKIP RQKVNRKTEV
710 720 730 740 750
ISGVKCFSND QGVHCSEKDK SLLLQKDKDF PGTLKDLSEF DTPAFCNKDS
760 770 780 790 800
AKSCDYKSEM LLGLKKHDPN MQPACQDDSK AGKKLRQKVN RKTEIISKIT
810 820 830 840 850
QIHENDRGST HDSLNKKLCQ KVNISKIISQ MNQIYETINE DGNGFKSSIK
860 870 880 890 900
DCEDIKSCDF GEINSNKKEN YDPIQDPCTL VKKTKRKGSC KAGSSLAGAK
910 920 930 940 950
NRCGLQLTDS SQVQSVPLDS GLRHHPNEAD SGPGEQTNLP KMQKQSAGRS
960 970 980 990 1000
LGDAFSVSLG KEGSRPAKAV SKMTPKSKKR KLPLGCSPET HGTVEITPNT
1010 1020 1030 1040 1050
DLAKAVDSQQ TEKENYLEKE KIAKRKPDFC TKVLKPLSET CSSNIKNSSL
1060 1070 1080 1090 1100
DSMCKSSLPL SISSRKTLML EESSSLESTC IFQVGDAAHE KITTGTRNPH
1110 1120 1130 1140 1150
HRTQKSTPGS RTSLVLVDTS SVSDTNPANP ENESEGQSSH PMRRKRQCVP
1160
LNLTEPSLRS KMRR
Length:1,164
Mass (Da):130,277
Last modified:October 1, 2003 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i64BCDCE5738576D6
GO

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAH23855 differs from that shown. Contaminating sequence. Potential poly-A sequence.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti78Q → R in BAB30980 (PubMed:16141072).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
BC023855 mRNA Translation: AAH23855.1 Sequence problems.
BC044797 mRNA Translation: AAH44797.1
BC052742 mRNA Translation: AAH52742.1
AK017868 mRNA Translation: BAB30980.1
AK042448 mRNA Translation: BAC31263.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS35574.1

NCBI Reference Sequences

More...
RefSeqi
NP_001171338.1, NM_001177867.1
NP_950172.1, NM_199007.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000027202; ENSMUSP00000027202; ENSMUSG00000026039

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
68549

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:68549

UCSC genome browser

More...
UCSCi
uc007bbk.2, mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC023855 mRNA Translation: AAH23855.1 Sequence problems.
BC044797 mRNA Translation: AAH44797.1
BC052742 mRNA Translation: AAH52742.1
AK017868 mRNA Translation: BAB30980.1
AK042448 mRNA Translation: BAC31263.1
CCDSiCCDS35574.1
RefSeqiNP_001171338.1, NM_001177867.1
NP_950172.1, NM_199007.2

3D structure databases

SMRiQ7TSY8
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi212920, 58 interactors
IntActiQ7TSY8, 59 interactors
MINTiQ7TSY8
STRINGi10090.ENSMUSP00000027202

PTM databases

iPTMnetiQ7TSY8
PhosphoSitePlusiQ7TSY8

Proteomic databases

EPDiQ7TSY8
MaxQBiQ7TSY8
PaxDbiQ7TSY8
PeptideAtlasiQ7TSY8
PRIDEiQ7TSY8

Genome annotation databases

EnsembliENSMUST00000027202; ENSMUSP00000027202; ENSMUSG00000026039
GeneIDi68549
KEGGimmu:68549
UCSCiuc007bbk.2, mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
68549
MGIiMGI:1098767, Sgol2a

Phylogenomic databases

eggNOGiENOG502S9Y1, Eukaryota
GeneTreeiENSGT00940000154107
HOGENOMiCLU_264434_0_0_1
InParanoidiQ7TSY8
KOiK11581
OMAiLECQDII
OrthoDBi290088at2759
PhylomeDBiQ7TSY8
TreeFamiTF350100

Enzyme and pathway databases

ReactomeiR-MMU-141444, Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
R-MMU-2467813, Separation of Sister Chromatids
R-MMU-2500257, Resolution of Sister Chromatid Cohesion
R-MMU-5663220, RHO GTPases Activate Formins
R-MMU-68877, Mitotic Prometaphase
R-MMU-9648025, EML4 and NUDC in mitotic spindle formation

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
68549, 0 hits in 18 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Sgo2a, mouse

Protein Ontology

More...
PROi
PR:Q7TSY8
RNActiQ7TSY8, protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000026039, Expressed in blastocyst and 168 other tissues
GenevisibleiQ7TSY8, MM

Family and domain databases

InterProiView protein in InterPro
IPR026706, SGO2
IPR038889, Shugoshin
PANTHERiPTHR21577, PTHR21577, 2 hits
PTHR21577:SF5, PTHR21577:SF5, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSGO2_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q7TSY8
Secondary accession number(s): Q811I4
, Q8C9C4, Q8CGJ4, Q9CS55
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 10, 2006
Last sequence update: October 1, 2003
Last modified: August 12, 2020
This is version 142 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Direct protein sequencing, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families
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